chr21 : 39,450,801 – 39,451,150
349 bp 29 TFs 2 linked genes
This 349 bp open chromatin element is linked to SH3BGR and LCA5L and is bound by 29 transcription factors.
Linked Genes
2 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
SH3BGR 4.9 kb Proximal Proximity
LCA5L 5.0 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr21:39,445,801 – 39,456,150
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
29 transcription factors
Source
Cell type
AR 1 dataset
ChIP LNCaP-clone-FGC_DHT-DMSO GSE118247.AR.LNCaP-clone-FGC_DHT-DMSO 206 bp overlap
BRD4 1 dataset
ChIP CHL-1 GSE95585.BRD4.CHL-1 100 bp overlap
CUX1 2 datasets
ChIP K562 ENCFF902MYN 349 bp overlap
ChIP K562 ENCFF902MYN 69 bp overlap
EGR2 1 dataset
ChIP HEK293 ENCFF336LFH 243 bp overlap
EP300 1 dataset
ChIP LNCaP-FGC_ICPB112 GSE124642.EP300.LNCaP-FGC_ICPB112 65 bp overlap
ESR1 1 dataset
ChIP breast_tumor_Male_21 GSE104399.ESR1.breast_tumor_Male_21 186 bp overlap
ESRRA 1 dataset
ChIP BT-474 GSE81651.ESRRA.BT-474 176 bp overlap
FOXA1 53 datasets
ChIP 22Rv1 GSE96652.FOXA1.22Rv1 96 bp overlap
ChIP 22Rv1 GSE85558.FOXA1.22Rv1 68 bp overlap
ChIP 22Rv1_CST GSE129951.FOXA1.22Rv1_CST 205 bp overlap
ChIP 22Rv1_CST GSE123618.FOXA1.22Rv1_CST 98 bp overlap
ChIP 22Rv1_CST_Crispr GSE123618.FOXA1.22Rv1_CST_Crispr 69 bp overlap
ChIP 22Rv1_CST_Crispr-36 GSE123618.FOXA1.22Rv1_CST_Crispr-36 108 bp overlap
ChIP 22Rv1_CST_Crispr-70 GSE123618.FOXA1.22Rv1_CST_Crispr-70 98 bp overlap
ChIP 22Rv1_CST_Crispr_WT3 GSE123618.FOXA1.22Rv1_CST_Crispr_WT3 87 bp overlap
ChIP 22Rv1_Dox GSE85558.FOXA1.22Rv1_Dox 79 bp overlap
ChIP 22Rv1_EtOH GSE80742.FOXA1.22Rv1_EtOH 67 bp overlap
ChIP 22Rv1_R1881 GSE80742.FOXA1.22Rv1_R1881 69 bp overlap
ChIP 22Rv1_TFS GSE123618.FOXA1.22Rv1_TFS 124 bp overlap
ChIP 22Rv1_TFS_Crispr-36 GSE123618.FOXA1.22Rv1_TFS_Crispr-36 64 bp overlap
ChIP 22Rv1_ab GSE129951.FOXA1.22Rv1_ab 204 bp overlap
ChIP 22Rv1_i176m_CST GSE123618.FOXA1.22Rv1_i176m_CST 129 bp overlap
ChIP 22Rv1_r261g_CST GSE123618.FOXA1.22Rv1_r261g_CST 121 bp overlap
ChIP HEK293_i176m_TFS GSE123618.FOXA1.HEK293_i176m_TFS 162 bp overlap
ChIP LAPC-4_TFS_p358fs-V5 GSE123618.FOXA1.LAPC-4_TFS_p358fs-V5 93 bp overlap
ChIP LNCaP GSE64656.FOXA1.LNCaP 146 bp overlap
ChIP LNCaP_ETOH24H GSE58428.FOXA1.LNCaP_ETOH24H 138 bp overlap
ChIP LNCaP_F266S_shFOXA1 GSE128883.FOXA1.LNCaP_F266S_shFOXA1 158 bp overlap
ChIP LNCaP_FENG_shFOXA1_Ethanol GSE128883.FOXA1.LNCaP_FENG_shFOXA1_Ethanol 148 bp overlap
ChIP LNCaP_G87R_shFOXA1 GSE128883.FOXA1.LNCaP_G87R_shFOXA1 65 bp overlap
ChIP LNCaP_M253K GSE133386.FOXA1.LNCaP_M253K 80 bp overlap
ChIP LNCaP_TFS GSE123618.FOXA1.LNCaP_TFS 71 bp overlap
ChIP MCF-7 ENCFF465LTH 90 bp overlap
ChIP MCF-7 ENCSR126YEB.FOXA1.MCF-7 137 bp overlap
ChIP MCF-7_E2 GSE60270.FOXA1.MCF-7_E2 81 bp overlap
ChIP MCF-7_vehicle_ab2 GSE112969.FOXA1.MCF-7_vehicle_ab2 78 bp overlap
ChIP T-47D_CR3flp GSE99479.FOXA1.T-47D_CR3flp 56 bp overlap
ChIP T-47D_DMSO GSE84593.FOXA1.T-47D_DMSO 164 bp overlap
ChIP T-47D_JC4744 GSE126004.FOXA1.T-47D_JC4744 56 bp overlap
ChIP T-47D_JC4748 GSE126004.FOXA1.T-47D_JC4748 80 bp overlap
ChIP T-47D_shRNF2_8h GSE137579.FOXA1.T-47D_shRNF2_8h 62 bp overlap
ChIP ZR-75-1_estrogen_ab2 GSE112969.FOXA1.ZR-75-1_estrogen_ab2 76 bp overlap
ChIP ZR-75-1_vehicle_ab1 GSE112969.FOXA1.ZR-75-1_vehicle_ab1 69 bp overlap
ChIP ZR-75-1_vehicle_ab2 GSE112969.FOXA1.ZR-75-1_vehicle_ab2 91 bp overlap
ChIP ZR751 GSE72249.FOXA1.ZR751 156 bp overlap
ChIP ZR751_DEX GSE72249.FOXA1.ZR751_DEX 120 bp overlap
ChIP ZR751_E2 GSE72249.FOXA1.ZR751_E2 143 bp overlap
ChIP breast-cancer_heregulin-ICI GSE101407.FOXA1.breast-cancer_heregulin-ICI 238 bp overlap
ChIP breast_tumor_Female_2 GSE104399.FOXA1.breast_tumor_Female_2 94 bp overlap
ChIP breast_tumor_Female_3 GSE104399.FOXA1.breast_tumor_Female_3 75 bp overlap
ChIP breast_tumor_Male_1 GSE104399.FOXA1.breast_tumor_Male_1 204 bp overlap
ChIP breast_tumor_Male_14 GSE104399.FOXA1.breast_tumor_Male_14 101 bp overlap
ChIP breast_tumor_Male_19 GSE104399.FOXA1.breast_tumor_Male_19 191 bp overlap
ChIP breast_tumor_Male_3 GSE104399.FOXA1.breast_tumor_Male_3 207 bp overlap
ChIP breast_tumor_Male_6 GSE104399.FOXA1.breast_tumor_Male_6 177 bp overlap
ChIP primary-breast-cancer_B2_DSG GSE114737.FOXA1.primary-breast-cancer_B2_DSG 136 bp overlap
ChIP primary-breast-cancer_B4_DSG GSE114737.FOXA1.primary-breast-cancer_B4_DSG 162 bp overlap
ChIP primary-prostate-cancer_G2_DSG GSE114737.FOXA1.primary-prostate-cancer_G2_DSG 90 bp overlap
ChIP primary-prostate-cancer_P2_DSG GSE114737.FOXA1.primary-prostate-cancer_P2_DSG 144 bp overlap
ChIP prostate_2483_T GSE130408.FOXA1.prostate_2483_T 85 bp overlap
FOXA2 5 datasets
ChIP DE DE-FOXA2-1 349 bp overlap
ChIP DE DE-FOXA2-2 349 bp overlap
ChIP PANC-1 GSE119930.FOXA2.PANC-1 169 bp overlap
ChIP PANC-1_EV GSE119930.FOXA2.PANC-1_EV 152 bp overlap
ChIP PANC-1_HNF1B-OE GSE119930.FOXA2.PANC-1_HNF1B-OE 141 bp overlap
GATA3 1 dataset
ChIP breast_tumor_Male_21 GSE104399.GATA3.breast_tumor_Male_21 217 bp overlap
GATA4 2 datasets
ChIP DE DE-GATA4-1 291 bp overlap
ChIP DE DE-GATA4-2 349 bp overlap
GATA6 8 datasets
ChIP DE DE-GATA6-1 303 bp overlap
ChIP DE DE-GATA6-2 349 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 236 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 143 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 118 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 349 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 135 bp overlap
ChIP foregut GSE117136.GATA6.foregut 163 bp overlap
MED1 2 datasets
ChIP G296S GSE85628.MED1.G296S 213 bp overlap
ChIP G296S_2 GSE85628.MED1.G296S_2 213 bp overlap
SMAD2-3 4 datasets
ChIP HGrC1_EV-TGF GSE138496.SMAD2-3.HGrC1_EV-TGF 139 bp overlap
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 349 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 349 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 349 bp overlap
SMAD2_3 3 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 349 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 349 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 280 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 141 bp overlap
SMARCA4 1 dataset
ChIP K-562 ENCSR587OQL.SMARCA4.K-562 147 bp overlap
SMARCE1 2 datasets
ChIP K-562 ENCSR157TCS.SMARCE1.K-562 68 bp overlap
ChIP K562 ENCFF690CFF 205 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 92 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 278 bp overlap
TBX5 2 datasets
ChIP G296S GSE85628.TBX5.G296S 181 bp overlap
ChIP G296S_2 GSE85628.TBX5.G296S_2 175 bp overlap
TLE3 1 dataset
ChIP LNCaP GSE94682.TLE3.LNCaP 91 bp overlap
ZFHX2 1 dataset
ChIP HEK293 ENCFF167TUA 127 bp overlap
ZNF335 1 dataset
ChIP HEK293 ENCFF784SLD 349 bp overlap
ZNF395 1 dataset
ChIP K562 ENCFF464EIT 160 bp overlap
ZNF589 2 datasets
ChIP K562 ENCFF770FHN 349 bp overlap
ChIP K562 ENCFF770FHN 78 bp overlap
ZNF639 1 dataset
ChIP K562 ENCFF271FQR 183 bp overlap
ZNF660 1 dataset
ChIP HEK293 ENCFF282RUS 59 bp overlap
ZNF692 1 dataset
ChIP HEK293 ENCSR418MKG.ZNF692.HEK293 258 bp overlap
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