chr22 : 21,650,780 – 21,651,192

412 bp 111 TFs 3 linked genes

This 412 bp open chromatin element is linked to ENSG00000207751, ENSG00000284630, and SDF2L1 and is bound by 111 transcription factors.

Linked Genes

3 genes

Gene	Dist. to TSS	Distance	Link type
ENSG00000207751	990 bp	At TSS	Proximity
ENSG00000284630	6.6 kb	Proximal	Proximity
SDF2L1	8.5 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

111 transcription factors

APC 1 dataset

ChIP HCT-116 GSE103894.APC.HCT-116 211 bp overlap

ARID1B 1 dataset

ChIP K-562 ENCSR822CCM.ARID1B.K-562 214 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 107 bp overlap

BACH1 1 dataset

ChIP K562 ENCFF990JHI 258 bp overlap

BHLHE40 1 dataset

ChIP K-562 ENCSR000EGV.BHLHE40.K-562 131 bp overlap

BRD4 3 datasets

ChIP HCT-15 GSE73319.BRD4.HCT-15 118 bp overlap

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 132 bp overlap

ChIP MOLM-14_IBET GSE65138.BRD4.MOLM-14_IBET 153 bp overlap

CBFA2T3 1 dataset

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 270 bp overlap

CCAR2 1 dataset

ChIP K-562 GSE120104.CCAR2.K-562 150 bp overlap

CEBPB 3 datasets

ChIP K-562 ENCSR000EHE.CEBPB.K-562 217 bp overlap

ChIP K-562 ENCSR000BRQ.CEBPB.K-562 217 bp overlap

ChIP K562 ENCFF189VBN 57 bp overlap

CEBPD 1 dataset

ChIP K-562 ENCSR000BVY.CEBPD.K-562 189 bp overlap

CENPBD1 1 dataset

ChIP HepG2 ENCFF704PVQ 146 bp overlap

CHD2 1 dataset

ChIP K-562 ENCSR000EHD.CHD2.K-562 214 bp overlap

CHD4 1 dataset

ChIP SCMC GSE155861.CHD4.SCMC 286 bp overlap

CREB1 1 dataset

ChIP K-562 ENCSR000BSO.CREB1.K-562 112 bp overlap

CTCF 1 dataset

ChIP K562 ENCFF082GOI 126 bp overlap

Cebpa 4 datasets

ChIP BLaER1 ENCFF093OYK 61 bp overlap

ChIP BLaER1 ENCFF335XTP 136 bp overlap

ChIP BLaER1 ENCFF364PUR 159 bp overlap

ChIP BLaER1 ENCFF460KDD 123 bp overlap

E2F1 1 dataset

ChIP MCF-7 ENCSR000EWX.E2F1.MCF-7 255 bp overlap

E2F6 2 datasets

ChIP K562 ENCFF136LTS 228 bp overlap

ChIP K562 ENCFF136LTS 114 bp overlap

EBF1 1 dataset

ChIP NALM-6 GSE126300.EBF1.NALM-6 249 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 229 bp overlap

EP300 1 dataset

ChIP K-562 ENCSR000EGE.EP300.K-562 152 bp overlap

ESR1 1 dataset

ChIP MCF-7_G6274 GSE117941.ESR1.MCF-7_G6274 172 bp overlap

ETS1 2 datasets

ChIP K-562 ENCSR000BKQ.ETS1.K-562 130 bp overlap

ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 218 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 412 bp overlap

ChIP DE DE-FOXA2-2 412 bp overlap

GATA1 4 datasets

ChIP K-562 GSE107726.GATA1.K-562 293 bp overlap

ChIP K-562 ENCSR000EWM.GATA1.K-562 155 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 282 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 194 bp overlap

GATA2 3 datasets

ChIP K-562 ENCSR000DKA.GATA2.K-562 289 bp overlap

ChIP K-562 ENCSR000EWG.GATA2.K-562 220 bp overlap

ChIP K562 ENCFF830LLA 84 bp overlap

GATA3_Nter 1 dataset

ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 120 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 412 bp overlap

ChIP DE DE-GATA4-2 412 bp overlap

ChIP foregut GSE117136.GATA4.foregut 294 bp overlap

GATA6 11 datasets

ChIP DE DE-GATA6-1 412 bp overlap

ChIP DE DE-GATA6-2 412 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 412 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 412 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 412 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 412 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 412 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 412 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 412 bp overlap

ChIP foregut GSE117136.GATA6.foregut 262 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 246 bp overlap

GFI1B 1 dataset

ChIP K-562 ENCSR509GDT.GFI1B.K-562 173 bp overlap

GLIS1 2 datasets

ChIP HEK293 ENCFF299RSE 263 bp overlap

ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 152 bp overlap

GLIS2 2 datasets

ChIP HEK293 ENCFF446EIF 365 bp overlap

ChIP HEK293 ENCSR535DIA.GLIS2.HEK293 339 bp overlap

HDAC2 1 dataset

ChIP K-562 ENCSR000BMG.HDAC2.K-562 199 bp overlap

HDAC8 1 dataset

ChIP K-562 ENCSR000DJZ.HDAC8.K-562 205 bp overlap

HDGF 1 dataset

ChIP K-562 ENCSR197ALX.HDGF.K-562 412 bp overlap

HMGXB4 1 dataset

ChIP K562 ENCFF620JLK 169 bp overlap

HNRNPH1 1 dataset

ChIP Hep-G2 ENCSR066FXN.HNRNPH1.Hep-G2 152 bp overlap

HNRNPLL 1 dataset

ChIP K-562 ENCSR112RNT.HNRNPLL.K-562 237 bp overlap

HNRNPUL1 2 datasets

ChIP K-562 ENCSR296MXW.HNRNPUL1.K-562 234 bp overlap

ChIP K-562 GSE120104.HNRNPUL1.K-562 234 bp overlap

IFNA1 1 dataset

ChIP Huh-7_GFP GSE110511.IFNA1.Huh-7_GFP 178 bp overlap

IKZF1 1 dataset

ChIP K-562 ENCSR395HWC.IKZF1.K-562 304 bp overlap

IRF4 1 dataset

ChIP T-cell GSE136853.IRF4.T-cell 189 bp overlap

JUN 2 datasets

ChIP DE_D2 S02-DE-d2-JUN-exp1 325 bp overlap

ChIP K-562 ENCSR000EFS.JUN.K-562 211 bp overlap

JUNB 1 dataset

ChIP K-562 ENCSR000DJY.JUNB.K-562 144 bp overlap

JUND 1 dataset

ChIP K-562 ENCSR000EGN.JUND.K-562 171 bp overlap

KAT7 1 dataset

ChIP OCI-AML-3 GSE133516.KAT7.OCI-AML-3 144 bp overlap

KDM5B 1 dataset

ChIP K-562 ENCSR000AQA.KDM5B.K-562 178 bp overlap

LDB1 1 dataset

ChIP K-562 GSE142227.LDB1.K-562 231 bp overlap

MAF 1 dataset

ChIP CD4_Th1 GSE72266.MAF.CD4_Th1 174 bp overlap

MAFK 1 dataset

ChIP K-562 ENCSR000EGX.MAFK.K-562 142 bp overlap

MAX 2 datasets

ChIP K-562 ENCSR000EFV.MAX.K-562 213 bp overlap

ChIP K562 ENCFF524IJO 220 bp overlap

MAZ 1 dataset

ChIP K-562 ENCSR000EFX.MAZ.K-562 175 bp overlap

MXI1 1 dataset

ChIP K562 ENCFF336XYS 211 bp overlap

MYC 2 datasets

ChIP CC-LP-1 GSE124430.MYC.CC-LP-1 250 bp overlap

ChIP K562 ENCFF640IEK 88 bp overlap

MYNN 2 datasets

ChIP Hep-G2 ENCSR398TMP.MYNN.Hep-G2 128 bp overlap

ChIP K-562 ENCSR737LTZ.MYNN.K-562 254 bp overlap

NCOR1 1 dataset

ChIP K-562 ENCSR798ILC.NCOR1.K-562 293 bp overlap

NELFE 2 datasets

ChIP K-562_HS GSE112379.NELFE.K-562_HS 159 bp overlap

ChIP K-562_NHS GSE112379.NELFE.K-562_NHS 272 bp overlap

NEUROD1 2 datasets

ChIP K-562 ENCSR986CDX.NEUROD1.K-562 190 bp overlap

ChIP K562 ENCFF718PFO 326 bp overlap

NOTCH1 1 dataset

ChIP HPBALL GSE39263.NOTCH1.HPBALL 179 bp overlap

NR3C1 1 dataset

ChIP K-562_GLUCC ERP007081.NR3C1.K-562_GLUCC 120 bp overlap

NSD2 1 dataset

ChIP K-562 ENCSR000AVE.NSD2.K-562 257 bp overlap

PAF1 1 dataset

ChIP HCT-116_ab20662 GSE97527.PAF1.HCT-116_ab20662 151 bp overlap

PHIP 1 dataset

ChIP HEK293_ab833 GSE101646.PHIP.HEK293_ab833 152 bp overlap

POLR2A 3 datasets

ChIP K562 ENCFF137JSF 165 bp overlap

ChIP K562 ENCFF214YGX 412 bp overlap

ChIP esophagus squamous epithelium ENCFF297FPP 341 bp overlap

PRDM1 1 dataset

ChIP HEK293 ENCFF302TBP 149 bp overlap

PTBP1 1 dataset

ChIP K-562 GSE120104.PTBP1.K-562 218 bp overlap

RB1 2 datasets

ChIP K-562 ENCSR670JDQ.RB1.K-562 213 bp overlap

ChIP K-562 ENCSR506CVF.RB1.K-562 160 bp overlap

RBM39 1 dataset

ChIP K-562 ENCSR764OXF.RBM39.K-562 276 bp overlap

REST 2 datasets

ChIP K-562 GSE70482.REST.K-562 168 bp overlap

ChIP K-562 ENCSR000BMW.REST.K-562 125 bp overlap

RFX1 2 datasets

ChIP K-562 ENCSR041AXL.RFX1.K-562 265 bp overlap

ChIP K-562 ENCSR968GIB.RFX1.K-562 238 bp overlap

RNF2 1 dataset

ChIP K-562 ENCSR138FUZ.RNF2.K-562 189 bp overlap

RPA2_phospho 1 dataset

ChIP HeLa GSE108172.RPA2_phospho.HeLa 217 bp overlap

RUNX1 1 dataset

ChIP K-562 ENCSR588AKU.RUNX1.K-562 175 bp overlap

RUNX1T1 1 dataset

ChIP Kasumi-1 GSE115115.RUNX1T1.Kasumi-1 225 bp overlap

RUNX2 1 dataset

ChIP LNCaP-C4-2B GSE33889.RUNX2.LNCaP-C4-2B 291 bp overlap

SAP30 1 dataset

ChIP K-562 ENCSR000AQJ.SAP30.K-562 132 bp overlap

SIN3A 3 datasets

ChIP K-562 ENCSR920BLG.SIN3A.K-562 145 bp overlap

ChIP K562 ENCFF984TCS 103 bp overlap

ChIP PFSK-1 ENCFF218MAY 84 bp overlap

SIRT6 1 dataset

ChIP K-562 ENCSR000AUB.SIRT6.K-562 273 bp overlap

SMAD1 2 datasets

ChIP K-562 ENCSR038DJJ.SMAD1.K-562 126 bp overlap

ChIP K562 ENCFF104YGG 200 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 377 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 343 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 272 bp overlap

SMARCA4 1 dataset

ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 140 bp overlap

SNRNP70 2 datasets

ChIP K-562 ENCSR754ZHU.SNRNP70.K-562 236 bp overlap

ChIP K-562 GSE120104.SNRNP70.K-562 236 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 412 bp overlap

SOX8 1 dataset

ChIP RH4 GSE116344.SOX8.RH4 64 bp overlap

SP1 1 dataset

ChIP WTC11 ENCFF688PEU 330 bp overlap

SP2 1 dataset

ChIP K562 ENCFF891GNQ 59 bp overlap

SPI1 2 datasets

ChIP K-562_NABUT GSE74999.SPI1.K-562_NABUT 163 bp overlap

ChIP K562 ENCFF410ORC 205 bp overlap

SREBF1 1 dataset

ChIP K-562 ENCSR815ZDS.SREBF1.K-562 216 bp overlap

SRSF3 1 dataset

ChIP K-562 GSE120104.SRSF3.K-562 276 bp overlap

SUPT5H 1 dataset

ChIP HCT-116_DMSO GSE138548.SUPT5H.HCT-116_DMSO 197 bp overlap

SUPT6H 1 dataset

ChIP HCT-116_Inhibitor GSE130509.SUPT6H.HCT-116_Inhibitor 215 bp overlap

T 1 dataset

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 183 bp overlap

TAF1 1 dataset

ChIP K-562 ENCSR000BKS.TAF1.K-562 169 bp overlap

TAL1 6 datasets

ChIP K-562 GSE107726.TAL1.K-562 220 bp overlap

ChIP K-562 ENCSR000EHB.TAL1.K-562 166 bp overlap

ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 189 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 189 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 246 bp overlap

ChIP K-562_sgGal4 GSE132212.TAL1.K-562_sgGal4 216 bp overlap

TCF12 1 dataset

ChIP K-562 ENCSR744WOO.TCF12.K-562 197 bp overlap

TCF3 1 dataset

ChIP K-562 ENCSR970OJY.TCF3.K-562 213 bp overlap

TCF4 1 dataset

ChIP GEN2-2 GSE76147.TCF4.GEN2-2 71 bp overlap

U2AF1 2 datasets

ChIP Hep-G2 ENCSR868JLS.U2AF1.Hep-G2 176 bp overlap

ChIP Hep-G2 GSE120104.U2AF1.Hep-G2 156 bp overlap

UBTF 1 dataset

ChIP K-562 ENCSR000EFZ.UBTF.K-562 108 bp overlap

ZBTB2 1 dataset

ChIP K-562 ENCSR230PTV.ZBTB2.K-562 253 bp overlap

ZBTB7A 1 dataset

ChIP K-562 ENCSR000BME.ZBTB7A.K-562 212 bp overlap

ZEB2 1 dataset

ChIP K-562 ENCSR004GKA.ZEB2.K-562 245 bp overlap

ZFP64 1 dataset

ChIP Hep-G2 ENCSR487CPI.ZFP64.Hep-G2 131 bp overlap

ZIC2 1 dataset

ChIP HEK293 ENCFF033NQQ 412 bp overlap

ZNF3 1 dataset

ChIP K-562 ENCSR195QFV.ZNF3.K-562 158 bp overlap

ZNF335 1 dataset

ChIP HEK293 ENCFF784SLD 110 bp overlap

ZNF407 1 dataset

ChIP Hep-G2 ENCSR005WGY.ZNF407.Hep-G2 194 bp overlap

ZNF543 1 dataset

ChIP HepG2 ENCFF864SAR 412 bp overlap

ZNF765 1 dataset

ChIP HEK293T GSE78099.ZNF765.HEK293T 112 bp overlap

ZNF891 1 dataset

ChIP Hep-G2 ENCSR020CLV.ZNF891.Hep-G2 152 bp overlap