chrX : 69,305,681 – 69,306,164

483 bp 88 TFs 2 linked genes

This 483 bp open chromatin element is linked to PJA1 and NALF2 and is bound by 88 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
PJA1		140.5 kb	Distal	Multiome
NALF2		198.4 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

88 transcription factors

AR 1 dataset

ChIP LNCaP-abl GSE39459.AR.LNCaP-abl 117 bp overlap

ARID1A 1 dataset

ChIP HAP1 GSE108387.ARID1A.HAP1 392 bp overlap

ASH2L 3 datasets

ChIP H1 ENCFF399KAM 483 bp overlap

ChIP H1 ENCFF399KAM 407 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 483 bp overlap

BCOR 4 datasets

ChIP WA01 GSE104690.BCOR.WA01 483 bp overlap

ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 289 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 483 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 436 bp overlap

BRD4 5 datasets

ChIP HAP1 GSE108387.BRD4.HAP1 388 bp overlap

ChIP cortical-interneuron_KCl-pos GSE117508.BRD4.cortical-interneuron_KCl-pos 156 bp overlap

ChIP hESC GSE33281.BRD4.hESC 61 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 280 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 370 bp overlap

CBFB 1 dataset

ChIP ME-1 GSE46044.CBFB.ME-1 271 bp overlap

CHD7 1 dataset

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 335 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 222 bp overlap

CTCF 1 dataset

ChIP HAP1_clone21_CTCF-CRISPR GSE152721.CTCF.HAP1_clone21_CTCF-CRISPR 174 bp overlap

CTNNB1 1 dataset

ChIP hiPSC_D2 GSE132532.CTNNB1.hiPSC_D2 219 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF262VBH 67 bp overlap

E2F6 2 datasets

ChIP WA01 ENCSR000BSI.E2F6.WA01 111 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 132 bp overlap

EP300 1 dataset

ChIP osteoblast ENCSR000AUD.EP300.osteoblast 442 bp overlap

ERG 3 datasets

ChIP AMLPZ12 GSE23730.ERG.AMLPZ12 228 bp overlap

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 243 bp overlap

ChIP MCF-7 GSE23730.ERG.MCF-7 202 bp overlap

ETS1 1 dataset

ChIP cardiomyocyte_D0 GSE129986.ETS1.cardiomyocyte_D0 236 bp overlap

EWSR1-FLI1 1 dataset

Motif DE_12h DE_12h-EWSR1-FLI1_MA0149.1 18 bp overlap

EZH2 2 datasets

ChIP astrocyte ENCSR000ARR.EZH2.astrocyte 482 bp overlap

ChIP endothelial_umbilical-vein ENCSR000ATA.EZH2.endothelial_umbilical-vein 123 bp overlap

EZH2_phosphoT487 1 dataset

ChIP neuron_bipolar_doxy_4d ENCSR886KKK.EZH2_phosphoT487.neuron_bipolar_doxy_4d 483 bp overlap

Elf5 1 dataset

Motif DE_12h DE_12h-Elf5_MA0136.4 8 bp overlap

FLI1 2 datasets

ChIP A-673_1_KRAB_GFP GSE106914.FLI1.A-673_1_KRAB_GFP 339 bp overlap

ChIP TSU-1621MT GSE60477.FLI1.TSU-1621MT 390 bp overlap

FOXP1 1 dataset

ChIP H9 GSE31006.FOXP1.H9 219 bp overlap

GATA6 2 datasets

ChIP DE_D1 S41-DE-d1-GATA6-exp2 376 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 271 bp overlap

GTF2I 1 dataset

ChIP WTC11 ENCFF255XXZ 154 bp overlap

GTF3C2 1 dataset

ChIP H9 GSE94418.GTF3C2.H9 386 bp overlap

HDAC2 2 datasets

ChIP WA01 ENCSR000AVB.HDAC2.WA01 117 bp overlap

ChIP WA01 ENCSR000AVB.HDAC2.WA01 128 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 196 bp overlap

IKZF2 1 dataset

Motif DE_12h DE_12h-IKZF2_MA2326.1 6 bp overlap

JUN 5 datasets

ChIP DE_D1 S40-DE-d1-JUN-exp2 287 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 219 bp overlap

ChIP ESC S24-ESC-d0-JUN-exp1 392 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 483 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 253 bp overlap

JUND 1 dataset

ChIP WA01 ENCSR000BKP.JUND.WA01 94 bp overlap

KDM1A 5 datasets

ChIP H1 ENCFF696SGD 53 bp overlap

ChIP H1 ENCFF696SGD 125 bp overlap

ChIP NCI-H526_DMSO GSE66297.KDM1A.NCI-H526_DMSO 175 bp overlap

ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 56 bp overlap

ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 162 bp overlap

KLF4 1 dataset

ChIP HAP1 GSE130417.KLF4.HAP1 272 bp overlap

KLF9 1 dataset

ChIP GBM1A GSE62211.KLF9.GBM1A 129 bp overlap

LEF1 1 dataset

ChIP hESC GSE64758.LEF1.hESC 246 bp overlap

MED1 1 dataset

ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 304 bp overlap

MYOD1 1 dataset

ChIP IMR-90_GM GSE128527.MYOD1.IMR-90_GM 211 bp overlap

NANOG 7 datasets

ChIP H1 ENCFF747ZPQ 241 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 483 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 383 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 271 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 403 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 329 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 188 bp overlap

NCAPH2 1 dataset

ChIP HEK293 GSE97540.NCAPH2.HEK293 400 bp overlap

NEUROD1 2 datasets

ChIP D283-Med GSE92582.NEUROD1.D283-Med 291 bp overlap

ChIP D283-Med_shNEUROD1-1579 GSE92582.NEUROD1.D283-Med_shNEUROD1-1579 209 bp overlap

NIPBL 1 dataset

ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 252 bp overlap

NR5A1 1 dataset

Motif DE_12h DE_12h-NR5A1_MA1540.3 12 bp overlap

OGG1 4 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 483 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 483 bp overlap

ChIP HEK293_30_min GSE89017.OGG1.HEK293_30_min 483 bp overlap

ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 483 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 483 bp overlap

POU5F1 9 datasets

ChIP BG03 GSE21614.POU5F1.BG03 458 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 254 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 483 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 434 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 367 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 136 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 346 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 483 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 183 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 435 bp overlap

PRDM14 2 datasets

ChIP NCCIT GSE71675.PRDM14.NCCIT 82 bp overlap

ChIP primordial-germ-cell-like-cell GSE138674.PRDM14.primordial-germ-cell-like-cell 306 bp overlap

RAD21 3 datasets

ChIP HAP1 GSE152721.RAD21.HAP1 299 bp overlap

ChIP HAP1 GSE126634.RAD21.HAP1 424 bp overlap

ChIP HAP1_CTCF GSE126634.RAD21.HAP1_CTCF 483 bp overlap

RBBP5 2 datasets

ChIP WA01 ENCSR000AQC.RBBP5.WA01 130 bp overlap

ChIP WA01 ENCSR000AQC.RBBP5.WA01 228 bp overlap

RBM25 1 dataset

ChIP K562 ENCFF248CGR 87 bp overlap

RBPJ 2 datasets

Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap

ChIP GSC8-11_dasatinib GSE74557.RBPJ.GSC8-11_dasatinib 162 bp overlap

RELA 3 datasets

ChIP HEK293 GSE89017.RELA.HEK293 363 bp overlap

ChIP HEK293_30_min GSE89017.RELA.HEK293_30_min 308 bp overlap

ChIP HEK293_TNF-1h GSE75562.RELA.HEK293_TNF-1h 408 bp overlap

RUNX1 1 dataset

ChIP BCP-ALL_patient1 GSE109377.RUNX1.BCP-ALL_patient1 335 bp overlap

RXR 1 dataset

ChIP TSU-1621MT GSE60477.RXR.TSU-1621MT 233 bp overlap

RYBP 1 dataset

ChIP WA01 GSE104690.RYBP.WA01 483 bp overlap

SALL3 1 dataset

ChIP hiPSC GSE104863.SALL3.hiPSC 483 bp overlap

SIN3A 1 dataset

ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 131 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 380 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 387 bp overlap

SMAD2_3 2 datasets

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 397 bp overlap

ChIP ESC S23-ESC-d0-SMAD2_3-exp1 270 bp overlap

SMARCA4 3 datasets

ChIP NSC GSE125033.SMARCA4.NSC 268 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 447 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 355 bp overlap

SMARCB1 1 dataset

ChIP hiPSC GSE124903.SMARCB1.hiPSC 237 bp overlap

SMARCC1 3 datasets

ChIP ESC S25-ESC-d0-BAF155-exp1 404 bp overlap

ChIP hiPSC GSE124903.SMARCC1.hiPSC 384 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 443 bp overlap

SOX2 3 datasets

ChIP HNSC GSE69479.SOX2.HNSC 319 bp overlap

ChIP LK2_GFP GSE137459.SOX2.LK2_GFP 399 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 301 bp overlap

SP1 1 dataset

ChIP WA01 ENCSR000BIR.SP1.WA01 311 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 250 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 217 bp overlap

SS18-SSX 1 dataset

ChIP fibroblast_W164A GSE139053.SS18-SSX.fibroblast_W164A 239 bp overlap

STAT3 1 dataset

ChIP WA01 ERP004237.STAT3.WA01 230 bp overlap

SUZ12 1 dataset

ChIP CRL-7250_shSS18-SSX GSE108025.SUZ12.CRL-7250_shSS18-SSX 315 bp overlap

Stat5a::Stat5b 1 dataset

Motif DE_12h DE_12h-Stat5aStat5b_MA0519.2 9 bp overlap

Stat5b 1 dataset

Motif DE_12h DE_12h-Stat5b_MA1625.2 9 bp overlap

TAF1 1 dataset

ChIP WA01 ENCSR000BHO.TAF1.WA01 155 bp overlap

TBP 4 datasets

ChIP H1 ENCFF859IIO 299 bp overlap

ChIP H1 ENCFF859IIO 357 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 236 bp overlap

ChIP hiPSC_WTb_RNase-pos GSE128135.TBP.hiPSC_WTb_RNase-pos 116 bp overlap

TCF12 1 dataset

ChIP WA01 ENCSR000BIT.TCF12.WA01 269 bp overlap

TEAD4 1 dataset

ChIP ESC S26-ESC-d0-TEAD4-exp1 353 bp overlap

TFAP2A 1 dataset

ChIP WA09 GSE105081.TFAP2A.WA09 189 bp overlap

TFAP2C 2 datasets

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 483 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 471 bp overlap

TFIIIC 1 dataset

ChIP HEK293 GSE119418.TFIIIC.HEK293 442 bp overlap

TP53 1 dataset

ChIP hESC_DIFF GSE39912.TP53.hESC_DIFF 96 bp overlap

TRIM28 1 dataset

ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 357 bp overlap

YY1 1 dataset

ChIP WA01 ENCSR000BKD.YY1.WA01 246 bp overlap

ZBED4 1 dataset

Motif DE_12h DE_12h-ZBED4_MA2328.1 10 bp overlap

ZBTB48 1 dataset

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 348 bp overlap

ZBTB6 1 dataset

Motif DE_12h DE_12h-ZBTB6_MA1581.2 9 bp overlap

ZFP14 1 dataset

Motif DE_12h DE_12h-ZFP14_MA1972.1 15 bp overlap

ZFX 1 dataset

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 483 bp overlap

ZMYM3 1 dataset

ChIP K562 ENCFF361LXT 58 bp overlap

ZNF121 1 dataset

ChIP WTC11 ENCFF291API 112 bp overlap

ZNF454 1 dataset

Motif DE_12h DE_12h-ZNF454_MA1712.2 17 bp overlap

ZNF530 1 dataset

Motif DE_12h DE_12h-ZNF530_MA1981.2 14 bp overlap

Zfx 1 dataset

Motif DE_12h DE_12h-Zfx_MA0146.3 10 bp overlap