chrX : 148,504,566 – 148,505,016

450 bp 61 TFs 2 linked genes

This 450 bp open chromatin element is linked to AFF2 and ENSG00000237741 and is bound by 61 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
AFF2		3.5 kb	Proximal	Proximity
ENSG00000237741		4.0 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

61 transcription factors

AR 1 dataset

ChIP MDA-MB-453 ERP003503.AR.MDA-MB-453 301 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 281 bp overlap

BCL6 3 datasets

ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 450 bp overlap

ChIP OCI-Ly1 GSE107920.BCL6.OCI-Ly1 210 bp overlap

ChIP OCI-Ly1_si GSE107920.BCL6.OCI-Ly1_si 116 bp overlap

BRD2 1 dataset

ChIP THP-1_DMSO GSE138084.BRD2.THP-1_DMSO 288 bp overlap

BRD4 2 datasets

ChIP HAP1 GSE108387.BRD4.HAP1 436 bp overlap

ChIP KOPT-K1_E GSE54379.BRD4.KOPT-K1_E 446 bp overlap

CHD7 2 datasets

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 223 bp overlap

ChIP hiPSC_derived_neural-crest-cell GSE108506.CHD7.hiPSC_derived_neural-crest-cell 204 bp overlap

CTCF 2 datasets

ChIP Loucy ENCFF359TVQ 58 bp overlap

ChIP OCI-LY7 ENCFF086AXQ 132 bp overlap

E2F6 1 dataset

ChIP WA01 ENCSR000BSI.E2F6.WA01 113 bp overlap

EGR1 2 datasets

Motif DE_12h DE_12h-EGR1_MA0162.5 10 bp overlap

ChIP Hep-G2 ENCSR026GSW.EGR1.Hep-G2 142 bp overlap

EGR2 1 dataset

Motif DE_12h DE_12h-EGR2_MA0472.2 11 bp overlap

EGR3 1 dataset

Motif DE_12h DE_12h-EGR3_MA0732.2 11 bp overlap

EGR4 1 dataset

Motif DE_12h DE_12h-EGR4_MA0733.2 11 bp overlap

ELF1 1 dataset

ChIP A-549 GSE122203.ELF1.A-549 141 bp overlap

ESR1 1 dataset

ChIP MDA-MB-134-VI_ESTROGEN GSE51022.ESR1.MDA-MB-134-VI_ESTROGEN 223 bp overlap

FEZF2 1 dataset

Motif DE_12h DE_12h-FEZF2_MA2341.1 8 bp overlap

HLF 1 dataset

ChIP HepG2 ENCFF854JLR 142 bp overlap

HNF4A 2 datasets

ChIP Hep-G2 ENCSR469FBY.HNF4A.Hep-G2 231 bp overlap

ChIP Hep-G2 ENCSR000BLF.HNF4A.Hep-G2 150 bp overlap

KLF1 1 dataset

Motif DE_12h DE_12h-KLF1_MA0493.3 8 bp overlap

KLF10 1 dataset

Motif DE_12h DE_12h-KLF10_MA1511.2 9 bp overlap

KLF11 1 dataset

Motif DE_12h DE_12h-KLF11_MA1512.2 10 bp overlap

KLF12 1 dataset

Motif DE_12h DE_12h-KLF12_MA0742.2 9 bp overlap

KLF14 1 dataset

Motif DE_12h DE_12h-KLF14_MA0740.2 9 bp overlap

KLF15 1 dataset

Motif DE_12h DE_12h-KLF15_MA1513.2 8 bp overlap

KLF16 1 dataset

Motif DE_12h DE_12h-KLF16_MA0741.1 11 bp overlap

KLF2 1 dataset

Motif DE_12h DE_12h-KLF2_MA1515.2 8 bp overlap

KLF4 1 dataset

Motif DE_12h DE_12h-KLF4_MA0039.5 8 bp overlap

KLF5 1 dataset

Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap

KLF7 1 dataset

Motif DE_12h DE_12h-KLF7_MA1959.2 8 bp overlap

KMT2A 1 dataset

ChIP RCH-ACV GSE83671.KMT2A.RCH-ACV 450 bp overlap

MAX 3 datasets

ChIP Hep-G2 ENCSR168DYA.MAX.Hep-G2 222 bp overlap

ChIP Hep-G2 ENCSR000BTM.MAX.Hep-G2 135 bp overlap

ChIP HepG2 ENCFF507HCX 389 bp overlap

MGA 1 dataset

ChIP HepG2 ENCFF057YJE 427 bp overlap

MXI1 1 dataset

Motif DE_12h DE_12h-MXI1_MA1108.3 6 bp overlap

MYB 1 dataset

ChIP Loucy GSE94000.MYB.Loucy 147 bp overlap

NOTCH1 1 dataset

ChIP HPBALL GSE39263.NOTCH1.HPBALL 125 bp overlap

PATZ1 1 dataset

Motif DE_12h DE_12h-PATZ1_MA1961.2 11 bp overlap

PBX1 1 dataset

ChIP RCH-ACV GSE85988.PBX1.RCH-ACV 83 bp overlap

POU5F1 1 dataset

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 304 bp overlap

Plagl1 1 dataset

Motif DE_12h DE_12h-Plagl1_MA1615.2 8 bp overlap

Pparg::Rxra 1 dataset

Motif DE_12h DE_12h-PpargRxra_MA0065.3 13 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 141 bp overlap

SMARCA4 1 dataset

ChIP Aska-SS GSE108025.SMARCA4.Aska-SS 450 bp overlap

SMARCC1 1 dataset

ChIP Aska-SS GSE108025.SMARCC1.Aska-SS 450 bp overlap

SP2 1 dataset

Motif DE_12h DE_12h-SP2_MA0516.3 9 bp overlap

SP3 1 dataset

Motif DE_12h DE_12h-SP3_MA0746.3 11 bp overlap

SP4 1 dataset

Motif DE_12h DE_12h-SP4_MA0685.2 9 bp overlap

SP9 1 dataset

Motif DE_12h DE_12h-SP9_MA1564.2 10 bp overlap

TAF15 2 datasets

ChIP Hep-G2 ENCSR825MZS.TAF15.Hep-G2 170 bp overlap

ChIP Hep-G2 GSE120104.TAF15.Hep-G2 170 bp overlap

TFAP2A 1 dataset

Motif DE_12h DE_12h-TFAP2A_MA0872.1 13 bp overlap

TFAP2B 1 dataset

Motif DE_12h DE_12h-TFAP2B_MA0813.1 13 bp overlap

TFAP2C 1 dataset

Motif DE_12h DE_12h-TFAP2C_MA0815.1 13 bp overlap

USF1 1 dataset

Motif DE_12h DE_12h-USF1_MA0093.4 10 bp overlap

ZBTB24 1 dataset

Motif DE_12h DE_12h-ZBTB24_MA2330.1 10 bp overlap

ZFY 1 dataset

ChIP Hep-G2 ENCSR949OEV.ZFY.Hep-G2 134 bp overlap

ZKSCAN5 1 dataset

Motif DE_12h DE_12h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF148 1 dataset

Motif DE_12h DE_12h-ZNF148_MA1653.2 10 bp overlap

ZNF184 1 dataset

Motif DE_12h DE_12h-ZNF184_MA2120.1 13 bp overlap

ZNF257 1 dataset

Motif DE_12h DE_12h-ZNF257_MA1710.2 10 bp overlap

ZNF281 1 dataset

Motif DE_12h DE_12h-ZNF281_MA1630.3 10 bp overlap

ZNF454 1 dataset

Motif DE_12h DE_12h-ZNF454_MA1712.2 17 bp overlap

ZNF460 1 dataset

Motif DE_12h DE_12h-ZNF460_MA1596.1 16 bp overlap

Zfx 1 dataset

Motif DE_12h DE_12h-Zfx_MA0146.3 10 bp overlap