chr2 : 179,869,782 – 179,870,354

572 bp 82 TFs 2 linked genes

This 572 bp open chromatin element is linked to ZNF385B and MIR1258 and is bound by 82 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ZNF385B		8.2 kb	Proximal	Proximity
MIR1258		8.9 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

82 transcription factors

ATF4 3 datasets

Motif DE_36h DE_36h-ATF4_MA0833.3 10 bp overlap

Motif DE_48h DE_48h-ATF4_MA0833.3 10 bp overlap

Motif DE_60h DE_60h-ATF4_MA0833.3 10 bp overlap

Atoh1 1 dataset

Motif DE_48h DE_48h-Atoh1_MA1467.3 7 bp overlap

BACH1 1 dataset

Motif DE_36h DE_36h-BACH1_MA1633.2 9 bp overlap

BCL6 1 dataset

Motif DE_48h DE_48h-BCL6_MA0463.3 13 bp overlap

BCL6B 1 dataset

Motif DE_48h DE_48h-BCL6B_MA0731.1 17 bp overlap

BRD4 1 dataset

ChIP RH4_shscr GSE140115.BRD4.RH4_shscr 202 bp overlap

DUX4 1 dataset

Motif DE_36h DE_36h-DUX4_MA0468.1 11 bp overlap

DUXA 1 dataset

Motif DE_36h DE_36h-DUXA_MA0884.2 13 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 213 bp overlap

ERF::FOXI1 1 dataset

Motif DE_48h DE_48h-ERFFOXI1_MA1935.2 10 bp overlap

FLI1::FOXI1 1 dataset

Motif DE_48h DE_48h-FLI1FOXI1_MA1950.2 11 bp overlap

FOSL1::JUND 1 dataset

Motif DE_36h DE_36h-FOSL1JUND_MA1142.2 8 bp overlap

GATA1::TAL1 2 datasets

Motif DE_36h DE_36h-GATA1TAL1_MA0140.3 17 bp overlap

Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap

GATA2 2 datasets

Motif DE_36h DE_36h-GATA2_MA0036.4 7 bp overlap

Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap

GATA4 4 datasets

ChIP DE DE-GATA4-1 421 bp overlap

ChIP DE DE-GATA4-2 533 bp overlap

Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap

Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap

GATA5 2 datasets

Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap

Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap

GATA6 11 datasets

ChIP DE DE-GATA6-1 388 bp overlap

ChIP DE DE-GATA6-2 461 bp overlap

Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap

Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 541 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 518 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 501 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 523 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 517 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 549 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 464 bp overlap

Gata3 2 datasets

Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap

Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap

HAND2 1 dataset

Motif DE_48h DE_48h-HAND2_MA1638.2 6 bp overlap

IKZF1 1 dataset

Motif DE_48h DE_48h-IKZF1_MA1508.2 8 bp overlap

IRF5 1 dataset

Motif DE_48h DE_48h-IRF5_MA1420.1 14 bp overlap

JUN::JUNB 1 dataset

Motif DE_36h DE_36h-JUNJUNB_MA1132.2 8 bp overlap

KLF17 1 dataset

Motif DE_48h DE_48h-KLF17_MA1514.2 14 bp overlap

LIN54 2 datasets

Motif DE_36h DE_36h-LIN54_MA0619.2 7 bp overlap

Motif DE_48h DE_48h-LIN54_MA0619.2 7 bp overlap

MEF2A 2 datasets

Motif DE_36h DE_36h-MEF2A_MA0052.5 10 bp overlap

Motif DE_48h DE_48h-MEF2A_MA0052.5 10 bp overlap

MEF2B 2 datasets

Motif DE_36h DE_36h-MEF2B_MA0660.1 12 bp overlap

Motif DE_48h DE_48h-MEF2B_MA0660.1 12 bp overlap

MEF2C 1 dataset

Motif DE_36h DE_36h-MEF2C_MA0497.2 11 bp overlap

NEUROG2 1 dataset

Motif DE_48h DE_48h-NEUROG2_MA1642.2 7 bp overlap

NFATC3 2 datasets

Motif DE_36h DE_36h-NFATC3_MA0625.3 6 bp overlap

Motif DE_48h DE_48h-NFATC3_MA0625.3 6 bp overlap

NFATC4 2 datasets

Motif DE_36h DE_36h-NFATC4_MA1525.3 9 bp overlap

Motif DE_48h DE_48h-NFATC4_MA1525.3 9 bp overlap

NR1I2 1 dataset

Motif DE_36h DE_36h-NR1I2_MA1533.2 15 bp overlap

NR1I3 3 datasets

Motif DE_36h DE_36h-NR1I3_MA1534.2 8 bp overlap

Motif DE_48h DE_48h-NR1I3_MA1534.2 8 bp overlap

Motif DE_60h DE_60h-NR1I3_MA1534.2 8 bp overlap

NR3C1 1 dataset

ChIP A-549 ENCSR000BJR.NR3C1.A-549 99 bp overlap

Nfatc1 2 datasets

Motif DE_36h DE_36h-Nfatc1_MA0624.3 6 bp overlap

Motif DE_48h DE_48h-Nfatc1_MA0624.3 6 bp overlap

Nfatc2 2 datasets

Motif DE_36h DE_36h-Nfatc2_MA0152.3 8 bp overlap

Motif DE_48h DE_48h-Nfatc2_MA0152.3 8 bp overlap

Nr2e1 2 datasets

Motif DE_36h DE_36h-Nr2e1_MA0676.1 9 bp overlap

Motif DE_48h DE_48h-Nr2e1_MA0676.1 9 bp overlap

Nr2e3 1 dataset

Motif DE_48h DE_48h-Nr2e3_MA0164.2 6 bp overlap

PHOX2A 1 dataset

Motif DE_36h DE_36h-PHOX2A_MA0713.1 11 bp overlap

POU1F1 2 datasets

Motif DE_36h DE_36h-POU1F1_MA0784.3 14 bp overlap

Motif DE_48h DE_48h-POU1F1_MA0784.3 14 bp overlap

POU2F1 2 datasets

Motif DE_36h DE_36h-POU2F1_MA0785.2 9 bp overlap

Motif DE_48h DE_48h-POU2F1_MA0785.2 9 bp overlap

POU2F1::SOX2 2 datasets

Motif DE_36h DE_36h-POU2F1SOX2_MA1962.1 17 bp overlap

Motif DE_48h DE_48h-POU2F1SOX2_MA1962.1 17 bp overlap

POU2F2 2 datasets

Motif DE_36h DE_36h-POU2F2_MA0507.3 13 bp overlap

Motif DE_48h DE_48h-POU2F2_MA0507.3 13 bp overlap

POU2F3 2 datasets

Motif DE_36h DE_36h-POU2F3_MA0627.3 9 bp overlap

Motif DE_48h DE_48h-POU2F3_MA0627.3 9 bp overlap

POU3F1 2 datasets

Motif DE_36h DE_36h-POU3F1_MA0786.2 10 bp overlap

Motif DE_48h DE_48h-POU3F1_MA0786.2 10 bp overlap

POU3F2 2 datasets

Motif DE_36h DE_36h-POU3F2_MA0787.1 12 bp overlap

Motif DE_48h DE_48h-POU3F2_MA0787.1 12 bp overlap

POU3F3 2 datasets

Motif DE_36h DE_36h-POU3F3_MA0788.1 13 bp overlap

Motif DE_48h DE_48h-POU3F3_MA0788.1 13 bp overlap

POU3F4 2 datasets

Motif DE_36h DE_36h-POU3F4_MA0789.1 9 bp overlap

Motif DE_48h DE_48h-POU3F4_MA0789.1 9 bp overlap

POU5F1B 2 datasets

Motif DE_36h DE_36h-POU5F1B_MA0792.1 9 bp overlap

Motif DE_48h DE_48h-POU5F1B_MA0792.1 9 bp overlap

PROP1 1 dataset

Motif DE_36h DE_36h-PROP1_MA0715.1 11 bp overlap

Pou5f1::Sox2 2 datasets

Motif DE_36h DE_36h-Pou5f1Sox2_MA0142.1 15 bp overlap

Motif DE_48h DE_48h-Pou5f1Sox2_MA0142.1 15 bp overlap

RARA 1 dataset

Motif DE_48h DE_48h-RARA_MA0729.1 18 bp overlap

RELA 2 datasets

Motif DE_36h DE_36h-RELA_MA0107.1 10 bp overlap

Motif DE_48h DE_48h-RELA_MA0107.1 10 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 272 bp overlap

SMAD2_3 1 dataset

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 227 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 323 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 373 bp overlap

SPI1 1 dataset

ChIP OCI-Ly7 GSE69558.SPI1.OCI-Ly7 77 bp overlap

STAT1 1 dataset

Motif DE_48h DE_48h-STAT1_MA0137.4 9 bp overlap

STAT3 1 dataset

Motif DE_48h DE_48h-STAT3_MA0144.3 9 bp overlap

Six3 3 datasets

Motif DE_36h DE_36h-Six3_MA0631.2 11 bp overlap

Motif DE_48h DE_48h-Six3_MA0631.2 11 bp overlap

Motif DE_60h DE_60h-Six3_MA0631.2 11 bp overlap

Stat4 1 dataset

Motif DE_48h DE_48h-Stat4_MA0518.2 10 bp overlap

Stat5a 1 dataset

Motif DE_48h DE_48h-Stat5a_MA1624.2 9 bp overlap

Stat5a::Stat5b 1 dataset

Motif DE_48h DE_48h-Stat5aStat5b_MA0519.2 9 bp overlap

Stat5b 1 dataset

Motif DE_48h DE_48h-Stat5b_MA1625.2 9 bp overlap

T 1 dataset

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 240 bp overlap

TEAD1 1 dataset

Motif DE_48h DE_48h-TEAD1_MA0090.4 9 bp overlap

TEAD3 1 dataset

Motif DE_48h DE_48h-TEAD3_MA0808.1 8 bp overlap

THAP1 1 dataset

Motif DE_36h DE_36h-THAP1_MA0597.3 8 bp overlap

TRPS1 2 datasets

Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap

Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap

ZBTB24 2 datasets

Motif DE_36h DE_36h-ZBTB24_MA2330.1 10 bp overlap

Motif DE_48h DE_48h-ZBTB24_MA2330.1 10 bp overlap

ZBTB5 1 dataset

ChIP K-562 ENCSR389PWB.ZBTB5.K-562 254 bp overlap

ZIM3 2 datasets

Motif DE_48h DE_48h-ZIM3_MA1709.2 11 bp overlap

ChIP HEK293T GSE78099.ZIM3.HEK293T 272 bp overlap

ZNF324 2 datasets

Motif DE_36h DE_36h-ZNF324_MA1977.2 14 bp overlap

Motif DE_48h DE_48h-ZNF324_MA1977.2 14 bp overlap

ZNF354A 1 dataset

Motif DE_36h DE_36h-ZNF354A_MA1978.2 20 bp overlap

ZNF449 1 dataset

Motif DE_48h DE_48h-ZNF449_MA1656.2 10 bp overlap

ZNF652 1 dataset

Motif DE_48h DE_48h-ZNF652_MA1657.2 9 bp overlap

ZNF677 2 datasets

Motif DE_36h DE_36h-ZNF677_MA2101.1 12 bp overlap

Motif DE_48h DE_48h-ZNF677_MA2101.1 12 bp overlap

ZNF707 5 datasets

Motif DE_36h DE_36h-ZNF707_MA1715.1 15 bp overlap

Motif DE_48h DE_48h-ZNF707_MA1715.1 15 bp overlap

Motif DE_60h DE_60h-ZNF707_MA1715.1 15 bp overlap

ZNF76 1 dataset

Motif DE_48h DE_48h-ZNF76_MA1716.2 17 bp overlap

ZNF766 1 dataset

Motif DE_48h DE_48h-ZNF766_MA2098.1 9 bp overlap

Zic1::Zic2 1 dataset

Motif DE_48h DE_48h-Zic1Zic2_MA1628.2 7 bp overlap

Zic3 1 dataset

Motif DE_48h DE_48h-Zic3_MA0697.3 7 bp overlap