chr2 : 206,611,577 – 206,612,198
621 bp 113 TFs 3 linked genes
This 621 bp open chromatin element is linked to FASTKD2, ADAM23, and ENSG00000229321 and is bound by 113 transcription factors.
Linked Genes
3 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
FASTKD2 153.5 kb Distal Multiome
ADAM23 168.3 kb Distal Multiome
ENSG00000229321 186.5 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr2:206,606,577 – 206,617,198
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
113 transcription factors
Source
Cell type
ARID2 1 dataset
ChIP NGP_ARID1A-mut2 GSE134626.ARID2.NGP_ARID1A-mut2 322 bp overlap
Atf3 2 datasets
Motif DE_36h DE_36h-Atf3_MA1988.2 7 bp overlap
Motif DE_48h DE_48h-Atf3_MA1988.2 7 bp overlap
BACH2 2 datasets
Motif DE_36h DE_36h-BACH2_MA1470.2 19 bp overlap
Motif DE_48h DE_48h-BACH2_MA1470.2 19 bp overlap
BATF 2 datasets
Motif DE_36h DE_36h-BATF_MA1634.2 7 bp overlap
Motif DE_48h DE_48h-BATF_MA1634.2 7 bp overlap
BATF3 2 datasets
Motif DE_36h DE_36h-BATF3_MA0835.3 7 bp overlap
Motif DE_48h DE_48h-BATF3_MA0835.3 7 bp overlap
BATF::JUN 2 datasets
Motif DE_36h DE_36h-BATFJUN_MA0462.3 7 bp overlap
Motif DE_48h DE_48h-BATFJUN_MA0462.3 7 bp overlap
BNC2 2 datasets
Motif DE_36h DE_36h-BNC2_MA1928.2 7 bp overlap
Motif DE_48h DE_48h-BNC2_MA1928.2 7 bp overlap
BRD2 1 dataset
ChIP SUM159PT_MGSK2801 GSE116879.BRD2.SUM159PT_MGSK2801 210 bp overlap
BRD4 7 datasets
ChIP PC-3 GSE137207.BRD4.PC-3 349 bp overlap
ChIP PC-3_GDC-R GSE137207.BRD4.PC-3_GDC-R 467 bp overlap
ChIP PC-3_GDC-R_SAHA GSE137207.BRD4.PC-3_GDC-R_SAHA 472 bp overlap
ChIP SUM159PT_100nMtrametinib_72h GSE87418.BRD4.SUM159PT_100nMtrametinib_72h 134 bp overlap
ChIP SUM159PT_DMSO_48h GSE87418.BRD4.SUM159PT_DMSO_48h 84 bp overlap
ChIP SUM159PT_KO GSE131097.BRD4.SUM159PT_KO 284 bp overlap
ChIP SUM159PT_scramble GSE131097.BRD4.SUM159PT_scramble 494 bp overlap
CREBBP 3 datasets
ChIP PC-3 GSE147455.CREBBP.PC-3 178 bp overlap
ChIP PC-3_GDC-resist GSE147455.CREBBP.PC-3_GDC-resist 206 bp overlap
ChIP PC-3_GDC-resist GSE147455.CREBBP.PC-3_GDC-resist 131 bp overlap
CRY1 1 dataset
ChIP U2OS_cordycepin GSE130506.CRY1.U2OS_cordycepin 255 bp overlap
CTCF 1 dataset
ChIP HAP1_clone21_CTCF-CRISPR GSE152721.CTCF.HAP1_clone21_CTCF-CRISPR 190 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF364PUR 295 bp overlap
Crx 1 dataset
Motif DE_36h DE_36h-Crx_MA0467.3 6 bp overlap
DMRTA2 2 datasets
Motif DE_36h DE_36h-DMRTA2_MA1478.2 6 bp overlap
Motif DE_48h DE_48h-DMRTA2_MA1478.2 6 bp overlap
ELF1 2 datasets
Motif DE_36h DE_36h-ELF1_MA0473.4 9 bp overlap
Motif DE_48h DE_48h-ELF1_MA0473.4 9 bp overlap
ELF3 2 datasets
Motif DE_36h DE_36h-ELF3_MA0640.3 9 bp overlap
Motif DE_48h DE_48h-ELF3_MA0640.3 9 bp overlap
ELL2 1 dataset
ChIP HeLa GSE40632.ELL2.HeLa 141 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 374 bp overlap
ERG 1 dataset
ChIP aortic-endothelial-cell_D16 GSE139377.ERG.aortic-endothelial-cell_D16 146 bp overlap
ETV1 2 datasets
Motif DE_36h DE_36h-ETV1_MA0761.3 9 bp overlap
Motif DE_48h DE_48h-ETV1_MA0761.3 9 bp overlap
ETV5::HOXA2 1 dataset
Motif DE_36h DE_36h-ETV5HOXA2_MA1948.2 12 bp overlap
Erg 2 datasets
Motif DE_36h DE_36h-Erg_MA0474.4 10 bp overlap
Motif DE_48h DE_48h-Erg_MA0474.4 10 bp overlap
FOS 1 dataset
ChIP HeLa-S3 ENCSR000EZE.FOS.HeLa-S3 113 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 466 bp overlap
ChIP DE DE-FOXA2-2 528 bp overlap
FOXB1 1 dataset
Motif DE_36h DE_36h-FOXB1_MA0845.1 11 bp overlap
FOXE1 1 dataset
Motif DE_36h DE_36h-FOXE1_MA1487.3 12 bp overlap
FOXH1 1 dataset
Motif DE_36h DE_36h-FOXH1_MA0479.2 8 bp overlap
FOXN3 2 datasets
Motif DE_36h DE_36h-FOXN3_MA1489.1 8 bp overlap
Motif DE_48h DE_48h-FOXN3_MA1489.1 8 bp overlap
FOXP2 2 datasets
Motif DE_36h DE_36h-FOXP2_MA0593.2 9 bp overlap
Motif DE_48h DE_48h-FOXP2_MA0593.2 9 bp overlap
GABPA 2 datasets
Motif DE_36h DE_36h-GABPA_MA0062.4 10 bp overlap
Motif DE_48h DE_48h-GABPA_MA0062.4 10 bp overlap
GATA3 1 dataset
ChIP Kelly GSE65664.GATA3.Kelly 161 bp overlap
GATA4 6 datasets
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.GATA4.BJ1-hTERT_FOXA2_GATA4_Coexp 175 bp overlap
ChIP DE DE-GATA4-1 558 bp overlap
ChIP DE DE-GATA4-2 567 bp overlap
ChIP Hep-G2 GSE135714.GATA4.Hep-G2 321 bp overlap
ChIP foregut GSE117136.GATA4.foregut 346 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 475 bp overlap
GATA5 2 datasets
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
GATA6 11 datasets
ChIP DE DE-GATA6-1 532 bp overlap
ChIP DE DE-GATA6-2 586 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 566 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 542 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 526 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 621 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 620 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 621 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 505 bp overlap
ChIP foregut GSE117136.GATA6.foregut 368 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 313 bp overlap
GSC 1 dataset
Motif DE_36h DE_36h-GSC_MA0648.2 6 bp overlap
GSC2 1 dataset
Motif DE_36h DE_36h-GSC2_MA0891.2 6 bp overlap
HAND2 1 dataset
ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 183 bp overlap
HDAC1 1 dataset
ChIP PC-3 GSE147455.HDAC1.PC-3 87 bp overlap
HDAC2 1 dataset
ChIP PC-3 GSE147455.HDAC2.PC-3 394 bp overlap
IKZF1 2 datasets
Motif DE_36h DE_36h-IKZF1_MA1508.2 8 bp overlap
Motif DE_48h DE_48h-IKZF1_MA1508.2 8 bp overlap
IKZF2 2 datasets
Motif DE_36h DE_36h-IKZF2_MA2326.1 6 bp overlap
Motif DE_48h DE_48h-IKZF2_MA2326.1 6 bp overlap
IRF2 1 dataset
ChIP keratinocyte_DOX GSE135677.IRF2.keratinocyte_DOX 141 bp overlap
IRF3 2 datasets
Motif DE_36h DE_36h-IRF3_MA1418.2 17 bp overlap
Motif DE_48h DE_48h-IRF3_MA1418.2 17 bp overlap
IRF7 2 datasets
Motif DE_36h DE_36h-IRF7_MA0772.2 13 bp overlap
Motif DE_48h DE_48h-IRF7_MA0772.2 13 bp overlap
ISL2 4 datasets
Motif DE_36h DE_36h-ISL2_MA0914.2 6 bp overlap
Motif DE_36h DE_36h-ISL2_MA0914.2 6 bp overlap
Motif DE_48h DE_48h-ISL2_MA0914.2 6 bp overlap
Motif DE_60h DE_60h-ISL2_MA0914.2 6 bp overlap
Ikzf3 2 datasets
Motif DE_36h DE_36h-Ikzf3_MA1992.2 9 bp overlap
Motif DE_48h DE_48h-Ikzf3_MA1992.2 9 bp overlap
JUN 6 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 295 bp overlap
ChIP DE_D1 S40-DE-d1-JUN-exp2 424 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 282 bp overlap
ChIP HAEC_IL1b_4h GSE89970.JUN.HAEC_IL1b_4h 140 bp overlap
ChIP HAEC_TNFa_4h GSE89970.JUN.HAEC_TNFa_4h 184 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 415 bp overlap
Jun 2 datasets
Motif DE_36h DE_36h-Jun_MA0489.3 8 bp overlap
Motif DE_48h DE_48h-Jun_MA0489.3 8 bp overlap
MAF::NFE2 2 datasets
Motif DE_36h DE_36h-MAFNFE2_MA0501.2 11 bp overlap
Motif DE_48h DE_48h-MAFNFE2_MA0501.2 11 bp overlap
MAFF 3 datasets
Motif DE_36h DE_36h-MAFF_MA0495.4 11 bp overlap
Motif DE_48h DE_48h-MAFF_MA0495.4 11 bp overlap
Motif DE_60h DE_60h-MAFF_MA0495.4 11 bp overlap
MAFG::NFE2L1 2 datasets
Motif DE_36h DE_36h-MAFGNFE2L1_MA0089.3 11 bp overlap
Motif DE_48h DE_48h-MAFGNFE2L1_MA0089.3 11 bp overlap
MAFK 2 datasets
Motif DE_36h DE_36h-MAFK_MA0496.4 10 bp overlap
Motif DE_48h DE_48h-MAFK_MA0496.4 10 bp overlap
MAX 2 datasets
ChIP HeLa-S3 ENCSR000EZF.MAX.HeLa-S3 152 bp overlap
ChIP HeLa-S3 ENCSR000EZF.MAX.HeLa-S3 246 bp overlap
Mafb 3 datasets
Motif DE_36h DE_36h-Mafb_MA0117.3 11 bp overlap
Motif DE_48h DE_48h-Mafb_MA0117.3 11 bp overlap
Motif DE_60h DE_60h-Mafb_MA0117.3 11 bp overlap
Mafg 2 datasets
Motif DE_36h DE_36h-Mafg_MA0659.4 12 bp overlap
Motif DE_48h DE_48h-Mafg_MA0659.4 12 bp overlap
Msgn1 2 datasets
Motif DE_36h DE_36h-Msgn1_MA1524.3 10 bp overlap
Motif DE_48h DE_48h-Msgn1_MA1524.3 10 bp overlap
NELFE 1 dataset
ChIP HeLa_DOX GSE125534.NELFE.HeLa_DOX 125 bp overlap
NFKB1 1 dataset
ChIP MCF10A-Er-Src_TAM GSE115597.NFKB1.MCF10A-Er-Src_TAM 73 bp overlap
NKX2-3 1 dataset
Motif DE_36h DE_36h-NKX2-3_MA0672.2 8 bp overlap
NRL 3 datasets
Motif DE_36h DE_36h-NRL_MA0842.3 12 bp overlap
Motif DE_48h DE_48h-NRL_MA0842.3 12 bp overlap
Motif DE_60h DE_60h-NRL_MA0842.3 12 bp overlap
Nfe2l2 2 datasets
Motif DE_36h DE_36h-Nfe2l2_MA0150.3 11 bp overlap
Motif DE_48h DE_48h-Nfe2l2_MA0150.3 11 bp overlap
Nkx3-1 1 dataset
Motif DE_36h DE_36h-Nkx3-1_MA0124.3 7 bp overlap
Nkx3-2 1 dataset
Motif DE_36h DE_36h-Nkx3-2_MA0122.4 10 bp overlap
OTX1 1 dataset
Motif DE_36h DE_36h-OTX1_MA0711.2 6 bp overlap
PHOX2A 1 dataset
Motif DE_36h DE_36h-PHOX2A_MA0713.1 11 bp overlap
PHOX2B 2 datasets
ChIP CLB-Ga GSE90683.PHOX2B.CLB-Ga 301 bp overlap
Motif DE_36h DE_36h-PHOX2B_MA0681.3 12 bp overlap
PITX1 1 dataset
Motif DE_36h DE_36h-PITX1_MA0682.3 6 bp overlap
PITX3 2 datasets
Motif DE_36h DE_36h-PITX3_MA0714.2 6 bp overlap
ChIP SH-SY5Y GSE93275.PITX3.SH-SY5Y 359 bp overlap
PPARG 3 datasets
Motif DE_36h DE_36h-PPARG_MA0066.2 19 bp overlap
Motif DE_48h DE_48h-PPARG_MA0066.2 19 bp overlap
Motif DE_60h DE_60h-PPARG_MA0066.2 19 bp overlap
PROP1 1 dataset
Motif DE_36h DE_36h-PROP1_MA0715.1 11 bp overlap
Prdm14 2 datasets
Motif DE_36h DE_36h-Prdm14_MA1998.2 8 bp overlap
Motif DE_48h DE_48h-Prdm14_MA1998.2 8 bp overlap
RAD21 2 datasets
ChIP HAP1 GSE152721.RAD21.HAP1 539 bp overlap
ChIP HAP1_CTCF GSE126634.RAD21.HAP1_CTCF 621 bp overlap
RELA 1 dataset
ChIP aortic-endothelial-cell_IL1B_D14 GSE139377.RELA.aortic-endothelial-cell_IL1B_D14 187 bp overlap
RFX3 2 datasets
Motif DE_36h DE_36h-RFX3_MA0798.3 16 bp overlap
Motif DE_48h DE_48h-RFX3_MA0798.3 16 bp overlap
RHOXF1 1 dataset
Motif DE_36h DE_36h-RHOXF1_MA0719.2 6 bp overlap
RUNX3 1 dataset
Motif DE_36h DE_36h-RUNX3_MA0684.3 8 bp overlap
Rfx6 3 datasets
Motif DE_36h DE_36h-Rfx6_MA1724.2 9 bp overlap
Motif DE_48h DE_48h-Rfx6_MA1724.2 9 bp overlap
Motif DE_60h DE_60h-Rfx6_MA1724.2 9 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 480 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 436 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 346 bp overlap
SMAD2_3 4 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 282 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 382 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 408 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 285 bp overlap
SMARCA4 2 datasets
ChIP NGP_ARID1A-mut1 GSE134626.SMARCA4.NGP_ARID1A-mut1 576 bp overlap
ChIP NGP_ARID1A-mut2 GSE134626.SMARCA4.NGP_ARID1A-mut2 508 bp overlap
SMARCC1 1 dataset
ChIP DE_D1 S15-DE-d1-BAF155-exp1 501 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 434 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 449 bp overlap
SOX2 1 dataset
ChIP HCC95 GSE137459.SOX2.HCC95 331 bp overlap
SUPT5H 1 dataset
ChIP HeLa GSE125534.SUPT5H.HeLa 186 bp overlap
Six3 2 datasets
Motif DE_36h DE_36h-Six3_MA0631.2 11 bp overlap
Motif DE_48h DE_48h-Six3_MA0631.2 11 bp overlap
Sox6 2 datasets
Motif DE_36h DE_36h-Sox6_MA0515.1 10 bp overlap
Motif DE_48h DE_48h-Sox6_MA0515.1 10 bp overlap
Spz1 5 datasets
Motif DE_36h DE_36h-Spz1_MA0111.1 11 bp overlap
Motif DE_36h DE_36h-Spz1_MA0111.1 11 bp overlap
Motif DE_48h DE_48h-Spz1_MA0111.1 11 bp overlap
Motif DE_48h DE_48h-Spz1_MA0111.1 11 bp overlap
Motif DE_60h DE_60h-Spz1_MA0111.1 11 bp overlap
Stat2 2 datasets
Motif DE_36h DE_36h-Stat2_MA1623.2 10 bp overlap
Motif DE_48h DE_48h-Stat2_MA1623.2 10 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 300 bp overlap
TCF12 1 dataset
ChIP Hep-G2 ENCSR000BJG.TCF12.Hep-G2 112 bp overlap
TEAD1 1 dataset
ChIP keratinocyte GSE138727.TEAD1.keratinocyte 300 bp overlap
TP53 5 datasets
ChIP MCF-10A_Nutlin3A GSE111009.TP53.MCF-10A_Nutlin3A 112 bp overlap
ChIP MCF-7_nutlin GSE86164.TP53.MCF-7_nutlin 85 bp overlap
ChIP U2OS_NUT GSE46641.TP53.U2OS_NUT 75 bp overlap
ChIP keratinocyte GSE56674.TP53.keratinocyte 87 bp overlap
ChIP keratinocyte_CISP GSE56674.TP53.keratinocyte_CISP 177 bp overlap
TP63 1 dataset
ChIP keratinocyte GSE56674.TP63.keratinocyte 155 bp overlap
Thap11 2 datasets
Motif DE_36h DE_36h-Thap11_MA1573.2 14 bp overlap
Motif DE_48h DE_48h-Thap11_MA1573.2 14 bp overlap
ZBTB7A 2 datasets
Motif DE_36h DE_36h-ZBTB7A_MA0750.3 9 bp overlap
Motif DE_48h DE_48h-ZBTB7A_MA0750.3 9 bp overlap
ZIM3 2 datasets
Motif DE_36h DE_36h-ZIM3_MA1709.2 11 bp overlap
Motif DE_48h DE_48h-ZIM3_MA1709.2 11 bp overlap
ZKSCAN3 1 dataset
Motif DE_36h DE_36h-ZKSCAN3_MA1973.2 14 bp overlap
ZNF157 2 datasets
Motif DE_36h DE_36h-ZNF157_MA2331.1 21 bp overlap
Motif DE_48h DE_48h-ZNF157_MA2331.1 21 bp overlap
ZNF175 2 datasets
Motif DE_36h DE_36h-ZNF175_MA2332.1 9 bp overlap
Motif DE_48h DE_48h-ZNF175_MA2332.1 9 bp overlap
ZNF189 3 datasets
Motif DE_36h DE_36h-ZNF189_MA1725.2 9 bp overlap
Motif DE_48h DE_48h-ZNF189_MA1725.2 9 bp overlap
Motif DE_60h DE_60h-ZNF189_MA1725.2 9 bp overlap
ZNF213 3 datasets
Motif DE_36h DE_36h-ZNF213_MA2121.1 12 bp overlap
Motif DE_48h DE_48h-ZNF213_MA2121.1 12 bp overlap
Motif DE_60h DE_60h-ZNF213_MA2121.1 12 bp overlap
ZNF341 4 datasets
Motif DE_36h DE_36h-ZNF341_MA1655.2 8 bp overlap
Motif DE_48h DE_48h-ZNF341_MA1655.2 8 bp overlap
Motif DE_60h DE_60h-ZNF341_MA1655.2 8 bp overlap
Motif DE_72h DE_72h-ZNF341_MA1655.2 8 bp overlap
ZNF354C 1 dataset
Motif DE_36h DE_36h-ZNF354C_MA0130.1 6 bp overlap
ZNF530 2 datasets
Motif DE_36h DE_36h-ZNF530_MA1981.2 14 bp overlap
Motif DE_48h DE_48h-ZNF530_MA1981.2 14 bp overlap
ZNF549 3 datasets
Motif DE_36h DE_36h-ZNF549_MA1728.2 8 bp overlap
Motif DE_48h DE_48h-ZNF549_MA1728.2 8 bp overlap
Motif DE_60h DE_60h-ZNF549_MA1728.2 8 bp overlap
ZNF677 2 datasets
Motif DE_36h DE_36h-ZNF677_MA2101.1 12 bp overlap
Motif DE_48h DE_48h-ZNF677_MA2101.1 12 bp overlap
ZNF682 2 datasets
Motif DE_36h DE_36h-ZNF682_MA1599.2 11 bp overlap
Motif DE_48h DE_48h-ZNF682_MA1599.2 11 bp overlap
ZNF750 1 dataset
ChIP keratinocyte_diff GSE57702.ZNF750.keratinocyte_diff 192 bp overlap
ZNF766 1 dataset
Motif DE_36h DE_36h-ZNF766_MA2098.1 9 bp overlap
ZNF816 4 datasets
Motif DE_36h DE_36h-ZNF816_MA1719.2 15 bp overlap
Motif DE_36h DE_36h-ZNF816_MA1719.2 15 bp overlap
Motif DE_48h DE_48h-ZNF816_MA1719.2 15 bp overlap
Motif DE_48h DE_48h-ZNF816_MA1719.2 15 bp overlap
ZSCAN16 1 dataset
Motif DE_36h DE_36h-ZSCAN16_MA2100.1 18 bp overlap
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