chr2 : 234,932,545 – 234,933,161
616 bp 106 TFs 2 linked genes
This 616 bp open chromatin element is linked to SH3BP4 and ENSG00000235726 and is bound by 106 transcription factors.
Linked Genes
2 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
SH3BP4 19.2 kb Distal Multiome
ENSG00000235726 44.1 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr2:234,927,545 – 234,938,161
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
106 transcription factors
Source
Cell type
ASH2L 1 dataset
ChIP WA01 ENCSR850KIP.ASH2L.WA01 302 bp overlap
BCL11A 1 dataset
Motif DE_36h DE_36h-BCL11A_MA2324.1 7 bp overlap
BCOR 4 datasets
ChIP WA01 GSE104690.BCOR.WA01 296 bp overlap
ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 378 bp overlap
ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 582 bp overlap
ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 491 bp overlap
BRD4 2 datasets
ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 178 bp overlap
ChIP hESC GSE33281.BRD4.hESC 61 bp overlap
Cebpa 2 datasets
ChIP BLaER1 ENCFF335XTP 135 bp overlap
ChIP BLaER1 ENCFF364PUR 251 bp overlap
EBF1 4 datasets
Motif DE_12h DE_12h-EBF1_MA0154.5 11 bp overlap
Motif DE_36h DE_36h-EBF1_MA0154.5 11 bp overlap
Motif ES_0h ES_0h-EBF1_MA0154.5 11 bp overlap
Motif ES_0h ES_0h-EBF1_MA0154.5 11 bp overlap
EBF3 2 datasets
Motif DE_12h DE_12h-EBF3_MA1637.2 9 bp overlap
Motif ES_0h ES_0h-EBF3_MA1637.2 9 bp overlap
EBF3_P177L 1 dataset
ChIP SK-N-SH GSE90682.EBF3_P177L.SK-N-SH 195 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 222 bp overlap
EP300 1 dataset
ChIP SK-N-SH ENCSR000EHV.EP300.SK-N-SH 63 bp overlap
ERF::NHLH1 1 dataset
Motif ES_0h ES_0h-ERFNHLH1_MA1938.2 16 bp overlap
ESR1 1 dataset
ChIP primary-endometrium-cancer_E1_DSG GSE114737.ESR1.primary-endometrium-cancer_E1_DSG 255 bp overlap
EZH2 1 dataset
ChIP THP-1 GSE135024.EZH2.THP-1 406 bp overlap
EZH2_phosphoT487 1 dataset
ChIP neuron_bipolar_doxy_4d ENCSR886KKK.EZH2_phosphoT487.neuron_bipolar_doxy_4d 308 bp overlap
Ebf2 2 datasets
Motif DE_12h DE_12h-Ebf2_MA1604.2 9 bp overlap
Motif ES_0h ES_0h-Ebf2_MA1604.2 9 bp overlap
Ebf4 4 datasets
Motif DE_12h DE_12h-Ebf4_MA2122.1 11 bp overlap
Motif DE_36h DE_36h-Ebf4_MA2122.1 11 bp overlap
Motif ES_0h ES_0h-Ebf4_MA2122.1 11 bp overlap
Motif ES_0h ES_0h-Ebf4_MA2122.1 11 bp overlap
FLI1 2 datasets
ChIP A-673_1_KRAB_GFP GSE106914.FLI1.A-673_1_KRAB_GFP 234 bp overlap
ChIP A-673_2_KRAB_eSOX2_1 GSE106914.FLI1.A-673_2_KRAB_eSOX2_1 183 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-2 122 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 254 bp overlap
FOXH1 3 datasets
Motif DE_12h DE_12h-FOXH1_MA0479.2 8 bp overlap
Motif DE_24h DE_24h-FOXH1_MA0479.2 8 bp overlap
Motif ES_0h ES_0h-FOXH1_MA0479.2 8 bp overlap
FOXP4 1 dataset
ChIP WTC11 ENCFF708TAF 328 bp overlap
FUBP3 1 dataset
ChIP HepG2 ENCFF281RQN 504 bp overlap
GATA1::TAL1 3 datasets
Motif DE_12h DE_12h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_24h DE_24h-GATA1TAL1_MA0140.3 17 bp overlap
Motif ES_0h ES_0h-GATA1TAL1_MA0140.3 17 bp overlap
GATA3 2 datasets
ChIP Kelly GSE65664.GATA3.Kelly 157 bp overlap
ChIP SK-N-BE2-C GSE94822.GATA3.SK-N-BE2-C 191 bp overlap
GATA4 7 datasets
ChIP DE DE-GATA4-2 321 bp overlap
Motif DE_12h DE_12h-GATA4_MA0482.3 8 bp overlap
Motif DE_24h DE_24h-GATA4_MA0482.3 8 bp overlap
Motif ES_0h ES_0h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 329 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 309 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 336 bp overlap
GATA5 3 datasets
Motif DE_12h DE_12h-GATA5_MA0766.3 8 bp overlap
Motif DE_24h DE_24h-GATA5_MA0766.3 8 bp overlap
Motif ES_0h ES_0h-GATA5_MA0766.3 8 bp overlap
GATA6 11 datasets
ChIP DE DE-GATA6-1 287 bp overlap
ChIP DE DE-GATA6-2 316 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 415 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 368 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 466 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 385 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 453 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 463 bp overlap
ChIP foregut GSE117136.GATA6.foregut 358 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 351 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 229 bp overlap
GLIS3 1 dataset
ChIP H9_plus GSE109562.GLIS3.H9_plus 257 bp overlap
HAND2 3 datasets
ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 616 bp overlap
ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 80 bp overlap
ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 348 bp overlap
HNF1B 1 dataset
ChIP foregut GSE117136.HNF1B.foregut 287 bp overlap
HOXA3 1 dataset
ChIP Hep-G2 ENCSR999JKC.HOXA3.Hep-G2 170 bp overlap
IRF3 1 dataset
Motif ES_0h ES_0h-IRF3_MA1418.2 17 bp overlap
IRF7 1 dataset
Motif ES_0h ES_0h-IRF7_MA0772.2 13 bp overlap
IRF9 1 dataset
Motif ES_0h ES_0h-IRF9_MA0653.1 15 bp overlap
ISL1 2 datasets
ChIP SK-N-BE2-C GSE94822.ISL1.SK-N-BE2-C 261 bp overlap
ChIP SK-N-SH ENCFF285GEQ 118 bp overlap
JUN 5 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 325 bp overlap
ChIP DE_D1 S40-DE-d1-JUN-exp2 329 bp overlap
ChIP ESC S24-ESC-d0-JUN-exp1 299 bp overlap
ChIP HUES-8 GSE109524.JUN.HUES-8 562 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 378 bp overlap
KLF4 1 dataset
ChIP hiPSC GSE56567.KLF4.hiPSC 147 bp overlap
LIN54 1 dataset
Motif ES_0h ES_0h-LIN54_MA0619.2 7 bp overlap
MAF 3 datasets
Motif DE_12h DE_12h-MAF_MA1520.2 13 bp overlap
Motif DE_24h DE_24h-MAF_MA1520.2 13 bp overlap
Motif ES_0h ES_0h-MAF_MA1520.2 13 bp overlap
MAFA 3 datasets
Motif DE_12h DE_12h-MAFA_MA1521.2 13 bp overlap
Motif DE_24h DE_24h-MAFA_MA1521.2 13 bp overlap
Motif ES_0h ES_0h-MAFA_MA1521.2 13 bp overlap
MAX 2 datasets
ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 255 bp overlap
ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 403 bp overlap
MED1 1 dataset
ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 293 bp overlap
MNX1 1 dataset
ChIP Hep-G2 ENCSR108MKR.MNX1.Hep-G2 159 bp overlap
MTA1 1 dataset
ChIP Hep-G2 ENCSR983KRB.MTA1.Hep-G2 182 bp overlap
MYC 1 dataset
ChIP NCI-H2171 GSE36354.MYC.NCI-H2171 156 bp overlap
MYCN 1 dataset
ChIP COG-N-415 GSE138295.MYCN.COG-N-415 616 bp overlap
NANOG 10 datasets
ChIP GM23338 ENCSR061DGF.NANOG.GM23338 116 bp overlap
ChIP HUES-8 GSE109524.NANOG.HUES-8 512 bp overlap
ChIP WA01 ERP004238.NANOG.WA01 305 bp overlap
ChIP WA01 ENCSR000BMT.NANOG.WA01 179 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 75 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 469 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 392 bp overlap
ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 269 bp overlap
ChIP hESC GSE20650.NANOG.hESC 230 bp overlap
ChIP hESC GSE18292.NANOG.hESC 153 bp overlap
NCOR1 1 dataset
ChIP LS180 GSE39277.NCOR1.LS180 126 bp overlap
NFATC3 1 dataset
ChIP Hep-G2 GSE97661.NFATC3.Hep-G2 206 bp overlap
NIPBL 2 datasets
ChIP hESC GSE64758.NIPBL.hESC 239 bp overlap
ChIP hESC_activin GSE64758.NIPBL.hESC_activin 204 bp overlap
NR3C1 2 datasets
ChIP U2OS_GLUCC ERP007081.NR3C1.U2OS_GLUCC 69 bp overlap
ChIP U2OS_SHHIC5 GSE65847.NR3C1.U2OS_SHHIC5 239 bp overlap
ONECUT1 3 datasets
ChIP H9 ERP004206.ONECUT1.H9 151 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.ONECUT1.pancreatic-progenitor_PP1 159 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.ONECUT1.pancreatic-progenitor_PP1 197 bp overlap
PDX1 4 datasets
ChIP hiPSC GSE125768.PDX1.hiPSC 211 bp overlap
ChIP hiPSC GSE125768.PDX1.hiPSC 196 bp overlap
ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 135 bp overlap
ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 353 bp overlap
PHOX2B 2 datasets
ChIP CLB-Ga GSE90683.PHOX2B.CLB-Ga 216 bp overlap
ChIP SK-N-BE2-C GSE94822.PHOX2B.SK-N-BE2-C 145 bp overlap
POU2F1 1 dataset
Motif ES_0h ES_0h-POU2F1_MA0785.2 9 bp overlap
POU2F2 1 dataset
ChIP HNPC_UNDIF GSE74814.POU2F2.HNPC_UNDIF 128 bp overlap
POU3F1 1 dataset
Motif ES_0h ES_0h-POU3F1_MA0786.2 10 bp overlap
POU3F2 1 dataset
Motif ES_0h ES_0h-POU3F2_MA0787.1 12 bp overlap
POU3F3 1 dataset
Motif ES_0h ES_0h-POU3F3_MA0788.1 13 bp overlap
POU3F4 1 dataset
Motif ES_0h ES_0h-POU3F4_MA0789.1 9 bp overlap
POU5F1 11 datasets
ChIP DE_D1 DED1-OCT4_Batch_II 456 bp overlap
ChIP GM23338 ENCFF333SNB 311 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 494 bp overlap
ChIP NCCIT GSE36134.POU5F1.NCCIT 443 bp overlap
ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 616 bp overlap
ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 182 bp overlap
ChIP hESC ENCSR264RJX.POU5F1.hESC 130 bp overlap
ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 604 bp overlap
ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 479 bp overlap
ChIP hiPSC GSE56567.POU5F1.hiPSC 272 bp overlap
ChIP neuron_bipolar_doxy_4d ENCSR362VCG.POU5F1.neuron_bipolar_doxy_4d 147 bp overlap
POU5F1B 1 dataset
Motif ES_0h ES_0h-POU5F1B_MA0792.1 9 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 482 bp overlap
Pou5f1::Sox2 3 datasets
Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif DE_24h DE_24h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif ES_0h ES_0h-Pou5f1Sox2_MA0142.1 15 bp overlap
RARA 1 dataset
ChIP hiPSC_D3 GSE109172.RARA.hiPSC_D3 232 bp overlap
RBBP5 1 dataset
ChIP WA01 ENCSR000AQC.RBBP5.WA01 177 bp overlap
RBPJ 1 dataset
Motif ES_0h ES_0h-RBPJ_MA1116.2 6 bp overlap
REL 2 datasets
Motif DE_36h DE_36h-REL_MA0101.1 10 bp overlap
Motif ES_0h ES_0h-REL_MA0101.1 10 bp overlap
REST 1 dataset
ChIP neural ENCSR000BTV.REST.neural 110 bp overlap
RYBP 1 dataset
ChIP WA01 GSE104690.RYBP.WA01 219 bp overlap
SATB1 1 dataset
Motif ES_0h ES_0h-SATB1_MA1963.2 7 bp overlap
SIN3A 1 dataset
ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 181 bp overlap
SMAD2-3 4 datasets
ChIP HGrC1_EV GSE138496.SMAD2-3.HGrC1_EV 201 bp overlap
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 320 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 481 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 616 bp overlap
SMAD2_3 4 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 568 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 403 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 435 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 344 bp overlap
SMAD3 1 dataset
ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 167 bp overlap
SMARCA4 3 datasets
ChIP NSC GSE125033.SMARCA4.NSC 616 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 616 bp overlap
ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 320 bp overlap
SMARCB1 2 datasets
ChIP hiPSC GSE124903.SMARCB1.hiPSC 616 bp overlap
ChIP proliferating-human-fibroblast_ASO_Ctrl GSE131711.SMARCB1.proliferating-human-fibroblast_ASO_Ctrl 305 bp overlap
SMARCC1 4 datasets
ChIP DE_D1 S10-DE-d1-BAF155-exp1 267 bp overlap
ChIP SK-N-MC_shGFP GSE94275.SMARCC1.SK-N-MC_shGFP 129 bp overlap
ChIP hiPSC GSE124903.SMARCC1.hiPSC 307 bp overlap
ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 282 bp overlap
SOX2 1 dataset
ChIP hiPSC GSE56567.SOX2.hiPSC 313 bp overlap
SP1 1 dataset
ChIP H1 ENCFF263FUH 211 bp overlap
SP5 5 datasets
Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap
Motif DE_24h DE_24h-SP5_MA1965.2 6 bp overlap
Motif ES_0h ES_0h-SP5_MA1965.2 6 bp overlap
Motif ES_0h ES_0h-SP5_MA1965.2 6 bp overlap
Motif ES_0h ES_0h-SP5_MA1965.2 6 bp overlap
SPI1 1 dataset
ChIP K-562 GSE70482.SPI1.K-562 99 bp overlap
SPIB 3 datasets
Motif DE_12h DE_12h-SPIB_MA0081.3 13 bp overlap
Motif DE_24h DE_24h-SPIB_MA0081.3 13 bp overlap
Motif ES_0h ES_0h-SPIB_MA0081.3 13 bp overlap
SPIC 1 dataset
Motif ES_0h ES_0h-SPIC_MA0687.2 13 bp overlap
T 2 datasets
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 284 bp overlap
ChIP H9_MESODERM GSE60606.T.H9_MESODERM 319 bp overlap
TBX2 1 dataset
ChIP SK-N-BE2-C GSE94822.TBX2.SK-N-BE2-C 92 bp overlap
TCF3 1 dataset
ChIP NPC GSE154479.TCF3.NPC 281 bp overlap
TEAD1 2 datasets
ChIP WTC11 ENCFF502QUV 344 bp overlap
ChIP pancreas_12D ERP008682.TEAD1.pancreas_12D 144 bp overlap
TEAD4 2 datasets
ChIP BE2C GSE84389.TEAD4.BE2C 216 bp overlap
ChIP SK-N-BE2 GSE84389.TEAD4.SK-N-BE2 216 bp overlap
TFAP2A 2 datasets
Motif DE_36h DE_36h-TFAP2A_MA0810.2 11 bp overlap
Motif ES_0h ES_0h-TFAP2A_MA0810.2 11 bp overlap
THRA 2 datasets
Motif DE_12h DE_12h-THRA_MA1969.2 18 bp overlap
Motif ES_0h ES_0h-THRA_MA1969.2 18 bp overlap
THRB 1 dataset
Motif DE_12h DE_12h-THRB_MA1576.2 18 bp overlap
TP53 2 datasets
ChIP H9_mesoderm GSE142050.TP53.H9_mesoderm 282 bp overlap
ChIP hESC_DIFF GSE39912.TP53.hESC_DIFF 337 bp overlap
TRIM28 1 dataset
ChIP hESC GSE115387.TRIM28.hESC 219 bp overlap
TSHZ2 1 dataset
ChIP SK-N-SH ENCFF182EBB 128 bp overlap
TWIST1 2 datasets
ChIP BE2C GSE80151.TWIST1.BE2C 122 bp overlap
ChIP SK-N-BE2-C GSE80151.TWIST1.SK-N-BE2-C 122 bp overlap
ZNF16 3 datasets
Motif DE_12h DE_12h-ZNF16_MA1654.2 21 bp overlap
Motif DE_24h DE_24h-ZNF16_MA1654.2 21 bp overlap
Motif ES_0h ES_0h-ZNF16_MA1654.2 21 bp overlap
ZNF184 2 datasets
Motif ES_0h ES_0h-ZNF184_MA2120.1 13 bp overlap
ChIP WTC11 ENCFF352POG 423 bp overlap
ZNF213 1 dataset
Motif DE_36h DE_36h-ZNF213_MA2121.1 12 bp overlap
ZNF263 4 datasets
Motif DE_12h DE_12h-ZNF263_MA0528.3 7 bp overlap
Motif DE_24h DE_24h-ZNF263_MA0528.3 7 bp overlap
Motif ES_0h ES_0h-ZNF263_MA0528.3 7 bp overlap
Motif ES_0h ES_0h-ZNF263_MA0528.3 7 bp overlap
ZNF317 2 datasets
ChIP HEK293 GSE76494.ZNF317.HEK293 188 bp overlap
ChIP WTC11 ENCFF537KXI 357 bp overlap
ZNF331 3 datasets
Motif DE_12h DE_12h-ZNF331_MA1726.2 10 bp overlap
Motif DE_24h DE_24h-ZNF331_MA1726.2 10 bp overlap
Motif ES_0h ES_0h-ZNF331_MA1726.2 10 bp overlap
ZNF354C 1 dataset
Motif DE_12h DE_12h-ZNF354C_MA0130.1 6 bp overlap
ZNF528 1 dataset
Motif DE_36h DE_36h-ZNF528_MA1597.1 17 bp overlap
ZNF667 3 datasets
Motif DE_24h DE_24h-ZNF667_MA1984.2 11 bp overlap
Motif DE_36h DE_36h-ZNF667_MA1984.2 11 bp overlap
Motif ES_0h ES_0h-ZNF667_MA1984.2 11 bp overlap
ZNF682 1 dataset
Motif DE_36h DE_36h-ZNF682_MA1599.2 11 bp overlap
ZNF684 3 datasets
Motif DE_12h DE_12h-ZNF684_MA1600.2 14 bp overlap
Motif DE_24h DE_24h-ZNF684_MA1600.2 14 bp overlap
Motif ES_0h ES_0h-ZNF684_MA1600.2 14 bp overlap
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