chr1 : 58,853,148 – 58,854,080

932 bp 53 TFs 2 linked genes

This 932 bp open chromatin element is linked to JUN and MYSM1 and is bound by 53 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
JUN		69.6 kb	Distal	Multiome
MYSM1		153.6 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

53 transcription factors

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 339 bp overlap

CTNNB1 1 dataset

ChIP hiPSC_D2 GSE132532.CTNNB1.hiPSC_D2 209 bp overlap

E2F6 3 datasets

ChIP H1 ENCFF785DWK 364 bp overlap

ChIP H1 ENCFF785DWK 451 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 124 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 275 bp overlap

ERF::SREBF2 1 dataset

Motif DE_48h DE_48h-ERFSREBF2_MA1939.2 16 bp overlap

ETV5::FOXO1 2 datasets

Motif DE_48h DE_48h-ETV5FOXO1_MA1947.2 10 bp overlap

Motif DE_60h DE_60h-ETV5FOXO1_MA1947.2 10 bp overlap

FLI1::FOXI1 1 dataset

Motif DE_60h DE_60h-FLI1FOXI1_MA1950.2 11 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 483 bp overlap

ChIP DE DE-FOXA2-2 538 bp overlap

FOXO1::ELF1 1 dataset

Motif DE_60h DE_60h-FOXO1ELF1_MA1953.2 13 bp overlap

FOXO1::ELK1 1 dataset

Motif DE_60h DE_60h-FOXO1ELK1_MA1954.2 13 bp overlap

FOXO1::FLI1 1 dataset

Motif DE_60h DE_60h-FOXO1FLI1_MA1956.2 13 bp overlap

GATA4 6 datasets

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.GATA4.BJ1-hTERT_FOXA2_GATA4_Coexp 261 bp overlap

ChIP DE DE-GATA4-1 662 bp overlap

ChIP DE DE-GATA4-2 801 bp overlap

ChIP Hep-G2 GSE135714.GATA4.Hep-G2 419 bp overlap

ChIP foregut GSE117136.GATA4.foregut 606 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 393 bp overlap

GATA6 5 datasets

ChIP AGS GSE51705.GATA6.AGS 381 bp overlap

ChIP DE DE-GATA6-1 595 bp overlap

ChIP DE DE-GATA6-2 864 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 610 bp overlap

ChIP foregut GSE117136.GATA6.foregut 498 bp overlap

HMGB2 1 dataset

ChIP HUVEC-C GSE98245.HMGB2.HUVEC-C 164 bp overlap

HNRNPK 2 datasets

ChIP Hep-G2 GSE120104.HNRNPK.Hep-G2 278 bp overlap

ChIP Hep-G2 ENCSR519QAA.HNRNPK.Hep-G2 263 bp overlap

JARID2 1 dataset

ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 287 bp overlap

JUN 1 dataset

ChIP MDA-MB-231 GSE112444.JUN.MDA-MB-231 60 bp overlap

KDM1A 1 dataset

ChIP NB4_DMSO GSE128528.KDM1A.NB4_DMSO 216 bp overlap

MED1 2 datasets

ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 381 bp overlap

ChIP RH4 GSE83726.MED1.RH4 232 bp overlap

MSC 2 datasets

Motif DE_48h DE_48h-MSC_MA0665.1 10 bp overlap

Motif DE_60h DE_60h-MSC_MA0665.1 10 bp overlap

NANOG 2 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 190 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 363 bp overlap

NCOA1 1 dataset

ChIP LS180 GSE39277.NCOA1.LS180 166 bp overlap

NKX2-2 2 datasets

Motif DE_48h DE_48h-NKX2-2_MA1645.2 8 bp overlap

Motif DE_60h DE_60h-NKX2-2_MA1645.2 8 bp overlap

NKX2-5 2 datasets

Motif DE_48h DE_48h-NKX2-5_MA0063.3 7 bp overlap

Motif DE_60h DE_60h-NKX2-5_MA0063.3 7 bp overlap

NR4A1 2 datasets

Motif DE_48h DE_48h-NR4A1_MA1112.3 8 bp overlap

Motif DE_60h DE_60h-NR4A1_MA1112.3 8 bp overlap

Nr2e1 2 datasets

Motif DE_48h DE_48h-Nr2e1_MA0676.1 9 bp overlap

Motif DE_60h DE_60h-Nr2e1_MA0676.1 9 bp overlap

OLIG2 1 dataset

ChIP brain-prefrontal-cortex_2017011 GSE129039.OLIG2.brain-prefrontal-cortex_2017011 267 bp overlap

PAX3 2 datasets

Motif DE_48h DE_48h-PAX3_MA1546.2 14 bp overlap

Motif DE_60h DE_60h-PAX3_MA1546.2 14 bp overlap

PCBP2 2 datasets

ChIP Hep-G2 ENCSR945NSF.PCBP2.Hep-G2 392 bp overlap

ChIP Hep-G2 GSE120104.PCBP2.Hep-G2 392 bp overlap

PHIP 1 dataset

ChIP HEK293_ab833 GSE101646.PHIP.HEK293_ab833 179 bp overlap

PPARA::RXRA 2 datasets

Motif DE_48h DE_48h-PPARARXRA_MA1148.2 17 bp overlap

Motif DE_60h DE_60h-PPARARXRA_MA1148.2 17 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 162 bp overlap

RORA 1 dataset

Motif DE_48h DE_48h-RORA_MA0072.2 11 bp overlap

SCRT1 2 datasets

Motif DE_48h DE_48h-SCRT1_MA0743.3 10 bp overlap

Motif DE_60h DE_60h-SCRT1_MA0743.3 10 bp overlap

SCRT2 2 datasets

Motif DE_48h DE_48h-SCRT2_MA0744.3 10 bp overlap

Motif DE_60h DE_60h-SCRT2_MA0744.3 10 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 643 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 414 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 397 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 387 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 185 bp overlap

SOX10 3 datasets

Motif DE_48h DE_48h-SOX10_MA0442.3 6 bp overlap

Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 439 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 890 bp overlap

SOX2 1 dataset

ChIP hiPSC GSE56567.SOX2.hiPSC 161 bp overlap

SOX4 1 dataset

Motif DE_60h DE_60h-SOX4_MA0867.3 8 bp overlap

SREBF1 1 dataset

Motif DE_48h DE_48h-SREBF1_MA0829.3 10 bp overlap

Sox11 1 dataset

Motif DE_60h DE_60h-Sox11_MA0869.3 8 bp overlap

TBL1X 1 dataset

ChIP HEK293T GSE35197.TBL1X.HEK293T 67 bp overlap

ZFP69B 1 dataset

ChIP HEK293T GSE78099.ZFP69B.HEK293T 231 bp overlap

ZNF148 1 dataset

ChIP K-562 ENCSR018MSO.ZNF148.K-562 264 bp overlap

ZNF283 1 dataset

ChIP HEK293T GSE78099.ZNF283.HEK293T 157 bp overlap

ZNF467 1 dataset

ChIP HEK293 GSE76494.ZNF467.HEK293 216 bp overlap

ZNF652 1 dataset

ChIP Hep-G2 ENCSR502GAX.ZNF652.Hep-G2 114 bp overlap

ZNF75A 2 datasets

Motif DE_48h DE_48h-ZNF75A_MA2097.1 12 bp overlap

Motif DE_60h DE_60h-ZNF75A_MA2097.1 12 bp overlap

Zfp335 2 datasets

Motif DE_48h DE_48h-Zfp335_MA2002.2 7 bp overlap

Motif DE_60h DE_60h-Zfp335_MA2002.2 7 bp overlap