chr4 : 56,323,870 – 56,324,663
793 bp 70 TFs 5 linked genes
This 793 bp open chromatin element is linked to 5 target genes and is bound by 70 transcription factors.
Linked Genes
5 genes
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
AASDH 63.1 kb Distal Multiome
PPAT 111.3 kb Distal Multiome
PAICS 111.9 kb Distal Multiome
SRP72 143.3 kb Distal Multiome
CRACD 275.3 kb Distal Multiome+HiCAR
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr4:56,318,870 – 56,329,663
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
70 transcription factors
Source
Cell type
AR 2 datasets
ChIP LNCaP GSE80256.AR.LNCaP 215 bp overlap
ChIP MCF-7 GSE48930.AR.MCF-7 176 bp overlap
ATF2 3 datasets
Motif DE_48h DE_48h-ATF2_MA1632.2 10 bp overlap
Motif DE_60h DE_60h-ATF2_MA1632.2 10 bp overlap
Motif DE_72h DE_72h-ATF2_MA1632.2 10 bp overlap
Ahr::Arnt 2 datasets
Motif DE_60h DE_60h-AhrArnt_MA0006.2 5 bp overlap
Motif DE_72h DE_72h-AhrArnt_MA0006.2 5 bp overlap
BACH2 3 datasets
Motif DE_48h DE_48h-BACH2_MA1470.2 19 bp overlap
Motif DE_60h DE_60h-BACH2_MA1470.2 19 bp overlap
Motif DE_72h DE_72h-BACH2_MA1470.2 19 bp overlap
BARHL1 3 datasets
Motif DE_48h DE_48h-BARHL1_MA0877.4 6 bp overlap
Motif DE_60h DE_60h-BARHL1_MA0877.4 6 bp overlap
Motif DE_72h DE_72h-BARHL1_MA0877.4 6 bp overlap
BARHL2 3 datasets
Motif DE_48h DE_48h-BARHL2_MA0635.2 6 bp overlap
Motif DE_60h DE_60h-BARHL2_MA0635.2 6 bp overlap
Motif DE_72h DE_72h-BARHL2_MA0635.2 6 bp overlap
BARX2 2 datasets
Motif DE_36h DE_36h-BARX2_MA1471.2 9 bp overlap
Motif DE_72h DE_72h-BARX2_MA1471.2 9 bp overlap
BRD1 1 dataset
ChIP HUES-64 GSE104059.BRD1.HUES-64 266 bp overlap
CDKN1B 1 dataset
ChIP MDA-MB-231 GSE112444.CDKN1B.MDA-MB-231 221 bp overlap
CREM 1 dataset
ChIP K-562 ENCSR077DKV.CREM.K-562 93 bp overlap
CTCF 1 dataset
ChIP U-937 ERP008568.CTCF.U-937 300 bp overlap
DNMT3B 1 dataset
ChIP HUES-8_TripleKO-TET1-2-3 GSE99346.DNMT3B.HUES-8_TripleKO-TET1-2-3 368 bp overlap
EGR1 4 datasets
ChIP K-562 ENCSR024CNP.EGR1.K-562 248 bp overlap
ChIP K-562 ENCSR000BNE.EGR1.K-562 162 bp overlap
ChIP K562 ENCFF006PJY 245 bp overlap
ChIP K562 ENCFF895KGN 385 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 350 bp overlap
ERG 1 dataset
ChIP SKNO-1 GSE23730.ERG.SKNO-1 204 bp overlap
FOXA1 1 dataset
ChIP LNCaP_R1881 GSE69043.FOXA1.LNCaP_R1881 111 bp overlap
FOXA2 3 datasets
ChIP DE DE-FOXA2-1 509 bp overlap
ChIP DE DE-FOXA2-2 87 bp overlap
ChIP DE DE-FOXA2-2 506 bp overlap
GATA1::TAL1 3 datasets
Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_60h DE_60h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_72h DE_72h-GATA1TAL1_MA0140.3 17 bp overlap
GATA2 1 dataset
ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 328 bp overlap
GATA4 6 datasets
ChIP DE DE-GATA4-1 523 bp overlap
ChIP DE DE-GATA4-2 86 bp overlap
ChIP DE DE-GATA4-2 563 bp overlap
ChIP Hep-G2 GSE135714.GATA4.Hep-G2 297 bp overlap
ChIP foregut GSE117136.GATA4.foregut 541 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 450 bp overlap
GATA6 14 datasets
ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 198 bp overlap
ChIP DE DE-GATA6-1 478 bp overlap
ChIP DE DE-GATA6-2 77 bp overlap
ChIP DE DE-GATA6-2 542 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 519 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 524 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 521 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 596 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 590 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 551 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 536 bp overlap
ChIP foregut GSE117136.GATA6.foregut 586 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 381 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 377 bp overlap
HNF1A 2 datasets
Motif DE_36h DE_36h-HNF1A_MA0046.3 13 bp overlap
Motif DE_72h DE_72h-HNF1A_MA0046.3 13 bp overlap
HNF1B 3 datasets
Motif DE_36h DE_36h-HNF1B_MA0153.2 13 bp overlap
Motif DE_72h DE_72h-HNF1B_MA0153.2 13 bp overlap
ChIP foregut GSE117136.HNF1B.foregut 431 bp overlap
HOXA3 3 datasets
Motif DE_36h DE_36h-HOXA3_MA2119.1 7 bp overlap
Motif DE_60h DE_60h-HOXA3_MA2119.1 7 bp overlap
Motif DE_72h DE_72h-HOXA3_MA2119.1 7 bp overlap
HOXA4 3 datasets
Motif DE_36h DE_36h-HOXA4_MA1496.2 7 bp overlap
Motif DE_60h DE_60h-HOXA4_MA1496.2 7 bp overlap
Motif DE_72h DE_72h-HOXA4_MA1496.2 7 bp overlap
HOXA5 3 datasets
Motif DE_36h DE_36h-HOXA5_MA0158.2 8 bp overlap
Motif DE_60h DE_60h-HOXA5_MA0158.2 8 bp overlap
Motif DE_72h DE_72h-HOXA5_MA0158.2 8 bp overlap
HOXB4 3 datasets
Motif DE_36h DE_36h-HOXB4_MA1499.2 6 bp overlap
Motif DE_60h DE_60h-HOXB4_MA1499.2 6 bp overlap
Motif DE_72h DE_72h-HOXB4_MA1499.2 6 bp overlap
HOXC4 3 datasets
Motif DE_36h DE_36h-HOXC4_MA1504.2 6 bp overlap
Motif DE_60h DE_60h-HOXC4_MA1504.2 6 bp overlap
Motif DE_72h DE_72h-HOXC4_MA1504.2 6 bp overlap
HOXD4 3 datasets
Motif DE_36h DE_36h-HOXD4_MA1507.2 6 bp overlap
Motif DE_60h DE_60h-HOXD4_MA1507.2 6 bp overlap
Motif DE_72h DE_72h-HOXD4_MA1507.2 6 bp overlap
Hmga1 2 datasets
Motif DE_36h DE_36h-Hmga1_MA2124.1 8 bp overlap
Motif DE_72h DE_72h-Hmga1_MA2124.1 8 bp overlap
JUN 1 dataset
ChIP DE_D2 S02-DE-d2-JUN-exp1 283 bp overlap
MEIS1 3 datasets
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
MYC 1 dataset
ChIP P493-6_MST-312 GSE77061.MYC.P493-6_MST-312 131 bp overlap
NCOR1 1 dataset
ChIP LS180_125 GSE39277.NCOR1.LS180_125 146 bp overlap
NOTCH3 1 dataset
ChIP TALL-1_DMSO GSE104261.NOTCH3.TALL-1_DMSO 179 bp overlap
PAX3-FOXO1 1 dataset
ChIP RH4 GSE140115.PAX3-FOXO1.RH4 253 bp overlap
PDX1 1 dataset
ChIP hiPSC GSE125768.PDX1.hiPSC 185 bp overlap
PHOX2B 3 datasets
Motif DE_48h DE_48h-PHOX2B_MA0681.3 12 bp overlap
Motif DE_60h DE_60h-PHOX2B_MA0681.3 12 bp overlap
Motif DE_72h DE_72h-PHOX2B_MA0681.3 12 bp overlap
POU4F1 2 datasets
Motif DE_36h DE_36h-POU4F1_MA0790.2 12 bp overlap
Motif DE_72h DE_72h-POU4F1_MA0790.2 12 bp overlap
POU4F2 2 datasets
Motif DE_36h DE_36h-POU4F2_MA0683.2 15 bp overlap
Motif DE_72h DE_72h-POU4F2_MA0683.2 15 bp overlap
POU4F3 2 datasets
Motif DE_36h DE_36h-POU4F3_MA0791.2 12 bp overlap
Motif DE_72h DE_72h-POU4F3_MA0791.2 12 bp overlap
Prdm15 1 dataset
Motif DE_72h DE_72h-Prdm15_MA1616.2 11 bp overlap
REST 1 dataset
ChIP GP5D_SIRAD21 GSE51234.REST.GP5D_SIRAD21 185 bp overlap
RNF2 1 dataset
ChIP K-562 ENCSR820GND.RNF2.K-562 217 bp overlap
RORB 3 datasets
Motif DE_48h DE_48h-RORB_MA1150.2 10 bp overlap
Motif DE_60h DE_60h-RORB_MA1150.2 10 bp overlap
Motif DE_72h DE_72h-RORB_MA1150.2 10 bp overlap
RUNX3 3 datasets
Motif DE_48h DE_48h-RUNX3_MA0684.3 8 bp overlap
Motif DE_60h DE_60h-RUNX3_MA0684.3 8 bp overlap
Motif DE_72h DE_72h-RUNX3_MA0684.3 8 bp overlap
SIN3A 1 dataset
ChIP HUVEC-C GSE103245.SIN3A.HUVEC-C 162 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 440 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 533 bp overlap
SMAD2_3 3 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 277 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 505 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 473 bp overlap
SOX10 2 datasets
Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap
Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 316 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 738 bp overlap
SPI1 1 dataset
ChIP macrophage_IFNG GSE47188.SPI1.macrophage_IFNG 297 bp overlap
STAT1::STAT2 2 datasets
Motif DE_60h DE_60h-STAT1STAT2_MA0517.2 13 bp overlap
Motif DE_72h DE_72h-STAT1STAT2_MA0517.2 13 bp overlap
Sox1 2 datasets
Motif DE_36h DE_36h-Sox1_MA0870.1 15 bp overlap
Motif DE_72h DE_72h-Sox1_MA0870.1 15 bp overlap
Spz1 3 datasets
Motif DE_48h DE_48h-Spz1_MA0111.1 11 bp overlap
Motif DE_60h DE_60h-Spz1_MA0111.1 11 bp overlap
Motif DE_72h DE_72h-Spz1_MA0111.1 11 bp overlap
Stat2 2 datasets
Motif DE_60h DE_60h-Stat2_MA1623.2 10 bp overlap
Motif DE_72h DE_72h-Stat2_MA1623.2 10 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 186 bp overlap
TCF7L2 3 datasets
Motif DE_48h DE_48h-TCF7L2_MA0523.2 9 bp overlap
Motif DE_60h DE_60h-TCF7L2_MA0523.2 9 bp overlap
Motif DE_72h DE_72h-TCF7L2_MA0523.2 9 bp overlap
TFAP2A 3 datasets
Motif DE_48h DE_48h-TFAP2A_MA0003.5 9 bp overlap
Motif DE_60h DE_60h-TFAP2A_MA0003.5 9 bp overlap
Motif DE_72h DE_72h-TFAP2A_MA0003.5 9 bp overlap
TFAP2C 3 datasets
Motif DE_48h DE_48h-TFAP2C_MA0814.3 9 bp overlap
Motif DE_60h DE_60h-TFAP2C_MA0814.3 9 bp overlap
Motif DE_72h DE_72h-TFAP2C_MA0814.3 9 bp overlap
TRIM25 1 dataset
ChIP MDA-MB-231 GSE79588.TRIM25.MDA-MB-231 249 bp overlap
VENTX 3 datasets
Motif DE_48h DE_48h-VENTX_MA0724.1 9 bp overlap
Motif DE_60h DE_60h-VENTX_MA0724.1 9 bp overlap
Motif DE_72h DE_72h-VENTX_MA0724.1 9 bp overlap
ZBTB12 1 dataset
Motif DE_72h DE_72h-ZBTB12_MA1649.2 7 bp overlap
ZBTB7C 2 datasets
Motif DE_60h DE_60h-ZBTB7C_MA0695.2 8 bp overlap
Motif DE_72h DE_72h-ZBTB7C_MA0695.2 8 bp overlap
ZIM3 2 datasets
Motif DE_60h DE_60h-ZIM3_MA1709.2 11 bp overlap
Motif DE_72h DE_72h-ZIM3_MA1709.2 11 bp overlap
ZNF317 1 dataset
ChIP HEK293 GSE76494.ZNF317.HEK293 152 bp overlap
ZNF331 3 datasets
Motif DE_48h DE_48h-ZNF331_MA1726.2 10 bp overlap
Motif DE_60h DE_60h-ZNF331_MA1726.2 10 bp overlap
Motif DE_72h DE_72h-ZNF331_MA1726.2 10 bp overlap
ZNF766 2 datasets
Motif DE_60h DE_60h-ZNF766_MA2098.1 9 bp overlap
Motif DE_72h DE_72h-ZNF766_MA2098.1 9 bp overlap
Zfp335 3 datasets
Motif DE_48h DE_48h-Zfp335_MA2002.2 7 bp overlap
Motif DE_60h DE_60h-Zfp335_MA2002.2 7 bp overlap
Motif DE_72h DE_72h-Zfp335_MA2002.2 7 bp overlap
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