chr4 : 86,476,717 – 86,477,944
1,227 bp 85 TFs 2 linked genes
This 1.2 kb open chromatin element is linked to MAPK10 and PTPN13 and is bound by 85 transcription factors.
Linked Genes
2 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
MAPK10 116.6 kb Distal Multiome
PTPN13 116.9 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr4:86,471,717 – 86,482,944
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
85 transcription factors
Source
Cell type
ATF4 3 datasets
Motif DE_36h DE_36h-ATF4_MA0833.3 10 bp overlap
Motif DE_60h DE_60h-ATF4_MA0833.3 10 bp overlap
Motif DE_72h DE_72h-ATF4_MA0833.3 10 bp overlap
Ahr::Arnt 2 datasets
Motif DE_36h DE_36h-AhrArnt_MA0006.2 5 bp overlap
Motif DE_48h DE_48h-AhrArnt_MA0006.2 5 bp overlap
Arid3a 2 datasets
Motif DE_36h DE_36h-Arid3a_MA0151.1 6 bp overlap
Motif DE_48h DE_48h-Arid3a_MA0151.1 6 bp overlap
BCL6B 2 datasets
Motif DE_36h DE_36h-BCL6B_MA0731.1 17 bp overlap
Motif DE_48h DE_48h-BCL6B_MA0731.1 17 bp overlap
BHLHE22 1 dataset
Motif DE_72h DE_72h-BHLHE22_MA1635.2 6 bp overlap
Bcl11B 4 datasets
Motif DE_36h DE_36h-Bcl11B_MA1989.2 9 bp overlap
Motif DE_48h DE_48h-Bcl11B_MA1989.2 9 bp overlap
Motif DE_60h DE_60h-Bcl11B_MA1989.2 9 bp overlap
Motif DE_72h DE_72h-Bcl11B_MA1989.2 9 bp overlap
CEBPG 3 datasets
Motif DE_36h DE_36h-CEBPG_MA1636.2 10 bp overlap
Motif DE_60h DE_60h-CEBPG_MA1636.2 10 bp overlap
Motif DE_72h DE_72h-CEBPG_MA1636.2 10 bp overlap
CTCF 3 datasets
Motif DE_36h DE_36h-CTCF_MA1929.2 31 bp overlap
Motif DE_60h DE_60h-CTCF_MA1929.2 31 bp overlap
Motif DE_72h DE_72h-CTCF_MA1929.2 31 bp overlap
CUX1 2 datasets
Motif DE_36h DE_36h-CUX1_MA0754.3 9 bp overlap
Motif DE_60h DE_60h-CUX1_MA0754.3 9 bp overlap
CUX2 2 datasets
Motif DE_36h DE_36h-CUX2_MA0755.2 9 bp overlap
Motif DE_60h DE_60h-CUX2_MA0755.2 9 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF093OYK 103 bp overlap
Crx 2 datasets
Motif DE_36h DE_36h-Crx_MA0467.3 6 bp overlap
Motif DE_48h DE_48h-Crx_MA0467.3 6 bp overlap
DMRTA2 1 dataset
Motif DE_36h DE_36h-DMRTA2_MA1478.2 6 bp overlap
DUX4 5 datasets
Motif DE_24h DE_24h-DUX4_MA0468.1 11 bp overlap
Motif DE_36h DE_36h-DUX4_MA0468.1 11 bp overlap
Motif DE_48h DE_48h-DUX4_MA0468.1 11 bp overlap
Motif DE_60h DE_60h-DUX4_MA0468.1 11 bp overlap
Motif DE_72h DE_72h-DUX4_MA0468.1 11 bp overlap
DUXA 1 dataset
Motif DE_36h DE_36h-DUXA_MA0884.2 13 bp overlap
Dmbx1 2 datasets
Motif DE_36h DE_36h-Dmbx1_MA0883.2 10 bp overlap
Motif DE_48h DE_48h-Dmbx1_MA0883.2 10 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 788 bp overlap
ChIP DE DE-FOXA2-2 863 bp overlap
GATA4 2 datasets
ChIP DE DE-GATA4-1 942 bp overlap
ChIP DE DE-GATA4-2 991 bp overlap
GATA6 8 datasets
ChIP DE DE-GATA6-1 1036 bp overlap
ChIP DE DE-GATA6-2 60 bp overlap
ChIP DE DE-GATA6-2 1037 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 836 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 984 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 956 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 940 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 262 bp overlap
GLIS3 3 datasets
Motif DE_36h DE_36h-GLIS3_MA0737.1 14 bp overlap
Motif DE_60h DE_60h-GLIS3_MA0737.1 14 bp overlap
Motif DE_72h DE_72h-GLIS3_MA0737.1 14 bp overlap
GRHL2 1 dataset
Motif DE_36h DE_36h-GRHL2_MA1105.3 8 bp overlap
GSC 2 datasets
Motif DE_36h DE_36h-GSC_MA0648.2 6 bp overlap
Motif DE_48h DE_48h-GSC_MA0648.2 6 bp overlap
GSC2 2 datasets
Motif DE_36h DE_36h-GSC2_MA0891.2 6 bp overlap
Motif DE_48h DE_48h-GSC2_MA0891.2 6 bp overlap
HAND2 3 datasets
Motif DE_36h DE_36h-HAND2_MA1638.2 6 bp overlap
Motif DE_60h DE_60h-HAND2_MA1638.2 6 bp overlap
Motif DE_72h DE_72h-HAND2_MA1638.2 6 bp overlap
HMBOX1 1 dataset
Motif DE_36h DE_36h-HMBOX1_MA0895.2 7 bp overlap
HOXB4 5 datasets
Motif DE_24h DE_24h-HOXB4_MA1499.2 6 bp overlap
Motif DE_36h DE_36h-HOXB4_MA1499.2 6 bp overlap
Motif DE_48h DE_48h-HOXB4_MA1499.2 6 bp overlap
Motif DE_60h DE_60h-HOXB4_MA1499.2 6 bp overlap
Motif DE_72h DE_72h-HOXB4_MA1499.2 6 bp overlap
HOXC4 5 datasets
Motif DE_24h DE_24h-HOXC4_MA1504.2 6 bp overlap
Motif DE_36h DE_36h-HOXC4_MA1504.2 6 bp overlap
Motif DE_48h DE_48h-HOXC4_MA1504.2 6 bp overlap
Motif DE_60h DE_60h-HOXC4_MA1504.2 6 bp overlap
Motif DE_72h DE_72h-HOXC4_MA1504.2 6 bp overlap
HOXD4 5 datasets
Motif DE_24h DE_24h-HOXD4_MA1507.2 6 bp overlap
Motif DE_36h DE_36h-HOXD4_MA1507.2 6 bp overlap
Motif DE_48h DE_48h-HOXD4_MA1507.2 6 bp overlap
Motif DE_60h DE_60h-HOXD4_MA1507.2 6 bp overlap
Motif DE_72h DE_72h-HOXD4_MA1507.2 6 bp overlap
Hnf1A 3 datasets
Motif DE_36h DE_36h-Hnf1A_MA1991.2 10 bp overlap
Motif DE_60h DE_60h-Hnf1A_MA1991.2 10 bp overlap
Motif DE_72h DE_72h-Hnf1A_MA1991.2 10 bp overlap
JUN 1 dataset
ChIP DE_D1 S40-DE-d1-JUN-exp2 424 bp overlap
MEIS1 1 dataset
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
MGA::EVX1 3 datasets
Motif DE_36h DE_36h-MGAEVX1_MA1960.2 11 bp overlap
Motif DE_60h DE_60h-MGAEVX1_MA1960.2 11 bp overlap
Motif DE_72h DE_72h-MGAEVX1_MA1960.2 11 bp overlap
NEUROD1 3 datasets
Motif DE_36h DE_36h-NEUROD1_MA1109.2 8 bp overlap
Motif DE_60h DE_60h-NEUROD1_MA1109.2 8 bp overlap
Motif DE_72h DE_72h-NEUROD1_MA1109.2 8 bp overlap
NHLH1 1 dataset
Motif DE_72h DE_72h-NHLH1_MA0048.3 9 bp overlap
NR2C2 2 datasets
Motif DE_36h DE_36h-NR2C2_MA0504.2 14 bp overlap
Motif DE_60h DE_60h-NR2C2_MA0504.2 14 bp overlap
NR2F1 4 datasets
Motif DE_36h DE_36h-NR2F1_MA1537.2 13 bp overlap
Motif DE_48h DE_48h-NR2F1_MA1537.2 13 bp overlap
Motif DE_60h DE_60h-NR2F1_MA1537.2 13 bp overlap
Motif DE_72h DE_72h-NR2F1_MA1537.2 13 bp overlap
Neurod2 4 datasets
Motif DE_36h DE_36h-Neurod2_MA0668.3 8 bp overlap
Motif DE_60h DE_60h-Neurod2_MA0668.3 8 bp overlap
Motif DE_72h DE_72h-Neurod2_MA0668.3 8 bp overlap
Motif DE_72h DE_72h-Neurod2_MA1993.2 6 bp overlap
ONECUT1 2 datasets
Motif DE_36h DE_36h-ONECUT1_MA0679.3 9 bp overlap
Motif DE_60h DE_60h-ONECUT1_MA0679.3 9 bp overlap
ONECUT2 2 datasets
Motif DE_36h DE_36h-ONECUT2_MA0756.3 8 bp overlap
Motif DE_60h DE_60h-ONECUT2_MA0756.3 8 bp overlap
ONECUT3 2 datasets
Motif DE_36h DE_36h-ONECUT3_MA0757.2 12 bp overlap
Motif DE_60h DE_60h-ONECUT3_MA0757.2 12 bp overlap
OSR2 2 datasets
Motif DE_36h DE_36h-OSR2_MA1646.2 8 bp overlap
Motif DE_60h DE_60h-OSR2_MA1646.2 8 bp overlap
OTX1 2 datasets
Motif DE_36h DE_36h-OTX1_MA0711.2 6 bp overlap
Motif DE_48h DE_48h-OTX1_MA0711.2 6 bp overlap
Olig2 1 dataset
Motif DE_72h DE_72h-Olig2_MA1997.2 6 bp overlap
PHOX2A 1 dataset
Motif DE_36h DE_36h-PHOX2A_MA0713.1 11 bp overlap
PHOX2B 1 dataset
Motif DE_36h DE_36h-PHOX2B_MA0681.3 12 bp overlap
PITX1 2 datasets
Motif DE_36h DE_36h-PITX1_MA0682.3 6 bp overlap
Motif DE_48h DE_48h-PITX1_MA0682.3 6 bp overlap
PITX2 2 datasets
Motif DE_36h DE_36h-PITX2_MA1547.2 8 bp overlap
Motif DE_48h DE_48h-PITX2_MA1547.2 8 bp overlap
PITX3 2 datasets
Motif DE_36h DE_36h-PITX3_MA0714.2 6 bp overlap
Motif DE_48h DE_48h-PITX3_MA0714.2 6 bp overlap
POU6F1 5 datasets
Motif DE_24h DE_24h-POU6F1_MA1549.2 7 bp overlap
Motif DE_36h DE_36h-POU6F1_MA1549.2 7 bp overlap
Motif DE_48h DE_48h-POU6F1_MA1549.2 7 bp overlap
Motif DE_60h DE_60h-POU6F1_MA1549.2 7 bp overlap
Motif DE_72h DE_72h-POU6F1_MA1549.2 7 bp overlap
POU6F2 5 datasets
Motif DE_24h DE_24h-POU6F2_MA0793.2 9 bp overlap
Motif DE_36h DE_36h-POU6F2_MA0793.2 9 bp overlap
Motif DE_48h DE_48h-POU6F2_MA0793.2 9 bp overlap
Motif DE_60h DE_60h-POU6F2_MA0793.2 9 bp overlap
Motif DE_72h DE_72h-POU6F2_MA0793.2 9 bp overlap
PPARA::RXRA 4 datasets
Motif DE_36h DE_36h-PPARARXRA_MA1148.2 17 bp overlap
Motif DE_48h DE_48h-PPARARXRA_MA1148.2 17 bp overlap
Motif DE_60h DE_60h-PPARARXRA_MA1148.2 17 bp overlap
Motif DE_72h DE_72h-PPARARXRA_MA1148.2 17 bp overlap
PPARD 2 datasets
Motif DE_36h DE_36h-PPARD_MA1550.2 14 bp overlap
Motif DE_60h DE_60h-PPARD_MA1550.2 14 bp overlap
PRDM9 6 datasets
Motif DE_36h DE_36h-PRDM9_MA1723.2 20 bp overlap
Motif DE_36h DE_36h-PRDM9_MA1723.2 20 bp overlap
Motif DE_60h DE_60h-PRDM9_MA1723.2 20 bp overlap
Motif DE_60h DE_60h-PRDM9_MA1723.2 20 bp overlap
Motif DE_72h DE_72h-PRDM9_MA1723.2 20 bp overlap
Motif DE_72h DE_72h-PRDM9_MA1723.2 20 bp overlap
PROP1 1 dataset
Motif DE_36h DE_36h-PROP1_MA0715.1 11 bp overlap
Pparg::Rxra 4 datasets
Motif DE_36h DE_36h-PpargRxra_MA0065.3 13 bp overlap
Motif DE_48h DE_48h-PpargRxra_MA0065.3 13 bp overlap
Motif DE_60h DE_60h-PpargRxra_MA0065.3 13 bp overlap
Motif DE_72h DE_72h-PpargRxra_MA0065.3 13 bp overlap
Ptf1A 3 datasets
Motif DE_36h DE_36h-Ptf1A_MA1618.2 9 bp overlap
Motif DE_60h DE_60h-Ptf1A_MA1618.2 9 bp overlap
Motif DE_72h DE_72h-Ptf1A_MA1618.2 9 bp overlap
RBPJ 1 dataset
Motif DE_72h DE_72h-RBPJ_MA1116.2 6 bp overlap
RHOXF1 2 datasets
Motif DE_36h DE_36h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_48h DE_48h-RHOXF1_MA0719.2 6 bp overlap
RREB1 4 datasets
Motif DE_36h DE_36h-RREB1_MA0073.2 19 bp overlap
Motif DE_48h DE_48h-RREB1_MA0073.2 19 bp overlap
Motif DE_60h DE_60h-RREB1_MA0073.2 19 bp overlap
Motif DE_72h DE_72h-RREB1_MA0073.2 19 bp overlap
Rhox11 1 dataset
Motif DE_36h DE_36h-Rhox11_MA0629.2 9 bp overlap
Runx1 4 datasets
Motif DE_36h DE_36h-Runx1_MA0002.3 9 bp overlap
Motif DE_48h DE_48h-Runx1_MA0002.3 9 bp overlap
Motif DE_60h DE_60h-Runx1_MA0002.3 9 bp overlap
Motif DE_72h DE_72h-Runx1_MA0002.3 9 bp overlap
SMAD2_3 3 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 268 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 614 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 252 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 294 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 814 bp overlap
SP5 3 datasets
Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap
Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap
Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap
SPIB 3 datasets
Motif DE_36h DE_36h-SPIB_MA0081.3 13 bp overlap
Motif DE_60h DE_60h-SPIB_MA0081.3 13 bp overlap
Motif DE_72h DE_72h-SPIB_MA0081.3 13 bp overlap
STAT3 1 dataset
Motif DE_72h DE_72h-STAT3_MA0144.3 9 bp overlap
TBX19 1 dataset
Motif DE_36h DE_36h-TBX19_MA0804.2 17 bp overlap
TBX5 3 datasets
Motif DE_36h DE_36h-TBX5_MA0807.1 8 bp overlap
Motif DE_60h DE_60h-TBX5_MA0807.1 8 bp overlap
Motif DE_72h DE_72h-TBX5_MA0807.1 8 bp overlap
TCF7L2 3 datasets
Motif DE_36h DE_36h-TCF7L2_MA0523.2 9 bp overlap
Motif DE_60h DE_60h-TCF7L2_MA0523.2 9 bp overlap
Motif DE_72h DE_72h-TCF7L2_MA0523.2 9 bp overlap
THRB 4 datasets
Motif DE_36h DE_36h-THRB_MA1574.2 13 bp overlap
Motif DE_48h DE_48h-THRB_MA1574.2 13 bp overlap
Motif DE_60h DE_60h-THRB_MA1574.2 13 bp overlap
Motif DE_72h DE_72h-THRB_MA1574.2 13 bp overlap
TP73 1 dataset
Motif DE_36h DE_36h-TP73_MA0861.2 16 bp overlap
Tcf12 1 dataset
Motif DE_72h DE_72h-Tcf12_MA0521.3 6 bp overlap
Twist2 1 dataset
Motif DE_72h DE_72h-Twist2_MA0633.3 6 bp overlap
ZFP14 1 dataset
Motif DE_72h DE_72h-ZFP14_MA1972.1 15 bp overlap
ZIC1 3 datasets
Motif DE_36h DE_36h-ZIC1_MA0696.1 14 bp overlap
Motif DE_60h DE_60h-ZIC1_MA0696.1 14 bp overlap
Motif DE_72h DE_72h-ZIC1_MA0696.1 14 bp overlap
ZIC5 3 datasets
Motif DE_36h DE_36h-ZIC5_MA1584.2 15 bp overlap
Motif DE_60h DE_60h-ZIC5_MA1584.2 15 bp overlap
Motif DE_72h DE_72h-ZIC5_MA1584.2 15 bp overlap
ZNF263 2 datasets
Motif DE_36h DE_36h-ZNF263_MA0528.3 7 bp overlap
Motif DE_60h DE_60h-ZNF263_MA0528.3 7 bp overlap
ZNF282 3 datasets
Motif DE_36h DE_36h-ZNF282_MA1154.2 15 bp overlap
Motif DE_48h DE_48h-ZNF282_MA1154.2 15 bp overlap
Motif DE_72h DE_72h-ZNF282_MA1154.2 15 bp overlap
ZNF320 2 datasets
Motif DE_36h DE_36h-ZNF320_MA1976.2 20 bp overlap
Motif DE_72h DE_72h-ZNF320_MA1976.2 20 bp overlap
ZNF410 3 datasets
Motif DE_36h DE_36h-ZNF410_MA0752.2 16 bp overlap
Motif DE_48h DE_48h-ZNF410_MA0752.2 16 bp overlap
Motif DE_72h DE_72h-ZNF410_MA0752.2 16 bp overlap
ZNF530 4 datasets
Motif DE_36h DE_36h-ZNF530_MA1981.2 14 bp overlap
Motif DE_48h DE_48h-ZNF530_MA1981.2 14 bp overlap
Motif DE_60h DE_60h-ZNF530_MA1981.2 14 bp overlap
Motif DE_72h DE_72h-ZNF530_MA1981.2 14 bp overlap
ZNF701 6 datasets
Motif DE_36h DE_36h-ZNF701_MA1987.2 17 bp overlap
Motif DE_36h DE_36h-ZNF701_MA1987.2 17 bp overlap
Motif DE_48h DE_48h-ZNF701_MA1987.2 17 bp overlap
Motif DE_60h DE_60h-ZNF701_MA1987.2 17 bp overlap
Motif DE_72h DE_72h-ZNF701_MA1987.2 17 bp overlap
Motif DE_72h DE_72h-ZNF701_MA1987.2 17 bp overlap
ZNF816 7 datasets
Motif DE_36h DE_36h-ZNF816_MA1719.2 15 bp overlap
Motif DE_36h DE_36h-ZNF816_MA1719.2 15 bp overlap
Motif DE_48h DE_48h-ZNF816_MA1719.2 15 bp overlap
Motif DE_48h DE_48h-ZNF816_MA1719.2 15 bp overlap
Motif DE_60h DE_60h-ZNF816_MA1719.2 15 bp overlap
Motif DE_72h DE_72h-ZNF816_MA1719.2 15 bp overlap
Motif DE_72h DE_72h-ZNF816_MA1719.2 15 bp overlap
Zfp809 1 dataset
Motif DE_72h DE_72h-Zfp809_MA2125.1 9 bp overlap
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