chr4 : 99,091,353 – 99,091,515

162 bp 50 TFs 2 linked genes

This 162 bp open chromatin element is linked to ENSG00000246090 and ADH5 and is bound by 50 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000246090		2.5 kb	Proximal	Proximity
ADH5		2.6 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

50 transcription factors

BORCS8-MEF2B,MEF2B 1 dataset

ChIP GM12878 ENCFF427QAI 162 bp overlap

BRD4 3 datasets

ChIP SUM229PE_pos_30nMtrametinib_24h GSE87418.BRD4.SUM229PE_pos_30nMtrametinib_24h 103 bp overlap

ChIP SUM229PE_pos_DMSO_24h GSE87418.BRD4.SUM229PE_pos_DMSO_24h 101 bp overlap

ChIP keratinocyte GSE140992.BRD4.keratinocyte 162 bp overlap

DPF2 1 dataset

ChIP GM12878 ENCSR509FWH.DPF2.GM12878 162 bp overlap

EBF1 2 datasets

ChIP GM12878 ENCFF167CZS 162 bp overlap

ChIP GM12878 ENCSR000DZQ.EBF1.GM12878 162 bp overlap

ELF1 2 datasets

ChIP GM12878 ENCSR841NDX.ELF1.GM12878 120 bp overlap

ChIP K562 ENCFF886KFV 78 bp overlap

ESR1 1 dataset

ChIP primary-endometrium-cancer_E1_DSG GSE114737.ESR1.primary-endometrium-cancer_E1_DSG 162 bp overlap

Elf5 1 dataset

Motif DE_12h DE_12h-Elf5_MA0136.4 8 bp overlap

GLIS1 2 datasets

ChIP HEK293 ENCFF299RSE 154 bp overlap

ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 162 bp overlap

HMBOX1 1 dataset

ChIP K-562 ENCSR757IIU.HMBOX1.K-562 162 bp overlap

HOXB13 1 dataset

ChIP prostate-cancer_PDX_189-4 GSE130408.HOXB13.prostate-cancer_PDX_189-4 59 bp overlap

IKZF1 1 dataset

ChIP GM12878 ENCFF753XDO 162 bp overlap

IKZF2 1 dataset

ChIP GM12878 ENCSR680UQE.IKZF2.GM12878 162 bp overlap

ILK 1 dataset

ChIP K-562 ENCSR648INT.ILK.K-562 84 bp overlap

KAT7 1 dataset

ChIP K562 ENCFF175ZTN 96 bp overlap

MED1 7 datasets

ChIP hMSC-TERT4_D1 GSE104537.MED1.hMSC-TERT4_D1 141 bp overlap

ChIP hMSC-TERT4_D14 GSE104537.MED1.hMSC-TERT4_D14 158 bp overlap

ChIP hMSC-TERT4_D7 GSE104537.MED1.hMSC-TERT4_D7 162 bp overlap

ChIP hMSC-TERT4_adipocyte-D14 GSE113253.MED1.hMSC-TERT4_adipocyte-D14 162 bp overlap

ChIP hMSC-TERT4_adipocyte-D7 GSE113253.MED1.hMSC-TERT4_adipocyte-D7 162 bp overlap

ChIP hMSC-TERT4_osteoblast-4H GSE113253.MED1.hMSC-TERT4_osteoblast-4H 162 bp overlap

ChIP hMSC-TERT4_osteoblast-D3 GSE113253.MED1.hMSC-TERT4_osteoblast-D3 162 bp overlap

MEF2B 1 dataset

ChIP GM12878 ENCSR177VFS.MEF2B.GM12878 162 bp overlap

MEN1 1 dataset

ChIP MCF-7 GSE85317.MEN1.MCF-7 96 bp overlap

MTA2 1 dataset

ChIP GM12878 ENCSR293QAR.MTA2.GM12878 144 bp overlap

NBN 1 dataset

ChIP K-562 ENCSR085QEV.NBN.K-562 162 bp overlap

NFATC3 1 dataset

ChIP GM12878 ENCSR437GBJ.NFATC3.GM12878 162 bp overlap

NR2C1 1 dataset

Motif DE_12h DE_12h-NR2C1_MA1535.2 6 bp overlap

NR2C2 1 dataset

Motif DE_12h DE_12h-NR2C2_MA1536.2 6 bp overlap

NR3C1 5 datasets

ChIP MCF-10A_DEX_20min GSE102355.NR3C1.MCF-10A_DEX_20min 162 bp overlap

ChIP MCF-10A_EGF_DEX_20min GSE102355.NR3C1.MCF-10A_EGF_DEX_20min 162 bp overlap

ChIP U2OS_GLUCC ERP007081.NR3C1.U2OS_GLUCC 120 bp overlap

ChIP U2OS_SHHIC5 GSE65847.NR3C1.U2OS_SHHIC5 162 bp overlap

ChIP U2OS_siHic5siNS GSE109383.NR3C1.U2OS_siHic5siNS 162 bp overlap

Nfatc2 1 dataset

Motif DE_12h DE_12h-Nfatc2_MA0152.3 8 bp overlap

Nr1H2 1 dataset

Motif DE_12h DE_12h-Nr1H2_MA1996.2 6 bp overlap

Nr1H4 1 dataset

Motif DE_12h DE_12h-Nr1H4_MA1110.3 6 bp overlap

Nr1h3 1 dataset

Motif DE_12h DE_12h-Nr1h3_MA2337.1 6 bp overlap

PGR 1 dataset

Motif DE_12h DE_12h-PGR_MA2327.1 9 bp overlap

REL 1 dataset

Motif DE_12h DE_12h-REL_MA0101.1 10 bp overlap

RELB 1 dataset

ChIP GM12878 ENCSR387QUV.RELB.GM12878 162 bp overlap

REST 1 dataset

ChIP hippocampus GSE144226.REST.hippocampus 85 bp overlap

SKIL 1 dataset

ChIP GM12878 ENCSR212YKD.SKIL.GM12878 162 bp overlap

SMAD1 1 dataset

ChIP GM12878 ENCSR813DCK.SMAD1.GM12878 121 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 60 bp overlap

SMAD3 1 dataset

Motif DE_12h DE_12h-SMAD3_MA0795.1 10 bp overlap

SMARCA2 2 datasets

ChIP NPC_K755R-siCT GSE122631.SMARCA2.NPC_K755R-siCT 72 bp overlap

ChIP NPC_R1159Q_AM GSE122631.SMARCA2.NPC_R1159Q_AM 162 bp overlap

SMARCA4 3 datasets

ChIP K-562 ENCSR587OQL.SMARCA4.K-562 162 bp overlap

ChIP NPC_K755R-siAP GSE122631.SMARCA4.NPC_K755R-siAP 106 bp overlap

ChIP endometrial-epithelial-cells_KO GSE106660.SMARCA4.endometrial-epithelial-cells_KO 162 bp overlap

SMARCA5 1 dataset

ChIP GM12878 ENCSR706YUH.SMARCA5.GM12878 162 bp overlap

SMARCC1 2 datasets

ChIP SK-N-MC GSE94275.SMARCC1.SK-N-MC 149 bp overlap

ChIP SK-N-MC_shGFP GSE94275.SMARCC1.SK-N-MC_shGFP 98 bp overlap

SPI1 9 datasets

ChIP CD34_FETAL GSE70660.SPI1.CD34_FETAL 74 bp overlap

ChIP CTV-1_FLAG_15perc GSE128835.SPI1.CTV-1_FLAG_15perc 145 bp overlap

ChIP CTV-1_delQ GSE128835.SPI1.CTV-1_delQ 79 bp overlap

ChIP GM12891 ENCSR000BIJ.SPI1.GM12891 92 bp overlap

ChIP HL-60 ENCFF645GBT 153 bp overlap

ChIP K-562 GSE70482.SPI1.K-562 128 bp overlap

ChIP K-562 ENCSR000BGW.SPI1.K-562 88 bp overlap

ChIP K-562_NABUT GSE74999.SPI1.K-562_NABUT 77 bp overlap

ChIP K562 ENCFF410ORC 123 bp overlap

STAT3 1 dataset

ChIP HepaRG_sodium-oleate GSE89157.STAT3.HepaRG_sodium-oleate 69 bp overlap

Smad4 1 dataset

Motif DE_12h DE_12h-Smad4_MA1153.2 7 bp overlap

TBX21 2 datasets

ChIP GM12878 ENCFF951HUW 162 bp overlap

ChIP GM12878 ENCSR739IHN.TBX21.GM12878 162 bp overlap

TERF1 1 dataset

ChIP LCL GSE55053.TERF1.LCL 135 bp overlap

TFAP2C 2 datasets

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 162 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 162 bp overlap

TP53 1 dataset

ChIP U2OS_NUT GSE46641.TP53.U2OS_NUT 130 bp overlap

Tfcp2l1 1 dataset

Motif DE_12h DE_12h-Tfcp2l1_MA0145.2 14 bp overlap

ZBTB7A 1 dataset

ChIP K-562 GSE103445.ZBTB7A.K-562 96 bp overlap

ZNF707 1 dataset

Motif DE_12h DE_12h-ZNF707_MA1715.1 15 bp overlap

ZNF750 1 dataset

ChIP keratinocyte_diff GSE57702.ZNF750.keratinocyte_diff 162 bp overlap