chr4 : 174,531,709 – 174,532,360
651 bp 54 TFs 2 linked genes
This 651 bp open chromatin element is linked to HPGD and ENSG00000251584 and is bound by 54 transcription factors.
Linked Genes
2 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
HPGD 9.1 kb Proximal Proximity
ENSG00000251584 9.1 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr4:174,526,709 – 174,537,360
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
54 transcription factors
Source
Cell type
ARID1B 2 datasets
ChIP K-562 ENCSR822CCM.ARID1B.K-562 310 bp overlap
ChIP K562 ENCFF938UXQ 401 bp overlap
CBFA2T3 1 dataset
ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 162 bp overlap
CHAMP1 1 dataset
ChIP K-562 ENCSR065XVO.CHAMP1.K-562 225 bp overlap
CTBP1 1 dataset
ChIP K-562 ENCSR201NQZ.CTBP1.K-562 214 bp overlap
CTCF 3 datasets
Motif DE_60h DE_60h-CTCF_MA0139.2 15 bp overlap
Motif DE_60h DE_60h-CTCF_MA1929.2 31 bp overlap
ChIP Peyer's patch ENCFF828IDE 341 bp overlap
DUX4 3 datasets
Motif DE_36h DE_36h-DUX4_MA0468.1 11 bp overlap
Motif DE_48h DE_48h-DUX4_MA0468.1 11 bp overlap
Motif DE_60h DE_60h-DUX4_MA0468.1 11 bp overlap
GATA1 3 datasets
ChIP K-562 GSE107726.GATA1.K-562 241 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 138 bp overlap
ChIP erythroblast ENCSR000EXP.GATA1.erythroblast 228 bp overlap
GATA2 3 datasets
Motif DE_36h DE_36h-GATA2_MA0036.4 7 bp overlap
Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
GATA4 10 datasets
ChIP A-549 GSE85002.GATA4.A-549 64 bp overlap
ChIP DE DE-GATA4-1 644 bp overlap
ChIP DE DE-GATA4-2 651 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
ChIP Hep-G2 GSE135714.GATA4.Hep-G2 149 bp overlap
ChIP foregut GSE117136.GATA4.foregut 505 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 422 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 326 bp overlap
GATA5 3 datasets
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
GATA6 13 datasets
ChIP AGS GSE51705.GATA6.AGS 163 bp overlap
ChIP DE DE-GATA6-1 571 bp overlap
ChIP DE DE-GATA6-2 650 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 355 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 310 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 462 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 627 bp overlap
ChIP foregut GSE117136.GATA6.foregut 533 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 285 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 295 bp overlap
Gata3 3 datasets
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
HDAC1 1 dataset
ChIP K-562 ENCSR711VWL.HDAC1.K-562 278 bp overlap
HDAC2 1 dataset
ChIP K-562 ENCSR893WSB.HDAC2.K-562 284 bp overlap
HSF1 1 dataset
ChIP MO91 GSE45852.HSF1.MO91 190 bp overlap
IKZF1 1 dataset
ChIP K-562 ENCSR395HWC.IKZF1.K-562 480 bp overlap
Irf1 1 dataset
Motif DE_60h DE_60h-Irf1_MA0050.4 11 bp overlap
JUND 3 datasets
Motif DE_36h DE_36h-JUND_MA0492.2 11 bp overlap
Motif DE_48h DE_48h-JUND_MA0492.2 11 bp overlap
Motif DE_60h DE_60h-JUND_MA0492.2 11 bp overlap
KDM1A 4 datasets
ChIP K-562 ENCSR360HRA.KDM1A.K-562 375 bp overlap
ChIP K-562 ENCSR908CMW.KDM1A.K-562 249 bp overlap
ChIP K562 ENCFF128TYE 461 bp overlap
ChIP K562 ENCFF133OLU 461 bp overlap
MAZ 1 dataset
Motif DE_60h DE_60h-MAZ_MA1522.2 8 bp overlap
MEIS1 3 datasets
Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
MYB 1 dataset
ChIP DU528 GSE94000.MYB.DU528 305 bp overlap
Mecom 3 datasets
Motif DE_36h DE_36h-Mecom_MA0029.2 11 bp overlap
Motif DE_48h DE_48h-Mecom_MA0029.2 11 bp overlap
Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap
NANOG 1 dataset
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 267 bp overlap
NFE2 1 dataset
ChIP ProEs GSE59087.NFE2.ProEs 96 bp overlap
NFYA 3 datasets
Motif DE_36h DE_36h-NFYA_MA0060.4 8 bp overlap
Motif DE_48h DE_48h-NFYA_MA0060.4 8 bp overlap
Motif DE_60h DE_60h-NFYA_MA0060.4 8 bp overlap
NFYB 4 datasets
Motif DE_36h DE_36h-NFYB_MA0502.3 9 bp overlap
Motif DE_48h DE_48h-NFYB_MA0502.3 9 bp overlap
Motif DE_60h DE_60h-NFYB_MA0502.3 9 bp overlap
ChIP K-562 ENCSR000EGQ.NFYB.K-562 147 bp overlap
NFYC 3 datasets
Motif DE_36h DE_36h-NFYC_MA1644.2 7 bp overlap
Motif DE_48h DE_48h-NFYC_MA1644.2 7 bp overlap
Motif DE_60h DE_60h-NFYC_MA1644.2 7 bp overlap
Nfat5 1 dataset
Motif DE_60h DE_60h-Nfat5_MA0606.3 8 bp overlap
POU2F1::SOX2 6 datasets
Motif DE_36h DE_36h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif DE_36h DE_36h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif DE_48h DE_48h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif DE_48h DE_48h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif DE_60h DE_60h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif DE_60h DE_60h-POU2F1SOX2_MA1962.1 17 bp overlap
POU5F1 1 dataset
ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 229 bp overlap
Pou5f1::Sox2 3 datasets
Motif DE_36h DE_36h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif DE_48h DE_48h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif DE_60h DE_60h-Pou5f1Sox2_MA0142.1 15 bp overlap
Prdm4 3 datasets
Motif DE_36h DE_36h-Prdm4_MA1647.3 11 bp overlap
Motif DE_48h DE_48h-Prdm4_MA1647.3 11 bp overlap
Motif DE_60h DE_60h-Prdm4_MA1647.3 11 bp overlap
REST 1 dataset
ChIP K-562 ENCSR137ZMQ.REST.K-562 295 bp overlap
RORA 1 dataset
Motif DE_60h DE_60h-RORA_MA0072.2 11 bp overlap
RXRA::VDR 1 dataset
Motif DE_60h DE_60h-RXRAVDR_MA0074.1 15 bp overlap
SOX15 3 datasets
Motif DE_36h DE_36h-SOX15_MA1152.2 7 bp overlap
Motif DE_48h DE_48h-SOX15_MA1152.2 7 bp overlap
Motif DE_60h DE_60h-SOX15_MA1152.2 7 bp overlap
SOX18 3 datasets
Motif DE_36h DE_36h-SOX18_MA1563.2 8 bp overlap
Motif DE_48h DE_48h-SOX18_MA1563.2 8 bp overlap
Motif DE_60h DE_60h-SOX18_MA1563.2 8 bp overlap
SOX6 2 datasets
ChIP K-562 ENCSR788RSW.SOX6.K-562 521 bp overlap
ChIP K562 ENCFF059YCJ 437 bp overlap
SOX8 3 datasets
Motif DE_36h DE_36h-SOX8_MA0868.3 7 bp overlap
Motif DE_48h DE_48h-SOX8_MA0868.3 7 bp overlap
Motif DE_60h DE_60h-SOX8_MA0868.3 7 bp overlap
SOX9 3 datasets
Motif DE_36h DE_36h-SOX9_MA0077.2 8 bp overlap
Motif DE_48h DE_48h-SOX9_MA0077.2 8 bp overlap
Motif DE_60h DE_60h-SOX9_MA0077.2 8 bp overlap
SRY 3 datasets
Motif DE_36h DE_36h-SRY_MA0084.2 7 bp overlap
Motif DE_48h DE_48h-SRY_MA0084.2 7 bp overlap
Motif DE_60h DE_60h-SRY_MA0084.2 7 bp overlap
STAT1::STAT2 3 datasets
Motif DE_36h DE_36h-STAT1STAT2_MA0517.2 13 bp overlap
Motif DE_48h DE_48h-STAT1STAT2_MA0517.2 13 bp overlap
Motif DE_60h DE_60h-STAT1STAT2_MA0517.2 13 bp overlap
Sox17 3 datasets
Motif DE_36h DE_36h-Sox17_MA0078.3 10 bp overlap
Motif DE_48h DE_48h-Sox17_MA0078.3 10 bp overlap
Motif DE_60h DE_60h-Sox17_MA0078.3 10 bp overlap
Sox5 3 datasets
Motif DE_36h DE_36h-Sox5_MA0087.3 8 bp overlap
Motif DE_48h DE_48h-Sox5_MA0087.3 8 bp overlap
Motif DE_60h DE_60h-Sox5_MA0087.3 8 bp overlap
Sox7 3 datasets
Motif DE_36h DE_36h-Sox7_MA2095.1 10 bp overlap
Motif DE_48h DE_48h-Sox7_MA2095.1 10 bp overlap
Motif DE_60h DE_60h-Sox7_MA2095.1 10 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 117 bp overlap
TAL1 2 datasets
ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 195 bp overlap
ChIP ProEs GSE59087.TAL1.ProEs 80 bp overlap
TCF21 1 dataset
ChIP HCASMC GSE124011.TCF21.HCASMC 211 bp overlap
TRPS1 3 datasets
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
ZEB2 3 datasets
ChIP K-562 ENCSR322CFO.ZEB2.K-562 288 bp overlap
ChIP K-562 ENCSR004GKA.ZEB2.K-562 348 bp overlap
ChIP K562 ENCFF795CMH 477 bp overlap
ZNF148 1 dataset
Motif DE_60h DE_60h-ZNF148_MA1653.2 10 bp overlap
ZNF677 3 datasets
Motif DE_36h DE_36h-ZNF677_MA2101.1 12 bp overlap
Motif DE_48h DE_48h-ZNF677_MA2101.1 12 bp overlap
Motif DE_60h DE_60h-ZNF677_MA2101.1 12 bp overlap
ZSCAN4 1 dataset
Motif DE_60h DE_60h-ZSCAN4_MA1155.1 15 bp overlap
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