chr5 : 122,306,349 – 122,307,037

688 bp 89 TFs 2 linked genes

This 688 bp open chromatin element is linked to ENSG00000272139 and SNCAIP and is bound by 89 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000272139		4.6 kb	Proximal	Proximity
SNCAIP		5.2 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

89 transcription factors

Arid3a 1 dataset

Motif DE_48h DE_48h-Arid3a_MA0151.1 6 bp overlap

BCL6 1 dataset

ChIP OCI-Ly1_UV GSE103125.BCL6.OCI-Ly1_UV 219 bp overlap

CDK9-HEXIM1 1 dataset

ChIP A-375 GSE68047.CDK9-HEXIM1.A-375 144 bp overlap

CEBPA 1 dataset

ChIP THP-1_EtOH_2h GSE124032.CEBPA.THP-1_EtOH_2h 144 bp overlap

EHF 2 datasets

Motif DE_48h DE_48h-EHF_MA0598.4 9 bp overlap

ChIP RWPE-1 GSE114241.EHF.RWPE-1 260 bp overlap

ELF3 4 datasets

Motif DE_48h DE_48h-ELF3_MA0640.3 9 bp overlap

ChIP PDAC GSE64557.ELF3.PDAC 334 bp overlap

ChIP PDAC_KOKLF5 GSE64557.ELF3.PDAC_KOKLF5 562 bp overlap

ChIP PDAC_SHCTR GSE64557.ELF3.PDAC_SHCTR 527 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 303 bp overlap

ERF::HOXB13 1 dataset

Motif DE_48h DE_48h-ERFHOXB13_MA1937.2 13 bp overlap

ERG 2 datasets

ChIP K-562_DOX GSE23730.ERG.K-562_DOX 230 bp overlap

ChIP TSU-1621MT_ATRA GSE60477.ERG.TSU-1621MT_ATRA 300 bp overlap

ESRRA 1 dataset

Motif DE_48h DE_48h-ESRRA_MA0592.4 9 bp overlap

ETV2 1 dataset

Motif DE_48h DE_48h-ETV2_MA0762.2 9 bp overlap

ETV2::DRGX 1 dataset

Motif DE_48h DE_48h-ETV2DRGX_MA1940.2 12 bp overlap

ETV5::DRGX 1 dataset

Motif DE_48h DE_48h-ETV5DRGX_MA1944.2 12 bp overlap

ETV7 1 dataset

Motif DE_48h DE_48h-ETV7_MA1708.2 9 bp overlap

Erg 1 dataset

Motif DE_48h DE_48h-Erg_MA0474.4 10 bp overlap

FOS 1 dataset

ChIP MCF-10A ENCSR000DON.FOS.MCF-10A 201 bp overlap

FOXA1 5 datasets

Motif DE_48h DE_48h-FOXA1_MA0148.5 8 bp overlap

ChIP MCF-7_E2 GSE60270.FOXA1.MCF-7_E2 373 bp overlap

ChIP PDAC_KOKLF5 GSE64557.FOXA1.PDAC_KOKLF5 388 bp overlap

ChIP T-47D_JC4743 GSE126004.FOXA1.T-47D_JC4743 197 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 343 bp overlap

FOXA2 8 datasets

ChIP CFPAC-1 GSE119930.FOXA2.CFPAC-1 370 bp overlap

ChIP CFPAC-1_EV GSE119930.FOXA2.CFPAC-1_EV 383 bp overlap

ChIP CFPAC-1_HNF1B-KO GSE119930.FOXA2.CFPAC-1_HNF1B-KO 243 bp overlap

ChIP Caco-2 GSE66218.FOXA2.Caco-2 262 bp overlap

ChIP DE DE-FOXA2-1 611 bp overlap

ChIP DE DE-FOXA2-2 688 bp overlap

ChIP liver_CARN1618 ERP008682.FOXA2.liver_CARN1618 362 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 436 bp overlap

FOXF2 1 dataset

Motif DE_48h DE_48h-FOXF2_MA0030.2 9 bp overlap

FOXG1 1 dataset

Motif DE_48h DE_48h-FOXG1_MA0613.1 8 bp overlap

FOXK1 1 dataset

Motif DE_48h DE_48h-FOXK1_MA0852.3 7 bp overlap

FOXK2 1 dataset

Motif DE_48h DE_48h-FOXK2_MA1103.3 7 bp overlap

FOXL1 1 dataset

Motif DE_48h DE_48h-FOXL1_MA0033.2 7 bp overlap

FOXO4 1 dataset

Motif DE_48h DE_48h-FOXO4_MA0848.1 7 bp overlap

FOXO6 1 dataset

Motif DE_48h DE_48h-FOXO6_MA0849.1 7 bp overlap

FOXP3 1 dataset

Motif DE_48h DE_48h-FOXP3_MA0850.1 7 bp overlap

Foxf1 1 dataset

Motif DE_48h DE_48h-Foxf1_MA1606.2 7 bp overlap

Foxj2 1 dataset

Motif DE_48h DE_48h-Foxj2_MA0614.1 8 bp overlap

Foxj3 1 dataset

Motif DE_48h DE_48h-Foxj3_MA0851.2 9 bp overlap

Foxo1 1 dataset

Motif DE_48h DE_48h-Foxo1_MA0480.3 7 bp overlap

Foxo3 1 dataset

Motif DE_48h DE_48h-Foxo3_MA0157.4 7 bp overlap

GABPA 1 dataset

Motif DE_48h DE_48h-GABPA_MA0062.4 10 bp overlap

GATA2 1 dataset

ChIP primary-endometrial-stromal-cell_IVD_P2 GSE145673.GATA2.primary-endometrial-stromal-cell_IVD_P2 350 bp overlap

GATA4 7 datasets

ChIP DE DE-GATA4-1 440 bp overlap

ChIP DE DE-GATA4-2 603 bp overlap

Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap

ChIP Hep-G2 GSE135714.GATA4.Hep-G2 287 bp overlap

ChIP foregut GSE117136.GATA4.foregut 507 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 587 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 563 bp overlap

GATA5 1 dataset

Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap

GATA6 10 datasets

ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 203 bp overlap

ChIP DE DE-GATA6-1 391 bp overlap

ChIP DE DE-GATA6-2 518 bp overlap

Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 503 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 276 bp overlap

ChIP foregut GSE117136.GATA6.foregut 455 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 658 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 497 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 511 bp overlap

Gata3 1 dataset

Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap

Gfi1B 1 dataset

Motif DE_48h DE_48h-Gfi1B_MA0483.2 10 bp overlap

HMBOX1 1 dataset

ChIP K-562 ENCSR757IIU.HMBOX1.K-562 146 bp overlap

HNF1A 1 dataset

Motif DE_48h DE_48h-HNF1A_MA0046.3 13 bp overlap

HNF1B 1 dataset

Motif DE_48h DE_48h-HNF1B_MA0153.2 13 bp overlap

HSF2 1 dataset

Motif DE_48h DE_48h-HSF2_MA0770.1 13 bp overlap

IKZF1 1 dataset

Motif DE_48h DE_48h-IKZF1_MA1508.2 8 bp overlap

Irf1 1 dataset

Motif DE_48h DE_48h-Irf1_MA0050.4 11 bp overlap

KDM1A 2 datasets

ChIP pancreatic-progenitor_PP1 GSE104840.KDM1A.pancreatic-progenitor_PP1 266 bp overlap

ChIP pancreatic-progenitor_PP2-KDM1A-inh GSE104840.KDM1A.pancreatic-progenitor_PP2-KDM1A-inh 234 bp overlap

LMO2 1 dataset

ChIP TSU-1621MT GSE60477.LMO2.TSU-1621MT 210 bp overlap

MEF2C 1 dataset

Motif DE_48h DE_48h-MEF2C_MA0497.2 11 bp overlap

MYB 1 dataset

ChIP Loucy GSE94000.MYB.Loucy 221 bp overlap

Mecom 3 datasets

Motif DE_48h DE_48h-Mecom_MA0029.2 11 bp overlap

NR2C1 1 dataset

Motif DE_48h DE_48h-NR2C1_MA1535.2 6 bp overlap

NR2C2 1 dataset

Motif DE_48h DE_48h-NR2C2_MA1536.2 6 bp overlap

NR3C1 2 datasets

ChIP HCC70 GSE152203.NR3C1.HCC70 183 bp overlap

ChIP SUM159PT GSE152203.NR3C1.SUM159PT 317 bp overlap

NRL 1 dataset

Motif DE_48h DE_48h-NRL_MA0842.3 12 bp overlap

Nr1H2 1 dataset

Motif DE_48h DE_48h-Nr1H2_MA1996.2 6 bp overlap

Nr1H4 1 dataset

Motif DE_48h DE_48h-Nr1H4_MA1110.3 6 bp overlap

Nr1h3 1 dataset

Motif DE_48h DE_48h-Nr1h3_MA2337.1 6 bp overlap

ONECUT1 1 dataset

ChIP pancreatic-progenitor_PP1 GSE104840.ONECUT1.pancreatic-progenitor_PP1 346 bp overlap

PBX1 1 dataset

Motif DE_48h DE_48h-PBX1_MA0070.2 9 bp overlap

PDX1 4 datasets

ChIP hESC GSE58685.PDX1.hESC 263 bp overlap

ChIP hiPSC GSE125768.PDX1.hiPSC 341 bp overlap

ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 400 bp overlap

ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 540 bp overlap

PKNOX1 1 dataset

ChIP HEK293T ENCSR233FAG.PKNOX1.HEK293T 200 bp overlap

PPARD 1 dataset

Motif DE_48h DE_48h-PPARD_MA1550.2 14 bp overlap

PSIP1 1 dataset

ChIP T-REx-293 GSE117155.PSIP1.T-REx-293 220 bp overlap

Pgr 1 dataset

Motif DE_48h DE_48h-Pgr_MA2323.1 17 bp overlap

Prdm4 1 dataset

Motif DE_48h DE_48h-Prdm4_MA1647.3 11 bp overlap

RBPJ 1 dataset

Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap

RELA 2 datasets

ChIP FaDu_LPS GSE132018.RELA.FaDu_LPS 206 bp overlap

ChIP aortic-endothelial-cell_IL1B_D39 GSE139377.RELA.aortic-endothelial-cell_IL1B_D39 222 bp overlap

RNF2 1 dataset

ChIP ME-1_KD GSE128771.RNF2.ME-1_KD 362 bp overlap

RORA 1 dataset

Motif DE_48h DE_48h-RORA_MA0071.1 10 bp overlap

RUNX1 5 datasets

ChIP ME-1 GSE46044.RUNX1.ME-1 213 bp overlap

ChIP ME-1 GSE117138.RUNX1.ME-1 293 bp overlap

ChIP ME-1_CBFB-MYH11-KD GSE117138.RUNX1.ME-1_CBFB-MYH11-KD 339 bp overlap

ChIP ME-1_Con GSE128771.RUNX1.ME-1_Con 339 bp overlap

ChIP ME-1_KD GSE128771.RUNX1.ME-1_KD 293 bp overlap

SETDB1 1 dataset

ChIP U2OS ENCSR000EYD.SETDB1.U2OS 298 bp overlap

SMAD2 1 dataset

Motif DE_48h DE_48h-SMAD2_MA1964.2 6 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 452 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 281 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 298 bp overlap

SMAD4 1 dataset

ChIP Caco-2 GSE112946.SMAD4.Caco-2 249 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 276 bp overlap

SPIB 1 dataset

Motif DE_48h DE_48h-SPIB_MA0081.3 13 bp overlap

SREBF1 1 dataset

Motif DE_48h DE_48h-SREBF1_MA0829.3 10 bp overlap

STAT3 17 datasets

ChIP HCC1187 GSE152203.STAT3.HCC1187 246 bp overlap

ChIP HCC70 GSE152203.STAT3.HCC70 521 bp overlap

ChIP HCC70_EtOH GSE85579.STAT3.HCC70_EtOH 602 bp overlap

ChIP MCF-10A ENCSR000DOQ.STAT3.MCF-10A 566 bp overlap

ChIP MCF-10A ENCSR000DOZ.STAT3.MCF-10A 252 bp overlap

ChIP MCF-7_jc5840 GSE126004.STAT3.MCF-7_jc5840 346 bp overlap

ChIP MCF10A-Er-Src_EtOH GSE115597.STAT3.MCF10A-Er-Src_EtOH 189 bp overlap

ChIP MCF10A-Er-Src_TAM GSE115597.STAT3.MCF10A-Er-Src_TAM 333 bp overlap

ChIP MDA-MB-157_EtOH GSE85579.STAT3.MDA-MB-157_EtOH 319 bp overlap

ChIP MDA-MB-468_EtOH GSE85579.STAT3.MDA-MB-468_EtOH 187 bp overlap

ChIP SUM159PT GSE152203.STAT3.SUM159PT 241 bp overlap

ChIP T-47D_JC4741 GSE126004.STAT3.T-47D_JC4741 260 bp overlap

ChIP T-47D_JC4753 GSE126004.STAT3.T-47D_JC4753 237 bp overlap

ChIP T-47D_JC4757 GSE126004.STAT3.T-47D_JC4757 548 bp overlap

ChIP T-47D_JC5054 GSE126004.STAT3.T-47D_JC5054 368 bp overlap

ChIP T-47D_JC5056 GSE126004.STAT3.T-47D_JC5056 506 bp overlap

ChIP T-47D_JC5062 GSE126004.STAT3.T-47D_JC5062 448 bp overlap

Spi1 1 dataset

Motif DE_48h DE_48h-Spi1_MA0080.7 13 bp overlap

Stat2 1 dataset

Motif DE_48h DE_48h-Stat2_MA1623.2 10 bp overlap

TAL1 2 datasets

ChIP ME-1 GSE46044.TAL1.ME-1 211 bp overlap

ChIP TSU-1621MT GSE60477.TAL1.TSU-1621MT 353 bp overlap

TCF12 1 dataset

ChIP ME-1 GSE46044.TCF12.ME-1 341 bp overlap

TFEB 1 dataset

ChIP HUVEC-C GSE88894.TFEB.HUVEC-C 172 bp overlap

TRPS1 1 dataset

Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap

USF2 1 dataset

ChIP GM12878 GSE97661.USF2.GM12878 174 bp overlap

VENTX 1 dataset

Motif DE_48h DE_48h-VENTX_MA0724.1 9 bp overlap

ZNF24 1 dataset

Motif DE_48h DE_48h-ZNF24_MA1124.1 13 bp overlap

ZNF317 1 dataset

Motif DE_48h DE_48h-ZNF317_MA1593.2 8 bp overlap

ZNF677 1 dataset

Motif DE_48h DE_48h-ZNF677_MA2101.1 12 bp overlap