chr5 : 133,686,961 – 133,687,622
661 bp 66 TFs 2 linked genes
This 661 bp open chromatin element is linked to FSTL4 and C5orf15 and is bound by 66 transcription factors.
Linked Genes
2 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
FSTL4 74.9 kb Distal Multiome
C5orf15 281.2 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr5:133,681,961 – 133,692,622
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
66 transcription factors
Source
Cell type
Ahr::Arnt 3 datasets
Motif DE_36h DE_36h-AhrArnt_MA0006.2 5 bp overlap
Motif DE_48h DE_48h-AhrArnt_MA0006.2 5 bp overlap
Motif DE_72h DE_72h-AhrArnt_MA0006.2 5 bp overlap
Arid3a 1 dataset
Motif DE_36h DE_36h-Arid3a_MA0151.1 6 bp overlap
BRCA1 1 dataset
ChIP SH-EP_pWZL-MYCNwt GSE111905.BRCA1.SH-EP_pWZL-MYCNwt 95 bp overlap
BRD4 1 dataset
ChIP K-562_iBET-BD1-IFNG GSE138084.BRD4.K-562_iBET-BD1-IFNG 214 bp overlap
CBFA2T2 1 dataset
ChIP NCCIT GSE71675.CBFA2T2.NCCIT 229 bp overlap
CBFA2T3 2 datasets
ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 223 bp overlap
ChIP K562 ENCFF673OEZ 411 bp overlap
CEBPD 1 dataset
ChIP K-562 ENCSR000BVY.CEBPD.K-562 120 bp overlap
CRY1 1 dataset
ChIP U2OS GSE44236.CRY1.U2OS 201 bp overlap
CTBP1 1 dataset
ChIP K-562 ENCSR201NQZ.CTBP1.K-562 256 bp overlap
CTNNB1 1 dataset
ChIP hiPSC_D2 GSE132532.CTNNB1.hiPSC_D2 229 bp overlap
Cebpa 4 datasets
ChIP BLaER1 ENCFF031ISE 252 bp overlap
ChIP BLaER1 ENCFF274GAT 51 bp overlap
ChIP BLaER1 ENCFF460KDD 414 bp overlap
ChIP BLaER1 ENCFF844FIP 164 bp overlap
DUX4 1 dataset
Motif DE_36h DE_36h-DUX4_MA0468.1 11 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 352 bp overlap
ESR1 1 dataset
ChIP Ishikawa_siNTC-96h GSE129803.ESR1.Ishikawa_siNTC-96h 218 bp overlap
FOXA1 1 dataset
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 323 bp overlap
FOXA2 3 datasets
ChIP DE DE-FOXA2-1 461 bp overlap
ChIP DE DE-FOXA2-2 608 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 272 bp overlap
GATA1 4 datasets
ChIP CD34_ERYTH_BMP GSE29194.GATA1.CD34_ERYTH_BMP 110 bp overlap
ChIP K-562 GSE107726.GATA1.K-562 215 bp overlap
ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 272 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 241 bp overlap
GATA1::TAL1 3 datasets
Motif DE_36h DE_36h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_72h DE_72h-GATA1TAL1_MA0140.3 17 bp overlap
GATA2 3 datasets
Motif DE_36h DE_36h-GATA2_MA0036.4 7 bp overlap
Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap
ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 182 bp overlap
GATA4 7 datasets
ChIP DE DE-GATA4-1 468 bp overlap
ChIP DE DE-GATA4-2 512 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 436 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 380 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 470 bp overlap
GATA5 2 datasets
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
GATA6 17 datasets
ChIP AGS GSE51705.GATA6.AGS 230 bp overlap
ChIP DE DE-GATA6-1 513 bp overlap
ChIP DE DE-GATA6-2 661 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 449 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 429 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 475 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 540 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 430 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 492 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 442 bp overlap
ChIP foregut GSE117136.GATA6.foregut 467 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 381 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 395 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 355 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 485 bp overlap
GFI1B 2 datasets
ChIP K-562 ENCSR509GDT.GFI1B.K-562 111 bp overlap
ChIP K-562_Wnt GSE117944.GFI1B.K-562_Wnt 170 bp overlap
GLIS1 2 datasets
ChIP HEK293 ENCFF299RSE 115 bp overlap
ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 357 bp overlap
Gata3 2 datasets
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
HES1 2 datasets
ChIP K-562 ENCSR091JXL.HES1.K-562 370 bp overlap
ChIP K562 ENCFF919JVU 248 bp overlap
HIF1A 1 dataset
ChIP U2OS_trough_DMOG GSE85096.HIF1A.U2OS_trough_DMOG 184 bp overlap
IRF3 4 datasets
Motif DE_36h DE_36h-IRF3_MA1418.2 17 bp overlap
Motif DE_48h DE_48h-IRF3_MA1418.2 17 bp overlap
Motif DE_60h DE_60h-IRF3_MA1418.2 17 bp overlap
Motif DE_72h DE_72h-IRF3_MA1418.2 17 bp overlap
IRF9 4 datasets
Motif DE_36h DE_36h-IRF9_MA0653.1 15 bp overlap
Motif DE_48h DE_48h-IRF9_MA0653.1 15 bp overlap
Motif DE_60h DE_60h-IRF9_MA0653.1 15 bp overlap
Motif DE_72h DE_72h-IRF9_MA0653.1 15 bp overlap
ISL2 3 datasets
Motif DE_36h DE_36h-ISL2_MA0914.2 6 bp overlap
Motif DE_48h DE_48h-ISL2_MA0914.2 6 bp overlap
Motif DE_72h DE_72h-ISL2_MA0914.2 6 bp overlap
JARID2 1 dataset
ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 203 bp overlap
KDM1A 2 datasets
ChIP K-562 GSE117944.KDM1A.K-562 204 bp overlap
ChIP K-562_Wnt GSE117944.KDM1A.K-562_Wnt 209 bp overlap
KLF5 1 dataset
ChIP HEK293_D418N GSE88976.KLF5.HEK293_D418N 237 bp overlap
NFIA 3 datasets
Motif DE_36h DE_36h-NFIA_MA0670.2 6 bp overlap
Motif DE_48h DE_48h-NFIA_MA0670.2 6 bp overlap
Motif DE_72h DE_72h-NFIA_MA0670.2 6 bp overlap
NFIX 3 datasets
Motif DE_36h DE_36h-NFIX_MA0671.2 6 bp overlap
Motif DE_48h DE_48h-NFIX_MA0671.2 6 bp overlap
Motif DE_72h DE_72h-NFIX_MA0671.2 6 bp overlap
NR2F2 1 dataset
ChIP K-562 ENCSR000BRS.NR2F2.K-562 171 bp overlap
Nkx3-1 3 datasets
Motif DE_36h DE_36h-Nkx3-1_MA0124.3 7 bp overlap
Motif DE_48h DE_48h-Nkx3-1_MA0124.3 7 bp overlap
Motif DE_72h DE_72h-Nkx3-1_MA0124.3 7 bp overlap
Nkx3-2 3 datasets
Motif DE_36h DE_36h-Nkx3-2_MA0122.4 10 bp overlap
Motif DE_48h DE_48h-Nkx3-2_MA0122.4 10 bp overlap
Motif DE_72h DE_72h-Nkx3-2_MA0122.4 10 bp overlap
PGR 3 datasets
Motif DE_36h DE_36h-PGR_MA2327.1 9 bp overlap
Motif DE_48h DE_48h-PGR_MA2327.1 9 bp overlap
Motif DE_72h DE_72h-PGR_MA2327.1 9 bp overlap
Pou5f1::Sox2 3 datasets
Motif DE_36h DE_36h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif DE_48h DE_48h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif DE_72h DE_72h-Pou5f1Sox2_MA0142.1 15 bp overlap
RNF2 1 dataset
ChIP K-562 ENCSR138FUZ.RNF2.K-562 117 bp overlap
RUNX2 1 dataset
ChIP LNCaP-C4-2B GSE33889.RUNX2.LNCaP-C4-2B 661 bp overlap
Rarb 4 datasets
Motif DE_36h DE_36h-Rarb_MA0857.1 16 bp overlap
Motif DE_48h DE_48h-Rarb_MA0857.1 16 bp overlap
Motif DE_60h DE_60h-Rarb_MA0857.1 16 bp overlap
Motif DE_72h DE_72h-Rarb_MA0857.1 16 bp overlap
SCRT1 2 datasets
ChIP HEK293 ENCFF513YVP 356 bp overlap
ChIP HEK293 ENCSR605MGM.SCRT1.HEK293 295 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 611 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 315 bp overlap
SMAD2_3 3 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 279 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 636 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 262 bp overlap
SMARCA4 1 dataset
ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 344 bp overlap
SOX10 3 datasets
Motif DE_36h DE_36h-SOX10_MA0442.3 6 bp overlap
Motif DE_48h DE_48h-SOX10_MA0442.3 6 bp overlap
Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 394 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 512 bp overlap
SOX4 3 datasets
Motif DE_36h DE_36h-SOX4_MA0867.3 8 bp overlap
Motif DE_48h DE_48h-SOX4_MA0867.3 8 bp overlap
Motif DE_72h DE_72h-SOX4_MA0867.3 8 bp overlap
SOX6 1 dataset
ChIP K-562 ENCSR788RSW.SOX6.K-562 263 bp overlap
SREBF1 3 datasets
Motif DE_36h DE_36h-SREBF1_MA0595.1 10 bp overlap
Motif DE_48h DE_48h-SREBF1_MA0595.1 10 bp overlap
Motif DE_72h DE_72h-SREBF1_MA0595.1 10 bp overlap
Sox11 3 datasets
Motif DE_36h DE_36h-Sox11_MA0869.3 8 bp overlap
Motif DE_48h DE_48h-Sox11_MA0869.3 8 bp overlap
Motif DE_72h DE_72h-Sox11_MA0869.3 8 bp overlap
Sox6 3 datasets
Motif DE_36h DE_36h-Sox6_MA0515.1 10 bp overlap
Motif DE_48h DE_48h-Sox6_MA0515.1 10 bp overlap
Motif DE_72h DE_72h-Sox6_MA0515.1 10 bp overlap
T 2 datasets
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 270 bp overlap
ChIP H9_MESODERM GSE60606.T.H9_MESODERM 319 bp overlap
TAL1 6 datasets
ChIP K-562 GSE107726.TAL1.K-562 281 bp overlap
ChIP K-562 ENCSR000EHB.TAL1.K-562 159 bp overlap
ChIP K-562_dCas9-LSD1 GSE132212.TAL1.K-562_dCas9-LSD1 254 bp overlap
ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 187 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 256 bp overlap
ChIP K-562_sgGal4 GSE132212.TAL1.K-562_sgGal4 191 bp overlap
TBL1X 1 dataset
ChIP HEK293T GSE35197.TBL1X.HEK293T 189 bp overlap
TCF3 1 dataset
ChIP K-562 ENCSR970OJY.TCF3.K-562 215 bp overlap
TFAP2C 3 datasets
Motif DE_36h DE_36h-TFAP2C_MA0814.3 9 bp overlap
Motif DE_48h DE_48h-TFAP2C_MA0814.3 9 bp overlap
Motif DE_72h DE_72h-TFAP2C_MA0814.3 9 bp overlap
TP53 4 datasets
ChIP MCF-10A_Nutlin3A GSE111009.TP53.MCF-10A_Nutlin3A 70 bp overlap
ChIP MCF-7_nutlin GSE86164.TP53.MCF-7_nutlin 115 bp overlap
ChIP SaOS-2 GSE15780.TP53.SaOS-2 109 bp overlap
ChIP keratinocyte GSE56674.TP53.keratinocyte 57 bp overlap
TP63 10 datasets
ChIP MCF-10A_Nutlin3A GSE111009.TP63.MCF-10A_Nutlin3A 112 bp overlap
ChIP SUIT-2 GSE115461.TP63.SUIT-2 111 bp overlap
ChIP keratinocyte GSE56674.TP63.keratinocyte 131 bp overlap
ChIP keratinocyte_CISP GSE56674.TP63.keratinocyte_CISP 87 bp overlap
ChIP keratinocyte_D0 GSE59824.TP63.keratinocyte_D0 169 bp overlap
ChIP keratinocyte_D2 GSE59824.TP63.keratinocyte_D2 146 bp overlap
ChIP keratinocyte_D4 GSE59824.TP63.keratinocyte_D4 151 bp overlap
ChIP keratinocyte_D7 GSE59824.TP63.keratinocyte_D7 152 bp overlap
ChIP keratinocyte_epidermal GSE67382.TP63.keratinocyte_epidermal 84 bp overlap
ChIP keratinocyte_epidermal_KDPAF GSE67382.TP63.keratinocyte_epidermal_KDPAF 51 bp overlap
TP73_DELTANP 1 dataset
ChIP SaOS-2 GSE15780.TP73_DELTANP.SaOS-2 106 bp overlap
TRPS1 2 datasets
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
ZFP42 3 datasets
Motif DE_36h DE_36h-ZFP42_MA1651.2 13 bp overlap
Motif DE_48h DE_48h-ZFP42_MA1651.2 13 bp overlap
Motif DE_72h DE_72h-ZFP42_MA1651.2 13 bp overlap
ZNF3 1 dataset
ChIP K-562 ENCSR195QFV.ZNF3.K-562 181 bp overlap
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