chr5 : 175,447,194 – 175,447,921
727 bp 49 TFs 2 linked genes
This 727 bp open chromatin element is linked to DRD1 and SFXN1 and is bound by 49 transcription factors.
Linked Genes
2 genes
Distance
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
DRD1 3.0 kb Proximal Proximity
SFXN1 30.9 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr5:175,442,194 – 175,452,921
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
49 transcription factors
Source
Cell type
CBX2 2 datasets
ChIP K-562 ENCSR000ATU.CBX2.K-562 596 bp overlap
ChIP K-562 ENCSR000ATU.CBX2.K-562 53 bp overlap
CBX8 3 datasets
ChIP A549 ENCFF656LMW 376 bp overlap
ChIP K-562 ENCSR000ATW.CBX8.K-562 255 bp overlap
ChIP K-562 ENCSR000ATW.CBX8.K-562 343 bp overlap
E2F6 3 datasets
Motif DE_36h DE_36h-E2F6_MA0471.3 8 bp overlap
Motif DE_48h DE_48h-E2F6_MA0471.3 8 bp overlap
Motif DE_72h DE_72h-E2F6_MA0471.3 8 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 212 bp overlap
EWSR1-FLI1 3 datasets
Motif DE_36h DE_36h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_48h DE_48h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_72h DE_72h-EWSR1-FLI1_MA0149.1 18 bp overlap
EZH2 2 datasets
ChIP A-1847 GSE95643.EZH2.A-1847 52 bp overlap
ChIP THP-1 GSE135024.EZH2.THP-1 192 bp overlap
EZH2_phosphoT487 2 datasets
ChIP neuron_bipolar_doxy_4d ENCSR886KKK.EZH2_phosphoT487.neuron_bipolar_doxy_4d 87 bp overlap
ChIP neuron_bipolar_doxy_4d ENCSR886KKK.EZH2_phosphoT487.neuron_bipolar_doxy_4d 275 bp overlap
FOXA2 4 datasets
ChIP DE DE-FOXA2-1 248 bp overlap
ChIP DE DE-FOXA2-1 397 bp overlap
ChIP DE DE-FOXA2-2 255 bp overlap
ChIP DE DE-FOXA2-2 361 bp overlap
GATA1::TAL1 4 datasets
Motif DE_36h DE_36h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_60h DE_60h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_72h DE_72h-GATA1TAL1_MA0140.3 17 bp overlap
GATA2 2 datasets
ChIP LNCaP_CSFCS GSE69043.GATA2.LNCaP_CSFCS 132 bp overlap
ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 287 bp overlap
GATA4 9 datasets
ChIP DE DE-GATA4-1 687 bp overlap
ChIP DE DE-GATA4-2 727 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP Hep-G2 GSE135714.GATA4.Hep-G2 275 bp overlap
ChIP foregut GSE117136.GATA4.foregut 450 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 299 bp overlap
GATA5 4 datasets
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 11 datasets
ChIP DE DE-GATA6-1 608 bp overlap
ChIP DE DE-GATA6-2 548 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 464 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 654 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 566 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 647 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 682 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 556 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 547 bp overlap
ChIP foregut GSE117136.GATA6.foregut 336 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 376 bp overlap
GLI3 4 datasets
Motif DE_36h DE_36h-GLI3_MA1491.3 15 bp overlap
Motif DE_48h DE_48h-GLI3_MA1491.3 15 bp overlap
Motif DE_60h DE_60h-GLI3_MA1491.3 15 bp overlap
Motif DE_72h DE_72h-GLI3_MA1491.3 15 bp overlap
GLIS1 1 dataset
ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 201 bp overlap
Gli1 4 datasets
Motif DE_36h DE_36h-Gli1_MA1990.2 10 bp overlap
Motif DE_48h DE_48h-Gli1_MA1990.2 10 bp overlap
Motif DE_60h DE_60h-Gli1_MA1990.2 10 bp overlap
Motif DE_72h DE_72h-Gli1_MA1990.2 10 bp overlap
HMBOX1 4 datasets
Motif DE_36h DE_36h-HMBOX1_MA0895.2 7 bp overlap
Motif DE_48h DE_48h-HMBOX1_MA0895.2 7 bp overlap
Motif DE_60h DE_60h-HMBOX1_MA0895.2 7 bp overlap
Motif DE_72h DE_72h-HMBOX1_MA0895.2 7 bp overlap
Hnf1A 3 datasets
Motif DE_36h DE_36h-Hnf1A_MA1991.2 10 bp overlap
Motif DE_48h DE_48h-Hnf1A_MA1991.2 10 bp overlap
Motif DE_72h DE_72h-Hnf1A_MA1991.2 10 bp overlap
JUN 1 dataset
ChIP DE_D2 S02-DE-d2-JUN-exp1 262 bp overlap
MTA2 1 dataset
ChIP RH4 GSE155861.MTA2.RH4 56 bp overlap
NFIX 4 datasets
Motif DE_36h DE_36h-NFIX_MA1528.2 14 bp overlap
Motif DE_48h DE_48h-NFIX_MA1528.2 14 bp overlap
Motif DE_60h DE_60h-NFIX_MA1528.2 14 bp overlap
Motif DE_72h DE_72h-NFIX_MA1528.2 14 bp overlap
NKX2-2 4 datasets
Motif DE_36h DE_36h-NKX2-2_MA1645.2 8 bp overlap
Motif DE_48h DE_48h-NKX2-2_MA1645.2 8 bp overlap
Motif DE_60h DE_60h-NKX2-2_MA1645.2 8 bp overlap
Motif DE_72h DE_72h-NKX2-2_MA1645.2 8 bp overlap
NR1I3 3 datasets
Motif DE_36h DE_36h-NR1I3_MA1534.2 8 bp overlap
Motif DE_48h DE_48h-NR1I3_MA1534.2 8 bp overlap
Motif DE_72h DE_72h-NR1I3_MA1534.2 8 bp overlap
PCGF2 2 datasets
ChIP fibroblast_MET GSE55605.PCGF2.fibroblast_MET 291 bp overlap
ChIP fibroblast_OHT GSE55605.PCGF2.fibroblast_OHT 197 bp overlap
PHIP 1 dataset
ChIP HCT-116_MLL1-KO__ab833 GSE101646.PHIP.HCT-116_MLL1-KO__ab833 727 bp overlap
PHOX2A 4 datasets
Motif DE_36h DE_36h-PHOX2A_MA0713.1 11 bp overlap
Motif DE_48h DE_48h-PHOX2A_MA0713.1 11 bp overlap
Motif DE_60h DE_60h-PHOX2A_MA0713.1 11 bp overlap
Motif DE_72h DE_72h-PHOX2A_MA0713.1 11 bp overlap
PITX3 1 dataset
ChIP SH-SY5Y GSE93275.PITX3.SH-SY5Y 277 bp overlap
POLR2A 1 dataset
ChIP sigmoid colon ENCFF748YVT 207 bp overlap
PRDM9 3 datasets
Motif DE_36h DE_36h-PRDM9_MA1723.2 20 bp overlap
Motif DE_48h DE_48h-PRDM9_MA1723.2 20 bp overlap
Motif DE_72h DE_72h-PRDM9_MA1723.2 20 bp overlap
PROP1 4 datasets
Motif DE_36h DE_36h-PROP1_MA0715.1 11 bp overlap
Motif DE_48h DE_48h-PROP1_MA0715.1 11 bp overlap
Motif DE_60h DE_60h-PROP1_MA0715.1 11 bp overlap
Motif DE_72h DE_72h-PROP1_MA0715.1 11 bp overlap
Pparg::Rxra 1 dataset
Motif DE_72h DE_72h-PpargRxra_MA0065.3 13 bp overlap
RNF2 7 datasets
ChIP A-549 ENCSR798EGJ.RNF2.A-549 315 bp overlap
ChIP A549 ENCFF650XYA 377 bp overlap
ChIP A549 ENCFF650XYA 150 bp overlap
ChIP Hep-G2 ENCSR523XCR.RNF2.Hep-G2 351 bp overlap
ChIP HepG2 ENCFF737WCD 382 bp overlap
ChIP K-562 ENCSR820GND.RNF2.K-562 336 bp overlap
ChIP fibroblast GSE139053.RNF2.fibroblast 275 bp overlap
RUNX2 1 dataset
ChIP LNCaP-C4-2B GSE33889.RUNX2.LNCaP-C4-2B 341 bp overlap
RXRA::VDR 1 dataset
Motif DE_72h DE_72h-RXRAVDR_MA0074.1 15 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 346 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 305 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 291 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 284 bp overlap
SMARCC1 3 datasets
ChIP HS-SY-2 GSE108025.SMARCC1.HS-SY-2 406 bp overlap
ChIP SYO-1_shCt GSE139053.SMARCC1.SYO-1_shCt 568 bp overlap
ChIP SYO-1_shRING1A-B GSE139053.SMARCC1.SYO-1_shRING1A-B 314 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 333 bp overlap
SOX8 1 dataset
ChIP RH4_Entinostat-6H GSE116344.SOX8.RH4_Entinostat-6H 201 bp overlap
SP5 3 datasets
Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 275 bp overlap
THAP1 4 datasets
Motif DE_36h DE_36h-THAP1_MA0597.3 8 bp overlap
Motif DE_48h DE_48h-THAP1_MA0597.3 8 bp overlap
Motif DE_60h DE_60h-THAP1_MA0597.3 8 bp overlap
Motif DE_72h DE_72h-THAP1_MA0597.3 8 bp overlap
ZBTB26 4 datasets
Motif DE_36h DE_36h-ZBTB26_MA1579.2 8 bp overlap
Motif DE_48h DE_48h-ZBTB26_MA1579.2 8 bp overlap
Motif DE_60h DE_60h-ZBTB26_MA1579.2 8 bp overlap
Motif DE_72h DE_72h-ZBTB26_MA1579.2 8 bp overlap
ZFP14 3 datasets
Motif DE_36h DE_36h-ZFP14_MA1972.1 15 bp overlap
Motif DE_48h DE_48h-ZFP14_MA1972.1 15 bp overlap
Motif DE_72h DE_72h-ZFP14_MA1972.1 15 bp overlap
ZNF257 3 datasets
Motif DE_36h DE_36h-ZNF257_MA1710.2 10 bp overlap
Motif DE_48h DE_48h-ZNF257_MA1710.2 10 bp overlap
Motif DE_72h DE_72h-ZNF257_MA1710.2 10 bp overlap
ZNF354A 3 datasets
Motif DE_36h DE_36h-ZNF354A_MA1978.2 20 bp overlap
Motif DE_48h DE_48h-ZNF354A_MA1978.2 20 bp overlap
Motif DE_72h DE_72h-ZNF354A_MA1978.2 20 bp overlap
ZNF677 3 datasets
Motif DE_36h DE_36h-ZNF677_MA2101.1 12 bp overlap
Motif DE_48h DE_48h-ZNF677_MA2101.1 12 bp overlap
Motif DE_72h DE_72h-ZNF677_MA2101.1 12 bp overlap
ZNF770 5 datasets
Motif DE_36h DE_36h-ZNF770_MA2099.1 8 bp overlap
Motif DE_48h DE_48h-ZNF770_MA2099.1 8 bp overlap
Motif DE_72h DE_72h-ZNF770_MA2099.1 8 bp overlap
ChIP HEK293 ENCSR242BGR.ZNF770.HEK293 215 bp overlap
ChIP HEK293 GSE76494.ZNF770.HEK293 177 bp overlap
Znf423 4 datasets
Motif DE_36h DE_36h-Znf423_MA0116.1 15 bp overlap
Motif DE_48h DE_48h-Znf423_MA0116.1 15 bp overlap
Motif DE_60h DE_60h-Znf423_MA0116.1 15 bp overlap
Motif DE_72h DE_72h-Znf423_MA0116.1 15 bp overlap
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