chr6 : 156,655,335 – 156,656,025

690 bp 157 TFs 4 linked genes

This 690 bp open chromatin element is linked to 4 target genes and is bound by 157 transcription factors.

Linked Genes

4 genes

Gene	Dist. to TSS	Distance	Link type
H3P28	6.0 kb	Proximal	Proximity
ARID1B	121.7 kb	Distal	Multiome
ENSG00000287092	258.1 kb	Distal	Multiome
TFB1M	1341.3 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

157 transcription factors

ALX3 1 dataset

Motif DE_12h DE_12h-ALX3_MA0634.2 6 bp overlap

ARGFX 1 dataset

Motif DE_12h DE_12h-ARGFX_MA1463.2 8 bp overlap

ASCL1 1 dataset

Motif DE_12h DE_12h-ASCL1_MA1100.3 8 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 447 bp overlap

ATF2 1 dataset

ChIP WA01 ENCSR000BQU.ATF2.WA01 406 bp overlap

Alx1 1 dataset

Motif DE_12h DE_12h-Alx1_MA0854.2 8 bp overlap

Alx4 1 dataset

Motif DE_12h DE_12h-Alx4_MA0853.2 12 bp overlap

Arx 1 dataset

Motif DE_12h DE_12h-Arx_MA0874.2 10 bp overlap

Ascl2 1 dataset

Motif DE_12h DE_12h-Ascl2_MA0816.1 10 bp overlap

BCL11A 2 datasets

ChIP WA01 ENCSR000BMJ.BCL11A.WA01 157 bp overlap

ChIP WA01 ENCSR000BIP.BCL11A.WA01 110 bp overlap

BCOR 2 datasets

ChIP WA01 GSE104690.BCOR.WA01 359 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 325 bp overlap

BHLHE22 1 dataset

Motif DE_12h DE_12h-BHLHE22_MA1635.2 6 bp overlap

BRD1 1 dataset

ChIP HUES-64 GSE104059.BRD1.HUES-64 257 bp overlap

Bhlha15 1 dataset

Motif DE_12h DE_12h-Bhlha15_MA1472.3 8 bp overlap

CHD4 1 dataset

ChIP 501-mel GSE134848.CHD4.501-mel 127 bp overlap

CHD7 1 dataset

ChIP H1 ENCFF126NLU 584 bp overlap

CTBP2 2 datasets

ChIP H1 ENCFF329MAX 591 bp overlap

ChIP WA01 ENCSR000EUO.CTBP2.WA01 611 bp overlap

DRGX 1 dataset

Motif DE_12h DE_12h-DRGX_MA1481.2 6 bp overlap

DUXA 1 dataset

Motif DE_12h DE_12h-DUXA_MA0884.2 13 bp overlap

EBF1 2 datasets

Motif ES_0h ES_0h-EBF1_MA0154.5 11 bp overlap

ChIP MUTUL GSE75503.EBF1.MUTUL 267 bp overlap

EBF3 1 dataset

Motif ES_0h ES_0h-EBF3_MA1637.2 9 bp overlap

EED 1 dataset

ChIP ProEs GSE59087.EED.ProEs 131 bp overlap

ELF1 1 dataset

Motif DE_12h DE_12h-ELF1_MA0473.4 9 bp overlap

EMX1 1 dataset

Motif DE_12h DE_12h-EMX1_MA0612.3 6 bp overlap

EMX2 1 dataset

Motif DE_12h DE_12h-EMX2_MA0886.2 6 bp overlap

EN1 1 dataset

Motif DE_12h DE_12h-EN1_MA0027.3 6 bp overlap

EN2 1 dataset

Motif DE_12h DE_12h-EN2_MA0642.3 7 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 178 bp overlap

EP300 2 datasets

ChIP H1 ENCFF927IYK 297 bp overlap

ChIP WA01 ENCSR000BKK.EP300.WA01 233 bp overlap

ERF::HOXB13 1 dataset

Motif ES_0h ES_0h-ERFHOXB13_MA1937.2 13 bp overlap

ESX1 1 dataset

Motif DE_12h DE_12h-ESX1_MA0644.3 7 bp overlap

ETV6 1 dataset

ChIP WTC11 ENCFF812SCD 413 bp overlap

EVX1 1 dataset

Motif DE_12h DE_12h-EVX1_MA0887.2 6 bp overlap

EVX2 1 dataset

Motif DE_12h DE_12h-EVX2_MA0888.2 6 bp overlap

Ebf2 1 dataset

Motif ES_0h ES_0h-Ebf2_MA1604.2 9 bp overlap

Ebf4 1 dataset

Motif ES_0h ES_0h-Ebf4_MA2122.1 11 bp overlap

FERD3L 1 dataset

Motif DE_12h DE_12h-FERD3L_MA1485.1 14 bp overlap

FOXP1 1 dataset

ChIP H9 GSE31006.FOXP1.H9 337 bp overlap

GABPA 1 dataset

Motif DE_12h DE_12h-GABPA_MA0062.4 10 bp overlap

GBX1 1 dataset

Motif DE_12h DE_12h-GBX1_MA0889.2 7 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 360 bp overlap

GSX1 1 dataset

Motif DE_12h DE_12h-GSX1_MA0892.2 6 bp overlap

GSX2 1 dataset

Motif DE_12h DE_12h-GSX2_MA0893.3 7 bp overlap

HDAC2 4 datasets

ChIP H1 ENCFF353UJQ 175 bp overlap

ChIP H1 ENCFF939VKA 237 bp overlap

ChIP WA01 ENCSR000AVB.HDAC2.WA01 344 bp overlap

ChIP WA01 ENCSR000BNR.HDAC2.WA01 232 bp overlap

HOXA1 1 dataset

Motif DE_12h DE_12h-HOXA1_MA1495.2 6 bp overlap

HOXA2 1 dataset

Motif DE_12h DE_12h-HOXA2_MA0900.3 6 bp overlap

HOXA3 1 dataset

Motif DE_12h DE_12h-HOXA3_MA2119.1 7 bp overlap

HOXB1 1 dataset

Motif DE_12h DE_12h-HOXB1_MA2093.1 7 bp overlap

HOXB2 1 dataset

Motif DE_12h DE_12h-HOXB2_MA0902.3 6 bp overlap

HOXB3 1 dataset

Motif DE_12h DE_12h-HOXB3_MA0903.2 6 bp overlap

HOXB5 1 dataset

Motif DE_12h DE_12h-HOXB5_MA0904.3 6 bp overlap

HOXC8 1 dataset

Motif DE_12h DE_12h-HOXC8_MA1505.2 6 bp overlap

HOXD3 1 dataset

Motif DE_12h DE_12h-HOXD3_MA0912.2 8 bp overlap

ISL2 1 dataset

Motif DE_12h DE_12h-ISL2_MA0914.2 6 bp overlap

ISX 1 dataset

Motif DE_12h DE_12h-ISX_MA0654.2 6 bp overlap

Ikzf3 1 dataset

Motif DE_12h DE_12h-Ikzf3_MA1992.2 9 bp overlap

JUND 1 dataset

ChIP WA01 ENCSR000BKP.JUND.WA01 151 bp overlap

KDM1A 1 dataset

ChIP H1 ENCFF696SGD 138 bp overlap

LBX1 1 dataset

Motif DE_12h DE_12h-LBX1_MA0618.2 7 bp overlap

LHX5 1 dataset

Motif DE_12h DE_12h-LHX5_MA1519.2 7 bp overlap

LHX6 1 dataset

Motif DE_12h DE_12h-LHX6_MA0658.2 8 bp overlap

LHX9 1 dataset

Motif DE_12h DE_12h-LHX9_MA0701.3 7 bp overlap

LMX1A 1 dataset

Motif DE_12h DE_12h-LMX1A_MA0702.3 7 bp overlap

LMX1B 1 dataset

Motif DE_12h DE_12h-LMX1B_MA0703.3 8 bp overlap

Lhx1 1 dataset

Motif DE_12h DE_12h-Lhx1_MA1518.3 10 bp overlap

Lhx4 1 dataset

Motif DE_12h DE_12h-Lhx4_MA0704.2 6 bp overlap

Lhx8 1 dataset

Motif DE_12h DE_12h-Lhx8_MA0705.2 6 bp overlap

MAX 2 datasets

ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 171 bp overlap

ChIP WA01 ENCSR000EUP.MAX.WA01 138 bp overlap

MED1 1 dataset

ChIP NCI-H2171 GSE36354.MED1.NCI-H2171 178 bp overlap

MED26 1 dataset

ChIP HEK293T GSE121024.MED26.HEK293T 226 bp overlap

MEOX1 1 dataset

Motif DE_12h DE_12h-MEOX1_MA0661.2 7 bp overlap

MEOX2 1 dataset

Motif DE_12h DE_12h-MEOX2_MA0706.2 7 bp overlap

MIXL1 1 dataset

Motif DE_12h DE_12h-MIXL1_MA0662.2 6 bp overlap

MNX1 1 dataset

Motif DE_12h DE_12h-MNX1_MA0707.3 6 bp overlap

MORC2 1 dataset

ChIP H9 GSE95374.MORC2.H9 301 bp overlap

MSC 1 dataset

Motif DE_12h DE_12h-MSC_MA0665.1 10 bp overlap

MYF5 1 dataset

Motif DE_12h DE_12h-MYF5_MA1641.2 8 bp overlap

MYF6 1 dataset

Motif DE_12h DE_12h-MYF6_MA0667.1 10 bp overlap

MYOD1 1 dataset

Motif DE_12h DE_12h-MYOD1_MA0499.3 9 bp overlap

MYOG 1 dataset

Motif DE_12h DE_12h-MYOG_MA0500.3 8 bp overlap

NANOG 9 datasets

ChIP GM23338 ENCFF065NZG 311 bp overlap

ChIP H1 ENCFF747ZPQ 111 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 607 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 569 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 325 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 613 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 426 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 339 bp overlap

ChIP hESC GSE18292.NANOG.hESC 138 bp overlap

NHLH1 1 dataset

Motif DE_12h DE_12h-NHLH1_MA0048.3 9 bp overlap

NHLH2 1 dataset

Motif DE_12h DE_12h-NHLH2_MA1529.2 16 bp overlap

NIPBL 2 datasets

ChIP hESC GSE64758.NIPBL.hESC 213 bp overlap

ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 223 bp overlap

NKX6-1 1 dataset

Motif DE_12h DE_12h-NKX6-1_MA0674.2 7 bp overlap

NKX6-2 1 dataset

Motif DE_12h DE_12h-NKX6-2_MA0675.2 6 bp overlap

NOTO 1 dataset

Motif DE_12h DE_12h-NOTO_MA0710.2 7 bp overlap

Neurod2 1 dataset

Motif DE_12h DE_12h-Neurod2_MA1993.2 6 bp overlap

OTX2 1 dataset

ChIP WTC11 ENCFF634NAO 245 bp overlap

Olig2 1 dataset

Motif DE_12h DE_12h-Olig2_MA1997.2 6 bp overlap

PAX4 1 dataset

Motif DE_12h DE_12h-PAX4_MA0068.2 8 bp overlap

PDX1 1 dataset

Motif DE_12h DE_12h-PDX1_MA0132.3 6 bp overlap

PHOX2A 1 dataset

Motif DE_12h DE_12h-PHOX2A_MA0713.1 11 bp overlap

POU5F1 5 datasets

ChIP HUES-8 GSE109524.POU5F1.HUES-8 636 bp overlap

ChIP NCCIT GSE36134.POU5F1.NCCIT 320 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 545 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 474 bp overlap

ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 307 bp overlap

POU6F1 1 dataset

Motif DE_12h DE_12h-POU6F1_MA0628.2 6 bp overlap

POU6F2 1 dataset

Motif DE_12h DE_12h-POU6F2_MA0793.2 9 bp overlap

PROP1 1 dataset

Motif DE_12h DE_12h-PROP1_MA0715.1 11 bp overlap

PRRX1 1 dataset

Motif DE_12h DE_12h-PRRX1_MA0716.2 6 bp overlap

PRRX2 1 dataset

Motif DE_12h DE_12h-PRRX2_MA0075.4 7 bp overlap

Ptf1A 1 dataset

Motif DE_12h DE_12h-Ptf1A_MA1619.2 8 bp overlap

RAX2 1 dataset

Motif DE_12h DE_12h-RAX2_MA0717.2 6 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 137 bp overlap

RBPJ 1 dataset

Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap

REST 1 dataset

Motif DE_12h DE_12h-REST_MA0138.3 20 bp overlap

SALL3 1 dataset

ChIP hiPSC GSE104863.SALL3.hiPSC 335 bp overlap

SAP30 1 dataset

ChIP WA01 ENCSR000ATR.SAP30.WA01 213 bp overlap

SCRT2 1 dataset

Motif DE_12h DE_12h-SCRT2_MA0744.3 10 bp overlap

SHOX 1 dataset

Motif DE_12h DE_12h-SHOX_MA0630.2 6 bp overlap

SMAD2 1 dataset

Motif DE_12h DE_12h-SMAD2_MA1964.2 6 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 333 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 326 bp overlap

SMAD2_3 1 dataset

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 268 bp overlap

SMAD3 2 datasets

ChIP BG03_DIFF_0H GSE36578.SMAD3.BG03_DIFF_0H 271 bp overlap

ChIP BG03_DIFF_2H GSE36578.SMAD3.BG03_DIFF_2H 233 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 472 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 468 bp overlap

SMARCB1 2 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 315 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 471 bp overlap

SMARCC1 2 datasets

ChIP hiPSC GSE124903.SMARCC1.hiPSC 402 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 381 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 263 bp overlap

SOX2 5 datasets

ChIP H9 GSE46837.SOX2.H9 183 bp overlap

ChIP HNSC GSE69479.SOX2.HNSC 235 bp overlap

ChIP hESC GSE69479.SOX2.hESC 237 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 392 bp overlap

ChIP hiPSC_3s2 GSE81899.SOX2.hiPSC_3s2 290 bp overlap

SOX8 1 dataset

ChIP RH4 GSE116344.SOX8.RH4 226 bp overlap

SP1 2 datasets

Motif DE_12h DE_12h-SP1_MA0079.5 9 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 280 bp overlap

SP4 1 dataset

Motif DE_12h DE_12h-SP4_MA0685.2 9 bp overlap

SP5 1 dataset

Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap

SREBF1 1 dataset

Motif DE_12h DE_12h-SREBF1_MA0595.1 10 bp overlap

Shox2 1 dataset

Motif DE_12h DE_12h-Shox2_MA0720.2 6 bp overlap

T 2 datasets

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 309 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 358 bp overlap

TAL1::TCF3 1 dataset

Motif DE_12h DE_12h-TAL1TCF3_MA0091.2 10 bp overlap

TCF12 2 datasets

ChIP H1 ENCFF203EBH 251 bp overlap

ChIP WA01 ENCSR000BIT.TCF12.WA01 314 bp overlap

TCF3 1 dataset

ChIP NPC GSE154479.TCF3.NPC 443 bp overlap

TFAP4 1 dataset

Motif DE_12h DE_12h-TFAP4_MA0691.1 10 bp overlap

TFAP4::FLI1 1 dataset

Motif DE_12h DE_12h-TFAP4FLI1_MA1967.2 14 bp overlap

TLX2 1 dataset

Motif DE_12h DE_12h-TLX2_MA1577.2 6 bp overlap

TP53 2 datasets

ChIP hESC_DAMAGED GSE39912.TP53.hESC_DAMAGED 206 bp overlap

ChIP hESC_DIFF GSE39912.TP53.hESC_DIFF 389 bp overlap

Tcf12 1 dataset

Motif DE_12h DE_12h-Tcf12_MA0521.3 6 bp overlap

Tcf21 1 dataset

Motif DE_12h DE_12h-Tcf21_MA0832.2 10 bp overlap

Twist2 1 dataset

Motif DE_12h DE_12h-Twist2_MA0633.3 6 bp overlap

UNCX 1 dataset

Motif DE_12h DE_12h-UNCX_MA0721.2 6 bp overlap

VAX1 1 dataset

Motif DE_12h DE_12h-VAX1_MA0722.2 7 bp overlap

VAX2 1 dataset

Motif DE_12h DE_12h-VAX2_MA0723.3 6 bp overlap

VSX1 1 dataset

Motif DE_12h DE_12h-VSX1_MA0725.2 7 bp overlap

VSX2 1 dataset

Motif DE_12h DE_12h-VSX2_MA0726.2 7 bp overlap

Wt1 1 dataset

Motif DE_12h DE_12h-Wt1_MA1627.2 10 bp overlap

YY1 2 datasets

ChIP H1 ENCFF524BTL 337 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 408 bp overlap

ZIM3 1 dataset

Motif DE_12h DE_12h-ZIM3_MA1709.2 11 bp overlap

ZKSCAN5 1 dataset

Motif DE_12h DE_12h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF148 1 dataset

Motif DE_12h DE_12h-ZNF148_MA1653.2 10 bp overlap

ZNF207 1 dataset

ChIP WA09 GSE118632.ZNF207.WA09 320 bp overlap

ZNF263 1 dataset

Motif DE_12h DE_12h-ZNF263_MA0528.3 7 bp overlap

ZNF281 1 dataset

Motif DE_12h DE_12h-ZNF281_MA1630.3 10 bp overlap

ZNF331 1 dataset

Motif DE_12h DE_12h-ZNF331_MA1726.2 10 bp overlap

ZNF384 1 dataset

Motif ES_0h ES_0h-ZNF384_MA1125.2 8 bp overlap

ZNF423 1 dataset

ChIP WTC11 ENCFF574PBR 253 bp overlap

ZNF462 2 datasets

ChIP GM23338 ENCFF896CCA 251 bp overlap

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 670 bp overlap

ZNF682 1 dataset

Motif ES_0h ES_0h-ZNF682_MA1599.2 11 bp overlap

ZNF701 1 dataset

Motif DE_12h DE_12h-ZNF701_MA1987.2 17 bp overlap

ZNF816 1 dataset

Motif DE_12h DE_12h-ZNF816_MA1719.2 15 bp overlap

ZSCAN18 1 dataset

ChIP WTC11 ENCFF867QWX 257 bp overlap

Zfp809 1 dataset

Motif DE_12h DE_12h-Zfp809_MA2125.1 9 bp overlap

mix-a 1 dataset

Motif DE_12h DE_12h-mix-a_MA0621.2 7 bp overlap