chr6 : 166,174,021 – 166,174,725

704 bp 62 TFs 2 linked genes

This 704 bp open chromatin element is linked to LNCDAT and TBXT and is bound by 62 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
LNCDAT		6.1 kb	Proximal	Proximity
TBXT		6.2 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

62 transcription factors

BORCS8-MEF2B,MEF2B 1 dataset

ChIP GM12878 ENCFF427QAI 57 bp overlap

BRD4 7 datasets

ChIP GM15850_DMSO GSE99402.BRD4.GM15850_DMSO 393 bp overlap

ChIP GM15850_DMSO GSE99402.BRD4.GM15850_DMSO 90 bp overlap

ChIP GM15850_PA1_JQ1 GSE99402.BRD4.GM15850_PA1_JQ1 296 bp overlap

ChIP GM15850_Syn-TEF1 GSE99402.BRD4.GM15850_Syn-TEF1 673 bp overlap

ChIP HEK293_sgNT GSE129407.BRD4.HEK293_sgNT 306 bp overlap

ChIP SW480 GSE110473.BRD4.SW480 208 bp overlap

ChIP SW480_16h_TNF-a GSE110473.BRD4.SW480_16h_TNF-a 105 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF274GAT 87 bp overlap

E2F6 3 datasets

Motif DE_24h DE_24h-E2F6_MA0471.3 8 bp overlap

Motif DE_36h DE_36h-E2F6_MA0471.3 8 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 120 bp overlap

EBF1 1 dataset

ChIP GM12878 ENCFF167CZS 321 bp overlap

ETS1 1 dataset

ChIP THP-6_shCtrl GSE138516.ETS1.THP-6_shCtrl 101 bp overlap

EZH2 5 datasets

ChIP A-1847 GSE95643.EZH2.A-1847 216 bp overlap

ChIP A-1847_CARM1-KO GSE95643.EZH2.A-1847_CARM1-KO 498 bp overlap

ChIP GM23338 ENCSR045YHA.EZH2.GM23338 193 bp overlap

ChIP THP-1 GSE135024.EZH2.THP-1 205 bp overlap

ChIP WA01 ENCSR000ASY.EZH2.WA01 84 bp overlap

Ebf2 1 dataset

Motif DE_12h DE_12h-Ebf2_MA1604.2 9 bp overlap

FIGLA 2 datasets

Motif DE_24h DE_24h-FIGLA_MA0820.2 6 bp overlap

Motif DE_36h DE_36h-FIGLA_MA0820.2 6 bp overlap

GATA6 3 datasets

ChIP DE_D1 S09-DE-d1-GATA6-exp1 677 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 661 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 674 bp overlap

HOXC11 2 datasets

Motif DE_24h DE_24h-HOXC11_MA0651.3 11 bp overlap

HOXC12 1 dataset

Motif DE_24h DE_24h-HOXC12_MA0906.2 10 bp overlap

HOXD10 1 dataset

Motif DE_24h DE_24h-HOXD10_MA1506.2 10 bp overlap

HOXD11 1 dataset

Motif DE_24h DE_24h-HOXD11_MA0908.2 9 bp overlap

Hmga1 1 dataset

Motif DE_24h DE_24h-Hmga1_MA2124.1 8 bp overlap

JUN 4 datasets

ChIP DE_D1 S08-DE-d1-JUN-exp1 512 bp overlap

ChIP DE_D1 S13-DE-d1-JUN-exp1 315 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 480 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 543 bp overlap

MED1 1 dataset

ChIP GM12878 GSE93080.MED1.GM12878 549 bp overlap

MEF2B 1 dataset

ChIP GM12878 ENCSR177VFS.MEF2B.GM12878 195 bp overlap

MGA::EVX1 1 dataset

Motif DE_24h DE_24h-MGAEVX1_MA1960.2 11 bp overlap

MYOD1 2 datasets

Motif DE_24h DE_24h-MYOD1_MA0499.3 9 bp overlap

Motif DE_36h DE_36h-MYOD1_MA0499.3 9 bp overlap

NFATC3 1 dataset

Motif DE_24h DE_24h-NFATC3_MA0625.3 6 bp overlap

NIPBL 1 dataset

ChIP GM12878 GSE93080.NIPBL.GM12878 198 bp overlap

Nfatc1 1 dataset

Motif DE_24h DE_24h-Nfatc1_MA0624.3 6 bp overlap

PAX5 1 dataset

ChIP GM12878 ENCSR000BHJ.PAX5.GM12878 143 bp overlap

PLAG1 2 datasets

Motif DE_12h DE_12h-PLAG1_MA0163.1 14 bp overlap

Motif DE_24h DE_24h-PLAG1_MA0163.1 14 bp overlap

POLR2A 1 dataset

ChIP GM12891 ENCFF012SUT 266 bp overlap

POU1F1 1 dataset

Motif DE_24h DE_24h-POU1F1_MA0784.3 14 bp overlap

POU2F2 1 dataset

Motif DE_24h DE_24h-POU2F2_MA0507.3 13 bp overlap

POU3F1 1 dataset

Motif DE_24h DE_24h-POU3F1_MA0786.2 10 bp overlap

POU3F2 1 dataset

Motif DE_24h DE_24h-POU3F2_MA0787.1 12 bp overlap

POU3F3 1 dataset

Motif DE_24h DE_24h-POU3F3_MA0788.1 13 bp overlap

PPARA::RXRA 1 dataset

Motif DE_24h DE_24h-PPARARXRA_MA1148.2 17 bp overlap

Pparg::Rxra 1 dataset

Motif DE_24h DE_24h-PpargRxra_MA0065.3 13 bp overlap

Ptf1A 2 datasets

Motif DE_24h DE_24h-Ptf1A_MA1620.2 8 bp overlap

Motif DE_36h DE_36h-Ptf1A_MA1620.2 8 bp overlap

RBPJ 2 datasets

Motif DE_24h DE_24h-RBPJ_MA1116.2 6 bp overlap

Motif DE_36h DE_36h-RBPJ_MA1116.2 6 bp overlap

REL 1 dataset

Motif DE_24h DE_24h-REL_MA0101.1 10 bp overlap

SMAD2 1 dataset

Motif DE_24h DE_24h-SMAD2_MA1964.2 6 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 568 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 571 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 476 bp overlap

SMARCC1 1 dataset

ChIP DE_D1 S15-DE-d1-BAF155-exp1 550 bp overlap

SNAI2 2 datasets

Motif DE_24h DE_24h-SNAI2_MA0745.3 8 bp overlap

Motif DE_36h DE_36h-SNAI2_MA0745.3 8 bp overlap

SNAI3 2 datasets

Motif DE_24h DE_24h-SNAI3_MA1559.2 9 bp overlap

Motif DE_36h DE_36h-SNAI3_MA1559.2 9 bp overlap

SOX10 1 dataset

Motif DE_24h DE_24h-SOX10_MA0442.3 6 bp overlap

SOX4 1 dataset

Motif DE_24h DE_24h-SOX4_MA0867.3 8 bp overlap

SP1 1 dataset

ChIP GM12878 ENCSR000BHK.SP1.GM12878 119 bp overlap

SP5 2 datasets

Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap

Motif DE_24h DE_24h-SP5_MA1965.2 6 bp overlap

SPIC 1 dataset

Motif DE_24h DE_24h-SPIC_MA0687.2 13 bp overlap

SS18 1 dataset

ChIP Aska-SS GSE108025.SS18.Aska-SS 231 bp overlap

SUZ12 2 datasets

ChIP CRL-7250_shSS18-SSX GSE108025.SUZ12.CRL-7250_shSS18-SSX 337 bp overlap

ChIP hiPSC GSE124903.SUZ12.hiPSC 116 bp overlap

Sox6 1 dataset

Motif DE_24h DE_24h-Sox6_MA0515.1 10 bp overlap

T 2 datasets

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 179 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 227 bp overlap

TBX19 2 datasets

Motif DE_24h DE_24h-TBX19_MA0804.2 17 bp overlap

Motif DE_36h DE_36h-TBX19_MA0804.2 17 bp overlap

TBXT 2 datasets

Motif DE_24h DE_24h-TBXT_MA0009.2 16 bp overlap

Motif DE_36h DE_36h-TBXT_MA0009.2 16 bp overlap

TFAP2A 2 datasets

Motif DE_12h DE_12h-TFAP2A_MA0810.2 11 bp overlap

Motif DE_24h DE_24h-TFAP2A_MA0810.2 11 bp overlap

ZEB1 2 datasets

Motif DE_24h DE_24h-ZEB1_MA0103.4 6 bp overlap

Motif DE_36h DE_36h-ZEB1_MA0103.4 6 bp overlap

ZNF184 1 dataset

Motif DE_24h DE_24h-ZNF184_MA2120.1 13 bp overlap

ZNF213 2 datasets

Motif DE_12h DE_12h-ZNF213_MA2121.1 12 bp overlap

Motif DE_24h DE_24h-ZNF213_MA2121.1 12 bp overlap

ZNF263 2 datasets

Motif DE_12h DE_12h-ZNF263_MA0528.3 7 bp overlap

Motif DE_24h DE_24h-ZNF263_MA0528.3 7 bp overlap

ZNF35 1 dataset

Motif DE_24h DE_24h-ZNF35_MA2333.1 7 bp overlap

ZNF528 1 dataset

ChIP HEK293 GSE76494.ZNF528.HEK293 143 bp overlap

ZNF547 1 dataset

Motif DE_24h DE_24h-ZNF547_MA2334.1 13 bp overlap

ZNF701 2 datasets

Motif DE_12h DE_12h-ZNF701_MA1987.2 17 bp overlap

Motif DE_24h DE_24h-ZNF701_MA1987.2 17 bp overlap

ZNF770 2 datasets

Motif DE_24h DE_24h-ZNF770_MA2099.1 8 bp overlap

ChIP HEK293 GSE76494.ZNF770.HEK293 152 bp overlap