chr7 : 10,931,229 – 10,931,656

427 bp 62 TFs 2 linked genes

This 427 bp open chromatin element is linked to NDUFA4 and ENSG00000271185 and is bound by 62 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
NDUFA4		8.5 kb	Proximal	Proximity
ENSG00000271185		8.8 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

62 transcription factors

Cebpa 1 dataset

ChIP BLaER1 ENCFF031ISE 251 bp overlap

Crx 2 datasets

Motif DE_12h DE_12h-Crx_MA0467.3 6 bp overlap

Motif ES_0h ES_0h-Crx_MA0467.3 6 bp overlap

DDX5 1 dataset

ChIP NTERA2 GSE58641.DDX5.NTERA2 276 bp overlap

Dmbx1 2 datasets

Motif DE_12h DE_12h-Dmbx1_MA0883.2 10 bp overlap

Motif ES_0h ES_0h-Dmbx1_MA0883.2 10 bp overlap

FEZF2 2 datasets

Motif DE_12h DE_12h-FEZF2_MA2341.1 8 bp overlap

Motif ES_0h ES_0h-FEZF2_MA2341.1 8 bp overlap

FOXP2 2 datasets

Motif DE_12h DE_12h-FOXP2_MA0593.2 9 bp overlap

Motif ES_0h ES_0h-FOXP2_MA0593.2 9 bp overlap

GSC 2 datasets

Motif DE_12h DE_12h-GSC_MA0648.2 6 bp overlap

Motif ES_0h ES_0h-GSC_MA0648.2 6 bp overlap

GSC2 2 datasets

Motif DE_12h DE_12h-GSC2_MA0891.2 6 bp overlap

Motif ES_0h ES_0h-GSC2_MA0891.2 6 bp overlap

GTF3C2 1 dataset

ChIP H9 GSE94418.GTF3C2.H9 265 bp overlap

HOXB4 2 datasets

Motif DE_12h DE_12h-HOXB4_MA1499.2 6 bp overlap

Motif ES_0h ES_0h-HOXB4_MA1499.2 6 bp overlap

HOXC4 2 datasets

Motif DE_12h DE_12h-HOXC4_MA1504.2 6 bp overlap

Motif ES_0h ES_0h-HOXC4_MA1504.2 6 bp overlap

HOXD4 2 datasets

Motif DE_12h DE_12h-HOXD4_MA1507.2 6 bp overlap

Motif ES_0h ES_0h-HOXD4_MA1507.2 6 bp overlap

IFNA1 1 dataset

ChIP Huh-7_NS5 GSE110511.IFNA1.Huh-7_NS5 146 bp overlap

MYBL2 1 dataset

ChIP A-673 GSE119971.MYBL2.A-673 199 bp overlap

NANOG 2 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 173 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 195 bp overlap

NKX6-1 2 datasets

Motif DE_12h DE_12h-NKX6-1_MA0674.2 7 bp overlap

Motif ES_0h ES_0h-NKX6-1_MA0674.2 7 bp overlap

OTX1 2 datasets

Motif DE_12h DE_12h-OTX1_MA0711.2 6 bp overlap

Motif ES_0h ES_0h-OTX1_MA0711.2 6 bp overlap

OTX2 2 datasets

Motif DE_12h DE_12h-OTX2_MA0712.3 7 bp overlap

Motif ES_0h ES_0h-OTX2_MA0712.3 7 bp overlap

PITX1 2 datasets

Motif DE_12h DE_12h-PITX1_MA0682.3 6 bp overlap

Motif ES_0h ES_0h-PITX1_MA0682.3 6 bp overlap

PITX3 2 datasets

Motif DE_12h DE_12h-PITX3_MA0714.2 6 bp overlap

Motif ES_0h ES_0h-PITX3_MA0714.2 6 bp overlap

POLR2A 1 dataset

ChIP GM23338 ENCFF450WCS 390 bp overlap

POU1F1 2 datasets

Motif DE_12h DE_12h-POU1F1_MA0784.3 14 bp overlap

Motif ES_0h ES_0h-POU1F1_MA0784.3 14 bp overlap

POU2F1::SOX2 2 datasets

Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap

Motif ES_0h ES_0h-POU2F1SOX2_MA1962.1 17 bp overlap

POU2F2 2 datasets

Motif DE_12h DE_12h-POU2F2_MA0507.3 13 bp overlap

Motif ES_0h ES_0h-POU2F2_MA0507.3 13 bp overlap

POU2F3 1 dataset

ChIP NCI-H1048 GSE115123.POU2F3.NCI-H1048 120 bp overlap

POU3F1 2 datasets

Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap

Motif ES_0h ES_0h-POU3F1_MA0786.2 10 bp overlap

POU3F2 2 datasets

Motif DE_12h DE_12h-POU3F2_MA0787.1 12 bp overlap

Motif ES_0h ES_0h-POU3F2_MA0787.1 12 bp overlap

POU5F1 4 datasets

ChIP HUES-8 GSE109524.POU5F1.HUES-8 245 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 172 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 130 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 135 bp overlap

POU5F1B 2 datasets

Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap

Motif ES_0h ES_0h-POU5F1B_MA0792.1 9 bp overlap

POU6F2 2 datasets

Motif DE_12h DE_12h-POU6F2_MA0793.2 9 bp overlap

Motif ES_0h ES_0h-POU6F2_MA0793.2 9 bp overlap

Pou5f1::Sox2 2 datasets

Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap

Motif ES_0h ES_0h-Pou5f1Sox2_MA0142.1 15 bp overlap

RBFOX2 1 dataset

ChIP HepG2 ENCFF939HTZ 127 bp overlap

RBM22 1 dataset

ChIP HepG2 ENCFF561IAJ 353 bp overlap

RHOXF1 2 datasets

Motif DE_12h DE_12h-RHOXF1_MA0719.2 6 bp overlap

Motif ES_0h ES_0h-RHOXF1_MA0719.2 6 bp overlap

Runx1 2 datasets

Motif DE_12h DE_12h-Runx1_MA0002.3 9 bp overlap

Motif ES_0h ES_0h-Runx1_MA0002.3 9 bp overlap

SMAD2-3 1 dataset

ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 285 bp overlap

SMAD3 1 dataset

ChIP SUM159PT GSE130364.SMAD3.SUM159PT 159 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 125 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 172 bp overlap

SMARCC1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 198 bp overlap

SOX10 2 datasets

Motif DE_12h DE_12h-SOX10_MA0442.3 6 bp overlap

Motif ES_0h ES_0h-SOX10_MA0442.3 6 bp overlap

SOX2 1 dataset

ChIP hiPSC GSE56567.SOX2.hiPSC 216 bp overlap

SOX4 2 datasets

Motif DE_12h DE_12h-SOX4_MA0867.3 8 bp overlap

Motif ES_0h ES_0h-SOX4_MA0867.3 8 bp overlap

SP4 1 dataset

ChIP WA01 ENCSR000BQV.SP4.WA01 67 bp overlap

Sox11 2 datasets

Motif DE_12h DE_12h-Sox11_MA0869.3 8 bp overlap

Motif ES_0h ES_0h-Sox11_MA0869.3 8 bp overlap

Sox5 2 datasets

Motif DE_12h DE_12h-Sox5_MA0087.3 8 bp overlap

Motif ES_0h ES_0h-Sox5_MA0087.3 8 bp overlap

Sox6 2 datasets

Motif DE_12h DE_12h-Sox6_MA0515.1 10 bp overlap

Motif ES_0h ES_0h-Sox6_MA0515.1 10 bp overlap

Sox7 2 datasets

Motif DE_12h DE_12h-Sox7_MA2095.1 10 bp overlap

Motif ES_0h ES_0h-Sox7_MA2095.1 10 bp overlap

TAF1 1 dataset

ChIP WA01 ENCSR000BHO.TAF1.WA01 124 bp overlap

TP53 1 dataset

ChIP hESC_DIFF GSE39912.TP53.hESC_DIFF 56 bp overlap

Yy1 1 dataset

Motif ES_0h ES_0h-Yy1_MA0095.4 8 bp overlap

ZKSCAN1 2 datasets

Motif DE_12h DE_12h-ZKSCAN1_MA1585.2 9 bp overlap

Motif ES_0h ES_0h-ZKSCAN1_MA1585.2 9 bp overlap

ZNF121 1 dataset

ChIP WTC11 ENCFF291API 297 bp overlap

ZNF135 2 datasets

Motif DE_12h DE_12h-ZNF135_MA1587.1 14 bp overlap

Motif ES_0h ES_0h-ZNF135_MA1587.1 14 bp overlap

ZNF213 2 datasets

Motif DE_12h DE_12h-ZNF213_MA2121.1 12 bp overlap

Motif ES_0h ES_0h-ZNF213_MA2121.1 12 bp overlap

ZNF316 1 dataset

ChIP K562 ENCFF281INV 75 bp overlap

ZNF335 2 datasets

ChIP HEK293 ENCFF784SLD 427 bp overlap

ChIP HEK293 ENCSR328SUD.ZNF335.HEK293 253 bp overlap

ZNF362 1 dataset

ChIP HEK293 ENCSR715QNO.ZNF362.HEK293 138 bp overlap

ZNF382 2 datasets

Motif DE_12h DE_12h-ZNF382_MA1594.1 24 bp overlap

Motif ES_0h ES_0h-ZNF382_MA1594.1 24 bp overlap

ZNF384 3 datasets

ChIP HEK293T ENCFF019DZX 160 bp overlap

ChIP HEK293T ENCSR882ICT.ZNF384.HEK293T 201 bp overlap

ChIP K562 ENCFF365NXQ 115 bp overlap

ZNF549 2 datasets

Motif DE_12h DE_12h-ZNF549_MA1728.2 8 bp overlap

Motif ES_0h ES_0h-ZNF549_MA1728.2 8 bp overlap

ZNF701 2 datasets

Motif DE_12h DE_12h-ZNF701_MA1987.2 17 bp overlap

Motif ES_0h ES_0h-ZNF701_MA1987.2 17 bp overlap

ZNF707 2 datasets

Motif DE_12h DE_12h-ZNF707_MA1715.1 15 bp overlap

Motif ES_0h ES_0h-ZNF707_MA1715.1 15 bp overlap