chr7 : 35,301,809 – 35,303,376

1,567 bp 85 TFs 3 linked genes

This 1.6 kb open chromatin element is linked to TBX20, ENSG00000291133, and DPY19L1 and is bound by 85 transcription factors.

Linked Genes

3 genes

Gene	Dist. to TSS	Distance	Link type
TBX20	48.3 kb	Distal	Multiome
ENSG00000291133	116.3 kb	Distal	Multiome
DPY19L1	264.4 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

85 transcription factors

ATF6 2 datasets

Motif DE_48h DE_48h-ATF6_MA1466.2 13 bp overlap

Motif DE_60h DE_60h-ATF6_MA1466.2 13 bp overlap

BACH2 2 datasets

Motif DE_48h DE_48h-BACH2_MA1470.2 19 bp overlap

Motif DE_60h DE_60h-BACH2_MA1470.2 19 bp overlap

CUX2 2 datasets

Motif DE_48h DE_48h-CUX2_MA0755.2 9 bp overlap

Motif DE_60h DE_60h-CUX2_MA0755.2 9 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF680YXW 247 bp overlap

Crx 1 dataset

Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap

DPRX 1 dataset

Motif DE_72h DE_72h-DPRX_MA1480.2 9 bp overlap

DUX4 1 dataset

Motif DE_72h DE_72h-DUX4_MA0468.1 11 bp overlap

Dmbx1 1 dataset

Motif DE_72h DE_72h-Dmbx1_MA0883.2 10 bp overlap

E2F7 2 datasets

Motif DE_60h DE_60h-E2F7_MA0758.1 14 bp overlap

Motif DE_72h DE_72h-E2F7_MA0758.1 14 bp overlap

EOMES 3 datasets

Motif DE_60h DE_60h-EOMES_MA0800.2 9 bp overlap

ChIP hESC GSE26097.EOMES.hESC 275 bp overlap

ChIP hESC GSE26097.EOMES.hESC 322 bp overlap

ETS1 1 dataset

ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 204 bp overlap

EWSR1-FLI1 2 datasets

Motif DE_48h DE_48h-EWSR1-FLI1_MA0149.1 18 bp overlap

Motif DE_60h DE_60h-EWSR1-FLI1_MA0149.1 18 bp overlap

FIGLA 1 dataset

Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap

FOXA1 8 datasets

ChIP MCF-7 GSE72249.FOXA1.MCF-7 248 bp overlap

ChIP MCF-7 GSE59530.FOXA1.MCF-7 139 bp overlap

ChIP MCF-7_DEX GSE72249.FOXA1.MCF-7_DEX 214 bp overlap

ChIP MCF-7_E2 GSE60270.FOXA1.MCF-7_E2 214 bp overlap

ChIP MCF-7_E2 GSE72249.FOXA1.MCF-7_E2 209 bp overlap

ChIP MCF-7_E2_TNF GSE59530.FOXA1.MCF-7_E2_TNF 184 bp overlap

ChIP MCF-7_TNF GSE59530.FOXA1.MCF-7_TNF 149 bp overlap

ChIP MCF-7_vehicle_ab2 GSE112969.FOXA1.MCF-7_vehicle_ab2 303 bp overlap

FOXA2 4 datasets

ChIP DE DE-FOXA2-1 1397 bp overlap

ChIP DE DE-FOXA2-2 709 bp overlap

ChIP DE DE-FOXA2-2 550 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 258 bp overlap

FOXE1 1 dataset

Motif DE_60h DE_60h-FOXE1_MA1487.3 12 bp overlap

FOXF1 2 datasets

ChIP GIST48 GSE106624.FOXF1.GIST48 223 bp overlap

ChIP GIST48_siETV1 GSE106624.FOXF1.GIST48_siETV1 182 bp overlap

FOXN3 1 dataset

Motif DE_60h DE_60h-FOXN3_MA1489.1 8 bp overlap

Foxl2 1 dataset

Motif DE_60h DE_60h-Foxl2_MA1607.2 10 bp overlap

GATA2 1 dataset

ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 284 bp overlap

GATA3 1 dataset

ChIP MCF-7_E2 GSE81510.GATA3.MCF-7_E2 173 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 1263 bp overlap

ChIP DE DE-GATA4-2 1567 bp overlap

ChIP foregut GSE117136.GATA4.foregut 465 bp overlap

GATA6 14 datasets

ChIP DE DE-GATA6-1 1491 bp overlap

ChIP DE DE-GATA6-2 1567 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 574 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 361 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 555 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 648 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 1067 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 1144 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 321 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 662 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 542 bp overlap

ChIP foregut GSE117136.GATA6.foregut 466 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 254 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 322 bp overlap

GSC 1 dataset

Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap

GSC2 1 dataset

Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap

Hnf1A 2 datasets

Motif DE_48h DE_48h-Hnf1A_MA1991.2 10 bp overlap

Motif DE_60h DE_60h-Hnf1A_MA1991.2 10 bp overlap

JUN 1 dataset

ChIP DE_D2 S54-DE-d2-JUN-exp2 339 bp overlap

MEIS1 2 datasets

Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap

Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap

MGA 1 dataset

Motif DE_60h DE_60h-MGA_MA0801.1 8 bp overlap

MGA::EVX1 1 dataset

Motif DE_60h DE_60h-MGAEVX1_MA1960.2 11 bp overlap

MSC 1 dataset

Motif DE_60h DE_60h-MSC_MA0665.1 10 bp overlap

MYB 1 dataset

Motif DE_72h DE_72h-MYB_MA0100.4 6 bp overlap

MYF6 1 dataset

Motif DE_60h DE_60h-MYF6_MA0667.1 10 bp overlap

MYOD1 1 dataset

Motif DE_60h DE_60h-MYOD1_MA0499.3 9 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 299 bp overlap

NFIB 2 datasets

Motif DE_48h DE_48h-NFIB_MA1643.2 17 bp overlap

Motif DE_60h DE_60h-NFIB_MA1643.2 17 bp overlap

NR1H2::RXRA 2 datasets

Motif DE_48h DE_48h-NR1H2RXRA_MA0115.1 17 bp overlap

Motif DE_60h DE_60h-NR1H2RXRA_MA0115.1 17 bp overlap

Nfatc2 2 datasets

Motif DE_48h DE_48h-Nfatc2_MA0152.3 8 bp overlap

Motif DE_60h DE_60h-Nfatc2_MA0152.3 8 bp overlap

OTX1 1 dataset

Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap

PBX1 1 dataset

Motif DE_72h DE_72h-PBX1_MA0070.2 9 bp overlap

PHOX2A 1 dataset

Motif DE_72h DE_72h-PHOX2A_MA0713.1 11 bp overlap

PHOX2B 1 dataset

Motif DE_72h DE_72h-PHOX2B_MA0681.3 12 bp overlap

PITX1 1 dataset

Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap

PITX2 1 dataset

Motif DE_72h DE_72h-PITX2_MA1547.2 8 bp overlap

PITX3 1 dataset

Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap

PKNOX2 1 dataset

Motif DE_60h DE_60h-PKNOX2_MA0783.1 12 bp overlap

POU5F1 1 dataset

Motif DE_60h DE_60h-POU5F1_MA1115.2 7 bp overlap

PROP1 1 dataset

Motif DE_72h DE_72h-PROP1_MA0715.1 11 bp overlap

Ptf1A 1 dataset

Motif DE_60h DE_60h-Ptf1A_MA1620.2 8 bp overlap

RHOXF1 1 dataset

Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 195 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 419 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 651 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 456 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 366 bp overlap

SMAD3 1 dataset

ChIP endoderm GSE29422.SMAD3.endoderm 196 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 285 bp overlap

SNAI2 1 dataset

Motif DE_60h DE_60h-SNAI2_MA0745.3 8 bp overlap

SNAI3 1 dataset

Motif DE_60h DE_60h-SNAI3_MA1559.2 9 bp overlap

SOX17 2 datasets

ChIP DE_D2 DED2-SOX17_Batch_II 292 bp overlap

ChIP DE_D2 DED2-SOX17_Batch_II 222 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 1227 bp overlap

SOX8 1 dataset

ChIP RH4_Entinostat-6H GSE116344.SOX8.RH4_Entinostat-6H 201 bp overlap

T 1 dataset

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 179 bp overlap

TBR1 1 dataset

Motif DE_60h DE_60h-TBR1_MA0802.2 9 bp overlap

TBX1 1 dataset

Motif DE_60h DE_60h-TBX1_MA0805.1 8 bp overlap

TBX15 1 dataset

Motif DE_60h DE_60h-TBX15_MA0803.1 8 bp overlap

TBX18 1 dataset

Motif DE_60h DE_60h-TBX18_MA1565.2 9 bp overlap

TBX2 1 dataset

Motif DE_60h DE_60h-TBX2_MA0688.2 9 bp overlap

TBX20 1 dataset

Motif DE_60h DE_60h-TBX20_MA0689.1 11 bp overlap

TBX21 1 dataset

Motif DE_60h DE_60h-TBX21_MA0690.3 10 bp overlap

TBX3 1 dataset

Motif DE_60h DE_60h-TBX3_MA1566.3 9 bp overlap

TBX4 1 dataset

Motif DE_60h DE_60h-TBX4_MA0806.1 8 bp overlap

TBX5 1 dataset

Motif DE_60h DE_60h-TBX5_MA0807.1 8 bp overlap

TCF7L1 2 datasets

Motif DE_48h DE_48h-TCF7L1_MA1421.1 12 bp overlap

Motif DE_60h DE_60h-TCF7L1_MA1421.1 12 bp overlap

TCF7L2 1 dataset

Motif DE_72h DE_72h-TCF7L2_MA0523.2 9 bp overlap

TGIF1 1 dataset

Motif DE_60h DE_60h-TGIF1_MA0796.1 12 bp overlap

TGIF2 1 dataset

Motif DE_60h DE_60h-TGIF2_MA0797.1 12 bp overlap

TGIF2LX 1 dataset

Motif DE_60h DE_60h-TGIF2LX_MA1571.1 12 bp overlap

TGIF2LY 1 dataset

Motif DE_60h DE_60h-TGIF2LY_MA1572.1 12 bp overlap

Tbx6 1 dataset

Motif DE_60h DE_60h-Tbx6_MA1567.3 9 bp overlap

Tcf21 1 dataset

Motif DE_60h DE_60h-Tcf21_MA0832.2 10 bp overlap

ZBTB18 1 dataset

Motif DE_60h DE_60h-ZBTB18_MA0698.2 11 bp overlap

ZEB1 1 dataset

Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap

ZIM3 1 dataset

Motif DE_60h DE_60h-ZIM3_MA1709.2 11 bp overlap

ZNF24 1 dataset

Motif DE_72h DE_72h-ZNF24_MA1124.1 13 bp overlap

ZNF418 1 dataset

Motif DE_72h DE_72h-ZNF418_MA1980.1 15 bp overlap

ZNF558 1 dataset

Motif DE_72h DE_72h-ZNF558_MA2335.1 29 bp overlap