chr7 : 40,120,029 – 40,120,539
510 bp 58 TFs 3 linked genes
This 510 bp open chromatin element is linked to MPLKIP, SUGCT, and CDK13 and is bound by 58 transcription factors.
Linked Genes
3 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
MPLKIP 14.3 kb Distal Multiome
SUGCT 14.7 kb Distal Multiome
CDK13 122.1 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr7:40,115,029 – 40,125,539
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
58 transcription factors
Source
Cell type
CHD7 1 dataset
ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 102 bp overlap
CREB1 4 datasets
Motif DE_36h DE_36h-CREB1_MA0018.5 8 bp overlap
Motif DE_48h DE_48h-CREB1_MA0018.5 8 bp overlap
Motif DE_60h DE_60h-CREB1_MA0018.5 8 bp overlap
Motif DE_72h DE_72h-CREB1_MA0018.5 8 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 166 bp overlap
ERF::FOXI1 3 datasets
Motif DE_36h DE_36h-ERFFOXI1_MA1935.2 10 bp overlap
Motif DE_48h DE_48h-ERFFOXI1_MA1935.2 10 bp overlap
Motif DE_72h DE_72h-ERFFOXI1_MA1935.2 10 bp overlap
ETS1 1 dataset
ChIP HUVEC-C_VEGF_1H GSE41166.ETS1.HUVEC-C_VEGF_1H 114 bp overlap
ETV2::FOXI1 3 datasets
Motif DE_36h DE_36h-ETV2FOXI1_MA1942.2 11 bp overlap
Motif DE_48h DE_48h-ETV2FOXI1_MA1942.2 11 bp overlap
Motif DE_72h DE_72h-ETV2FOXI1_MA1942.2 11 bp overlap
EWSR1-FLI1 2 datasets
Motif DE_60h DE_60h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_72h DE_72h-EWSR1-FLI1_MA0149.1 18 bp overlap
Ebf4 1 dataset
Motif DE_36h DE_36h-Ebf4_MA2122.1 11 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 354 bp overlap
ChIP DE DE-FOXA2-2 331 bp overlap
GABPA 1 dataset
ChIP VCaP GSE49091.GABPA.VCaP 54 bp overlap
GATA4 7 datasets
ChIP DE DE-GATA4-1 508 bp overlap
ChIP DE DE-GATA4-2 492 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 310 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 352 bp overlap
GATA5 3 datasets
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 15 datasets
ChIP DE DE-GATA6-1 501 bp overlap
ChIP DE DE-GATA6-2 485 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 488 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 489 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 436 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 487 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 500 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 479 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 426 bp overlap
ChIP foregut GSE117136.GATA6.foregut 394 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 254 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 278 bp overlap
Gata3 3 datasets
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
HSF1 1 dataset
ChIP MO91 GSE45852.HSF1.MO91 176 bp overlap
Hand1::Tcf3 3 datasets
Motif DE_36h DE_36h-Hand1Tcf3_MA0092.2 9 bp overlap
Motif DE_60h DE_60h-Hand1Tcf3_MA0092.2 9 bp overlap
Motif DE_72h DE_72h-Hand1Tcf3_MA0092.2 9 bp overlap
IKZF1 3 datasets
Motif DE_36h DE_36h-IKZF1_MA1508.2 8 bp overlap
Motif DE_48h DE_48h-IKZF1_MA1508.2 8 bp overlap
Motif DE_72h DE_72h-IKZF1_MA1508.2 8 bp overlap
IRF6 3 datasets
Motif DE_36h DE_36h-IRF6_MA1509.1 9 bp overlap
Motif DE_48h DE_48h-IRF6_MA1509.1 9 bp overlap
Motif DE_72h DE_72h-IRF6_MA1509.1 9 bp overlap
Irf1 3 datasets
Motif DE_36h DE_36h-Irf1_MA0050.4 11 bp overlap
Motif DE_60h DE_60h-Irf1_MA0050.4 11 bp overlap
Motif DE_72h DE_72h-Irf1_MA0050.4 11 bp overlap
MAX 1 dataset
ChIP MDA-MB-468 GSE81381.MAX.MDA-MB-468 65 bp overlap
MEIS1 7 datasets
Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap
Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
NFATC3 5 datasets
Motif DE_36h DE_36h-NFATC3_MA0625.3 6 bp overlap
Motif DE_36h DE_36h-NFATC3_MA0625.3 6 bp overlap
Motif DE_48h DE_48h-NFATC3_MA0625.3 6 bp overlap
Motif DE_60h DE_60h-NFATC3_MA0625.3 6 bp overlap
Motif DE_72h DE_72h-NFATC3_MA0625.3 6 bp overlap
NR2C2 4 datasets
Motif DE_36h DE_36h-NR2C2_MA0504.2 14 bp overlap
Motif DE_48h DE_48h-NR2C2_MA0504.2 14 bp overlap
Motif DE_60h DE_60h-NR2C2_MA0504.2 14 bp overlap
Motif DE_72h DE_72h-NR2C2_MA0504.2 14 bp overlap
Nfat5 4 datasets
Motif DE_36h DE_36h-Nfat5_MA0606.3 8 bp overlap
Motif DE_48h DE_48h-Nfat5_MA0606.3 8 bp overlap
Motif DE_60h DE_60h-Nfat5_MA0606.3 8 bp overlap
Motif DE_72h DE_72h-Nfat5_MA0606.3 8 bp overlap
Nfatc1 5 datasets
Motif DE_36h DE_36h-Nfatc1_MA0624.3 6 bp overlap
Motif DE_36h DE_36h-Nfatc1_MA0624.3 6 bp overlap
Motif DE_48h DE_48h-Nfatc1_MA0624.3 6 bp overlap
Motif DE_60h DE_60h-Nfatc1_MA0624.3 6 bp overlap
Motif DE_72h DE_72h-Nfatc1_MA0624.3 6 bp overlap
Nfatc2 1 dataset
Motif DE_36h DE_36h-Nfatc2_MA0152.3 8 bp overlap
OSR1 2 datasets
Motif DE_36h DE_36h-OSR1_MA1542.2 8 bp overlap
Motif DE_60h DE_60h-OSR1_MA1542.2 8 bp overlap
OSR2 2 datasets
Motif DE_36h DE_36h-OSR2_MA1646.2 8 bp overlap
Motif DE_60h DE_60h-OSR2_MA1646.2 8 bp overlap
PBX3 3 datasets
Motif DE_36h DE_36h-PBX3_MA1114.2 11 bp overlap
Motif DE_48h DE_48h-PBX3_MA1114.2 11 bp overlap
Motif DE_72h DE_72h-PBX3_MA1114.2 11 bp overlap
PHOX2B 4 datasets
Motif DE_36h DE_36h-PHOX2B_MA0681.3 12 bp overlap
Motif DE_48h DE_48h-PHOX2B_MA0681.3 12 bp overlap
Motif DE_60h DE_60h-PHOX2B_MA0681.3 12 bp overlap
Motif DE_72h DE_72h-PHOX2B_MA0681.3 12 bp overlap
PKNOX1 3 datasets
Motif DE_36h DE_36h-PKNOX1_MA0782.3 10 bp overlap
Motif DE_48h DE_48h-PKNOX1_MA0782.3 10 bp overlap
Motif DE_72h DE_72h-PKNOX1_MA0782.3 10 bp overlap
PROP1 4 datasets
Motif DE_36h DE_36h-PROP1_MA0715.1 11 bp overlap
Motif DE_48h DE_48h-PROP1_MA0715.1 11 bp overlap
Motif DE_60h DE_60h-PROP1_MA0715.1 11 bp overlap
Motif DE_72h DE_72h-PROP1_MA0715.1 11 bp overlap
RXRA::VDR 3 datasets
Motif DE_36h DE_36h-RXRAVDR_MA0074.1 15 bp overlap
Motif DE_48h DE_48h-RXRAVDR_MA0074.1 15 bp overlap
Motif DE_72h DE_72h-RXRAVDR_MA0074.1 15 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 357 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 371 bp overlap
ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 510 bp overlap
SMAD2_3 3 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 320 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 467 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 353 bp overlap
SOX21 2 datasets
Motif DE_36h DE_36h-SOX21_MA0866.1 15 bp overlap
Motif DE_60h DE_60h-SOX21_MA0866.1 15 bp overlap
STAT1::STAT2 3 datasets
Motif DE_36h DE_36h-STAT1STAT2_MA0517.2 13 bp overlap
Motif DE_60h DE_60h-STAT1STAT2_MA0517.2 13 bp overlap
Motif DE_72h DE_72h-STAT1STAT2_MA0517.2 13 bp overlap
STAT3 7 datasets
Motif DE_36h DE_36h-STAT3_MA0144.3 9 bp overlap
Motif DE_36h DE_36h-STAT3_MA0144.3 9 bp overlap
Motif DE_48h DE_48h-STAT3_MA0144.3 9 bp overlap
Motif DE_60h DE_60h-STAT3_MA0144.3 9 bp overlap
Motif DE_60h DE_60h-STAT3_MA0144.3 9 bp overlap
Motif DE_72h DE_72h-STAT3_MA0144.3 9 bp overlap
Motif DE_72h DE_72h-STAT3_MA0144.3 9 bp overlap
Sox11 3 datasets
Motif DE_36h DE_36h-Sox11_MA0869.3 8 bp overlap
Motif DE_48h DE_48h-Sox11_MA0869.3 8 bp overlap
Motif DE_72h DE_72h-Sox11_MA0869.3 8 bp overlap
Sox17 3 datasets
Motif DE_36h DE_36h-Sox17_MA0078.3 10 bp overlap
Motif DE_48h DE_48h-Sox17_MA0078.3 10 bp overlap
Motif DE_72h DE_72h-Sox17_MA0078.3 10 bp overlap
Sox6 3 datasets
Motif DE_36h DE_36h-Sox6_MA0515.1 10 bp overlap
Motif DE_48h DE_48h-Sox6_MA0515.1 10 bp overlap
Motif DE_72h DE_72h-Sox6_MA0515.1 10 bp overlap
Sox7 3 datasets
Motif DE_36h DE_36h-Sox7_MA2095.1 10 bp overlap
Motif DE_48h DE_48h-Sox7_MA2095.1 10 bp overlap
Motif DE_72h DE_72h-Sox7_MA2095.1 10 bp overlap
Stat2 3 datasets
Motif DE_36h DE_36h-Stat2_MA1623.2 10 bp overlap
Motif DE_60h DE_60h-Stat2_MA1623.2 10 bp overlap
Motif DE_72h DE_72h-Stat2_MA1623.2 10 bp overlap
TBX18 4 datasets
Motif DE_36h DE_36h-TBX18_MA1565.2 9 bp overlap
Motif DE_48h DE_48h-TBX18_MA1565.2 9 bp overlap
Motif DE_60h DE_60h-TBX18_MA1565.2 9 bp overlap
Motif DE_72h DE_72h-TBX18_MA1565.2 9 bp overlap
TRPS1 3 datasets
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
VEZF1 2 datasets
Motif DE_36h DE_36h-VEZF1_MA1578.2 6 bp overlap
Motif DE_72h DE_72h-VEZF1_MA1578.2 6 bp overlap
ZBTB32 2 datasets
Motif DE_36h DE_36h-ZBTB32_MA1580.1 10 bp overlap
Motif DE_60h DE_60h-ZBTB32_MA1580.1 10 bp overlap
ZBTB7B 2 datasets
Motif DE_36h DE_36h-ZBTB7B_MA0694.2 10 bp overlap
Motif DE_72h DE_72h-ZBTB7B_MA0694.2 10 bp overlap
ZNF184 3 datasets
Motif DE_36h DE_36h-ZNF184_MA2120.1 13 bp overlap
Motif DE_60h DE_60h-ZNF184_MA2120.1 13 bp overlap
Motif DE_72h DE_72h-ZNF184_MA2120.1 13 bp overlap
ZNF257 4 datasets
Motif DE_36h DE_36h-ZNF257_MA1710.2 10 bp overlap
Motif DE_48h DE_48h-ZNF257_MA1710.2 10 bp overlap
Motif DE_60h DE_60h-ZNF257_MA1710.2 10 bp overlap
Motif DE_72h DE_72h-ZNF257_MA1710.2 10 bp overlap
ZNF354A 3 datasets
Motif DE_36h DE_36h-ZNF354A_MA1978.2 20 bp overlap
Motif DE_60h DE_60h-ZNF354A_MA1978.2 20 bp overlap
Motif DE_72h DE_72h-ZNF354A_MA1978.2 20 bp overlap
ZNF382 3 datasets
Motif DE_36h DE_36h-ZNF382_MA1594.1 24 bp overlap
Motif DE_48h DE_48h-ZNF382_MA1594.1 24 bp overlap
Motif DE_72h DE_72h-ZNF382_MA1594.1 24 bp overlap
ZNF384 3 datasets
Motif DE_36h DE_36h-ZNF384_MA1125.2 8 bp overlap
Motif DE_60h DE_60h-ZNF384_MA1125.2 8 bp overlap
Motif DE_72h DE_72h-ZNF384_MA1125.2 8 bp overlap
ZNF460 2 datasets
Motif DE_36h DE_36h-ZNF460_MA1596.1 16 bp overlap
Motif DE_60h DE_60h-ZNF460_MA1596.1 16 bp overlap
ZNF530 3 datasets
Motif DE_36h DE_36h-ZNF530_MA1981.2 14 bp overlap
Motif DE_48h DE_48h-ZNF530_MA1981.2 14 bp overlap
Motif DE_72h DE_72h-ZNF530_MA1981.2 14 bp overlap
ZNF674 1 dataset
ChIP HEK293T GSE78099.ZNF674.HEK293T 189 bp overlap
ZNF677 3 datasets
Motif DE_36h DE_36h-ZNF677_MA2101.1 12 bp overlap
Motif DE_48h DE_48h-ZNF677_MA2101.1 12 bp overlap
Motif DE_72h DE_72h-ZNF677_MA2101.1 12 bp overlap
ZNF770 2 datasets
Motif DE_36h DE_36h-ZNF770_MA2099.1 8 bp overlap
Motif DE_60h DE_60h-ZNF770_MA2099.1 8 bp overlap
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