chr7 : 137,752,833 – 137,753,611
778 bp 70 TFs 2 linked genes
This 778 bp open chromatin element is linked to DGKI and CREB3L2 and is bound by 70 transcription factors.
Linked Genes
2 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
DGKI 93.8 kb Distal Multiome
CREB3L2 248.8 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr7:137,747,833 – 137,758,611
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
70 transcription factors
Source
Cell type
Arid3a 4 datasets
Motif DE_12h DE_12h-Arid3a_MA0151.1 6 bp overlap
Motif DE_24h DE_24h-Arid3a_MA0151.1 6 bp overlap
Motif DE_36h DE_36h-Arid3a_MA0151.1 6 bp overlap
Motif DE_48h DE_48h-Arid3a_MA0151.1 6 bp overlap
Ascl2 4 datasets
Motif DE_12h DE_12h-Ascl2_MA0816.1 10 bp overlap
Motif DE_24h DE_24h-Ascl2_MA0816.1 10 bp overlap
Motif DE_36h DE_36h-Ascl2_MA0816.1 10 bp overlap
Motif DE_48h DE_48h-Ascl2_MA0816.1 10 bp overlap
BCOR 1 dataset
ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 149 bp overlap
BRD4 1 dataset
ChIP NCI-H1963_shASXL3 GSE145028.BRD4.NCI-H1963_shASXL3 263 bp overlap
CTCF 4 datasets
Motif DE_12h DE_12h-CTCF_MA1929.2 31 bp overlap
Motif DE_24h DE_24h-CTCF_MA1929.2 31 bp overlap
Motif DE_36h DE_36h-CTCF_MA1929.2 31 bp overlap
Motif DE_48h DE_48h-CTCF_MA1929.2 31 bp overlap
Crx 4 datasets
Motif DE_12h DE_12h-Crx_MA0467.3 6 bp overlap
Motif DE_24h DE_24h-Crx_MA0467.3 6 bp overlap
Motif DE_36h DE_36h-Crx_MA0467.3 6 bp overlap
Motif DE_48h DE_48h-Crx_MA0467.3 6 bp overlap
DPRX 4 datasets
Motif DE_12h DE_12h-DPRX_MA1480.2 9 bp overlap
Motif DE_24h DE_24h-DPRX_MA1480.2 9 bp overlap
Motif DE_36h DE_36h-DPRX_MA1480.2 9 bp overlap
Motif DE_48h DE_48h-DPRX_MA1480.2 9 bp overlap
EZH2 1 dataset
ChIP PC-9 ENCSR793USK.EZH2.PC-9 611 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 428 bp overlap
ChIP DE DE-FOXA2-2 465 bp overlap
FOXH1 5 datasets
Motif DE_12h DE_12h-FOXH1_MA0479.2 8 bp overlap
Motif DE_12h DE_12h-FOXH1_MA0479.2 8 bp overlap
Motif DE_24h DE_24h-FOXH1_MA0479.2 8 bp overlap
Motif DE_36h DE_36h-FOXH1_MA0479.2 8 bp overlap
Motif DE_48h DE_48h-FOXH1_MA0479.2 8 bp overlap
GATA4 2 datasets
ChIP DE DE-GATA4-1 502 bp overlap
ChIP DE DE-GATA4-2 518 bp overlap
GATA5 1 dataset
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
GATA6 11 datasets
ChIP DE DE-GATA6-1 563 bp overlap
ChIP DE DE-GATA6-2 689 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 331 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 359 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 556 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 530 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 530 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 579 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 371 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 262 bp overlap
GLIS1 2 datasets
ChIP HEK293 ENCFF299RSE 312 bp overlap
ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 503 bp overlap
GSC 4 datasets
Motif DE_12h DE_12h-GSC_MA0648.2 6 bp overlap
Motif DE_24h DE_24h-GSC_MA0648.2 6 bp overlap
Motif DE_36h DE_36h-GSC_MA0648.2 6 bp overlap
Motif DE_48h DE_48h-GSC_MA0648.2 6 bp overlap
GSC2 4 datasets
Motif DE_12h DE_12h-GSC2_MA0891.2 6 bp overlap
Motif DE_24h DE_24h-GSC2_MA0891.2 6 bp overlap
Motif DE_36h DE_36h-GSC2_MA0891.2 6 bp overlap
Motif DE_48h DE_48h-GSC2_MA0891.2 6 bp overlap
Gata3 1 dataset
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
HSF4 4 datasets
Motif DE_12h DE_12h-HSF4_MA0771.1 13 bp overlap
Motif DE_24h DE_24h-HSF4_MA0771.1 13 bp overlap
Motif DE_36h DE_36h-HSF4_MA0771.1 13 bp overlap
Motif DE_48h DE_48h-HSF4_MA0771.1 13 bp overlap
Hand1::Tcf3 4 datasets
Motif DE_12h DE_12h-Hand1Tcf3_MA0092.2 9 bp overlap
Motif DE_24h DE_24h-Hand1Tcf3_MA0092.2 9 bp overlap
Motif DE_36h DE_36h-Hand1Tcf3_MA0092.2 9 bp overlap
Motif DE_48h DE_48h-Hand1Tcf3_MA0092.2 9 bp overlap
JUN 3 datasets
ChIP DE_D2 S02-DE-d2-JUN-exp1 348 bp overlap
ChIP DE_D2 S54-DE-d2-JUN-exp2 264 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 437 bp overlap
LIN54 4 datasets
Motif DE_12h DE_12h-LIN54_MA0619.2 7 bp overlap
Motif DE_24h DE_24h-LIN54_MA0619.2 7 bp overlap
Motif DE_36h DE_36h-LIN54_MA0619.2 7 bp overlap
Motif DE_48h DE_48h-LIN54_MA0619.2 7 bp overlap
MAX 1 dataset
ChIP NCI-H128 GSE41105.MAX.NCI-H128 337 bp overlap
MED26 1 dataset
ChIP HEK293T GSE121024.MED26.HEK293T 187 bp overlap
MXI1 3 datasets
Motif DE_12h DE_12h-MXI1_MA1108.3 6 bp overlap
Motif DE_24h DE_24h-MXI1_MA1108.3 6 bp overlap
Motif DE_36h DE_36h-MXI1_MA1108.3 6 bp overlap
MYB 4 datasets
Motif DE_12h DE_12h-MYB_MA0100.4 6 bp overlap
Motif DE_24h DE_24h-MYB_MA0100.4 6 bp overlap
Motif DE_36h DE_36h-MYB_MA0100.4 6 bp overlap
Motif DE_48h DE_48h-MYB_MA0100.4 6 bp overlap
MZF1 4 datasets
Motif DE_12h DE_12h-MZF1_MA0056.3 8 bp overlap
Motif DE_24h DE_24h-MZF1_MA0056.3 8 bp overlap
Motif DE_36h DE_36h-MZF1_MA0056.3 8 bp overlap
Motif DE_48h DE_48h-MZF1_MA0056.3 8 bp overlap
Mecom 1 dataset
Motif DE_36h DE_36h-Mecom_MA0029.2 11 bp overlap
NANOG 1 dataset
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 589 bp overlap
NEUROD1 3 datasets
ChIP D283-Med GSE92582.NEUROD1.D283-Med 224 bp overlap
ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 612 bp overlap
ChIP D341-Med_shNEUROD1-1154 GSE92582.NEUROD1.D341-Med_shNEUROD1-1154 714 bp overlap
NFIA 1 dataset
Motif DE_36h DE_36h-NFIA_MA0670.2 6 bp overlap
NFIX 1 dataset
Motif DE_36h DE_36h-NFIX_MA0671.2 6 bp overlap
OTX1 4 datasets
Motif DE_12h DE_12h-OTX1_MA0711.2 6 bp overlap
Motif DE_24h DE_24h-OTX1_MA0711.2 6 bp overlap
Motif DE_36h DE_36h-OTX1_MA0711.2 6 bp overlap
Motif DE_48h DE_48h-OTX1_MA0711.2 6 bp overlap
PITX1 4 datasets
Motif DE_12h DE_12h-PITX1_MA0682.3 6 bp overlap
Motif DE_24h DE_24h-PITX1_MA0682.3 6 bp overlap
Motif DE_36h DE_36h-PITX1_MA0682.3 6 bp overlap
Motif DE_48h DE_48h-PITX1_MA0682.3 6 bp overlap
PITX3 5 datasets
Motif DE_12h DE_12h-PITX3_MA0714.2 6 bp overlap
Motif DE_24h DE_24h-PITX3_MA0714.2 6 bp overlap
Motif DE_36h DE_36h-PITX3_MA0714.2 6 bp overlap
Motif DE_48h DE_48h-PITX3_MA0714.2 6 bp overlap
ChIP SH-SY5Y GSE93275.PITX3.SH-SY5Y 587 bp overlap
POU5F1 1 dataset
ChIP DE_D1 DED1-OCT4_Batch_II 529 bp overlap
RHOXF1 4 datasets
Motif DE_12h DE_12h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_24h DE_24h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_36h DE_36h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_48h DE_48h-RHOXF1_MA0719.2 6 bp overlap
SETDB1 2 datasets
ChIP HEK293 ENCSR348AGV.SETDB1.HEK293 355 bp overlap
ChIP U2OS ENCSR000EYD.SETDB1.U2OS 361 bp overlap
SIX2 6 datasets
Motif DE_12h DE_12h-SIX2_MA1119.2 11 bp overlap
Motif DE_24h DE_24h-SIX2_MA1119.2 11 bp overlap
Motif DE_36h DE_36h-SIX2_MA1119.2 11 bp overlap
ChIP HEK GSE73865.SIX2.HEK 322 bp overlap
ChIP kidney_fetal_16w GSE75948.SIX2.kidney_fetal_16w 256 bp overlap
ChIP kidney_fetal_17w GSE75948.SIX2.kidney_fetal_17w 330 bp overlap
SMAD2 6 datasets
Motif DE_12h DE_12h-SMAD2_MA1964.2 6 bp overlap
Motif DE_24h DE_24h-SMAD2_MA1964.2 6 bp overlap
Motif DE_36h DE_36h-SMAD2_MA1964.2 6 bp overlap
Motif DE_48h DE_48h-SMAD2_MA1964.2 6 bp overlap
ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 608 bp overlap
ChIP hESC_activinA_15h GSE99202.SMAD2.hESC_activinA_15h 344 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 654 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 738 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 641 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 747 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 778 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 694 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 769 bp overlap
SMAD3 2 datasets
ChIP BG03_DIFF_2H GSE36578.SMAD3.BG03_DIFF_2H 178 bp overlap
ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 210 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 218 bp overlap
SMARCA4 2 datasets
ChIP NGP_ARID1A-mut2 GSE134626.SMARCA4.NGP_ARID1A-mut2 374 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 372 bp overlap
SMARCC1 1 dataset
ChIP hiPSC GSE124903.SMARCC1.hiPSC 210 bp overlap
SOX10 2 datasets
Motif DE_12h DE_12h-SOX10_MA0442.3 6 bp overlap
Motif DE_36h DE_36h-SOX10_MA0442.3 6 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 200 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 345 bp overlap
SOX4 2 datasets
Motif DE_12h DE_12h-SOX4_MA0867.3 8 bp overlap
Motif DE_36h DE_36h-SOX4_MA0867.3 8 bp overlap
SOX8 1 dataset
ChIP RH4_Entinostat-6H GSE116344.SOX8.RH4_Entinostat-6H 208 bp overlap
Smad4 4 datasets
Motif DE_12h DE_12h-Smad4_MA1153.2 7 bp overlap
Motif DE_24h DE_24h-Smad4_MA1153.2 7 bp overlap
Motif DE_36h DE_36h-Smad4_MA1153.2 7 bp overlap
Motif DE_48h DE_48h-Smad4_MA1153.2 7 bp overlap
Sox17 2 datasets
Motif DE_12h DE_12h-Sox17_MA0078.3 10 bp overlap
Motif DE_36h DE_36h-Sox17_MA0078.3 10 bp overlap
Sox5 2 datasets
Motif DE_12h DE_12h-Sox5_MA0087.3 8 bp overlap
Motif DE_36h DE_36h-Sox5_MA0087.3 8 bp overlap
Sox7 2 datasets
Motif DE_12h DE_12h-Sox7_MA2095.1 10 bp overlap
Motif DE_36h DE_36h-Sox7_MA2095.1 10 bp overlap
Spz1 1 dataset
Motif DE_12h DE_12h-Spz1_MA0111.1 11 bp overlap
TCF7L2 2 datasets
ChIP HEK293 ENCFF513JQN 505 bp overlap
ChIP HEK293 ENCSR000EUY.TCF7L2.HEK293 282 bp overlap
THAP1 2 datasets
Motif DE_12h DE_12h-THAP1_MA0597.3 8 bp overlap
Motif DE_24h DE_24h-THAP1_MA0597.3 8 bp overlap
TRIM28 2 datasets
ChIP HEK293 ENCFF582MWI 563 bp overlap
ChIP HEK293 ENCSR000EUZ.TRIM28.HEK293 408 bp overlap
TRPS1 1 dataset
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
ZBTB24 4 datasets
Motif DE_12h DE_12h-ZBTB24_MA2330.1 10 bp overlap
Motif DE_24h DE_24h-ZBTB24_MA2330.1 10 bp overlap
Motif DE_36h DE_36h-ZBTB24_MA2330.1 10 bp overlap
Motif DE_48h DE_48h-ZBTB24_MA2330.1 10 bp overlap
ZFP3 1 dataset
ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR581GUY.ZFP3.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 80 bp overlap
ZKSCAN3 4 datasets
Motif DE_12h DE_12h-ZKSCAN3_MA1973.2 14 bp overlap
Motif DE_24h DE_24h-ZKSCAN3_MA1973.2 14 bp overlap
Motif DE_36h DE_36h-ZKSCAN3_MA1973.2 14 bp overlap
Motif DE_48h DE_48h-ZKSCAN3_MA1973.2 14 bp overlap
ZNF143 1 dataset
ChIP FLP143HA_T0 GSE39263.ZNF143.FLP143HA_T0 149 bp overlap
ZNF331 1 dataset
Motif DE_36h DE_36h-ZNF331_MA1726.2 10 bp overlap
ZNF354C 4 datasets
Motif DE_12h DE_12h-ZNF354C_MA0130.1 6 bp overlap
Motif DE_24h DE_24h-ZNF354C_MA0130.1 6 bp overlap
Motif DE_36h DE_36h-ZNF354C_MA0130.1 6 bp overlap
Motif DE_48h DE_48h-ZNF354C_MA0130.1 6 bp overlap
ZNF454 4 datasets
Motif DE_12h DE_12h-ZNF454_MA1712.2 17 bp overlap
Motif DE_24h DE_24h-ZNF454_MA1712.2 17 bp overlap
Motif DE_36h DE_36h-ZNF454_MA1712.2 17 bp overlap
Motif DE_48h DE_48h-ZNF454_MA1712.2 17 bp overlap
ZNF574 1 dataset
Motif DE_12h DE_12h-ZNF574_MA1982.2 14 bp overlap
ZNF610 1 dataset
Motif DE_12h DE_12h-ZNF610_MA1713.2 10 bp overlap
ZNF708 2 datasets
Motif DE_12h DE_12h-ZNF708_MA1730.2 9 bp overlap
Motif DE_24h DE_24h-ZNF708_MA1730.2 9 bp overlap
ZSCAN16 1 dataset
Motif DE_36h DE_36h-ZSCAN16_MA2100.1 18 bp overlap
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