chr8 : 48,159,677 – 48,160,187
510 bp 52 TFs 3 linked genes
This 510 bp open chromatin element is linked to UBE2V2, MCM4, and PRKDC and is bound by 52 transcription factors.
Linked Genes
3 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
UBE2V2 151.4 kb Distal Multiome
MCM4 198.9 kb Distal Multiome
PRKDC 199.7 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr8:48,154,677 – 48,165,187
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
52 transcription factors
Source
Cell type
Ahr::Arnt 4 datasets
Motif DE_48h DE_48h-AhrArnt_MA0006.2 5 bp overlap
Motif DE_60h DE_60h-AhrArnt_MA0006.2 5 bp overlap
Motif DE_60h DE_60h-AhrArnt_MA0006.2 5 bp overlap
Motif DE_72h DE_72h-AhrArnt_MA0006.2 5 bp overlap
BARX2 3 datasets
Motif DE_48h DE_48h-BARX2_MA1471.2 9 bp overlap
Motif DE_60h DE_60h-BARX2_MA1471.2 9 bp overlap
Motif DE_72h DE_72h-BARX2_MA1471.2 9 bp overlap
Cebpa 4 datasets
ChIP BLaER1 ENCFF031ISE 82 bp overlap
ChIP BLaER1 ENCFF031ISE 88 bp overlap
ChIP BLaER1 ENCFF274GAT 265 bp overlap
ChIP BLaER1 ENCFF364PUR 268 bp overlap
Crx 3 datasets
Motif DE_48h DE_48h-Crx_MA0467.3 6 bp overlap
Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap
Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap
EBF1 3 datasets
Motif DE_48h DE_48h-EBF1_MA0154.5 11 bp overlap
Motif DE_60h DE_60h-EBF1_MA0154.5 11 bp overlap
Motif DE_72h DE_72h-EBF1_MA0154.5 11 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 186 bp overlap
Ebf4 3 datasets
Motif DE_48h DE_48h-Ebf4_MA2122.1 11 bp overlap
Motif DE_60h DE_60h-Ebf4_MA2122.1 11 bp overlap
Motif DE_72h DE_72h-Ebf4_MA2122.1 11 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 379 bp overlap
ChIP DE DE-FOXA2-2 370 bp overlap
GATA2 5 datasets
Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
Motif DE_72h DE_72h-GATA2_MA0036.4 7 bp overlap
ChIP Hep-G2 ENCSR897LDT.GATA2.Hep-G2 278 bp overlap
ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 339 bp overlap
GATA3 1 dataset
ChIP T47D-A1-2_EtOH GSE112491.GATA3.T47D-A1-2_EtOH 69 bp overlap
GATA4 8 datasets
ChIP DE DE-GATA4-1 362 bp overlap
ChIP DE DE-GATA4-2 400 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 317 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 285 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 272 bp overlap
GATA5 3 datasets
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 12 datasets
ChIP DE DE-GATA6-1 343 bp overlap
ChIP DE DE-GATA6-2 405 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 257 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 376 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 301 bp overlap
ChIP foregut GSE117136.GATA6.foregut 338 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 348 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 274 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 228 bp overlap
GSC 3 datasets
Motif DE_48h DE_48h-GSC_MA0648.2 6 bp overlap
Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap
Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap
GSC2 3 datasets
Motif DE_48h DE_48h-GSC2_MA0891.2 6 bp overlap
Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap
Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap
Gata3 3 datasets
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
HAND2 1 dataset
ChIP Kelly GSE94822.HAND2.Kelly 154 bp overlap
HOXA3 1 dataset
ChIP Hep-G2 ENCSR999JKC.HOXA3.Hep-G2 120 bp overlap
IRF2 3 datasets
Motif DE_48h DE_48h-IRF2_MA0051.2 16 bp overlap
Motif DE_60h DE_60h-IRF2_MA0051.2 16 bp overlap
Motif DE_72h DE_72h-IRF2_MA0051.2 16 bp overlap
IRF7 3 datasets
Motif DE_48h DE_48h-IRF7_MA0772.2 13 bp overlap
Motif DE_60h DE_60h-IRF7_MA0772.2 13 bp overlap
Motif DE_72h DE_72h-IRF7_MA0772.2 13 bp overlap
Irf1 3 datasets
Motif DE_48h DE_48h-Irf1_MA0050.4 11 bp overlap
Motif DE_60h DE_60h-Irf1_MA0050.4 11 bp overlap
Motif DE_72h DE_72h-Irf1_MA0050.4 11 bp overlap
KLF9 3 datasets
Motif DE_48h DE_48h-KLF9_MA1107.3 11 bp overlap
Motif DE_60h DE_60h-KLF9_MA1107.3 11 bp overlap
Motif DE_72h DE_72h-KLF9_MA1107.3 11 bp overlap
MGA::EVX1 3 datasets
Motif DE_48h DE_48h-MGAEVX1_MA1960.2 11 bp overlap
Motif DE_60h DE_60h-MGAEVX1_MA1960.2 11 bp overlap
Motif DE_72h DE_72h-MGAEVX1_MA1960.2 11 bp overlap
MYCN 1 dataset
ChIP Kelly GSE94822.MYCN.Kelly 218 bp overlap
NR1D1 1 dataset
Motif DE_48h DE_48h-NR1D1_MA1531.2 14 bp overlap
NR4A1 1 dataset
Motif DE_60h DE_60h-NR4A1_MA1112.3 8 bp overlap
NR4A2 1 dataset
Motif DE_60h DE_60h-NR4A2_MA0160.3 8 bp overlap
OTX1 3 datasets
Motif DE_48h DE_48h-OTX1_MA0711.2 6 bp overlap
Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap
Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap
OTX2 3 datasets
Motif DE_48h DE_48h-OTX2_MA0712.3 7 bp overlap
Motif DE_60h DE_60h-OTX2_MA0712.3 7 bp overlap
Motif DE_72h DE_72h-OTX2_MA0712.3 7 bp overlap
PBX3 2 datasets
Motif DE_48h DE_48h-PBX3_MA1114.2 11 bp overlap
Motif DE_72h DE_72h-PBX3_MA1114.2 11 bp overlap
PITX1 3 datasets
Motif DE_48h DE_48h-PITX1_MA0682.3 6 bp overlap
Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap
Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap
PITX3 3 datasets
Motif DE_48h DE_48h-PITX3_MA0714.2 6 bp overlap
Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap
Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap
Pparg::Rxra 1 dataset
Motif DE_60h DE_60h-PpargRxra_MA0065.3 13 bp overlap
RELA 2 datasets
Motif DE_48h DE_48h-RELA_MA0107.1 10 bp overlap
Motif DE_60h DE_60h-RELA_MA0107.1 10 bp overlap
REST 4 datasets
Motif DE_48h DE_48h-REST_MA0138.3 20 bp overlap
Motif DE_60h DE_60h-REST_MA0138.3 20 bp overlap
ChIP Hep-G2 ENCSR000BJL.REST.Hep-G2 89 bp overlap
ChIP HepG2 ENCFF122AWR 291 bp overlap
RHOXF1 3 datasets
Motif DE_48h DE_48h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 510 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 302 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 272 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 343 bp overlap
Sox11 3 datasets
Motif DE_48h DE_48h-Sox11_MA0869.3 8 bp overlap
Motif DE_60h DE_60h-Sox11_MA0869.3 8 bp overlap
Motif DE_72h DE_72h-Sox11_MA0869.3 8 bp overlap
TBX2 1 dataset
ChIP Kelly GSE94822.TBX2.Kelly 179 bp overlap
TRPS1 3 datasets
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
ZNF135 2 datasets
Motif DE_48h DE_48h-ZNF135_MA1587.1 14 bp overlap
Motif DE_72h DE_72h-ZNF135_MA1587.1 14 bp overlap
ZNF143 1 dataset
ChIP FLP76_T4 GSE39263.ZNF143.FLP76_T4 147 bp overlap
ZNF317 3 datasets
Motif DE_48h DE_48h-ZNF317_MA1593.2 8 bp overlap
Motif DE_60h DE_60h-ZNF317_MA1593.2 8 bp overlap
Motif DE_72h DE_72h-ZNF317_MA1593.2 8 bp overlap
ZNF382 3 datasets
Motif DE_48h DE_48h-ZNF382_MA1594.1 24 bp overlap
Motif DE_60h DE_60h-ZNF382_MA1594.1 24 bp overlap
Motif DE_72h DE_72h-ZNF382_MA1594.1 24 bp overlap
ZNF460 2 datasets
Motif DE_48h DE_48h-ZNF460_MA1596.1 16 bp overlap
Motif DE_72h DE_72h-ZNF460_MA1596.1 16 bp overlap
ZNF534 1 dataset
ChIP HEK293T GSE78099.ZNF534.HEK293T 88 bp overlap
ZNF677 3 datasets
Motif DE_48h DE_48h-ZNF677_MA2101.1 12 bp overlap
Motif DE_60h DE_60h-ZNF677_MA2101.1 12 bp overlap
Motif DE_72h DE_72h-ZNF677_MA2101.1 12 bp overlap
ZSCAN4 3 datasets
Motif DE_48h DE_48h-ZSCAN4_MA1155.1 15 bp overlap
Motif DE_60h DE_60h-ZSCAN4_MA1155.1 15 bp overlap
Motif DE_72h DE_72h-ZSCAN4_MA1155.1 15 bp overlap
Zfp809 3 datasets
Motif DE_48h DE_48h-Zfp809_MA2125.1 9 bp overlap
Motif DE_60h DE_60h-Zfp809_MA2125.1 9 bp overlap
Motif DE_72h DE_72h-Zfp809_MA2125.1 9 bp overlap
Zfx 2 datasets
Motif DE_48h DE_48h-Zfx_MA0146.3 10 bp overlap
Motif DE_72h DE_72h-Zfx_MA0146.3 10 bp overlap
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