chr8 : 119,717,408 – 119,717,936
528 bp 48 TFs 3 linked genes
This 528 bp open chromatin element is linked to ENPP2, TAF2, and DSCC1 and is bound by 48 transcription factors.
Linked Genes
3 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENPP2 44.1 kb Distal Multiome
TAF2 115.2 kb Distal Multiome
DSCC1 138.3 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr8:119,712,408 – 119,722,936
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
48 transcription factors
Source
Cell type
BRD4 1 dataset
ChIP Kelly_resistant GSE103030.BRD4.Kelly_resistant 121 bp overlap
E2F1 3 datasets
Motif DE_36h DE_36h-E2F1_MA0024.3 12 bp overlap
Motif DE_48h DE_48h-E2F1_MA0024.3 12 bp overlap
Motif DE_60h DE_60h-E2F1_MA0024.3 12 bp overlap
E2F2 3 datasets
Motif DE_36h DE_36h-E2F2_MA0864.3 13 bp overlap
Motif DE_48h DE_48h-E2F2_MA0864.3 13 bp overlap
Motif DE_60h DE_60h-E2F2_MA0864.3 13 bp overlap
E2F3 3 datasets
Motif DE_36h DE_36h-E2F3_MA0469.4 14 bp overlap
Motif DE_48h DE_48h-E2F3_MA0469.4 14 bp overlap
Motif DE_60h DE_60h-E2F3_MA0469.4 14 bp overlap
E2F4 3 datasets
Motif DE_36h DE_36h-E2F4_MA0470.3 13 bp overlap
Motif DE_48h DE_48h-E2F4_MA0470.3 13 bp overlap
Motif DE_60h DE_60h-E2F4_MA0470.3 13 bp overlap
EBF1 4 datasets
Motif DE_36h DE_36h-EBF1_MA0154.5 11 bp overlap
Motif DE_48h DE_48h-EBF1_MA0154.5 11 bp overlap
Motif DE_60h DE_60h-EBF1_MA0154.5 11 bp overlap
Motif DE_72h DE_72h-EBF1_MA0154.5 11 bp overlap
ESRRA 4 datasets
Motif DE_36h DE_36h-ESRRA_MA0592.4 9 bp overlap
Motif DE_48h DE_48h-ESRRA_MA0592.4 9 bp overlap
Motif DE_60h DE_60h-ESRRA_MA0592.4 9 bp overlap
Motif DE_72h DE_72h-ESRRA_MA0592.4 9 bp overlap
ESRRB 5 datasets
Motif DE_36h DE_36h-ESRRB_MA0141.4 10 bp overlap
Motif DE_48h DE_48h-ESRRB_MA0141.4 10 bp overlap
Motif DE_48h DE_48h-ESRRB_MA0141.4 10 bp overlap
Motif DE_60h DE_60h-ESRRB_MA0141.4 10 bp overlap
Motif DE_72h DE_72h-ESRRB_MA0141.4 10 bp overlap
Ebf4 4 datasets
Motif DE_36h DE_36h-Ebf4_MA2122.1 11 bp overlap
Motif DE_48h DE_48h-Ebf4_MA2122.1 11 bp overlap
Motif DE_60h DE_60h-Ebf4_MA2122.1 11 bp overlap
Motif DE_72h DE_72h-Ebf4_MA2122.1 11 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 365 bp overlap
ChIP DE DE-FOXA2-2 327 bp overlap
GATA1 3 datasets
ChIP CD34_ERYTH_BMP GSE29194.GATA1.CD34_ERYTH_BMP 82 bp overlap
ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 145 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 159 bp overlap
GATA4 7 datasets
ChIP DE DE-GATA4-1 440 bp overlap
ChIP DE DE-GATA4-2 528 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 351 bp overlap
GATA6 11 datasets
ChIP DE DE-GATA6-1 437 bp overlap
ChIP DE DE-GATA6-2 528 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 528 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 441 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 515 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 470 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 391 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 516 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 355 bp overlap
ChIP foregut GSE117136.GATA6.foregut 349 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 341 bp overlap
ISL2 3 datasets
Motif DE_36h DE_36h-ISL2_MA0914.2 6 bp overlap
Motif DE_48h DE_48h-ISL2_MA0914.2 6 bp overlap
Motif DE_60h DE_60h-ISL2_MA0914.2 6 bp overlap
Irf1 3 datasets
Motif DE_36h DE_36h-Irf1_MA0050.4 11 bp overlap
Motif DE_48h DE_48h-Irf1_MA0050.4 11 bp overlap
Motif DE_60h DE_60h-Irf1_MA0050.4 11 bp overlap
JUN 1 dataset
ChIP DE_D2 S02-DE-d2-JUN-exp1 269 bp overlap
LHX6 3 datasets
Motif DE_36h DE_36h-LHX6_MA0658.2 8 bp overlap
Motif DE_48h DE_48h-LHX6_MA0658.2 8 bp overlap
Motif DE_60h DE_60h-LHX6_MA0658.2 8 bp overlap
LIN54 4 datasets
Motif DE_36h DE_36h-LIN54_MA0619.2 7 bp overlap
Motif DE_48h DE_48h-LIN54_MA0619.2 7 bp overlap
Motif DE_60h DE_60h-LIN54_MA0619.2 7 bp overlap
Motif DE_72h DE_72h-LIN54_MA0619.2 7 bp overlap
Msgn1 3 datasets
Motif DE_36h DE_36h-Msgn1_MA1524.3 10 bp overlap
Motif DE_48h DE_48h-Msgn1_MA1524.3 10 bp overlap
Motif DE_60h DE_60h-Msgn1_MA1524.3 10 bp overlap
NANOG 1 dataset
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 379 bp overlap
NR2C1 1 dataset
Motif DE_48h DE_48h-NR2C1_MA1535.2 6 bp overlap
NR2C2 1 dataset
Motif DE_48h DE_48h-NR2C2_MA1536.2 6 bp overlap
NR5A1 5 datasets
Motif DE_36h DE_36h-NR5A1_MA1540.3 12 bp overlap
Motif DE_48h DE_48h-NR5A1_MA1540.3 12 bp overlap
Motif DE_48h DE_48h-NR5A1_MA1540.3 12 bp overlap
Motif DE_60h DE_60h-NR5A1_MA1540.3 12 bp overlap
Motif DE_72h DE_72h-NR5A1_MA1540.3 12 bp overlap
Nanog 4 datasets
Motif DE_36h DE_36h-Nanog_MA2339.1 7 bp overlap
Motif DE_48h DE_48h-Nanog_MA2339.1 7 bp overlap
Motif DE_60h DE_60h-Nanog_MA2339.1 7 bp overlap
Motif DE_72h DE_72h-Nanog_MA2339.1 7 bp overlap
Nkx3-1 3 datasets
Motif DE_36h DE_36h-Nkx3-1_MA0124.3 7 bp overlap
Motif DE_48h DE_48h-Nkx3-1_MA0124.3 7 bp overlap
Motif DE_60h DE_60h-Nkx3-1_MA0124.3 7 bp overlap
Nr1H2 1 dataset
Motif DE_48h DE_48h-Nr1H2_MA1996.2 6 bp overlap
Nr1H4 1 dataset
Motif DE_48h DE_48h-Nr1H4_MA1110.3 6 bp overlap
Nr1h3 1 dataset
Motif DE_48h DE_48h-Nr1h3_MA2337.1 6 bp overlap
Nr5A2 4 datasets
Motif DE_36h DE_36h-Nr5A2_MA0505.3 9 bp overlap
Motif DE_48h DE_48h-Nr5A2_MA0505.3 9 bp overlap
Motif DE_60h DE_60h-Nr5A2_MA0505.3 9 bp overlap
Motif DE_72h DE_72h-Nr5A2_MA0505.3 9 bp overlap
POU5F1 1 dataset
ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 255 bp overlap
Prdm5 3 datasets
Motif DE_36h DE_36h-Prdm5_MA1999.2 11 bp overlap
Motif DE_48h DE_48h-Prdm5_MA1999.2 11 bp overlap
Motif DE_60h DE_60h-Prdm5_MA1999.2 11 bp overlap
RBPJ 7 datasets
Motif DE_36h DE_36h-RBPJ_MA1116.2 6 bp overlap
Motif DE_36h DE_36h-RBPJ_MA1116.2 6 bp overlap
Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap
Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap
Motif DE_60h DE_60h-RBPJ_MA1116.2 6 bp overlap
Motif DE_60h DE_60h-RBPJ_MA1116.2 6 bp overlap
Motif DE_72h DE_72h-RBPJ_MA1116.2 6 bp overlap
RORA 1 dataset
Motif DE_48h DE_48h-RORA_MA0071.1 10 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 284 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 326 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 431 bp overlap
SMAD2_3 4 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 431 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 528 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 463 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 271 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 380 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 471 bp overlap
SP5 4 datasets
Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap
Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap
THRB 2 datasets
Motif DE_48h DE_48h-THRB_MA1574.2 13 bp overlap
Motif DE_48h DE_48h-THRB_MA1576.2 18 bp overlap
ZIM3 3 datasets
Motif DE_36h DE_36h-ZIM3_MA1709.2 11 bp overlap
Motif DE_48h DE_48h-ZIM3_MA1709.2 11 bp overlap
Motif DE_60h DE_60h-ZIM3_MA1709.2 11 bp overlap
ZNF184 1 dataset
Motif DE_48h DE_48h-ZNF184_MA2120.1 13 bp overlap
ZNF274 3 datasets
Motif DE_36h DE_36h-ZNF274_MA1592.2 12 bp overlap
Motif DE_48h DE_48h-ZNF274_MA1592.2 12 bp overlap
Motif DE_60h DE_60h-ZNF274_MA1592.2 12 bp overlap
ZNF354A 3 datasets
Motif DE_36h DE_36h-ZNF354A_MA1978.2 20 bp overlap
Motif DE_48h DE_48h-ZNF354A_MA1978.2 20 bp overlap
Motif DE_60h DE_60h-ZNF354A_MA1978.2 20 bp overlap
ZNF417 3 datasets
Motif DE_36h DE_36h-ZNF417_MA1727.2 7 bp overlap
Motif DE_48h DE_48h-ZNF417_MA1727.2 7 bp overlap
Motif DE_60h DE_60h-ZNF417_MA1727.2 7 bp overlap
ZNF75A 2 datasets
Motif DE_48h DE_48h-ZNF75A_MA2097.1 12 bp overlap
Motif DE_60h DE_60h-ZNF75A_MA2097.1 12 bp overlap
ZNF768 4 datasets
Motif DE_36h DE_36h-ZNF768_MA1731.2 9 bp overlap
Motif DE_48h DE_48h-ZNF768_MA1731.2 9 bp overlap
Motif DE_60h DE_60h-ZNF768_MA1731.2 9 bp overlap
Motif DE_72h DE_72h-ZNF768_MA1731.2 9 bp overlap
Zfp809 4 datasets
Motif DE_36h DE_36h-Zfp809_MA2125.1 9 bp overlap
Motif DE_48h DE_48h-Zfp809_MA2125.1 9 bp overlap
Motif DE_60h DE_60h-Zfp809_MA2125.1 9 bp overlap
Motif DE_72h DE_72h-Zfp809_MA2125.1 9 bp overlap
Zfp961 3 datasets
Motif DE_36h DE_36h-Zfp961_MA2126.1 8 bp overlap
Motif DE_48h DE_48h-Zfp961_MA2126.1 8 bp overlap
Motif DE_60h DE_60h-Zfp961_MA2126.1 8 bp overlap
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