chr8 : 132,589,830 – 132,590,792
962 bp 70 TFs 3 linked genes
This 962 bp open chromatin element is linked to DNAAF11, KCNQ3, and PHF20L1 and is bound by 70 transcription factors.
Linked Genes
3 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
DNAAF11 35.1 kb Distal Multiome
KCNQ3 109.2 kb Distal Multiome
PHF20L1 185.1 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr8:132,584,830 – 132,595,792
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
70 transcription factors
Source
Cell type
AR 1 dataset
ChIP MDA-MB-453_FOXA1 ERP003503.AR.MDA-MB-453_FOXA1 145 bp overlap
ARNT::HIF1A 3 datasets
Motif DE_48h DE_48h-ARNTHIF1A_MA0259.2 5 bp overlap
Motif DE_60h DE_60h-ARNTHIF1A_MA0259.2 5 bp overlap
Motif DE_72h DE_72h-ARNTHIF1A_MA0259.2 5 bp overlap
ARNTL 1 dataset
ChIP U2OS GSE44236.ARNTL.U2OS 338 bp overlap
BRD4 1 dataset
ChIP IMR-90_QUIES GSE74238.BRD4.IMR-90_QUIES 172 bp overlap
CEBPA 3 datasets
Motif DE_48h DE_48h-CEBPA_MA0102.5 10 bp overlap
Motif DE_60h DE_60h-CEBPA_MA0102.5 10 bp overlap
Motif DE_72h DE_72h-CEBPA_MA0102.5 10 bp overlap
CEBPD 3 datasets
Motif DE_48h DE_48h-CEBPD_MA0836.3 8 bp overlap
Motif DE_60h DE_60h-CEBPD_MA0836.3 8 bp overlap
Motif DE_72h DE_72h-CEBPD_MA0836.3 8 bp overlap
CHD8 1 dataset
ChIP T-47D_ETOH_45 GSE62428.CHD8.T-47D_ETOH_45 273 bp overlap
E2F6 3 datasets
Motif DE_48h DE_48h-E2F6_MA0471.3 8 bp overlap
Motif DE_60h DE_60h-E2F6_MA0471.3 8 bp overlap
Motif DE_72h DE_72h-E2F6_MA0471.3 8 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 189 bp overlap
EPAS1 3 datasets
Motif DE_48h DE_48h-EPAS1_MA2325.1 9 bp overlap
Motif DE_60h DE_60h-EPAS1_MA2325.1 9 bp overlap
Motif DE_72h DE_72h-EPAS1_MA2325.1 9 bp overlap
ERF::FOXI1 3 datasets
Motif DE_36h DE_36h-ERFFOXI1_MA1935.2 10 bp overlap
Motif DE_48h DE_48h-ERFFOXI1_MA1935.2 10 bp overlap
Motif DE_60h DE_60h-ERFFOXI1_MA1935.2 10 bp overlap
ERG 1 dataset
ChIP HUVEC-C GSE124891.ERG.HUVEC-C 149 bp overlap
ESR1 3 datasets
ChIP MCF-7_IL1b_IKK7 GSE67295.ESR1.MCF-7_IL1b_IKK7 196 bp overlap
ChIP MCF-7_Veh GSE93510.ESR1.MCF-7_Veh 304 bp overlap
ChIP breast_tumor_BADOUTCOME GSE40867.ESR1.breast_tumor_BADOUTCOME 203 bp overlap
ESR1_Y537S 1 dataset
ChIP MCF-7_dox GSE94493.ESR1_Y537S.MCF-7_dox 174 bp overlap
ETV1 3 datasets
Motif DE_36h DE_36h-ETV1_MA0761.3 9 bp overlap
Motif DE_48h DE_48h-ETV1_MA0761.3 9 bp overlap
Motif DE_60h DE_60h-ETV1_MA0761.3 9 bp overlap
EWSR1-FLI1 3 datasets
Motif DE_48h DE_48h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_60h DE_60h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_72h DE_72h-EWSR1-FLI1_MA0149.1 18 bp overlap
Erg 3 datasets
Motif DE_36h DE_36h-Erg_MA0474.4 10 bp overlap
Motif DE_48h DE_48h-Erg_MA0474.4 10 bp overlap
Motif DE_60h DE_60h-Erg_MA0474.4 10 bp overlap
FIGLA 4 datasets
Motif DE_36h DE_36h-FIGLA_MA0820.2 6 bp overlap
Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap
Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap
Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 894 bp overlap
ChIP DE DE-FOXA2-2 835 bp overlap
FOXJ2::ELF1 3 datasets
Motif DE_36h DE_36h-FOXJ2ELF1_MA1952.2 11 bp overlap
Motif DE_48h DE_48h-FOXJ2ELF1_MA1952.2 11 bp overlap
Motif DE_60h DE_60h-FOXJ2ELF1_MA1952.2 11 bp overlap
FOXO1::ELF1 3 datasets
Motif DE_36h DE_36h-FOXO1ELF1_MA1953.2 13 bp overlap
Motif DE_48h DE_48h-FOXO1ELF1_MA1953.2 13 bp overlap
Motif DE_60h DE_60h-FOXO1ELF1_MA1953.2 13 bp overlap
FOXO1::ELK1 3 datasets
Motif DE_36h DE_36h-FOXO1ELK1_MA1954.2 13 bp overlap
Motif DE_48h DE_48h-FOXO1ELK1_MA1954.2 13 bp overlap
Motif DE_60h DE_60h-FOXO1ELK1_MA1954.2 13 bp overlap
GABPA 3 datasets
Motif DE_36h DE_36h-GABPA_MA0062.4 10 bp overlap
Motif DE_48h DE_48h-GABPA_MA0062.4 10 bp overlap
Motif DE_60h DE_60h-GABPA_MA0062.4 10 bp overlap
GATA4 3 datasets
ChIP DE DE-GATA4-1 413 bp overlap
ChIP DE DE-GATA4-1 338 bp overlap
ChIP DE DE-GATA4-2 905 bp overlap
GATA6 6 datasets
ChIP DE DE-GATA6-1 901 bp overlap
ChIP DE DE-GATA6-2 872 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 872 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 269 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 475 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 285 bp overlap
GFI1 3 datasets
Motif DE_36h DE_36h-GFI1_MA0038.3 11 bp overlap
Motif DE_48h DE_48h-GFI1_MA0038.3 11 bp overlap
Motif DE_60h DE_60h-GFI1_MA0038.3 11 bp overlap
GRHL1 2 datasets
Motif DE_36h DE_36h-GRHL1_MA0647.2 10 bp overlap
Motif DE_48h DE_48h-GRHL1_MA0647.2 10 bp overlap
GRHL2 2 datasets
Motif DE_36h DE_36h-GRHL2_MA1105.3 8 bp overlap
Motif DE_48h DE_48h-GRHL2_MA1105.3 8 bp overlap
Gfi1B 3 datasets
Motif DE_36h DE_36h-Gfi1B_MA0483.2 10 bp overlap
Motif DE_48h DE_48h-Gfi1B_MA0483.2 10 bp overlap
Motif DE_60h DE_60h-Gfi1B_MA0483.2 10 bp overlap
HIF1A 4 datasets
Motif DE_48h DE_48h-HIF1A_MA1106.2 6 bp overlap
Motif DE_60h DE_60h-HIF1A_MA1106.2 6 bp overlap
Motif DE_72h DE_72h-HIF1A_MA1106.2 6 bp overlap
ChIP U2OS_trough_DMOG GSE85096.HIF1A.U2OS_trough_DMOG 259 bp overlap
IKZF1 3 datasets
Motif DE_36h DE_36h-IKZF1_MA1508.2 8 bp overlap
Motif DE_48h DE_48h-IKZF1_MA1508.2 8 bp overlap
Motif DE_60h DE_60h-IKZF1_MA1508.2 8 bp overlap
IKZF2 3 datasets
Motif DE_36h DE_36h-IKZF2_MA2326.1 6 bp overlap
Motif DE_48h DE_48h-IKZF2_MA2326.1 6 bp overlap
Motif DE_60h DE_60h-IKZF2_MA2326.1 6 bp overlap
IRF2 3 datasets
Motif DE_36h DE_36h-IRF2_MA0051.2 16 bp overlap
Motif DE_48h DE_48h-IRF2_MA0051.2 16 bp overlap
Motif DE_60h DE_60h-IRF2_MA0051.2 16 bp overlap
Ikzf3 3 datasets
Motif DE_36h DE_36h-Ikzf3_MA1992.2 9 bp overlap
Motif DE_48h DE_48h-Ikzf3_MA1992.2 9 bp overlap
Motif DE_60h DE_60h-Ikzf3_MA1992.2 9 bp overlap
MAFF 3 datasets
Motif DE_48h DE_48h-MAFF_MA0495.4 11 bp overlap
Motif DE_60h DE_60h-MAFF_MA0495.4 11 bp overlap
Motif DE_72h DE_72h-MAFF_MA0495.4 11 bp overlap
MYOD1 3 datasets
Motif DE_36h DE_36h-MYOD1_MA0499.3 9 bp overlap
Motif DE_48h DE_48h-MYOD1_MA0499.3 9 bp overlap
ChIP RD_shSNAI2 GSE137168.MYOD1.RD_shSNAI2 334 bp overlap
Mafb 3 datasets
Motif DE_48h DE_48h-Mafb_MA0117.3 11 bp overlap
Motif DE_60h DE_60h-Mafb_MA0117.3 11 bp overlap
Motif DE_72h DE_72h-Mafb_MA0117.3 11 bp overlap
NFYB 3 datasets
Motif DE_48h DE_48h-NFYB_MA0502.3 9 bp overlap
Motif DE_60h DE_60h-NFYB_MA0502.3 9 bp overlap
Motif DE_72h DE_72h-NFYB_MA0502.3 9 bp overlap
NR3C1 1 dataset
ChIP A-549 ENCSR000BHE.NR3C1.A-549 145 bp overlap
NRL 3 datasets
Motif DE_48h DE_48h-NRL_MA0842.3 12 bp overlap
Motif DE_60h DE_60h-NRL_MA0842.3 12 bp overlap
Motif DE_72h DE_72h-NRL_MA0842.3 12 bp overlap
PKNOX1 3 datasets
Motif DE_36h DE_36h-PKNOX1_MA0782.3 10 bp overlap
Motif DE_48h DE_48h-PKNOX1_MA0782.3 10 bp overlap
Motif DE_60h DE_60h-PKNOX1_MA0782.3 10 bp overlap
POU2F2 1 dataset
ChIP HNPC_UNDIF GSE74814.POU2F2.HNPC_UNDIF 119 bp overlap
Pgr 3 datasets
Motif DE_48h DE_48h-Pgr_MA2323.1 17 bp overlap
Motif DE_60h DE_60h-Pgr_MA2323.1 17 bp overlap
Motif DE_72h DE_72h-Pgr_MA2323.1 17 bp overlap
Prdm5 3 datasets
Motif DE_48h DE_48h-Prdm5_MA1999.2 11 bp overlap
Motif DE_60h DE_60h-Prdm5_MA1999.2 11 bp overlap
Motif DE_72h DE_72h-Prdm5_MA1999.2 11 bp overlap
Ptf1A 2 datasets
Motif DE_36h DE_36h-Ptf1A_MA1620.2 8 bp overlap
Motif DE_48h DE_48h-Ptf1A_MA1620.2 8 bp overlap
RBPJ 1 dataset
Motif DE_60h DE_60h-RBPJ_MA1116.2 6 bp overlap
Rarg 3 datasets
Motif DE_36h DE_36h-Rarg_MA0860.1 17 bp overlap
Motif DE_48h DE_48h-Rarg_MA0860.1 17 bp overlap
Motif DE_48h DE_48h-Rarg_MA0860.1 17 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 318 bp overlap
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 298 bp overlap
SMAD2_3 1 dataset
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 227 bp overlap
SNAI2 3 datasets
Motif DE_36h DE_36h-SNAI2_MA0745.3 8 bp overlap
Motif DE_48h DE_48h-SNAI2_MA0745.3 8 bp overlap
ChIP SMS-CTR_T48 GSE137168.SNAI2.SMS-CTR_T48 278 bp overlap
SNAI3 2 datasets
Motif DE_36h DE_36h-SNAI3_MA1559.2 9 bp overlap
Motif DE_48h DE_48h-SNAI3_MA1559.2 9 bp overlap
SOX21 3 datasets
Motif DE_48h DE_48h-SOX21_MA0866.1 15 bp overlap
Motif DE_60h DE_60h-SOX21_MA0866.1 15 bp overlap
Motif DE_72h DE_72h-SOX21_MA0866.1 15 bp overlap
SP5 3 datasets
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap
Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 179 bp overlap
TCF4 2 datasets
Motif DE_36h DE_36h-TCF4_MA0830.3 8 bp overlap
Motif DE_48h DE_48h-TCF4_MA0830.3 8 bp overlap
TFAP2C 1 dataset
ChIP HCC1954 GSE126897.TFAP2C.HCC1954 153 bp overlap
ZBTB7A 1 dataset
ChIP VCaP_FBS GSE123089.ZBTB7A.VCaP_FBS 389 bp overlap
ZEB1 4 datasets
Motif DE_36h DE_36h-ZEB1_MA0103.4 6 bp overlap
Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap
Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap
Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap
ZFP14 6 datasets
Motif DE_48h DE_48h-ZFP14_MA1972.1 15 bp overlap
Motif DE_48h DE_48h-ZFP14_MA1972.1 15 bp overlap
Motif DE_60h DE_60h-ZFP14_MA1972.1 15 bp overlap
Motif DE_60h DE_60h-ZFP14_MA1972.1 15 bp overlap
Motif DE_72h DE_72h-ZFP14_MA1972.1 15 bp overlap
Motif DE_72h DE_72h-ZFP14_MA1972.1 15 bp overlap
ZNF16 3 datasets
Motif DE_48h DE_48h-ZNF16_MA1654.2 21 bp overlap
Motif DE_60h DE_60h-ZNF16_MA1654.2 21 bp overlap
Motif DE_72h DE_72h-ZNF16_MA1654.2 21 bp overlap
ZNF175 3 datasets
Motif DE_36h DE_36h-ZNF175_MA2332.1 9 bp overlap
Motif DE_48h DE_48h-ZNF175_MA2332.1 9 bp overlap
Motif DE_60h DE_60h-ZNF175_MA2332.1 9 bp overlap
ZNF331 3 datasets
Motif DE_36h DE_36h-ZNF331_MA1726.2 10 bp overlap
Motif DE_48h DE_48h-ZNF331_MA1726.2 10 bp overlap
Motif DE_60h DE_60h-ZNF331_MA1726.2 10 bp overlap
ZNF354C 3 datasets
Motif DE_36h DE_36h-ZNF354C_MA0130.1 6 bp overlap
Motif DE_48h DE_48h-ZNF354C_MA0130.1 6 bp overlap
Motif DE_60h DE_60h-ZNF354C_MA0130.1 6 bp overlap
ZNF454 3 datasets
Motif DE_48h DE_48h-ZNF454_MA1712.2 17 bp overlap
Motif DE_60h DE_60h-ZNF454_MA1712.2 17 bp overlap
Motif DE_72h DE_72h-ZNF454_MA1712.2 17 bp overlap
ZNF75D 3 datasets
Motif DE_48h DE_48h-ZNF75D_MA1601.2 12 bp overlap
Motif DE_60h DE_60h-ZNF75D_MA1601.2 12 bp overlap
Motif DE_72h DE_72h-ZNF75D_MA1601.2 12 bp overlap
Zfp335 2 datasets
Motif DE_36h DE_36h-Zfp335_MA2002.2 7 bp overlap
Motif DE_48h DE_48h-Zfp335_MA2002.2 7 bp overlap
Zfp809 1 dataset
Motif DE_60h DE_60h-Zfp809_MA2125.1 9 bp overlap
Zfx 3 datasets
Motif DE_48h DE_48h-Zfx_MA0146.3 10 bp overlap
Motif DE_60h DE_60h-Zfx_MA0146.3 10 bp overlap
Motif DE_72h DE_72h-Zfx_MA0146.3 10 bp overlap
Zic1::Zic2 4 datasets
Motif DE_36h DE_36h-Zic1Zic2_MA1628.2 7 bp overlap
Motif DE_48h DE_48h-Zic1Zic2_MA1628.2 7 bp overlap
Motif DE_48h DE_48h-Zic1Zic2_MA1628.2 7 bp overlap
Motif DE_60h DE_60h-Zic1Zic2_MA1628.2 7 bp overlap
Zic3 4 datasets
Motif DE_36h DE_36h-Zic3_MA0697.3 7 bp overlap
Motif DE_48h DE_48h-Zic3_MA0697.3 7 bp overlap
Motif DE_48h DE_48h-Zic3_MA0697.3 7 bp overlap
Motif DE_60h DE_60h-Zic3_MA0697.3 7 bp overlap
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