chr9 : 100,664,438 – 100,664,921

483 bp 46 TFs 3 linked genes

This 483 bp open chromatin element is linked to CAVIN4, TMEFF1, and MSANTD3 and is bound by 46 transcription factors.

Linked Genes

3 genes

Gene	Dist. to TSS	Distance	Link type
CAVIN4	86.7 kb	Distal	Multiome
TMEFF1	191.6 kb	Distal	Multiome
MSANTD3	237.3 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

46 transcription factors

CTCF 1 dataset

Motif DE_60h DE_60h-CTCF_MA1929.2 31 bp overlap

DMRTA2 4 datasets

Motif DE_48h DE_48h-DMRTA2_MA1478.2 6 bp overlap

Motif DE_60h DE_60h-DMRTA2_MA1478.2 6 bp overlap

Motif DE_72h DE_72h-DMRTA2_MA1478.2 6 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 153 bp overlap

ESR1 2 datasets

ChIP Ishikawa ENCSR000BQR.ESR1.Ishikawa 109 bp overlap

ChIP MCF-7_Veh GSE67295.ESR1.MCF-7_Veh 159 bp overlap

EZH2 2 datasets

ChIP LNCaP GSE39459.EZH2.LNCaP 379 bp overlap

ChIP SU-DHL-5 GSE45982.EZH2.SU-DHL-5 164 bp overlap

FEZF2 1 dataset

Motif DE_60h DE_60h-FEZF2_MA2341.1 8 bp overlap

FOSL1 1 dataset

ChIP K-562 ENCSR000BMV.FOSL1.K-562 126 bp overlap

GATA1 1 dataset

Motif DE_60h DE_60h-GATA1_MA0035.5 7 bp overlap

GATA1::TAL1 2 datasets

Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap

Motif DE_60h DE_60h-GATA1TAL1_MA0140.3 17 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 483 bp overlap

ChIP DE DE-GATA4-2 483 bp overlap

ChIP foregut GSE117136.GATA4.foregut 216 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 483 bp overlap

ChIP DE DE-GATA6-2 483 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 317 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 435 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 288 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 433 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 483 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 352 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 366 bp overlap

HNF1A 2 datasets

Motif DE_60h DE_60h-HNF1A_MA0046.3 13 bp overlap

Motif DE_72h DE_72h-HNF1A_MA0046.3 13 bp overlap

HNRNPK 1 dataset

ChIP Hep-G2 GSE120104.HNRNPK.Hep-G2 60 bp overlap

HOXB4 1 dataset

Motif DE_60h DE_60h-HOXB4_MA1499.2 6 bp overlap

HOXC4 1 dataset

Motif DE_60h DE_60h-HOXC4_MA1504.2 6 bp overlap

HOXD3 1 dataset

Motif DE_60h DE_60h-HOXD3_MA0912.2 8 bp overlap

HOXD4 1 dataset

Motif DE_60h DE_60h-HOXD4_MA1507.2 6 bp overlap

Hand1 1 dataset

Motif DE_60h DE_60h-Hand1_MA2123.1 9 bp overlap

KLF4 1 dataset

Motif DE_60h DE_60h-KLF4_MA0039.5 8 bp overlap

MBD3 1 dataset

ChIP HEK293T GSE102945.MBD3.HEK293T 238 bp overlap

MED26 1 dataset

ChIP HEK293T GSE121024.MED26.HEK293T 227 bp overlap

MYNN 1 dataset

ChIP K-562 ENCSR737LTZ.MYNN.K-562 118 bp overlap

Mafg 1 dataset

Motif DE_60h DE_60h-Mafg_MA0659.4 12 bp overlap

NCOA2 1 dataset

ChIP MCF-7 ERP000901.NCOA2.MCF-7 134 bp overlap

POU5F1 1 dataset

ChIP SKM-1 GSE93706.POU5F1.SKM-1 182 bp overlap

POU6F1 1 dataset

Motif DE_60h DE_60h-POU6F1_MA1549.2 7 bp overlap

PPARG 1 dataset

ChIP HUVEC-C_PPARG_HYPO GSE50144.PPARG.HUVEC-C_PPARG_HYPO 123 bp overlap

SMAD2 1 dataset

Motif DE_60h DE_60h-SMAD2_MA1964.2 6 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 483 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 406 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 262 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 443 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 345 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 366 bp overlap

Stat6 1 dataset

Motif DE_60h DE_60h-Stat6_MA0520.2 10 bp overlap

THRA 1 dataset

Motif DE_60h DE_60h-THRA_MA1969.2 18 bp overlap

ZIC1 1 dataset

Motif DE_60h DE_60h-ZIC1_MA0696.1 14 bp overlap

ZIC4 1 dataset

Motif DE_60h DE_60h-ZIC4_MA0751.2 14 bp overlap

ZIC5 1 dataset

Motif DE_60h DE_60h-ZIC5_MA1584.2 15 bp overlap

ZNF281 1 dataset

Motif DE_60h DE_60h-ZNF281_MA1630.3 10 bp overlap

ZNF320 2 datasets

Motif DE_60h DE_60h-ZNF320_MA1976.2 20 bp overlap

Motif DE_72h DE_72h-ZNF320_MA1976.2 20 bp overlap

ZNF324 2 datasets

Motif DE_48h DE_48h-ZNF324_MA1977.2 14 bp overlap

Motif DE_60h DE_60h-ZNF324_MA1977.2 14 bp overlap

ZNF331 1 dataset

Motif DE_60h DE_60h-ZNF331_MA1726.2 10 bp overlap

ZNF449 1 dataset

Motif DE_60h DE_60h-ZNF449_MA1656.2 10 bp overlap

ZNF460 1 dataset

Motif DE_60h DE_60h-ZNF460_MA1596.1 16 bp overlap

ZNF582 2 datasets

Motif DE_48h DE_48h-ZNF582_MA1983.2 19 bp overlap

Motif DE_60h DE_60h-ZNF582_MA1983.2 19 bp overlap

ZNF684 1 dataset

Motif DE_60h DE_60h-ZNF684_MA1600.2 14 bp overlap

ZNF736 1 dataset

ChIP HEK293T GSE78099.ZNF736.HEK293T 141 bp overlap

ZNF770 1 dataset

Motif DE_60h DE_60h-ZNF770_MA2099.1 8 bp overlap