chr10 : 7,466,885 – 7,467,532
647 bp 76 TFs 2 linked genes
This 647 bp open chromatin element is linked to SFMBT2 and ITIH5 and is bound by 76 transcription factors.
Linked Genes
2 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
SFMBT2 55.8 kb Distal Multiome
ITIH5 199.7 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr10:7,461,885 – 7,472,532
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
76 transcription factors
Source
Cell type
Atoh1 1 dataset
Motif DE_60h DE_60h-Atoh1_MA1467.3 7 bp overlap
BCL6 1 dataset
Motif DE_48h DE_48h-BCL6_MA0463.3 13 bp overlap
BRD4 1 dataset
ChIP CHL-1 GSE95585.BRD4.CHL-1 312 bp overlap
CHD8 1 dataset
ChIP T-47D_ETOH_45 GSE62428.CHD8.T-47D_ETOH_45 155 bp overlap
DDX5 1 dataset
ChIP BT-549 GSE112961.DDX5.BT-549 196 bp overlap
EGR4 2 datasets
Motif DE_36h DE_36h-EGR4_MA0733.2 11 bp overlap
Motif DE_60h DE_60h-EGR4_MA0733.2 11 bp overlap
EHF 1 dataset
Motif DE_48h DE_48h-EHF_MA0598.4 9 bp overlap
ELF1 4 datasets
ChIP A-549 GSE122203.ELF1.A-549 121 bp overlap
ChIP Hep-G2 ENCSR000BMZ.ELF1.Hep-G2 142 bp overlap
ChIP K-562 ENCSR000BMD.ELF1.K-562 435 bp overlap
ChIP K562 ENCFF496AKI 83 bp overlap
ELF2 3 datasets
Motif DE_36h DE_36h-ELF2_MA1483.3 10 bp overlap
Motif DE_48h DE_48h-ELF2_MA1483.3 10 bp overlap
Motif DE_60h DE_60h-ELF2_MA1483.3 10 bp overlap
ELF3 4 datasets
Motif DE_48h DE_48h-ELF3_MA0640.3 9 bp overlap
ChIP PDAC GSE64557.ELF3.PDAC 448 bp overlap
ChIP PDAC_KOKLF5 GSE64557.ELF3.PDAC_KOKLF5 559 bp overlap
ChIP PDAC_SHCTR GSE64557.ELF3.PDAC_SHCTR 437 bp overlap
ELF4 3 datasets
Motif DE_36h DE_36h-ELF4_MA0641.1 12 bp overlap
Motif DE_60h DE_60h-ELF4_MA0641.1 12 bp overlap
ChIP K-562 ENCSR638QHV.ELF4.K-562 302 bp overlap
ELK1::SREBF2 2 datasets
Motif DE_36h DE_36h-ELK1SREBF2_MA1933.2 15 bp overlap
Motif DE_60h DE_60h-ELK1SREBF2_MA1933.2 15 bp overlap
ELK4 2 datasets
Motif DE_36h DE_36h-ELK4_MA0076.3 9 bp overlap
Motif DE_60h DE_60h-ELK4_MA0076.3 9 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 271 bp overlap
ETV1 1 dataset
Motif DE_48h DE_48h-ETV1_MA0761.3 9 bp overlap
ETV6 2 datasets
Motif DE_36h DE_36h-ETV6_MA0645.2 9 bp overlap
Motif DE_60h DE_60h-ETV6_MA0645.2 9 bp overlap
ETV7 2 datasets
Motif DE_36h DE_36h-ETV7_MA1708.2 9 bp overlap
Motif DE_60h DE_60h-ETV7_MA1708.2 9 bp overlap
Elf5 1 dataset
Motif DE_60h DE_60h-Elf5_MA0136.4 8 bp overlap
FEV 2 datasets
Motif DE_36h DE_36h-FEV_MA0156.4 9 bp overlap
Motif DE_60h DE_60h-FEV_MA0156.4 9 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 545 bp overlap
ChIP DE DE-FOXA2-2 537 bp overlap
FOXJ2::ELF1 3 datasets
Motif DE_36h DE_36h-FOXJ2ELF1_MA1952.2 11 bp overlap
Motif DE_48h DE_48h-FOXJ2ELF1_MA1952.2 11 bp overlap
Motif DE_60h DE_60h-FOXJ2ELF1_MA1952.2 11 bp overlap
FOXS1 1 dataset
Motif DE_60h DE_60h-FOXS1_MA2118.1 8 bp overlap
GATA4 2 datasets
ChIP DE DE-GATA4-1 448 bp overlap
ChIP DE DE-GATA4-2 516 bp overlap
GATA6 3 datasets
ChIP DE DE-GATA6-1 426 bp overlap
ChIP DE DE-GATA6-2 495 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 261 bp overlap
GLI3 2 datasets
Motif DE_36h DE_36h-GLI3_MA1491.3 15 bp overlap
Motif DE_60h DE_60h-GLI3_MA1491.3 15 bp overlap
Gli1 2 datasets
Motif DE_36h DE_36h-Gli1_MA1990.2 10 bp overlap
Motif DE_60h DE_60h-Gli1_MA1990.2 10 bp overlap
Gli2 2 datasets
Motif DE_36h DE_36h-Gli2_MA0734.4 9 bp overlap
Motif DE_60h DE_60h-Gli2_MA0734.4 9 bp overlap
HAND2 3 datasets
Motif DE_36h DE_36h-HAND2_MA1638.2 6 bp overlap
Motif DE_60h DE_60h-HAND2_MA1638.2 6 bp overlap
Motif DE_60h DE_60h-HAND2_MA1638.2 6 bp overlap
HNF1A 2 datasets
Motif DE_36h DE_36h-HNF1A_MA0046.3 13 bp overlap
Motif DE_60h DE_60h-HNF1A_MA0046.3 13 bp overlap
HNF1B 2 datasets
Motif DE_36h DE_36h-HNF1B_MA0153.2 13 bp overlap
Motif DE_60h DE_60h-HNF1B_MA0153.2 13 bp overlap
IKZF2 1 dataset
Motif DE_60h DE_60h-IKZF2_MA2326.1 6 bp overlap
KDM4C 1 dataset
ChIP KYSE-150 GSE53938.KDM4C.KYSE-150 173 bp overlap
Lef1 2 datasets
Motif DE_48h DE_48h-Lef1_MA0768.3 8 bp overlap
Motif DE_60h DE_60h-Lef1_MA0768.3 8 bp overlap
MEIS1 2 datasets
Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
MTF2 1 dataset
ChIP DU145_SH4 GSE135623.MTF2.DU145_SH4 262 bp overlap
NEUROD1 3 datasets
Motif DE_36h DE_36h-NEUROD1_MA1109.2 8 bp overlap
Motif DE_60h DE_60h-NEUROD1_MA1109.2 8 bp overlap
Motif DE_60h DE_60h-NEUROD1_MA1109.2 8 bp overlap
NEUROG2 3 datasets
Motif DE_36h DE_36h-NEUROG2_MA1642.2 7 bp overlap
Motif DE_60h DE_60h-NEUROG2_MA1642.2 7 bp overlap
Motif DE_60h DE_60h-NEUROG2_MA1642.2 7 bp overlap
Neurod2 3 datasets
Motif DE_36h DE_36h-Neurod2_MA0668.3 8 bp overlap
Motif DE_60h DE_60h-Neurod2_MA0668.3 8 bp overlap
Motif DE_60h DE_60h-Neurod2_MA0668.3 8 bp overlap
PDX1 1 dataset
ChIP hiPSC GSE125768.PDX1.hiPSC 185 bp overlap
PHOX2A 2 datasets
Motif DE_36h DE_36h-PHOX2A_MA0713.1 11 bp overlap
Motif DE_60h DE_60h-PHOX2A_MA0713.1 11 bp overlap
PKNOX2 2 datasets
Motif DE_36h DE_36h-PKNOX2_MA0783.1 12 bp overlap
Motif DE_60h DE_60h-PKNOX2_MA0783.1 12 bp overlap
POU1F1 2 datasets
Motif DE_48h DE_48h-POU1F1_MA0784.3 14 bp overlap
Motif DE_60h DE_60h-POU1F1_MA0784.3 14 bp overlap
POU2F2 2 datasets
Motif DE_48h DE_48h-POU2F2_MA0507.3 13 bp overlap
Motif DE_60h DE_60h-POU2F2_MA0507.3 13 bp overlap
POU3F2 2 datasets
Motif DE_48h DE_48h-POU3F2_MA0787.1 12 bp overlap
Motif DE_60h DE_60h-POU3F2_MA0787.1 12 bp overlap
POU5F1 1 dataset
ChIP DE_D1 DED1-OCT4_Batch_II 287 bp overlap
Ptf1A 2 datasets
Motif DE_36h DE_36h-Ptf1A_MA1618.2 9 bp overlap
Motif DE_60h DE_60h-Ptf1A_MA1618.2 9 bp overlap
RBPJ 1 dataset
Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 297 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 590 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 376 bp overlap
SMAD2_3 4 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 307 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 281 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 539 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 450 bp overlap
SMAD3 1 dataset
ChIP endoderm GSE29422.SMAD3.endoderm 218 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 312 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 494 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 540 bp overlap
SP5 2 datasets
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap
SPDEF 2 datasets
Motif DE_36h DE_36h-SPDEF_MA0686.2 10 bp overlap
Motif DE_60h DE_60h-SPDEF_MA0686.2 10 bp overlap
Smad4 1 dataset
Motif DE_48h DE_48h-Smad4_MA1153.2 7 bp overlap
Stat5a 1 dataset
Motif DE_48h DE_48h-Stat5a_MA1624.2 9 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 206 bp overlap
TCF7 2 datasets
Motif DE_48h DE_48h-TCF7_MA0769.3 7 bp overlap
Motif DE_60h DE_60h-TCF7_MA0769.3 7 bp overlap
TGIF1 2 datasets
Motif DE_36h DE_36h-TGIF1_MA0796.1 12 bp overlap
Motif DE_60h DE_60h-TGIF1_MA0796.1 12 bp overlap
TGIF2 2 datasets
Motif DE_36h DE_36h-TGIF2_MA0797.1 12 bp overlap
Motif DE_60h DE_60h-TGIF2_MA0797.1 12 bp overlap
TGIF2LX 2 datasets
Motif DE_36h DE_36h-TGIF2LX_MA1571.1 12 bp overlap
Motif DE_60h DE_60h-TGIF2LX_MA1571.1 12 bp overlap
TGIF2LY 2 datasets
Motif DE_36h DE_36h-TGIF2LY_MA1572.1 12 bp overlap
Motif DE_60h DE_60h-TGIF2LY_MA1572.1 12 bp overlap
TWIST1 2 datasets
Motif DE_36h DE_36h-TWIST1_MA1123.3 8 bp overlap
Motif DE_60h DE_60h-TWIST1_MA1123.3 8 bp overlap
ZBTB11 2 datasets
Motif DE_36h DE_36h-ZBTB11_MA2329.1 9 bp overlap
Motif DE_60h DE_60h-ZBTB11_MA2329.1 9 bp overlap
ZBTB12 3 datasets
Motif DE_36h DE_36h-ZBTB12_MA1649.2 7 bp overlap
Motif DE_60h DE_60h-ZBTB12_MA1649.2 7 bp overlap
Motif DE_60h DE_60h-ZBTB12_MA1649.2 7 bp overlap
ZBTB7A 2 datasets
Motif DE_36h DE_36h-ZBTB7A_MA0750.3 9 bp overlap
Motif DE_60h DE_60h-ZBTB7A_MA0750.3 9 bp overlap
ZIC4 2 datasets
Motif DE_36h DE_36h-ZIC4_MA0751.2 14 bp overlap
Motif DE_60h DE_60h-ZIC4_MA0751.2 14 bp overlap
ZNF135 2 datasets
Motif DE_48h DE_48h-ZNF135_MA1587.1 14 bp overlap
Motif DE_60h DE_60h-ZNF135_MA1587.1 14 bp overlap
ZNF157 2 datasets
Motif DE_48h DE_48h-ZNF157_MA2331.1 21 bp overlap
Motif DE_60h DE_60h-ZNF157_MA2331.1 21 bp overlap
ZNF189 1 dataset
Motif DE_60h DE_60h-ZNF189_MA1725.2 9 bp overlap
ZNF283 1 dataset
ChIP HEK293T GSE78099.ZNF283.HEK293T 157 bp overlap
ZNF317 1 dataset
Motif DE_48h DE_48h-ZNF317_MA1593.2 8 bp overlap
ZNF682 2 datasets
Motif DE_36h DE_36h-ZNF682_MA1599.2 11 bp overlap
Motif DE_60h DE_60h-ZNF682_MA1599.2 11 bp overlap
Zfx 2 datasets
Motif DE_48h DE_48h-Zfx_MA0146.3 10 bp overlap
Motif DE_60h DE_60h-Zfx_MA0146.3 10 bp overlap
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