chr10:101,282,747–101,283,297

chr10 : 101,282,747 – 101,283,297

550 bp 74 TFs 8 linked genes

This 550 bp open chromatin element is linked to 8 target genes and is bound by 74 transcription factors.

Linked Genes

8 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000289441		602 bp	At TSS	Proximity
BTRC		71.1 kb	Distal	Multiome
LZTS2		286.0 kb	Distal	Multiome
MRPL43		295.5 kb	Distal	Multiome
POLL		305.1 kb	Distal	Multiome+HiCAR
DPCD		305.3 kb	Distal	Multiome+HiCAR
FGF8		497.3 kb	Distal	Multiome+HiCAR
NPM3		500.4 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

74 transcription factors

BARX1 1 dataset

Motif DE_48h DE_48h-BARX1_MA0875.2 6 bp overlap

BARX2 1 dataset

Motif DE_48h DE_48h-BARX2_MA1471.2 9 bp overlap

BCOR 3 datasets

ChIP WA01 GSE104690.BCOR.WA01 186 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 358 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 111 bp overlap

BRD4 3 datasets

ChIP Kelly_resistant GSE103030.BRD4.Kelly_resistant 385 bp overlap

ChIP Kelly_resistant_JQ1 GSE103030.BRD4.Kelly_resistant_JQ1 300 bp overlap

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 358 bp overlap

Motif DE_48h DE_48h-BSX_MA0876.2 6 bp overlap

ChIP SCMC GSE155861.CHD4.SCMC 202 bp overlap

ChIP retina_Hu20 GSE137311.CRX.retina_Hu20 208 bp overlap

ChIP retina_Hu3 GSE137311.CRX.retina_Hu3 242 bp overlap

ChIP retina_Hu6 GSE137311.CRX.retina_Hu6 407 bp overlap

CTCF 3 datasets

ChIP retina_Hu22 GSE137311.CTCF.retina_Hu22 231 bp overlap

ChIP retina_Hu25 GSE137311.CTCF.retina_Hu25 272 bp overlap

ChIP retina_Hu6 GSE137311.CTCF.retina_Hu6 417 bp overlap

CTCFL 1 dataset

ChIP Kelly_resistant_JQ1 GSE103030.CTCFL.Kelly_resistant_JQ1 186 bp overlap

Motif DE_48h DE_48h-DLX1_MA0879.3 6 bp overlap

Motif DE_48h DE_48h-DLX6_MA0882.2 6 bp overlap

Motif DE_48h DE_48h-Dlx3_MA0880.2 6 bp overlap

Motif DE_48h DE_48h-Dlx4_MA0881.2 6 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 172 bp overlap

ESR1 6 datasets

ChIP MCF-7_E2_TNF GSE59530.ESR1.MCF-7_E2_TNF 152 bp overlap

ChIP breast-cancer_3487 GSE126004.ESR1.breast-cancer_3487 355 bp overlap

ChIP breast_tumor_Male_18 GSE104399.ESR1.breast_tumor_Male_18 257 bp overlap

ChIP breast_tumor_Male_26 GSE104399.ESR1.breast_tumor_Male_26 196 bp overlap

ChIP breast_tumor_Male_29 GSE104399.ESR1.breast_tumor_Male_29 295 bp overlap

ChIP breast_tumor_Male_5 GSE104399.ESR1.breast_tumor_Male_5 211 bp overlap

ESR1_Y537C 1 dataset

ChIP SUM44PE__ESR1_mutant_LTED GSE100074.ESR1_Y537C.SUM44PE__ESR1_mutant_LTED 285 bp overlap

EZH2 11 datasets

ChIP GM23338 ENCSR045YHA.EZH2.GM23338 418 bp overlap

ChIP HUVEC-C GSE109625.EZH2.HUVEC-C 177 bp overlap

ChIP SF8628 GSE94834.EZH2.SF8628 228 bp overlap

ChIP SF8628 GSE94834.EZH2.SF8628 192 bp overlap

ChIP SU-DHL-6_DMSO GSE134136.EZH2.SU-DHL-6_DMSO 355 bp overlap

ChIP WA01 ENCSR000ASY.EZH2.WA01 283 bp overlap

ChIP dermal-fibroblast_Untransformed GSE126396.EZH2.dermal-fibroblast_Untransformed 216 bp overlap

ChIP endothelial_umbilical-vein ENCSR000ATA.EZH2.endothelial_umbilical-vein 188 bp overlap

ChIP endothelial_umbilical-vein ENCSR000ATA.EZH2.endothelial_umbilical-vein 196 bp overlap

ChIP fibroblast_LUNG ENCSR000ARO.EZH2.fibroblast_LUNG 219 bp overlap

ChIP neural progenitor cell ENCFF018MKA 481 bp overlap

EZH2_phosphoT487 4 datasets

ChIP GM23248 ENCSR096KPA.EZH2_phosphoT487.GM23248 255 bp overlap

ChIP hepatocyte ENCSR341VYI.EZH2_phosphoT487.hepatocyte 51 bp overlap

ChIP neural_progenitor ENCSR656MXA.EZH2_phosphoT487.neural_progenitor 432 bp overlap

ChIP neuron_bipolar_doxy_4d ENCSR886KKK.EZH2_phosphoT487.neuron_bipolar_doxy_4d 303 bp overlap

FOXA1 5 datasets

ChIP MCF-7_E2_TNF GSE59530.FOXA1.MCF-7_E2_TNF 194 bp overlap

ChIP MCF-7_TNF GSE59530.FOXA1.MCF-7_TNF 136 bp overlap

ChIP breast-cancer_3487 GSE126004.FOXA1.breast-cancer_3487 388 bp overlap

ChIP breast_tumor_Male_13 GSE104399.FOXA1.breast_tumor_Male_13 169 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 413 bp overlap

FOXA2 3 datasets

ChIP DE DE-FOXA2-1 499 bp overlap

ChIP DE DE-FOXA2-2 479 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 387 bp overlap

GATA3 1 dataset

ChIP breast_tumor_Male_21 GSE104399.GATA3.breast_tumor_Male_21 305 bp overlap

GATA4 5 datasets

ChIP DE DE-GATA4-1 397 bp overlap

ChIP DE DE-GATA4-2 484 bp overlap

ChIP foregut GSE117136.GATA4.foregut 379 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 406 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 479 bp overlap

GATA6 12 datasets

ChIP DE DE-GATA6-1 427 bp overlap

ChIP DE DE-GATA6-2 462 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 326 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 419 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 380 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 306 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 333 bp overlap

ChIP foregut GSE117136.GATA6.foregut 447 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 362 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 431 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 483 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 386 bp overlap

Motif DE_48h DE_48h-GBX2_MA0890.2 6 bp overlap

GLIS1 2 datasets

ChIP HEK293 ENCFF299RSE 163 bp overlap

ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 350 bp overlap

HDAC2 1 dataset

ChIP WA01 ENCSR000AVB.HDAC2.WA01 228 bp overlap

HESX1 1 dataset

Motif DE_48h DE_48h-HESX1_MA0894.2 6 bp overlap

HNF1B 1 dataset

ChIP foregut GSE117136.HNF1B.foregut 382 bp overlap

HOXA7 1 dataset

Motif DE_48h DE_48h-HOXA7_MA1498.3 6 bp overlap

Motif DE_48h DE_48h-Hmx1_MA0896.2 9 bp overlap

Motif DE_48h DE_48h-Hmx3_MA0898.2 9 bp overlap

JARID2 1 dataset

ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 239 bp overlap

KDM1A 2 datasets

ChIP pancreatic-progenitor_PP1 GSE104840.KDM1A.pancreatic-progenitor_PP1 372 bp overlap

ChIP pancreatic-progenitor_PP2-KDM1A-inh GSE104840.KDM1A.pancreatic-progenitor_PP2-KDM1A-inh 247 bp overlap

ChIP HEK293_E419Q GSE88976.KLF5.HEK293_E419Q 306 bp overlap

Motif DE_48h DE_48h-LBX2_MA0699.2 6 bp overlap

Motif DE_48h DE_48h-LHX2_MA0700.3 6 bp overlap

MEF2D 1 dataset

ChIP retina_Hu13 GSE137311.MEF2D.retina_Hu13 251 bp overlap

Motif DE_48h DE_48h-MSX1_MA0666.3 6 bp overlap

Motif DE_48h DE_48h-MSX2_MA0708.3 6 bp overlap

ChIP Kelly GSE94822.MYCN.Kelly 129 bp overlap

Motif DE_48h DE_48h-Msx3_MA0709.2 6 bp overlap

NANOG 1 dataset

ChIP HUES-8 GSE109524.NANOG.HUES-8 431 bp overlap

NUTM1 1 dataset

ChIP embryonic-kidney_induced GSE133122.NUTM1.embryonic-kidney_induced 550 bp overlap

Nobox 1 dataset

Motif DE_48h DE_48h-Nobox_MA0125.2 6 bp overlap

ChIP retina_Hu7 GSE137311.OTX2.retina_Hu7 394 bp overlap

PDX1 4 datasets

ChIP hESC GSE58685.PDX1.hESC 179 bp overlap

ChIP hiPSC GSE125768.PDX1.hiPSC 342 bp overlap

ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 299 bp overlap

ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 370 bp overlap

PHOX2B 1 dataset

ChIP SK-N-BE2-C GSE94822.PHOX2B.SK-N-BE2-C 245 bp overlap

POU4F2 1 dataset

ChIP HNPC_DIF GSE74814.POU4F2.HNPC_DIF 160 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 320 bp overlap

Motif DE_48h DE_48h-RAX_MA0718.2 6 bp overlap

REST 2 datasets

ChIP PFSK1 ENCSR000BOX.REST.PFSK1 416 bp overlap

ChIP WA01 ENCSR000BHM.REST.WA01 123 bp overlap

ChIP WA09_heat-shock GSE105028.RNF2.WA09_heat-shock 208 bp overlap

ChIP retina_Hu22 GSE137311.RORB.retina_Hu22 403 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.RXR.pancreatic-progenitor_PP1 180 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 91 bp overlap

SIN3A 1 dataset

ChIP HUVEC-C GSE103245.SIN3A.HUVEC-C 173 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 457 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 302 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 380 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 340 bp overlap

SMARCA4 1 dataset

ChIP NSC GSE125033.SMARCA4.NSC 200 bp overlap

SMARCC1 1 dataset

ChIP hiPSC GSE124903.SMARCC1.hiPSC 246 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 349 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 400 bp overlap

SOX21 1 dataset

ChIP neuroepithelilal-cells GSE110505.SOX21.neuroepithelilal-cells 384 bp overlap

STAT3 1 dataset

ChIP breast-cancer_3487 GSE126004.STAT3.breast-cancer_3487 352 bp overlap

SUZ12 4 datasets

ChIP CRL-7250_shSS18-SSX GSE108025.SUZ12.CRL-7250_shSS18-SSX 550 bp overlap

ChIP H1 ENCFF881NFR 235 bp overlap

ChIP HEK293T_PCGF1352fl GSE119618.SUZ12.HEK293T_PCGF1352fl 259 bp overlap

ChIP HEK293T_PCGF1356fl GSE119618.SUZ12.HEK293T_PCGF1356fl 296 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 230 bp overlap

TOP2A 1 dataset

ChIP KG-1_etoposide GSE114048.TOP2A.KG-1_etoposide 101 bp overlap

ChIP WTC11 ENCFF359JCU 437 bp overlap

TRIM28 2 datasets

ChIP HEK293 ENCSR618HNF.TRIM28.HEK293 198 bp overlap

ChIP U2OS ENCSR000EYC.TRIM28.U2OS 198 bp overlap

ZIC2 2 datasets

ChIP HEK293 ENCFF033NQQ 242 bp overlap

ChIP HEK293 ENCFF033NQQ 216 bp overlap

ZNF18 1 dataset

ChIP HEK293 ENCSR977HTH.ZNF18.HEK293 189 bp overlap

ZNF263 2 datasets

ChIP HEK293 ENCFF336CWQ 199 bp overlap

ChIP HEK293T GSE78099.ZNF263.HEK293T 361 bp overlap

ZNF341 1 dataset

ChIP HEK293 ENCSR185FOY.ZNF341.HEK293 315 bp overlap

ZNF534 1 dataset

ChIP HEK293T GSE78099.ZNF534.HEK293T 64 bp overlap