chr11 : 108,219,058 – 108,219,457

399 bp 78 TFs 2 linked genes

This 399 bp open chromatin element is linked to NPAT and ATM and is bound by 78 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
NPAT		3.2 kb	Proximal	Proximity
ATM		3.3 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

78 transcription factors

ARNT::HIF1A 1 dataset

Motif DE_12h DE_12h-ARNTHIF1A_MA0259.2 5 bp overlap

ATF2 1 dataset

ChIP WA01 ENCSR000BQU.ATF2.WA01 187 bp overlap

BRD4 2 datasets

ChIP HEK293_sgNT GSE129407.BRD4.HEK293_sgNT 278 bp overlap

ChIP K-562_iBET-BD2-IFNG GSE138084.BRD4.K-562_iBET-BD2-IFNG 205 bp overlap

CREM 1 dataset

ChIP K-562 ENCSR077DKV.CREM.K-562 93 bp overlap

CXXC5 1 dataset

ChIP K562 ENCFF497CZN 399 bp overlap

EHMT2 2 datasets

ChIP K-562 ENCSR175EOM.EHMT2.K-562 243 bp overlap

ChIP K562 ENCFF053BWO 385 bp overlap

ELF1 2 datasets

ChIP K-562 ENCSR000BMD.ELF1.K-562 316 bp overlap

ChIP K562 ENCFF496AKI 277 bp overlap

ELK1::HOXA1 1 dataset

Motif DE_12h DE_12h-ELK1HOXA1_MA1931.1 14 bp overlap

EP400 1 dataset

ChIP K562 ENCFF850OZQ 78 bp overlap

ERF::HOXB13 1 dataset

Motif DE_12h DE_12h-ERFHOXB13_MA1937.2 13 bp overlap

ESR1_Y537N 1 dataset

ChIP MCF-7_dox_E2 GSE94493.ESR1_Y537N.MCF-7_dox_E2 104 bp overlap

ETS1 1 dataset

ChIP CTV-1_DSG GSE128835.ETS1.CTV-1_DSG 389 bp overlap

ETV2::DRGX 1 dataset

Motif DE_12h DE_12h-ETV2DRGX_MA1940.2 12 bp overlap

ETV2::FOXI1 1 dataset

Motif DE_12h DE_12h-ETV2FOXI1_MA1942.2 11 bp overlap

ETV5::DRGX 1 dataset

Motif DE_12h DE_12h-ETV5DRGX_MA1944.2 12 bp overlap

ETV5::HOXA2 2 datasets

Motif DE_12h DE_12h-ETV5HOXA2_MA1948.2 12 bp overlap

EWSR1-FLI1 1 dataset

Motif DE_12h DE_12h-EWSR1-FLI1_MA0149.1 18 bp overlap

FEZF2 1 dataset

Motif DE_12h DE_12h-FEZF2_MA2341.1 8 bp overlap

FLI1 1 dataset

ChIP CTV-1_DSG GSE128835.FLI1.CTV-1_DSG 271 bp overlap

FLI1::DRGX 1 dataset

Motif DE_12h DE_12h-FLI1DRGX_MA1949.2 14 bp overlap

FOSL1 2 datasets

ChIP K562 ENCFF455MKD 221 bp overlap

ChIP K562 ENCFF455MKD 399 bp overlap

FOXO1::ELF1 1 dataset

Motif DE_12h DE_12h-FOXO1ELF1_MA1953.2 13 bp overlap

FOXO1::ELK1 1 dataset

Motif DE_12h DE_12h-FOXO1ELK1_MA1954.2 13 bp overlap

HDAC1 1 dataset

ChIP K-562 ENCSR387UWP.HDAC1.K-562 289 bp overlap

HDGF 1 dataset

ChIP K-562 ENCSR197ALX.HDGF.K-562 350 bp overlap

HMBOX1 3 datasets

ChIP K-562 ENCSR757IIU.HMBOX1.K-562 369 bp overlap

ChIP K562 ENCFF055GAZ 399 bp overlap

ChIP K562 ENCFF317JJX 393 bp overlap

HOXB2::ELK1 1 dataset

Motif DE_12h DE_12h-HOXB2ELK1_MA1957.1 14 bp overlap

HOXB4 1 dataset

Motif DE_12h DE_12h-HOXB4_MA1499.2 6 bp overlap

HOXC4 1 dataset

Motif DE_12h DE_12h-HOXC4_MA1504.2 6 bp overlap

HOXD3 1 dataset

Motif DE_12h DE_12h-HOXD3_MA0912.2 8 bp overlap

HOXD4 1 dataset

Motif DE_12h DE_12h-HOXD4_MA1507.2 6 bp overlap

Hmx1 1 dataset

Motif DE_12h DE_12h-Hmx1_MA0896.2 9 bp overlap

Hmx2 1 dataset

Motif DE_12h DE_12h-Hmx2_MA0897.2 15 bp overlap

Hmx3 1 dataset

Motif DE_12h DE_12h-Hmx3_MA0898.2 9 bp overlap

IKZF2 2 datasets

Motif DE_12h DE_12h-IKZF2_MA2326.1 6 bp overlap

Lhx1 1 dataset

Motif DE_12h DE_12h-Lhx1_MA1518.3 10 bp overlap

MAX 1 dataset

ChIP K562 ENCFF524IJO 365 bp overlap

MNT 3 datasets

ChIP K-562 ENCSR390VGH.MNT.K-562 286 bp overlap

ChIP K562 ENCFF820IGH 366 bp overlap

ChIP K562 ENCFF820IGH 399 bp overlap

NANOG 3 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 242 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 187 bp overlap

ChIP hESC GSE18292.NANOG.hESC 111 bp overlap

NR2C1 3 datasets

ChIP K-562 ENCSR742IDN.NR2C1.K-562 201 bp overlap

ChIP K562 ENCFF239KMA 277 bp overlap

ChIP K562 ENCFF568JLK 183 bp overlap

NR2C2 2 datasets

ChIP K562 ENCFF750AXF 399 bp overlap

NR2F1 3 datasets

ChIP K-562 ENCSR970NKQ.NR2F1.K-562 263 bp overlap

ChIP K562 ENCFF221HJH 122 bp overlap

ChIP K562 ENCFF221HJH 399 bp overlap

NR2F2 2 datasets

ChIP K-562 ENCSR000BRS.NR2F2.K-562 282 bp overlap

ChIP K562 ENCFF004YPK 174 bp overlap

NR2F6 2 datasets

ChIP K-562 ENCSR707QWA.NR2F6.K-562 145 bp overlap

ChIP K562 ENCFF674RQA 201 bp overlap

Nanog 1 dataset

Motif DE_12h DE_12h-Nanog_MA2339.1 7 bp overlap

OSR2 2 datasets

ChIP HEK293 ENCFF875BDB 399 bp overlap

ChIP HEK293 ENCSR324LTM.OSR2.HEK293 282 bp overlap

PAX5 2 datasets

ChIP GM12878 ENCSR000BHJ.PAX5.GM12878 191 bp overlap

ChIP NALM-6 GSE126300.PAX5.NALM-6 171 bp overlap

PAX8 1 dataset

ChIP GM12878 ENCFF033MGF 119 bp overlap

PKNOX1 1 dataset

ChIP K-562 ENCSR115SMW.PKNOX1.K-562 275 bp overlap

POLR2A 3 datasets

ChIP H1 ENCFF566JSR 394 bp overlap

ChIP H1 ENCFF566JSR 399 bp overlap

ChIP H1 ENCFF833NJP 373 bp overlap

POU1F1 1 dataset

Motif DE_12h DE_12h-POU1F1_MA0784.3 14 bp overlap

POU2F1 1 dataset

Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap

POU2F2 1 dataset

Motif DE_12h DE_12h-POU2F2_MA0507.3 13 bp overlap

POU2F3 1 dataset

Motif DE_12h DE_12h-POU2F3_MA0627.3 9 bp overlap

POU3F1 1 dataset

Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap

POU3F2 1 dataset

Motif DE_12h DE_12h-POU3F2_MA0787.1 12 bp overlap

POU3F3 1 dataset

Motif DE_12h DE_12h-POU3F3_MA0788.1 13 bp overlap

POU3F4 1 dataset

Motif DE_12h DE_12h-POU3F4_MA0789.1 9 bp overlap

POU5F1 1 dataset

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 338 bp overlap

POU5F1B 1 dataset

Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap

POU6F1 1 dataset

Motif DE_12h DE_12h-POU6F1_MA1549.2 7 bp overlap

PRDM9 1 dataset

Motif DE_12h DE_12h-PRDM9_MA1723.2 20 bp overlap

PROX1 1 dataset

Motif DE_12h DE_12h-PROX1_MA0794.1 12 bp overlap

RFX7 1 dataset

Motif DE_12h DE_12h-RFX7_MA1554.2 8 bp overlap

SIN3A 1 dataset

ChIP WA01 ENCSR000EBO.SIN3A.WA01 128 bp overlap

SMARCA4 3 datasets

ChIP CTV-1_DSG GSE128835.SMARCA4.CTV-1_DSG 354 bp overlap

ChIP CTV-1_FLAG GSE128835.SMARCA4.CTV-1_FLAG 196 bp overlap

ChIP endometrial-epithelial-cells_KO GSE106660.SMARCA4.endometrial-epithelial-cells_KO 260 bp overlap

SPI1 5 datasets

ChIP CTV-1_FLAG_15perc GSE128835.SPI1.CTV-1_FLAG_15perc 277 bp overlap

ChIP CTV-1_delQ GSE128835.SPI1.CTV-1_delQ 220 bp overlap

ChIP K-562 GSE70482.SPI1.K-562 207 bp overlap

ChIP K-562 ENCSR000BGW.SPI1.K-562 130 bp overlap

ChIP K-562_NABUT GSE74999.SPI1.K-562_NABUT 151 bp overlap

SPIB 1 dataset

Motif DE_12h DE_12h-SPIB_MA0081.3 13 bp overlap

STAT1_pS727 1 dataset

ChIP SET-2 GSE100566.STAT1_pS727.SET-2 393 bp overlap

Spi1 1 dataset

Motif DE_12h DE_12h-Spi1_MA0080.7 13 bp overlap

TRIM28 1 dataset

ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 154 bp overlap

YY1 4 datasets

ChIP H1 ENCFF524BTL 337 bp overlap

ChIP K-562 ENCSR000BMH.YY1.K-562 209 bp overlap

ChIP K562 ENCFF660QRE 311 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 166 bp overlap

ZKSCAN1 1 dataset

Motif DE_12h DE_12h-ZKSCAN1_MA1585.2 9 bp overlap

ZNF143 1 dataset

ChIP FLP76_T4 GSE39263.ZNF143.FLP76_T4 230 bp overlap

ZNF214 1 dataset

Motif DE_12h DE_12h-ZNF214_MA1975.2 13 bp overlap

ZNF592 1 dataset

ChIP K-562 ENCSR249BHQ.ZNF592.K-562 275 bp overlap

ZNF701 1 dataset

Motif DE_12h DE_12h-ZNF701_MA1987.2 17 bp overlap

ZSCAN5C 1 dataset

ChIP HEK293 ENCSR731AGO.ZSCAN5C.HEK293 74 bp overlap