Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

31 transcription factors

ARID1A 1 dataset

ChIP 12Z GSE129781.ARID1A.12Z 268 bp overlap

CHD7 1 dataset

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 406 bp overlap

ESR1 2 datasets

ChIP MCF-7_E2+4OHT_SRC-3 GSE119702.ESR1.MCF-7_E2+4OHT_SRC-3 166 bp overlap

ChIP MCF-7_SRC3_OHT GSE119702.ESR1.MCF-7_SRC3_OHT 166 bp overlap

EZH2 1 dataset

ChIP hepatocyte ENCFF118DKH 339 bp overlap

EZH2_phosphoT487 1 dataset

ChIP hepatocyte ENCSR341VYI.EZH2_phosphoT487.hepatocyte 256 bp overlap

FOXA1 1 dataset

ChIP liver ERP002306.FOXA1.liver 125 bp overlap

FOXA2 4 datasets

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 195 bp overlap

ChIP Caco-2 GSE66218.FOXA2.Caco-2 148 bp overlap

ChIP DE DE-FOXA2-1 396 bp overlap

ChIP DE DE-FOXA2-2 419 bp overlap

FOXL2 4 datasets

ChIP HGrC1_C134W-TGF GSE138496.FOXL2.HGrC1_C134W-TGF 419 bp overlap

ChIP HGrC1_C134W-TGF_parental GSE138496.FOXL2.HGrC1_C134W-TGF_parental 315 bp overlap

ChIP KGN_1512 GSE138496.FOXL2.KGN_1512 169 bp overlap

ChIP KGN_1513 GSE138496.FOXL2.KGN_1513 293 bp overlap

GATA1 2 datasets

ChIP K-562 GSE107726.GATA1.K-562 208 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 146 bp overlap

GATA2 1 dataset

ChIP dermal-fibroblast_alone GSE51025.GATA2.dermal-fibroblast_alone 212 bp overlap

GATA3 1 dataset

ChIP SK-N-SH ENCFF040SSB 320 bp overlap

GATA4 6 datasets

ChIP DE DE-GATA4-1 419 bp overlap

ChIP DE DE-GATA4-2 419 bp overlap

ChIP Hep-G2 GSE135714.GATA4.Hep-G2 419 bp overlap

ChIP foregut GSE117136.GATA4.foregut 383 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 419 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 346 bp overlap

GATA6 15 datasets

ChIP AGS GSE51705.GATA6.AGS 366 bp overlap

ChIP AGS GSE51936.GATA6.AGS 137 bp overlap

ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 167 bp overlap

ChIP DE DE-GATA6-1 406 bp overlap

ChIP DE DE-GATA6-2 419 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 409 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 358 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 419 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 380 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 409 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 388 bp overlap

ChIP foregut GSE117136.GATA6.foregut 387 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 337 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 238 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 327 bp overlap

HAND2 1 dataset

ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 223 bp overlap

IKZF1 1 dataset

ChIP pre-B-cell GSE107886.IKZF1.pre-B-cell 228 bp overlap

JUND 1 dataset

ChIP liver ENCSR837GTK.JUND.liver 177 bp overlap

ONECUT1 1 dataset

ChIP liver ERP002306.ONECUT1.liver 167 bp overlap

ONECUT2 2 datasets

ChIP A-549 GSE102599.ONECUT2.A-549 328 bp overlap

ChIP PC-3_normoxia GSE106305.ONECUT2.PC-3_normoxia 180 bp overlap

OSR2 3 datasets

ChIP HEK293 ENCFF875BDB 356 bp overlap

ChIP HEK293 ENCSR324LTM.OSR2.HEK293 269 bp overlap

ChIP HEK293 GSE76494.OSR2.HEK293 197 bp overlap

PGR 1 dataset

ChIP leiomyoma_RU486 GSE40724.PGR.leiomyoma_RU486 103 bp overlap

RBFOX2 1 dataset

ChIP K-562 GSE120104.RBFOX2.K-562 186 bp overlap

RCOR1 1 dataset

ChIP IMR-90 ENCSR000EFG.RCOR1.IMR-90 85 bp overlap

SMAD2-3 4 datasets

ChIP HGrC1_C134W-TGF GSE138496.SMAD2-3.HGrC1_C134W-TGF 276 bp overlap

ChIP HGrC1_C134W-TGF_SMAD4-KO GSE138496.SMAD2-3.HGrC1_C134W-TGF_SMAD4-KO 85 bp overlap

ChIP HGrC1_WT-TGF GSE138496.SMAD2-3.HGrC1_WT-TGF 113 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 419 bp overlap

SMAD2_3 1 dataset

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 229 bp overlap

SMAD4 3 datasets

ChIP Caco-2 GSE112946.SMAD4.Caco-2 212 bp overlap

ChIP HGrC1_C134W-TGF GSE138496.SMAD4.HGrC1_C134W-TGF 208 bp overlap

ChIP HGrC1_C134W-TGF_parental GSE138496.SMAD4.HGrC1_C134W-TGF_parental 63 bp overlap

SMARCA2 2 datasets

ChIP NPC_K755R-siCT GSE122631.SMARCA2.NPC_K755R-siCT 120 bp overlap

ChIP NPC_R1159Q_AM GSE122631.SMARCA2.NPC_R1159Q_AM 138 bp overlap

SMARCA4 7 datasets

ChIP A-549_AG15678 GSE132290.SMARCA4.A-549_AG15678 59 bp overlap

ChIP A-549_AG15720 GSE132290.SMARCA4.A-549_AG15720 72 bp overlap

ChIP A-549_AG15722 GSE132290.SMARCA4.A-549_AG15722 53 bp overlap

ChIP A-549_AG15725 GSE132290.SMARCA4.A-549_AG15725 86 bp overlap

ChIP NPC_K755R-siAP GSE122631.SMARCA4.NPC_K755R-siAP 294 bp overlap

ChIP NPC_K755R-siCT GSE122631.SMARCA4.NPC_K755R-siCT 283 bp overlap

ChIP NPC_siSOX GSE122631.SMARCA4.NPC_siSOX 271 bp overlap

SMC3 1 dataset

ChIP HeLa-Kyoto_WAPL_PDS-depleted GSE102884.SMC3.HeLa-Kyoto_WAPL_PDS-depleted 154 bp overlap

SOX2 1 dataset

ChIP HNSC GSE69479.SOX2.HNSC 419 bp overlap

ZFP64 1 dataset

ChIP HEK293 GSE76494.ZFP64.HEK293 147 bp overlap

ZNF479 1 dataset

ChIP HEK293T GSE78099.ZNF479.HEK293T 256 bp overlap

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000253284		7.0 kb	Proximal	Proximity
PLEKHA5		9.9 kb	Proximal	Proximity

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