chr12 : 22,924,088 – 22,924,950
862 bp 60 TFs 3 linked genes
This 862 bp open chromatin element is linked to ENSG00000256923, LINC02955, and ETNK1 and is bound by 60 transcription factors.
Linked Genes
3 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000256923 181.9 kb Distal Multiome
LINC02955 224.6 kb Distal Multiome
ETNK1 299.4 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr12:22,919,088 – 22,929,950
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
60 transcription factors
Source
Cell type
BCL6B 2 datasets
Motif DE_12h DE_12h-BCL6B_MA0731.1 17 bp overlap
Motif DE_24h DE_24h-BCL6B_MA0731.1 17 bp overlap
CTCF 20 datasets
ChIP 22Rv1 ENCFF466OXN 639 bp overlap
ChIP C4-2B ENCFF821XVN 765 bp overlap
Motif DE_12h DE_12h-CTCF_MA0139.2 15 bp overlap
Motif DE_12h DE_12h-CTCF_MA1929.2 31 bp overlap
Motif DE_12h DE_12h-CTCF_MA1930.2 33 bp overlap
Motif DE_24h DE_24h-CTCF_MA0139.2 15 bp overlap
Motif DE_24h DE_24h-CTCF_MA1929.2 31 bp overlap
Motif DE_24h DE_24h-CTCF_MA1930.2 33 bp overlap
Motif DE_36h DE_36h-CTCF_MA0139.2 15 bp overlap
Motif DE_36h DE_36h-CTCF_MA1929.2 31 bp overlap
Motif DE_36h DE_36h-CTCF_MA1930.2 33 bp overlap
Motif DE_48h DE_48h-CTCF_MA0139.2 15 bp overlap
Motif DE_48h DE_48h-CTCF_MA1929.2 31 bp overlap
Motif DE_48h DE_48h-CTCF_MA1930.2 33 bp overlap
Motif DE_60h DE_60h-CTCF_MA0139.2 15 bp overlap
ChIP HCT116 ENCFF209YMI 285 bp overlap
ChIP THP-1_Pam3csk-150m-Flavo-030m GSE103477.CTCF.THP-1_Pam3csk-150m-Flavo-030m 162 bp overlap
ChIP endodermal cell ENCFF471YCZ 229 bp overlap
ChIP epithelial cell of proximal tubule ENCFF763ZKS 331 bp overlap
ChIP keratinocyte ENCFF667ULX 325 bp overlap
CUX1 2 datasets
Motif DE_12h DE_12h-CUX1_MA0754.3 9 bp overlap
Motif DE_24h DE_24h-CUX1_MA0754.3 9 bp overlap
CUX2 2 datasets
Motif DE_12h DE_12h-CUX2_MA0755.2 9 bp overlap
Motif DE_24h DE_24h-CUX2_MA0755.2 9 bp overlap
E2F7 2 datasets
Motif DE_24h DE_24h-E2F7_MA0758.1 14 bp overlap
Motif DE_48h DE_48h-E2F7_MA0758.1 14 bp overlap
EHF 3 datasets
Motif DE_12h DE_12h-EHF_MA0598.4 9 bp overlap
Motif DE_24h DE_24h-EHF_MA0598.4 9 bp overlap
Motif DE_48h DE_48h-EHF_MA0598.4 9 bp overlap
ELF3 3 datasets
Motif DE_12h DE_12h-ELF3_MA0640.3 9 bp overlap
Motif DE_24h DE_24h-ELF3_MA0640.3 9 bp overlap
Motif DE_48h DE_48h-ELF3_MA0640.3 9 bp overlap
Elf5 3 datasets
Motif DE_12h DE_12h-Elf5_MA0136.4 8 bp overlap
Motif DE_24h DE_24h-Elf5_MA0136.4 8 bp overlap
Motif DE_48h DE_48h-Elf5_MA0136.4 8 bp overlap
Erg 3 datasets
Motif DE_12h DE_12h-Erg_MA0474.4 10 bp overlap
Motif DE_24h DE_24h-Erg_MA0474.4 10 bp overlap
Motif DE_48h DE_48h-Erg_MA0474.4 10 bp overlap
FIGLA 5 datasets
Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap
Motif DE_24h DE_24h-FIGLA_MA0820.2 6 bp overlap
Motif DE_36h DE_36h-FIGLA_MA0820.2 6 bp overlap
Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap
Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 438 bp overlap
ChIP DE DE-FOXA2-2 472 bp overlap
GABPA 3 datasets
Motif DE_12h DE_12h-GABPA_MA0062.4 10 bp overlap
Motif DE_24h DE_24h-GABPA_MA0062.4 10 bp overlap
Motif DE_48h DE_48h-GABPA_MA0062.4 10 bp overlap
GATA1::TAL1 9 datasets
Motif DE_12h DE_12h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_12h DE_12h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_24h DE_24h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_24h DE_24h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_36h DE_36h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_36h DE_36h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap
Motif DE_60h DE_60h-GATA1TAL1_MA0140.3 17 bp overlap
GATA2 3 datasets
Motif DE_12h DE_12h-GATA2_MA0036.4 7 bp overlap
Motif DE_24h DE_24h-GATA2_MA0036.4 7 bp overlap
Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap
GATA4 12 datasets
ChIP DE DE-GATA4-1 564 bp overlap
ChIP DE DE-GATA4-2 613 bp overlap
Motif DE_12h DE_12h-GATA4_MA0482.3 8 bp overlap
Motif DE_12h DE_12h-GATA4_MA0482.3 8 bp overlap
Motif DE_24h DE_24h-GATA4_MA0482.3 8 bp overlap
Motif DE_24h DE_24h-GATA4_MA0482.3 8 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 341 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 575 bp overlap
GATA5 8 datasets
Motif DE_12h DE_12h-GATA5_MA0766.3 8 bp overlap
Motif DE_12h DE_12h-GATA5_MA0766.3 8 bp overlap
Motif DE_24h DE_24h-GATA5_MA0766.3 8 bp overlap
Motif DE_24h DE_24h-GATA5_MA0766.3 8 bp overlap
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
GATA6 21 datasets
ChIP DE DE-GATA6-1 549 bp overlap
ChIP DE DE-GATA6-2 653 bp overlap
Motif DE_12h DE_12h-GATA6_MA1104.3 8 bp overlap
Motif DE_12h DE_12h-GATA6_MA1104.3 8 bp overlap
Motif DE_12h DE_12h-GATA6_MA1104.3 8 bp overlap
Motif DE_24h DE_24h-GATA6_MA1104.3 8 bp overlap
Motif DE_24h DE_24h-GATA6_MA1104.3 8 bp overlap
Motif DE_24h DE_24h-GATA6_MA1104.3 8 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 632 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 646 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 640 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 857 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 424 bp overlap
ChIP foregut GSE117136.GATA6.foregut 264 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 294 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 296 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 463 bp overlap
Gata3 10 datasets
Motif DE_12h DE_12h-Gata3_MA0037.5 8 bp overlap
Motif DE_12h DE_12h-Gata3_MA0037.5 8 bp overlap
Motif DE_12h DE_12h-Gata3_MA0037.5 8 bp overlap
Motif DE_24h DE_24h-Gata3_MA0037.5 8 bp overlap
Motif DE_24h DE_24h-Gata3_MA0037.5 8 bp overlap
Motif DE_24h DE_24h-Gata3_MA0037.5 8 bp overlap
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
HAND2 4 datasets
Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap
Motif DE_24h DE_24h-HAND2_MA1638.2 6 bp overlap
Motif DE_36h DE_36h-HAND2_MA1638.2 6 bp overlap
Motif DE_48h DE_48h-HAND2_MA1638.2 6 bp overlap
HOXB13 1 dataset
ChIP prostate_P5_T GSE130408.HOXB13.prostate_P5_T 55 bp overlap
Hand1 2 datasets
Motif DE_12h DE_12h-Hand1_MA2123.1 9 bp overlap
Motif DE_48h DE_48h-Hand1_MA2123.1 9 bp overlap
Hand1::Tcf3 5 datasets
Motif DE_12h DE_12h-Hand1Tcf3_MA0092.2 9 bp overlap
Motif DE_24h DE_24h-Hand1Tcf3_MA0092.2 9 bp overlap
Motif DE_36h DE_36h-Hand1Tcf3_MA0092.2 9 bp overlap
Motif DE_48h DE_48h-Hand1Tcf3_MA0092.2 9 bp overlap
Motif DE_60h DE_60h-Hand1Tcf3_MA0092.2 9 bp overlap
IRF3 3 datasets
Motif DE_12h DE_12h-IRF3_MA1418.2 17 bp overlap
Motif DE_24h DE_24h-IRF3_MA1418.2 17 bp overlap
Motif DE_48h DE_48h-IRF3_MA1418.2 17 bp overlap
JUN 2 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 315 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 351 bp overlap
MITF 3 datasets
ChIP 501-mel GSE137522.MITF.501-mel 345 bp overlap
ChIP 501-mel_20ng_K243R GSE137522.MITF.501-mel_20ng_K243R 336 bp overlap
ChIP K-562 ENCSR797SWM.MITF.K-562 204 bp overlap
Mecom 1 dataset
Motif DE_24h DE_24h-Mecom_MA0029.2 11 bp overlap
NANOG 3 datasets
ChIP HUES-8 GSE109524.NANOG.HUES-8 460 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 483 bp overlap
ChIP hESC GSE18292.NANOG.hESC 93 bp overlap
NFATC3 2 datasets
Motif DE_12h DE_12h-NFATC3_MA0625.3 6 bp overlap
Motif DE_48h DE_48h-NFATC3_MA0625.3 6 bp overlap
NFIB 3 datasets
Motif DE_12h DE_12h-NFIB_MA1643.2 17 bp overlap
Motif DE_24h DE_24h-NFIB_MA1643.2 17 bp overlap
Motif DE_48h DE_48h-NFIB_MA1643.2 17 bp overlap
Nfatc1 2 datasets
Motif DE_12h DE_12h-Nfatc1_MA0624.3 6 bp overlap
Motif DE_48h DE_48h-Nfatc1_MA0624.3 6 bp overlap
Nfatc2 3 datasets
Motif DE_12h DE_12h-Nfatc2_MA0152.3 8 bp overlap
Motif DE_24h DE_24h-Nfatc2_MA0152.3 8 bp overlap
Motif DE_48h DE_48h-Nfatc2_MA0152.3 8 bp overlap
ONECUT1 3 datasets
Motif DE_12h DE_12h-ONECUT1_MA0679.3 9 bp overlap
Motif DE_24h DE_24h-ONECUT1_MA0679.3 9 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.ONECUT1.pancreatic-progenitor_PP1 539 bp overlap
ONECUT2 2 datasets
Motif DE_12h DE_12h-ONECUT2_MA0756.3 8 bp overlap
Motif DE_24h DE_24h-ONECUT2_MA0756.3 8 bp overlap
PGR 3 datasets
Motif DE_12h DE_12h-PGR_MA2327.1 9 bp overlap
Motif DE_24h DE_24h-PGR_MA2327.1 9 bp overlap
Motif DE_48h DE_48h-PGR_MA2327.1 9 bp overlap
POU2F1::SOX2 4 datasets
Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif DE_24h DE_24h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif DE_36h DE_36h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif DE_48h DE_48h-POU2F1SOX2_MA1962.1 17 bp overlap
POU5F1 4 datasets
ChIP DE_D1 DED1-OCT4_Batch_II 455 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 555 bp overlap
ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 299 bp overlap
ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 468 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 386 bp overlap
PRDM9 3 datasets
Motif DE_12h DE_12h-PRDM9_MA1723.2 20 bp overlap
Motif DE_24h DE_24h-PRDM9_MA1723.2 20 bp overlap
Motif DE_48h DE_48h-PRDM9_MA1723.2 20 bp overlap
Pou5f1::Sox2 4 datasets
Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif DE_24h DE_24h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif DE_36h DE_36h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif DE_48h DE_48h-Pou5f1Sox2_MA0142.1 15 bp overlap
Prdm15 2 datasets
Motif DE_12h DE_12h-Prdm15_MA1616.2 11 bp overlap
Motif DE_24h DE_24h-Prdm15_MA1616.2 11 bp overlap
RBPJ 3 datasets
Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap
Motif DE_24h DE_24h-RBPJ_MA1116.2 6 bp overlap
Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap
SALL3 1 dataset
ChIP hiPSC GSE104863.SALL3.hiPSC 267 bp overlap
SMAD2 7 datasets
Motif DE_12h DE_12h-SMAD2_MA1964.2 6 bp overlap
Motif DE_24h DE_24h-SMAD2_MA1964.2 6 bp overlap
Motif DE_36h DE_36h-SMAD2_MA1964.2 6 bp overlap
Motif DE_48h DE_48h-SMAD2_MA1964.2 6 bp overlap
Motif DE_60h DE_60h-SMAD2_MA1964.2 6 bp overlap
ChIP endoderm GSE29422.SMAD2.endoderm 133 bp overlap
ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 441 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 840 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 862 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 769 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 862 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 862 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 148 bp overlap
SMARCA4 2 datasets
ChIP hiPSC GSE124903.SMARCA4.hiPSC 301 bp overlap
ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 172 bp overlap
SMARCC1 1 dataset
ChIP DE_D1 S15-DE-d1-BAF155-exp1 653 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 297 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 349 bp overlap
SPIB 3 datasets
Motif DE_12h DE_12h-SPIB_MA0081.3 13 bp overlap
Motif DE_24h DE_24h-SPIB_MA0081.3 13 bp overlap
Motif DE_48h DE_48h-SPIB_MA0081.3 13 bp overlap
Smad4 3 datasets
Motif DE_12h DE_12h-Smad4_MA1153.2 7 bp overlap
Motif DE_24h DE_24h-Smad4_MA1153.2 7 bp overlap
Motif DE_48h DE_48h-Smad4_MA1153.2 7 bp overlap
Spi1 3 datasets
Motif DE_12h DE_12h-Spi1_MA0080.7 13 bp overlap
Motif DE_24h DE_24h-Spi1_MA0080.7 13 bp overlap
Motif DE_48h DE_48h-Spi1_MA0080.7 13 bp overlap
TRPS1 10 datasets
Motif DE_12h DE_12h-TRPS1_MA1970.2 8 bp overlap
Motif DE_12h DE_12h-TRPS1_MA1970.2 8 bp overlap
Motif DE_12h DE_12h-TRPS1_MA1970.2 8 bp overlap
Motif DE_24h DE_24h-TRPS1_MA1970.2 8 bp overlap
Motif DE_24h DE_24h-TRPS1_MA1970.2 8 bp overlap
Motif DE_24h DE_24h-TRPS1_MA1970.2 8 bp overlap
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
USF1 2 datasets
ChIP H1 ENCFF090WVU 241 bp overlap
ChIP WA01 ENCSR000BIU.USF1.WA01 225 bp overlap
ZEB1 5 datasets
Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap
Motif DE_24h DE_24h-ZEB1_MA0103.4 6 bp overlap
Motif DE_36h DE_36h-ZEB1_MA0103.4 6 bp overlap
Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap
Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap
ZNF135 4 datasets
Motif DE_12h DE_12h-ZNF135_MA1587.1 14 bp overlap
Motif DE_24h DE_24h-ZNF135_MA1587.1 14 bp overlap
Motif DE_36h DE_36h-ZNF135_MA1587.1 14 bp overlap
Motif DE_48h DE_48h-ZNF135_MA1587.1 14 bp overlap
ZNF530 3 datasets
Motif DE_12h DE_12h-ZNF530_MA1981.2 14 bp overlap
Motif DE_24h DE_24h-ZNF530_MA1981.2 14 bp overlap
Motif DE_48h DE_48h-ZNF530_MA1981.2 14 bp overlap
ZNF558 2 datasets
Motif DE_12h DE_12h-ZNF558_MA2335.1 29 bp overlap
Motif DE_24h DE_24h-ZNF558_MA2335.1 29 bp overlap
ZNF75A 3 datasets
Motif DE_12h DE_12h-ZNF75A_MA2097.1 12 bp overlap
Motif DE_24h DE_24h-ZNF75A_MA2097.1 12 bp overlap
Motif DE_48h DE_48h-ZNF75A_MA2097.1 12 bp overlap
ZSCAN22 1 dataset
ChIP HEK293 GSE76494.ZSCAN22.HEK293 214 bp overlap
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