chr13 : 33,755,212 – 33,756,041

829 bp 55 TFs 2 linked genes

This 829 bp open chromatin element is linked to RFC3 and ENSG00000276672 and is bound by 55 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
RFC3		62.4 kb	Distal	Multiome
ENSG00000276672		90.5 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

55 transcription factors

AR 2 datasets

ChIP 22Rv1_pLKO GSE109748.AR.22Rv1_pLKO 182 bp overlap

ChIP VCaP_DHT24H_SHFOXP1 GSE58428.AR.VCaP_DHT24H_SHFOXP1 150 bp overlap

BCL6B 1 dataset

Motif DE_48h DE_48h-BCL6B_MA0731.1 17 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF093OYK 240 bp overlap

EOMES 3 datasets

Motif DE_48h DE_48h-EOMES_MA0800.2 9 bp overlap

ChIP hESC GSE26097.EOMES.hESC 139 bp overlap

ChIP hESC GSE26097.EOMES.hESC 546 bp overlap

ESR1 1 dataset

ChIP Ishikawa_M1-9-1 GSE147141.ESR1.Ishikawa_M1-9-1 256 bp overlap

FOXA1 1 dataset

ChIP VCaP_DHT24H GSE58428.FOXA1.VCaP_DHT24H 62 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 484 bp overlap

ChIP DE DE-FOXA2-2 544 bp overlap

FOXH1 2 datasets

Motif DE_48h DE_48h-FOXH1_MA0479.2 8 bp overlap

Motif DE_60h DE_60h-FOXH1_MA0479.2 8 bp overlap

FOXO1-PAX3 1 dataset

ChIP RH4_DMSO-6H GSE116344.FOXO1-PAX3.RH4_DMSO-6H 251 bp overlap

GATA2 1 dataset

ChIP dermal-fibroblast_alone GSE51025.GATA2.dermal-fibroblast_alone 50 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 498 bp overlap

ChIP DE DE-GATA4-2 589 bp overlap

GATA6 8 datasets

ChIP DE DE-GATA6-1 459 bp overlap

ChIP DE DE-GATA6-2 494 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 705 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 785 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 579 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 829 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 723 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 442 bp overlap

HOXB4 1 dataset

Motif DE_48h DE_48h-HOXB4_MA1499.2 6 bp overlap

HOXC4 1 dataset

Motif DE_48h DE_48h-HOXC4_MA1504.2 6 bp overlap

HOXD4 1 dataset

Motif DE_48h DE_48h-HOXD4_MA1507.2 6 bp overlap

JDP2 2 datasets

Motif DE_48h DE_48h-JDP2_MA0655.1 9 bp overlap

Motif DE_60h DE_60h-JDP2_MA0655.1 9 bp overlap

JUN 5 datasets

ChIP DE_D1 S08-DE-d1-JUN-exp1 268 bp overlap

ChIP DE_D1 S13-DE-d1-JUN-exp1 278 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 545 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 255 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 370 bp overlap

MGA::EVX1 1 dataset

Motif DE_48h DE_48h-MGAEVX1_MA1960.2 11 bp overlap

NFE2 2 datasets

Motif DE_48h DE_48h-NFE2_MA0841.2 10 bp overlap

Motif DE_60h DE_60h-NFE2_MA0841.2 10 bp overlap

NKX6-1 1 dataset

Motif DE_48h DE_48h-NKX6-1_MA0674.2 7 bp overlap

NKX6-3 1 dataset

Motif DE_48h DE_48h-NKX6-3_MA1530.2 8 bp overlap

NUTM1 1 dataset

ChIP embryonic-kidney_induced GSE133122.NUTM1.embryonic-kidney_induced 304 bp overlap

POU2F1 1 dataset

Motif DE_48h DE_48h-POU2F1_MA0785.2 9 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_48h DE_48h-POU2F1SOX2_MA1962.1 17 bp overlap

POU3F1 1 dataset

Motif DE_48h DE_48h-POU3F1_MA0786.2 10 bp overlap

POU3F4 1 dataset

Motif DE_48h DE_48h-POU3F4_MA0789.1 9 bp overlap

POU5F1B 1 dataset

Motif DE_48h DE_48h-POU5F1B_MA0792.1 9 bp overlap

POU6F1 1 dataset

Motif DE_48h DE_48h-POU6F1_MA1549.2 7 bp overlap

POU6F2 1 dataset

Motif DE_48h DE_48h-POU6F2_MA0793.2 9 bp overlap

PRDM1 1 dataset

Motif DE_48h DE_48h-PRDM1_MA0508.4 7 bp overlap

PROX1 1 dataset

Motif DE_48h DE_48h-PROX1_MA0794.1 12 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_48h DE_48h-Pou5f1Sox2_MA0142.1 15 bp overlap

RUNX1 1 dataset

ChIP VCaP_DHT24H GSE58428.RUNX1.VCaP_DHT24H 101 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 463 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 829 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 646 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 509 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 607 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 540 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 569 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 409 bp overlap

SMAD4 1 dataset

ChIP HGrC1_EV GSE138496.SMAD4.HGrC1_EV 91 bp overlap

SMARCC1 1 dataset

ChIP DE_D1 S15-DE-d1-BAF155-exp1 302 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 270 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 748 bp overlap

SOX8 1 dataset

ChIP RH4_Entinostat-6H GSE116344.SOX8.RH4_Entinostat-6H 264 bp overlap

SPI1 1 dataset

ChIP CD34_FETAL GSE70660.SPI1.CD34_FETAL 195 bp overlap

SPIC 1 dataset

Motif DE_48h DE_48h-SPIC_MA0687.2 13 bp overlap

Stat4 1 dataset

Motif DE_48h DE_48h-Stat4_MA0518.2 10 bp overlap

T 1 dataset

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 251 bp overlap

TBR1 1 dataset

Motif DE_48h DE_48h-TBR1_MA0802.2 9 bp overlap

TBX2 1 dataset

Motif DE_48h DE_48h-TBX2_MA0688.2 9 bp overlap

TBX3 1 dataset

Motif DE_48h DE_48h-TBX3_MA1566.3 9 bp overlap

TBX5 1 dataset

ChIP G296S_4 GSE85628.TBX5.G296S_4 576 bp overlap

ZKSCAN5 2 datasets

Motif DE_48h DE_48h-ZKSCAN5_MA1652.2 9 bp overlap

Motif DE_60h DE_60h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF143 1 dataset

ChIP FLP143HA_T4 GSE39263.ZNF143.FLP143HA_T4 145 bp overlap

ZNF184 2 datasets

Motif DE_48h DE_48h-ZNF184_MA2120.1 13 bp overlap

Motif DE_60h DE_60h-ZNF184_MA2120.1 13 bp overlap

ZNF317 1 dataset

ChIP HEK293 GSE76494.ZNF317.HEK293 77 bp overlap

ZNF354C 2 datasets

Motif DE_48h DE_48h-ZNF354C_MA0130.1 6 bp overlap

Motif DE_60h DE_60h-ZNF354C_MA0130.1 6 bp overlap

ZNF652 1 dataset

Motif DE_48h DE_48h-ZNF652_MA1657.2 9 bp overlap

ZNF768 1 dataset

Motif DE_48h DE_48h-ZNF768_MA1731.2 9 bp overlap