chr14:52,827,263–52,828,172

chr14 : 52,827,263 – 52,828,172

909 bp 103 TFs 8 linked genes

This 909 bp open chromatin element is linked to 8 target genes and is bound by 103 transcription factors.

Linked Genes

8 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000285664		35.9 kb	Distal	Multiome
GNPNAT1		36.0 kb	Distal	Multiome
STYX		97.5 kb	Distal	Multiome
PSMC6		120.4 kb	Distal	Multiome
FERMT2		123.4 kb	Distal	Multiome+HiCAR
ERO1A		131.7 kb	Distal	Multiome
GPR137C		274.8 kb	Distal	Multiome
TXNDC16		275.1 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

103 transcription factors

ARNTL 1 dataset

ChIP U2OS GSE44236.ARNTL.U2OS 150 bp overlap

Motif DE_36h DE_36h-ATF2_MA1632.2 10 bp overlap

Motif DE_36h DE_36h-ATF7_MA0834.2 10 bp overlap

BRD4 3 datasets

ChIP SK-N-BE2-C_Naive-veh GSE107706.BRD4.SK-N-BE2-C_Naive-veh 138 bp overlap

ChIP SK-N-BE2-C_Resistant-veh GSE107706.BRD4.SK-N-BE2-C_Resistant-veh 179 bp overlap

ChIP SK-N-BE2-C_Resistant-veh GSE107706.BRD4.SK-N-BE2-C_Resistant-veh 453 bp overlap

ChIP G-401 GSE120234.BRD9.G-401 367 bp overlap

Motif DE_36h DE_36h-CDX4_MA1473.2 9 bp overlap

ChIP HeLa-S3 ENCSR000ECP.CHD2.HeLa-S3 132 bp overlap

ChIP retina_Hu20 GSE137311.CRX.retina_Hu20 260 bp overlap

ChIP retina_Hu21 GSE137311.CRX.retina_Hu21 284 bp overlap

ChIP retina_Hu3 GSE137311.CRX.retina_Hu3 284 bp overlap

ChIP retina_Hu6 GSE137311.CRX.retina_Hu6 341 bp overlap

ChIP retina_Hu6 GSE137311.CTCF.retina_Hu6 259 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF031ISE 102 bp overlap

ChIP BLaER1 ENCFF460KDD 166 bp overlap

Motif DE_36h DE_36h-Crx_MA0467.3 6 bp overlap

Motif DE_36h DE_36h-Crx_MA0467.3 6 bp overlap

ChIP HeLa-S3 ENCSR219MKK.DEK.HeLa-S3 51 bp overlap

DUX4 4 datasets

Motif DE_36h DE_36h-DUX4_MA0468.1 11 bp overlap

Motif DE_36h DE_36h-DUX4_MA0468.1 11 bp overlap

Motif DE_36h DE_36h-DUX4_MA0468.1 11 bp overlap

ChIP WA01 GSE94322.DUX4.WA01 277 bp overlap

Motif DE_36h DE_36h-DUXA_MA0884.2 13 bp overlap

Dmbx1 1 dataset

Motif DE_36h DE_36h-Dmbx1_MA0883.2 10 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 269 bp overlap

ETV5::HOXA2 1 dataset

Motif DE_36h DE_36h-ETV5HOXA2_MA1948.2 12 bp overlap

ChIP SU-DHL-5 GSE45982.EZH2.SU-DHL-5 63 bp overlap

Motif DE_36h DE_36h-FOS_MA1951.2 13 bp overlap

ChIP HeLa-S3 ENCSR000EZE.FOS.HeLa-S3 114 bp overlap

FOSB::JUN 1 dataset

Motif DE_36h DE_36h-FOSBJUN_MA1127.1 11 bp overlap

FOSB::JUNB 1 dataset

Motif DE_36h DE_36h-FOSBJUNB_MA1136.1 10 bp overlap

FOSL1::JUN 1 dataset

Motif DE_36h DE_36h-FOSL1JUN_MA1129.1 10 bp overlap

FOSL1::JUND 1 dataset

Motif DE_36h DE_36h-FOSL1JUND_MA1143.2 9 bp overlap

FOSL2::JUN 1 dataset

Motif DE_36h DE_36h-FOSL2JUN_MA1131.2 10 bp overlap

FOSL2::JUNB 1 dataset

Motif DE_36h DE_36h-FOSL2JUNB_MA1139.2 10 bp overlap

FOSL2::JUND 1 dataset

Motif DE_36h DE_36h-FOSL2JUND_MA1145.2 10 bp overlap

FOXA1 1 dataset

ChIP T-47D_JC4743 GSE126004.FOXA1.T-47D_JC4743 197 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 887 bp overlap

ChIP DE DE-FOXA2-2 541 bp overlap

FOXO1-PAX3 1 dataset

ChIP RH4_DMSO-6H GSE116344.FOXO1-PAX3.RH4_DMSO-6H 188 bp overlap

FOXP4 1 dataset

ChIP Hep-G2 ENCSR232LLP.FOXP4.Hep-G2 212 bp overlap

GATA2 1 dataset

ChIP Hep-G2 ENCSR897LDT.GATA2.Hep-G2 168 bp overlap

GATA3 2 datasets

ChIP MCF-7 GSE122847.GATA3.MCF-7 221 bp overlap

ChIP T-47D ENCSR000BMX.GATA3.T-47D 173 bp overlap

GATA3_Nter 1 dataset

ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 185 bp overlap

GATA4 4 datasets

ChIP DE DE-GATA4-1 593 bp overlap

ChIP DE DE-GATA4-2 710 bp overlap

ChIP foregut GSE117136.GATA4.foregut 296 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 363 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 693 bp overlap

ChIP DE DE-GATA6-2 603 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 546 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 441 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 657 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 363 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 497 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 561 bp overlap

ChIP foregut GSE117136.GATA6.foregut 265 bp overlap

GRHL2 1 dataset

ChIP LNCaP GSE80256.GRHL2.LNCaP 188 bp overlap

Motif DE_36h DE_36h-GSC_MA0648.2 6 bp overlap

Motif DE_36h DE_36h-GSC_MA0648.2 6 bp overlap

GSC2 2 datasets

Motif DE_36h DE_36h-GSC2_MA0891.2 6 bp overlap

Motif DE_36h DE_36h-GSC2_MA0891.2 6 bp overlap

HOXA10 1 dataset

Motif DE_36h DE_36h-HOXA10_MA0899.2 9 bp overlap

HOXB13 2 datasets

Motif DE_36h DE_36h-HOXB13_MA0901.3 9 bp overlap

ChIP G-401 GSE65381.HOXB13.G-401 715 bp overlap

HOXD9 1 dataset

Motif DE_36h DE_36h-HOXD9_MA0913.3 9 bp overlap

Hoxa13 1 dataset

Motif DE_36h DE_36h-Hoxa13_MA0650.4 8 bp overlap

Motif DE_36h DE_36h-JDP2_MA0656.2 10 bp overlap

Motif DE_36h DE_36h-JUN_MA0488.2 10 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 267 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 336 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 515 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 267 bp overlap

JUN::JUNB 1 dataset

Motif DE_36h DE_36h-JUNJUNB_MA1133.2 11 bp overlap

Motif DE_36h DE_36h-JUNB_MA1140.3 11 bp overlap

Motif DE_36h DE_36h-JUND_MA0492.2 11 bp overlap

KDM1A 1 dataset

ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 673 bp overlap

ChIP HEK293 ENCSR859BMR.KLF1.HEK293 201 bp overlap

ChIP HeLa-S3 ENCSR000EZF.MAX.HeLa-S3 402 bp overlap

MEF2D 2 datasets

ChIP retina_Hu13 GSE137311.MEF2D.retina_Hu13 304 bp overlap

ChIP retina_Hu25 GSE137311.MEF2D.retina_Hu25 222 bp overlap

Motif DE_36h DE_36h-MXI1_MA1108.3 6 bp overlap

ChIP HeLa-S3 ENCSR000EZD.MYC.HeLa-S3 284 bp overlap

ChIP RH4_Entinostat-6H GSE116344.MYOG.RH4_Entinostat-6H 206 bp overlap

Motif DE_36h DE_36h-MZF1_MA0056.3 8 bp overlap

NKX6-3 1 dataset

Motif DE_36h DE_36h-NKX6-3_MA1530.2 8 bp overlap

NR1D1 1 dataset

Motif DE_36h DE_36h-NR1D1_MA1531.2 14 bp overlap

NR1D2 1 dataset

Motif DE_36h DE_36h-NR1D2_MA1532.2 15 bp overlap

NR2C1 1 dataset

Motif DE_36h DE_36h-NR2C1_MA1535.2 6 bp overlap

NR2C2 1 dataset

Motif DE_36h DE_36h-NR2C2_MA1536.2 6 bp overlap

NR2F2 1 dataset

ChIP MCF-7 ENCSR000BUY.NR2F2.MCF-7 159 bp overlap

NR3C1 1 dataset

ChIP T47D-A1-2_Dex GSE112491.NR3C1.T47D-A1-2_Dex 91 bp overlap

Nr1H2 1 dataset

Motif DE_36h DE_36h-Nr1H2_MA1996.2 6 bp overlap

Nr1H4 1 dataset

Motif DE_36h DE_36h-Nr1H4_MA1110.3 6 bp overlap

Nr1h3 1 dataset

Motif DE_36h DE_36h-Nr1h3_MA2337.1 6 bp overlap

Nr2F6 1 dataset

Motif DE_36h DE_36h-Nr2F6_MA0728.1 15 bp overlap

ChIP HEK293 ENCSR324LTM.OSR2.HEK293 265 bp overlap

OTX1 2 datasets

Motif DE_36h DE_36h-OTX1_MA0711.2 6 bp overlap

Motif DE_36h DE_36h-OTX1_MA0711.2 6 bp overlap

OTX2 4 datasets

Motif DE_36h DE_36h-OTX2_MA0712.3 7 bp overlap

Motif DE_36h DE_36h-OTX2_MA0712.3 7 bp overlap

ChIP retina_Hu7 GSE137311.OTX2.retina_Hu7 416 bp overlap

ChIP retina_pigment GSE60024.OTX2.retina_pigment 230 bp overlap

PHOX2A 1 dataset

Motif DE_36h DE_36h-PHOX2A_MA0713.1 11 bp overlap

PHOX2B 1 dataset

Motif DE_36h DE_36h-PHOX2B_MA0681.3 12 bp overlap

PITX1 2 datasets

Motif DE_36h DE_36h-PITX1_MA0682.3 6 bp overlap

Motif DE_36h DE_36h-PITX1_MA0682.3 6 bp overlap

PITX2 2 datasets

Motif DE_36h DE_36h-PITX2_MA1547.2 8 bp overlap

Motif DE_36h DE_36h-PITX2_MA1547.2 8 bp overlap

PITX3 2 datasets

Motif DE_36h DE_36h-PITX3_MA0714.2 6 bp overlap

Motif DE_36h DE_36h-PITX3_MA0714.2 6 bp overlap

POU4F1 1 dataset

Motif DE_36h DE_36h-POU4F1_MA0790.2 12 bp overlap

POU4F3 1 dataset

Motif DE_36h DE_36h-POU4F3_MA0791.2 12 bp overlap

PROP1 1 dataset

Motif DE_36h DE_36h-PROP1_MA0715.1 11 bp overlap

Motif DE_36h DE_36h-RARA_MA0729.1 18 bp overlap

RARB 2 datasets

Motif DE_36h DE_36h-RARB_MA1552.2 13 bp overlap

Motif DE_36h DE_36h-RARB_MA1552.2 13 bp overlap

Motif DE_36h DE_36h-RARG_MA1553.2 13 bp overlap

RHOXF1 2 datasets

Motif DE_36h DE_36h-RHOXF1_MA0719.2 6 bp overlap

Motif DE_36h DE_36h-RHOXF1_MA0719.2 6 bp overlap

Motif DE_36h DE_36h-RORA_MA0072.2 11 bp overlap

ChIP retina_Hu22 GSE137311.RORB.retina_Hu22 367 bp overlap

Motif DE_36h DE_36h-Rarb_MA0857.1 16 bp overlap

Motif DE_36h DE_36h-Rarg_MA0859.2 15 bp overlap

SATB1 1 dataset

Motif DE_36h DE_36h-SATB1_MA1963.2 7 bp overlap

SCRT1 1 dataset

Motif DE_36h DE_36h-SCRT1_MA0743.3 10 bp overlap

SCRT2 1 dataset

Motif DE_36h DE_36h-SCRT2_MA0744.3 10 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 434 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 571 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 538 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 268 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 456 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 482 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 419 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 249 bp overlap

SMARCA4 4 datasets

ChIP BIN-67_lentivirus-SMARCA4-T910M GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4-T910M 149 bp overlap

ChIP G-401_Dox GSE71504.SMARCA4.G-401_Dox 251 bp overlap

ChIP G-401_NoDox GSE71504.SMARCA4.G-401_NoDox 227 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 293 bp overlap

SMARCB1 1 dataset

ChIP MCF-7_estrogen GSE123284.SMARCB1.MCF-7_estrogen 290 bp overlap

SMARCC1 2 datasets

ChIP G-401_Dox GSE71504.SMARCC1.G-401_Dox 284 bp overlap

ChIP G-401_NoDox GSE71504.SMARCC1.G-401_NoDox 302 bp overlap

SNAI2 1 dataset

ChIP SMS-CTR_D48 GSE137168.SNAI2.SMS-CTR_D48 256 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 594 bp overlap

Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap

Motif DE_36h DE_36h-SRF_MA0083.3 16 bp overlap

ZKSCAN5 1 dataset

Motif DE_36h DE_36h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF214 1 dataset

Motif DE_36h DE_36h-ZNF214_MA1975.2 13 bp overlap

ZNF264 2 datasets

ChIP HEK293 GSE76494.ZNF264.HEK293 151 bp overlap

ChIP Hep-G2 ENCSR248BVU.ZNF264.Hep-G2 180 bp overlap

ZNF528 1 dataset

ChIP HEK293 GSE76494.ZNF528.HEK293 289 bp overlap

ZNF549 1 dataset

Motif DE_36h DE_36h-ZNF549_MA1728.2 8 bp overlap

ZNF770 2 datasets

ChIP HEK293 ENCFF468FCG 258 bp overlap

ChIP HEK293 ENCSR242BGR.ZNF770.HEK293 215 bp overlap