Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

56 transcription factors

ARNTL 1 dataset

ChIP U2OS_trough_DMOG GSE85096.ARNTL.U2OS_trough_DMOG 229 bp overlap

ASCL1 4 datasets

ChIP NCI-H889 GSE69394.ASCL1.NCI-H889 129 bp overlap

ChIP NCI-H889 GSE69394.ASCL1.NCI-H889 131 bp overlap

ChIP SCLC_ASCLP GSE61197.ASCL1.SCLC_ASCLP 149 bp overlap

ChIP SCLC_ASCLP_NE GSE61197.ASCL1.SCLC_ASCLP_NE 192 bp overlap

BRD4 2 datasets

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 156 bp overlap

ChIP RH4_shscr GSE140115.BRD4.RH4_shscr 132 bp overlap

CHD4 1 dataset

ChIP SCMC GSE155861.CHD4.SCMC 276 bp overlap

CTCF 2 datasets

ChIP NB69 GSE101295.CTCF.NB69 116 bp overlap

ChIP RH4 GSE83726.CTCF.RH4 205 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF093OYK 162 bp overlap

ChIP BLaER1 ENCFF364PUR 256 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 173 bp overlap

EP300 1 dataset

ChIP SK-N-SH ENCSR000EHV.EP300.SK-N-SH 103 bp overlap

EZH2 1 dataset

ChIP RH30_DMSO GSE85169.EZH2.RH30_DMSO 484 bp overlap

FOXJ3 1 dataset

ChIP SK-N-SH ENCFF124KVL 120 bp overlap

GATA6 2 datasets

ChIP DE_D1 S41-DE-d1-GATA6-exp2 344 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 265 bp overlap

HAND2 3 datasets

ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 252 bp overlap

ChIP Kelly GSE94822.HAND2.Kelly 271 bp overlap

ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 284 bp overlap

HDAC2 2 datasets

ChIP RH4_DMSO-6H GSE116344.HDAC2.RH4_DMSO-6H 86 bp overlap

ChIP RH4_Entinostat-6H GSE116344.HDAC2.RH4_Entinostat-6H 174 bp overlap

HDAC3 1 dataset

ChIP RH4_DMSO-6H GSE116344.HDAC3.RH4_DMSO-6H 120 bp overlap

HIF1A 1 dataset

ChIP U2OS_trough_DMOG GSE85096.HIF1A.U2OS_trough_DMOG 274 bp overlap

HNF1B 1 dataset

ChIP foregut GSE117136.HNF1B.foregut 365 bp overlap

ISL1 1 dataset

ChIP SK-N-BE2-C GSE94822.ISL1.SK-N-BE2-C 140 bp overlap

JUN 1 dataset

ChIP HAEC_TNFa_4h GSE89970.JUN.HAEC_TNFa_4h 134 bp overlap

KDM1A 2 datasets

ChIP SH-SY5Y_B3 GSE58258.KDM1A.SH-SY5Y_B3 216 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.KDM1A.pancreatic-progenitor_PP1 358 bp overlap

MAX 3 datasets

ChIP H1 ENCFF914VQY 293 bp overlap

ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 484 bp overlap

ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 484 bp overlap

MTA2 1 dataset

ChIP RH4 GSE155861.MTA2.RH4 61 bp overlap

MXI1 2 datasets

ChIP SK-N-SH ENCFF746HVJ 347 bp overlap

ChIP SK-N-SH ENCSR000EIA.MXI1.SK-N-SH 225 bp overlap

MYC 2 datasets

ChIP NCI-H128 GSE41105.MYC.NCI-H128 195 bp overlap

ChIP NCI-H2171 GSE36354.MYC.NCI-H2171 331 bp overlap

MYCN 5 datasets

ChIP COG-N-415 GSE138295.MYCN.COG-N-415 257 bp overlap

ChIP Kelly GSE94822.MYCN.Kelly 193 bp overlap

ChIP Kelly_sensitive GSE115249.MYCN.Kelly_sensitive 233 bp overlap

ChIP RH4 GSE83726.MYCN.RH4 335 bp overlap

ChIP SK-N-BE2-C GSE94822.MYCN.SK-N-BE2-C 214 bp overlap

MYOD1 5 datasets

ChIP RD GSE137168.MYOD1.RD 129 bp overlap

ChIP RD_shSNAI2 GSE137168.MYOD1.RD_shSNAI2 128 bp overlap

ChIP RH30_DMSO GSE85169.MYOD1.RH30_DMSO 484 bp overlap

ChIP RH4 GSE83726.MYOD1.RH4 381 bp overlap

ChIP rhabdomyosarcoma GSE50413.MYOD1.rhabdomyosarcoma 215 bp overlap

NEUROD1 1 dataset

ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 269 bp overlap

NEUROG2 2 datasets

ChIP MRC-5_NFD_02DPT GSE75910.NEUROG2.MRC-5_NFD_02DPT 293 bp overlap

ChIP MRC-5_NFD_1DPT GSE75910.NEUROG2.MRC-5_NFD_1DPT 239 bp overlap

NKX3-1 1 dataset

ChIP islet ERP004003.NKX3-1.islet 225 bp overlap

PDX1 5 datasets

ChIP hESC GSE58685.PDX1.hESC 179 bp overlap

ChIP hiPSC GSE125768.PDX1.hiPSC 336 bp overlap

ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 383 bp overlap

ChIP islet ERP001456.PDX1.islet 140 bp overlap

ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 377 bp overlap

PGR 1 dataset

ChIP T-47D_R5020-A1 GSE126859.PGR.T-47D_R5020-A1 229 bp overlap

PHOX2B 1 dataset

ChIP CLB-Ga GSE90683.PHOX2B.CLB-Ga 183 bp overlap

PITX3 1 dataset

ChIP SH-SY5Y GSE93275.PITX3.SH-SY5Y 236 bp overlap

POLR2A 1 dataset

ChIP gastrocnemius medialis ENCFF145VIB 484 bp overlap

POU5F1 1 dataset

ChIP HUES-8 GSE109524.POU5F1.HUES-8 279 bp overlap

RAD21 1 dataset

ChIP RH4 GSE83726.RAD21.RH4 217 bp overlap

RBBP4 2 datasets

ChIP RH5 GSE155861.RBBP4.RH5 210 bp overlap

ChIP SCMC GSE155861.RBBP4.SCMC 60 bp overlap

RCOR1 1 dataset

ChIP SK-N-SH ENCSR009TKN.RCOR1.SK-N-SH 73 bp overlap

RELA 1 dataset

ChIP aortic-endothelial-cell_IL1B_D7 GSE139377.RELA.aortic-endothelial-cell_IL1B_D7 146 bp overlap

RXR 1 dataset

ChIP pancreatic-progenitor_PP1 GSE104840.RXR.pancreatic-progenitor_PP1 163 bp overlap

SAP30 1 dataset

ChIP WA01 ENCSR000ATR.SAP30.WA01 180 bp overlap

SIN3A 2 datasets

ChIP WA01 ENCSR000BIS.SIN3A.WA01 109 bp overlap

ChIP WA01 ENCSR000EBO.SIN3A.WA01 384 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 246 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 484 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 321 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 336 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 311 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 185 bp overlap

SMAD3 1 dataset

ChIP endoderm GSE29422.SMAD3.endoderm 173 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 169 bp overlap

SMARCA4 1 dataset

ChIP 501-mel_SHSOX10 GSE61965.SMARCA4.501-mel_SHSOX10 207 bp overlap

TBX2 1 dataset

ChIP SK-N-BE2-C GSE94822.TBX2.SK-N-BE2-C 85 bp overlap

TCF3 2 datasets

ChIP Kasumi-1 GSE43834.TCF3.Kasumi-1 174 bp overlap

ChIP NPC GSE154479.TCF3.NPC 241 bp overlap

TCF4 1 dataset

ChIP SH-SY5Y GSE96915.TCF4.SH-SY5Y 214 bp overlap

TP63 1 dataset

ChIP keratinocyte_D7 GSE59824.TP63.keratinocyte_D7 130 bp overlap

TWIST1 2 datasets

ChIP BE2C GSE80151.TWIST1.BE2C 307 bp overlap

ChIP SK-N-BE2-C GSE80151.TWIST1.SK-N-BE2-C 307 bp overlap

USF1 1 dataset

ChIP SK-N-SH ENCSR000BMF.USF1.SK-N-SH 159 bp overlap

ZEB1 1 dataset

ChIP neuron_bipolar_doxy_4d ENCSR418KUS.ZEB1.neuron_bipolar_doxy_4d 121 bp overlap

ZNF19 1 dataset

ChIP HEK293T GSE78099.ZNF19.HEK293T 160 bp overlap

ZNF652 1 dataset

ChIP Hep-G2 ENCSR502GAX.ZNF652.Hep-G2 166 bp overlap

Gene	Dist. to TSS	Distance	Link type
TGFB3	8.9 kb	Proximal	Proximity
IFT43	13.0 kb	Distal	Multiome
GPATCH2L	179.2 kb	Distal	Multiome
TTLL5	311.8 kb	Distal	Multiome+HiCAR
ERG28	311.9 kb	Distal	Multiome+HiCAR
FLVCR2	394.2 kb	Distal	Multiome+HiCAR

Genome Browser