chr14 : 94,776,794 – 94,777,527

733 bp 56 TFs 2 linked genes

This 733 bp open chromatin element is linked to ENSG00000285205 and GSC and is bound by 56 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000285205		6.5 kb	Proximal	Proximity
GSC		6.7 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

56 transcription factors

Atf3 1 dataset

Motif DE_72h DE_72h-Atf3_MA1988.2 7 bp overlap

BACH1 1 dataset

Motif DE_72h DE_72h-BACH1_MA1633.2 9 bp overlap

BATF 1 dataset

Motif DE_72h DE_72h-BATF_MA1634.2 7 bp overlap

BATF3 1 dataset

Motif DE_72h DE_72h-BATF3_MA0835.3 7 bp overlap

BATF::JUN 1 dataset

Motif DE_72h DE_72h-BATFJUN_MA0462.3 7 bp overlap

BCL11A 1 dataset

Motif DE_72h DE_72h-BCL11A_MA2324.1 7 bp overlap

BNC2 1 dataset

Motif DE_72h DE_72h-BNC2_MA1928.2 7 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 196 bp overlap

ESR1 5 datasets

ChIP U2OS_100nM-E2 GSE151039.ESR1.U2OS_100nM-E2 305 bp overlap

ChIP U2OS_10nM-E2 GSE151039.ESR1.U2OS_10nM-E2 461 bp overlap

ChIP U2OS_10nM-E2-B GSE151039.ESR1.U2OS_10nM-E2-B 339 bp overlap

ChIP breast_tumor_Male_26 GSE104399.ESR1.breast_tumor_Male_26 260 bp overlap

ChIP endometrioid-adenocarcinoma_tumor_2 GSE94031.ESR1.endometrioid-adenocarcinoma_tumor_2 244 bp overlap

EZH2 5 datasets

ChIP A-1847 GSE95643.EZH2.A-1847 254 bp overlap

ChIP A-1847 GSE95643.EZH2.A-1847 382 bp overlap

ChIP GM23338 ENCSR045YHA.EZH2.GM23338 238 bp overlap

ChIP THP-1 GSE135024.EZH2.THP-1 213 bp overlap

ChIP WA01 ENCSR000ASY.EZH2.WA01 340 bp overlap

FOS 1 dataset

Motif DE_72h DE_72h-FOS_MA0476.2 8 bp overlap

FOS::JUN 1 dataset

Motif DE_72h DE_72h-FOSJUN_MA0099.4 9 bp overlap

FOS::JUNB 1 dataset

Motif DE_72h DE_72h-FOSJUNB_MA1134.2 9 bp overlap

FOS::JUND 1 dataset

Motif DE_72h DE_72h-FOSJUND_MA1141.2 9 bp overlap

FOSB::JUNB 1 dataset

Motif DE_72h DE_72h-FOSBJUNB_MA1135.2 9 bp overlap

FOSL1 1 dataset

Motif DE_72h DE_72h-FOSL1_MA0477.3 9 bp overlap

FOSL1::JUN 1 dataset

Motif DE_72h DE_72h-FOSL1JUN_MA1128.2 9 bp overlap

FOSL1::JUNB 1 dataset

Motif DE_72h DE_72h-FOSL1JUNB_MA1137.2 9 bp overlap

FOSL1::JUND 2 datasets

Motif DE_72h DE_72h-FOSL1JUND_MA1142.2 8 bp overlap

Motif DE_72h DE_72h-FOSL1JUND_MA1143.2 9 bp overlap

FOSL2::JUN 1 dataset

Motif DE_72h DE_72h-FOSL2JUN_MA1130.2 9 bp overlap

FOSL2::JUNB 1 dataset

Motif DE_72h DE_72h-FOSL2JUNB_MA1138.2 9 bp overlap

FOSL2::JUND 1 dataset

Motif DE_72h DE_72h-FOSL2JUND_MA1144.2 9 bp overlap

FOXA1 2 datasets

ChIP NCI-H3122 GSE39998.FOXA1.NCI-H3122 280 bp overlap

ChIP NCI-H3122 GSE39998.FOXA1.NCI-H3122 245 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 733 bp overlap

ChIP DE DE-FOXA2-2 733 bp overlap

FOXE1 1 dataset

Motif DE_72h DE_72h-FOXE1_MA1487.3 12 bp overlap

Foxl2 1 dataset

Motif DE_72h DE_72h-Foxl2_MA1607.2 10 bp overlap

Foxq1 1 dataset

Motif DE_72h DE_72h-Foxq1_MA0040.2 10 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 732 bp overlap

ChIP DE DE-GATA4-2 724 bp overlap

GATA6 4 datasets

ChIP DE DE-GATA6-1 690 bp overlap

ChIP DE DE-GATA6-2 720 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 391 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 300 bp overlap

JDP2 1 dataset

Motif DE_72h DE_72h-JDP2_MA0655.1 9 bp overlap

JUN 3 datasets

ChIP DE_D1 S40-DE-d1-JUN-exp2 595 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 499 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 471 bp overlap

JUN::JUNB 1 dataset

Motif DE_72h DE_72h-JUNJUNB_MA1132.2 8 bp overlap

JUNB 1 dataset

Motif DE_72h DE_72h-JUNB_MA0490.3 9 bp overlap

JUND 1 dataset

Motif DE_72h DE_72h-JUND_MA0491.3 9 bp overlap

Jun 1 dataset

Motif DE_72h DE_72h-Jun_MA0489.3 8 bp overlap

NFE2 1 dataset

Motif DE_72h DE_72h-NFE2_MA0841.2 10 bp overlap

NKX2-1 1 dataset

ChIP NCI-H3122 GSE39998.NKX2-1.NCI-H3122 718 bp overlap

POU5F1 1 dataset

ChIP BJ_INDUCED GSE36570.POU5F1.BJ_INDUCED 74 bp overlap

PSIP1 1 dataset

ChIP T-REx-293 GSE117155.PSIP1.T-REx-293 192 bp overlap

RNF2 1 dataset

ChIP WA09 GSE105028.RNF2.WA09 518 bp overlap

RORB 1 dataset

Motif DE_72h DE_72h-RORB_MA1150.2 10 bp overlap

Rarb 1 dataset

Motif DE_72h DE_72h-Rarb_MA0857.1 16 bp overlap

Rarg 1 dataset

Motif DE_72h DE_72h-Rarg_MA0859.2 15 bp overlap

SCRT2 1 dataset

ChIP HEK293 ENCFF711QQB 367 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 134 bp overlap

SMAD2-3 4 datasets

ChIP HGrC1_WT-TGF GSE138496.SMAD2-3.HGrC1_WT-TGF 125 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 733 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 347 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 440 bp overlap

SMAD2_3 4 datasets

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 327 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 481 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 733 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 733 bp overlap

SMARCC1 1 dataset

ChIP DE_D1 S15-DE-d1-BAF155-exp1 243 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 307 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 715 bp overlap

SREBF2 1 dataset

Motif DE_72h DE_72h-SREBF2_MA0596.1 10 bp overlap

STAT3 3 datasets

ChIP T-47D_JC4757 GSE126004.STAT3.T-47D_JC4757 263 bp overlap

ChIP T-47D_JC5054 GSE126004.STAT3.T-47D_JC5054 281 bp overlap

ChIP T-47D_JC5062 GSE126004.STAT3.T-47D_JC5062 264 bp overlap

T 1 dataset

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 179 bp overlap

TOP2A 1 dataset

ChIP KG-1_etoposide_VP16 GSE114048.TOP2A.KG-1_etoposide_VP16 81 bp overlap

ZNF341 1 dataset

Motif DE_72h DE_72h-ZNF341_MA1655.2 8 bp overlap

ZSCAN4 2 datasets

ChIP HEK293 ENCFF381BKT 310 bp overlap

ChIP HEK293 ENCSR211GNP.ZSCAN4.HEK293 204 bp overlap