chr15 : 58,561,174 – 58,561,683
509 bp 27 TFs 2 linked genes
This 509 bp open chromatin element is linked to ADAM10 and MINDY2 and is bound by 27 transcription factors.
Linked Genes
2 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ADAM10 188.3 kb Distal Multiome
MINDY2 209.7 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr15:58,556,174 – 58,566,683
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
27 transcription factors
Source
Cell type
AR 1 dataset
ChIP MCF-7 ERP001226.AR.MCF-7 103 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 302 bp overlap
ESR1 64 datasets
ChIP MCF-7 GSE148277.ESR1.MCF-7 214 bp overlap
ChIP MCF-7 GSE76893.ESR1.MCF-7 173 bp overlap
ChIP MCF-7 GSE95302.ESR1.MCF-7 139 bp overlap
ChIP MCF-7 GSE48930.ESR1.MCF-7 105 bp overlap
ChIP MCF-7 GSE103023.ESR1.MCF-7 134 bp overlap
ChIP MCF-7 GSE41561.ESR1.MCF-7 105 bp overlap
ChIP MCF-7 GSE68355.ESR1.MCF-7 215 bp overlap
ChIP MCF-7 GSE45822.ESR1.MCF-7 126 bp overlap
ChIP MCF-7-Luc-Y537S_E2 GSE78284.ESR1.MCF-7-Luc-Y537S_E2 54 bp overlap
ChIP MCF-7-Luc_E2 GSE78284.ESR1.MCF-7-Luc_E2 171 bp overlap
ChIP MCF-7_ARID1A-KO GSE123284.ESR1.MCF-7_ARID1A-KO 145 bp overlap
ChIP MCF-7_ARID1A-KO_4-OHT GSE123284.ESR1.MCF-7_ARID1A-KO_4-OHT 130 bp overlap
ChIP MCF-7_ARID1A-KO_4-OHT_clone14 GSE123284.ESR1.MCF-7_ARID1A-KO_4-OHT_clone14 155 bp overlap
ChIP MCF-7_ARID1A-KO_clone14 GSE123284.ESR1.MCF-7_ARID1A-KO_clone14 127 bp overlap
ChIP MCF-7_AZD2014 GSE103023.ESR1.MCF-7_AZD2014 96 bp overlap
ChIP MCF-7_D538G GSE148277.ESR1.MCF-7_D538G 162 bp overlap
ChIP MCF-7_D538G_DMSO GSE148277.ESR1.MCF-7_D538G_DMSO 176 bp overlap
ChIP MCF-7_DMSO GSE125594.ESR1.MCF-7_DMSO 198 bp overlap
ChIP MCF-7_DMSO GSE148277.ESR1.MCF-7_DMSO 158 bp overlap
ChIP MCF-7_E2 GSE59530.ESR1.MCF-7_E2 156 bp overlap
ChIP MCF-7_E2 ERP000209.ESR1.MCF-7_E2 135 bp overlap
ChIP MCF-7_E2 GSE60270.ESR1.MCF-7_E2 151 bp overlap
ChIP MCF-7_E2 ERP000380.ESR1.MCF-7_E2 61 bp overlap
ChIP MCF-7_E2 ERP000901.ESR1.MCF-7_E2 86 bp overlap
ChIP MCF-7_E2 GSE14664.ESR1.MCF-7_E2 180 bp overlap
ChIP MCF-7_E2 GSE117941.ESR1.MCF-7_E2 170 bp overlap
ChIP MCF-7_E2-10min-ERalpha GSE94023.ESR1.MCF-7_E2-10min-ERalpha 147 bp overlap
ChIP MCF-7_E2-1280-min-ERalpha GSE94023.ESR1.MCF-7_E2-1280-min-ERalpha 169 bp overlap
ChIP MCF-7_E2-160min-ERalpha GSE94023.ESR1.MCF-7_E2-160min-ERalpha 119 bp overlap
ChIP MCF-7_E2-20min-ERalpha GSE94023.ESR1.MCF-7_E2-20min-ERalpha 181 bp overlap
ChIP MCF-7_E2-320min-ERalpha GSE94023.ESR1.MCF-7_E2-320min-ERalpha 60 bp overlap
ChIP MCF-7_E2-40min-ERalpha GSE94023.ESR1.MCF-7_E2-40min-ERalpha 144 bp overlap
ChIP MCF-7_E2-5min-ERalpha GSE94023.ESR1.MCF-7_E2-5min-ERalpha 134 bp overlap
ChIP MCF-7_E2-80min-ERalpha GSE94023.ESR1.MCF-7_E2-80min-ERalpha 157 bp overlap
ChIP MCF-7_E2PG GSE68356.ESR1.MCF-7_E2PG 109 bp overlap
ChIP MCF-7_E2_30min GSE108883.ESR1.MCF-7_E2_30min 171 bp overlap
ChIP MCF-7_E2_45m GSE67295.ESR1.MCF-7_E2_45m 152 bp overlap
ChIP MCF-7_E2_45min GSE109820.ESR1.MCF-7_E2_45min 148 bp overlap
ChIP MCF-7_E2_90min GSE109820.ESR1.MCF-7_E2_90min 157 bp overlap
ChIP MCF-7_E2_talen GSE94493.ESR1.MCF-7_E2_talen 84 bp overlap
ChIP MCF-7_GLYC ERP002305.ESR1.MCF-7_GLYC 105 bp overlap
ChIP MCF-7_HC11 GSE102882.ESR1.MCF-7_HC11 180 bp overlap
ChIP MCF-7_PROG GSE68355.ESR1.MCF-7_PROG 163 bp overlap
ChIP MCF-7_R5020 GSE68355.ESR1.MCF-7_R5020 151 bp overlap
ChIP MCF-7_RAD001 GSE103023.ESR1.MCF-7_RAD001 136 bp overlap
ChIP MCF-7_SHCRT_E2 ERP000380.ESR1.MCF-7_SHCRT_E2 146 bp overlap
ChIP MCF-7_SHFOXA1_E2 ERP000380.ESR1.MCF-7_SHFOXA1_E2 102 bp overlap
ChIP MCF-7_SICTR_E2 GSE40129.ESR1.MCF-7_SICTR_E2 113 bp overlap
ChIP MCF-7_SIGATA_E2 GSE40129.ESR1.MCF-7_SIGATA_E2 116 bp overlap
ChIP MCF-7_estradiol-DHT_4h GSE99626.ESR1.MCF-7_estradiol-DHT_4h 80 bp overlap
ChIP MCF-7_estradiol-Dex_4h GSE99626.ESR1.MCF-7_estradiol-Dex_4h 63 bp overlap
ChIP MCF-7_estradiol-aldosterone_4h GSE99626.ESR1.MCF-7_estradiol-aldosterone_4h 162 bp overlap
ChIP MCF-7_estradiol-progesterone_4h GSE99626.ESR1.MCF-7_estradiol-progesterone_4h 182 bp overlap
ChIP MCF-7_estradiol_4h GSE99626.ESR1.MCF-7_estradiol_4h 172 bp overlap
ChIP MCF-7_jc5849 GSE126004.ESR1.MCF-7_jc5849 163 bp overlap
ChIP MCF-7_jc5850 GSE126004.ESR1.MCF-7_jc5850 161 bp overlap
ChIP MCF-7_jc5852 GSE126004.ESR1.MCF-7_jc5852 167 bp overlap
ChIP MCF-7_jc5855 GSE126004.ESR1.MCF-7_jc5855 155 bp overlap
ChIP MCF-7_parental GSE123284.ESR1.MCF-7_parental 183 bp overlap
ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.ESR1.MCF-7_parental_4-hydroxytamoxifen 201 bp overlap
ChIP MCF-7_shTEAD4 GSE125594.ESR1.MCF-7_shTEAD4 181 bp overlap
ChIP MDA-MB-134-VI_E2 GSE109103.ESR1.MDA-MB-134-VI_E2 179 bp overlap
ChIP T-47D GSE148277.ESR1.T-47D 185 bp overlap
ChIP pleural-effusion GSE86538.ESR1.pleural-effusion 146 bp overlap
ESR1_D538G 2 datasets
ChIP MCF-7_dox GSE94493.ESR1_D538G.MCF-7_dox 168 bp overlap
ChIP MCF-7_dox_E2 GSE94493.ESR1_D538G.MCF-7_dox_E2 143 bp overlap
ESR1_Y537N 3 datasets
ChIP MCF-7_E2 GSE94493.ESR1_Y537N.MCF-7_E2 55 bp overlap
ChIP MCF-7_dox GSE94493.ESR1_Y537N.MCF-7_dox 201 bp overlap
ChIP MCF-7_dox_E2 GSE94493.ESR1_Y537N.MCF-7_dox_E2 120 bp overlap
ESR1_Y537S 5 datasets
ChIP MCF-7_E2 GSE94493.ESR1_Y537S.MCF-7_E2 194 bp overlap
ChIP MCF-7_dox GSE94493.ESR1_Y537S.MCF-7_dox 187 bp overlap
ChIP T-47D_E2 GSE94493.ESR1_Y537S.T-47D_E2 50 bp overlap
ChIP T-47D_dox GSE94493.ESR1_Y537S.T-47D_dox 154 bp overlap
ChIP T-47D_dox_E2 GSE94493.ESR1_Y537S.T-47D_dox_E2 143 bp overlap
ESR1_pS118 2 datasets
ChIP MCF-7_E2_ab GSE117569.ESR1_pS118.MCF-7_E2_ab 140 bp overlap
ChIP MCF-7_E2_sc GSE117569.ESR1_pS118.MCF-7_E2_sc 222 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 509 bp overlap
ChIP DE DE-FOXA2-2 509 bp overlap
GATA4 4 datasets
ChIP DE DE-GATA4-1 509 bp overlap
ChIP DE DE-GATA4-2 509 bp overlap
ChIP foregut GSE117136.GATA4.foregut 417 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 252 bp overlap
GATA6 11 datasets
ChIP DE DE-GATA6-1 438 bp overlap
ChIP DE DE-GATA6-2 509 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 509 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 509 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 509 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 455 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 509 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 494 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 435 bp overlap
ChIP foregut GSE117136.GATA6.foregut 300 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 414 bp overlap
JUN 1 dataset
ChIP DE_D2 S02-DE-d2-JUN-exp1 429 bp overlap
MEIS2 1 dataset
ChIP K-562 ENCSR851BNE.MEIS2.K-562 120 bp overlap
NANOG 1 dataset
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 466 bp overlap
NCOA2 1 dataset
ChIP MCF-7_E2 ERP000901.NCOA2.MCF-7_E2 118 bp overlap
NCOA3 1 dataset
ChIP MCF-7_E2 ERP000901.NCOA3.MCF-7_E2 95 bp overlap
NRIP1 1 dataset
ChIP MCF-7_E2 ERP005838.NRIP1.MCF-7_E2 81 bp overlap
PKNOX1 4 datasets
ChIP K-562 ENCSR115SMW.PKNOX1.K-562 114 bp overlap
ChIP K562 ENCFF236IUS 178 bp overlap
ChIP MCF-7 ENCFF116OCS 137 bp overlap
ChIP MCF-7 ENCSR986XYK.PKNOX1.MCF-7 101 bp overlap
POU5F1 1 dataset
ChIP DE_D1 DED1-OCT4_Batch_II 376 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 377 bp overlap
RELA 1 dataset
ChIP MCF-7_Veh GSE67295.RELA.MCF-7_Veh 105 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 509 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 509 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 509 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 509 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 509 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 454 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 509 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 509 bp overlap
SMARCA4 1 dataset
ChIP hiPSC GSE124903.SMARCA4.hiPSC 265 bp overlap
SMARCB1 1 dataset
ChIP hiPSC GSE124903.SMARCB1.hiPSC 268 bp overlap
SMARCC1 1 dataset
ChIP DE_D1 S15-DE-d1-BAF155-exp1 384 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 311 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 386 bp overlap
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