chr16 : 2,954,158 – 2,954,471

313 bp 49 TFs 2 linked genes

This 313 bp open chromatin element is linked to ENSG00000262482 and KREMEN2 and is bound by 49 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000262482		at TSS	At TSS	Proximity
KREMEN2		9.8 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

49 transcription factors

AR 1 dataset

ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 99 bp overlap

ASCL1 1 dataset

ChIP NCI-H82 GSE69394.ASCL1.NCI-H82 156 bp overlap

BCL6 1 dataset

ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 313 bp overlap

BORCS8-MEF2B,MEF2B 2 datasets

ChIP GM12878 ENCFF427QAI 81 bp overlap

ChIP GM12878 ENCFF427QAI 285 bp overlap

BRD1 1 dataset

ChIP HUES-64 GSE104059.BRD1.HUES-64 233 bp overlap

BRD4 1 dataset

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 134 bp overlap

CDK9 1 dataset

ChIP MM1-S_DMSO GSE42161.CDK9.MM1-S_DMSO 218 bp overlap

CTCF 1 dataset

ChIP T-47D_Y537S GSE148277.CTCF.T-47D_Y537S 196 bp overlap

E2F6 6 datasets

ChIP H1 ENCFF785DWK 194 bp overlap

ChIP K-562 ENCSR000EWJ.E2F6.K-562 145 bp overlap

ChIP K-562 ENCSR000BLI.E2F6.K-562 238 bp overlap

ChIP K562 ENCFF136LTS 296 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 181 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 78 bp overlap

EBF1 1 dataset

ChIP NALM-6 GSE126300.EBF1.NALM-6 313 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 185 bp overlap

EZH2 2 datasets

ChIP GM23248 ENCSR131FFJ.EZH2.GM23248 267 bp overlap

ChIP astrocyte ENCSR000ARR.EZH2.astrocyte 251 bp overlap

GATA6 6 datasets

ChIP DE DE-GATA6-2 238 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 313 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 313 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 313 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 313 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 313 bp overlap

HDAC2 1 dataset

ChIP WA01 ENCSR000AVB.HDAC2.WA01 58 bp overlap

JUN 3 datasets

ChIP DE_D1 S40-DE-d1-JUN-exp2 227 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 243 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 280 bp overlap

KDM4A 1 dataset

ChIP WA01 ENCSR000AVC.KDM4A.WA01 129 bp overlap

KMT2A 1 dataset

ChIP RCH-ACV GSE83671.KMT2A.RCH-ACV 249 bp overlap

L3MBTL2 1 dataset

ChIP K-562 ENCSR530XQI.L3MBTL2.K-562 223 bp overlap

MAX 1 dataset

ChIP K562 ENCFF524IJO 313 bp overlap

MED1 1 dataset

ChIP MM1-S_JQ1_50NM GSE49224.MED1.MM1-S_JQ1_50NM 105 bp overlap

MITF 1 dataset

ChIP 501-mel GSE137522.MITF.501-mel 95 bp overlap

MYC 1 dataset

ChIP NCI-H128 GSE41105.MYC.NCI-H128 313 bp overlap

MYCN 1 dataset

ChIP CHP-134 GSE129588.MYCN.CHP-134 173 bp overlap

NEUROD1 1 dataset

ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 225 bp overlap

NEUROG2 3 datasets

ChIP MRC-5_NFD_02DPT GSE75910.NEUROG2.MRC-5_NFD_02DPT 176 bp overlap

ChIP MRC-5_NFD_05DPT GSE75910.NEUROG2.MRC-5_NFD_05DPT 253 bp overlap

ChIP MRC-5_NFD_1DPT GSE75910.NEUROG2.MRC-5_NFD_1DPT 240 bp overlap

NOTCH1 1 dataset

ChIP HPBALL GSE39263.NOTCH1.HPBALL 152 bp overlap

PAX5 3 datasets

ChIP GM12878 ENCSR000BHJ.PAX5.GM12878 86 bp overlap

ChIP NALM-6 GSE126300.PAX5.NALM-6 313 bp overlap

ChIP NALM-6 GSE115764.PAX5.NALM-6 143 bp overlap

PBX1 1 dataset

ChIP RCH-ACV GSE85988.PBX1.RCH-ACV 55 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 313 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 313 bp overlap

RBBP4 1 dataset

ChIP RH5 GSE155861.RBBP4.RH5 127 bp overlap

RUNX1 1 dataset

ChIP NALM-6 GSE126300.RUNX1.NALM-6 158 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 313 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 313 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 313 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 313 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 313 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 313 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 313 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 313 bp overlap

SMAD3 1 dataset

ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 172 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 139 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 313 bp overlap

SRSF1 1 dataset

ChIP Hep-G2 GSE120104.SRSF1.Hep-G2 88 bp overlap

SUZ12 2 datasets

ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 235 bp overlap

ChIP CRL-7250_shSS18-SSX GSE108025.SUZ12.CRL-7250_shSS18-SSX 313 bp overlap

TARDBP 2 datasets

ChIP K-562 ENCSR429XTR.TARDBP.K-562 247 bp overlap

ChIP K-562 GSE120104.TARDBP.K-562 201 bp overlap

TCF3 1 dataset

ChIP 697_HF GSE138031.TCF3.697_HF 130 bp overlap

TCF4 1 dataset

ChIP CAL-1 GSE76147.TCF4.CAL-1 142 bp overlap

USF1 2 datasets

ChIP H1 ENCFF090WVU 129 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 88 bp overlap

ZBTB48 1 dataset

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 313 bp overlap

ZEB1 1 dataset

ChIP neuron_bipolar_doxy_4d ENCSR418KUS.ZEB1.neuron_bipolar_doxy_4d 205 bp overlap

ZFX 1 dataset

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 108 bp overlap

ZNF263 1 dataset

ChIP K-562 ENCSR000EWN.ZNF263.K-562 225 bp overlap

ZNF3 1 dataset

ChIP K-562 ENCSR195QFV.ZNF3.K-562 204 bp overlap

ZNF600 1 dataset

ChIP HEK293 ENCFF785JSX 239 bp overlap