chr16 : 65,318,705 – 65,319,215
510 bp 118 TFs 3 linked genes
This 510 bp open chromatin element is linked to ENSG00000260834, ENSG00000260364, and CDH11 and is bound by 118 transcription factors.
Linked Genes
3 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000260834 84.0 kb Distal Multiome
ENSG00000260364 85.9 kb Distal Multiome
CDH11 196.6 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr16:65,313,705 – 65,324,215
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
118 transcription factors
Source
Cell type
ATF2 1 dataset
ChIP WA01 ENCSR000BQU.ATF2.WA01 146 bp overlap
ATRX 1 dataset
ChIP metastatic-neuroblastoma_CHLA90 GSE100148.ATRX.metastatic-neuroblastoma_CHLA90 229 bp overlap
Arid3a 1 dataset
Motif DE_12h DE_12h-Arid3a_MA0151.1 6 bp overlap
BCL11B 1 dataset
ChIP thymus_CD34neg GSE84677.BCL11B.thymus_CD34neg 143 bp overlap
BCOR 1 dataset
ChIP WA01 GSE104690.BCOR.WA01 159 bp overlap
BRD4 3 datasets
ChIP SK-N-BE2-C_Naive-veh GSE107706.BRD4.SK-N-BE2-C_Naive-veh 109 bp overlap
ChIP SK-N-BE2-C_Naive-veh GSE107706.BRD4.SK-N-BE2-C_Naive-veh 204 bp overlap
ChIP SK-N-BE2-C_Resistant-veh GSE107706.BRD4.SK-N-BE2-C_Resistant-veh 434 bp overlap
CHD1 1 dataset
ChIP WA01 ENCSR000AQK.CHD1.WA01 181 bp overlap
CHD7 4 datasets
ChIP WA01 ENCSR000AVA.CHD7.WA01 134 bp overlap
ChIP WA01 ENCSR000AVA.CHD7.WA01 147 bp overlap
ChIP hiPSC_AF22_abD3F5 GSE108506.CHD7.hiPSC_AF22_abD3F5 375 bp overlap
ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 510 bp overlap
CTCF 3 datasets
ChIP hESC_NAIVE GSE69646.CTCF.hESC_NAIVE 101 bp overlap
ChIP type B pancreatic cell ENCFF910FNQ 379 bp overlap
ChIP type B pancreatic cell ENCFF910FNQ 180 bp overlap
CTNNB1 1 dataset
ChIP hESC_activinA_15h GSE99202.CTNNB1.hESC_activinA_15h 348 bp overlap
EOMES 2 datasets
Motif DE_12h DE_12h-EOMES_MA0800.2 9 bp overlap
Motif ES_0h ES_0h-EOMES_MA0800.2 9 bp overlap
EP300 1 dataset
ChIP WA01 ENCSR000BKK.EP300.WA01 125 bp overlap
ESR2 1 dataset
Motif DE_12h DE_12h-ESR2_MA0258.2 15 bp overlap
ETS1 1 dataset
ChIP hESC ENCSR534VHI.ETS1.hESC 160 bp overlap
EWSR1-FLI1 3 datasets
Motif DE_12h DE_12h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_12h DE_12h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif ES_0h ES_0h-EWSR1-FLI1_MA0149.1 18 bp overlap
Elf5 1 dataset
Motif DE_12h DE_12h-Elf5_MA0136.4 8 bp overlap
Esrrg 2 datasets
Motif DE_12h DE_12h-Esrrg_MA0643.2 9 bp overlap
Motif ES_0h ES_0h-Esrrg_MA0643.2 9 bp overlap
FOXH1 2 datasets
Motif DE_12h DE_12h-FOXH1_MA0479.2 8 bp overlap
Motif ES_0h ES_0h-FOXH1_MA0479.2 8 bp overlap
FOXO6 1 dataset
Motif DE_12h DE_12h-FOXO6_MA0849.1 7 bp overlap
FOXP1 1 dataset
ChIP H9 GSE31006.FOXP1.H9 157 bp overlap
HDAC2 2 datasets
ChIP WA01 ENCSR000BNR.HDAC2.WA01 155 bp overlap
ChIP WA01 ENCSR000AVB.HDAC2.WA01 139 bp overlap
HOXB4 1 dataset
Motif DE_12h DE_12h-HOXB4_MA1499.2 6 bp overlap
HOXC4 1 dataset
Motif DE_12h DE_12h-HOXC4_MA1504.2 6 bp overlap
HOXD3 1 dataset
Motif DE_12h DE_12h-HOXD3_MA0912.2 8 bp overlap
HOXD4 1 dataset
Motif DE_12h DE_12h-HOXD4_MA1507.2 6 bp overlap
Hand1 2 datasets
Motif DE_12h DE_12h-Hand1_MA2123.1 9 bp overlap
Motif ES_0h ES_0h-Hand1_MA2123.1 9 bp overlap
Hmga1 1 dataset
Motif DE_12h DE_12h-Hmga1_MA2124.1 8 bp overlap
LIN54 1 dataset
Motif DE_12h DE_12h-LIN54_MA0619.2 7 bp overlap
Lhx1 1 dataset
Motif DE_12h DE_12h-Lhx1_MA1518.3 10 bp overlap
MAX 1 dataset
ChIP WA01 ENCSR000EUP.MAX.WA01 146 bp overlap
MGA 2 datasets
Motif DE_12h DE_12h-MGA_MA0801.1 8 bp overlap
Motif ES_0h ES_0h-MGA_MA0801.1 8 bp overlap
MORC2 1 dataset
ChIP H9 GSE95374.MORC2.H9 298 bp overlap
MXI1 1 dataset
Motif DE_12h DE_12h-MXI1_MA1108.3 6 bp overlap
MYCN 2 datasets
ChIP LA-N-5 GSE138295.MYCN.LA-N-5 275 bp overlap
ChIP NB-1643 GSE138295.MYCN.NB-1643 239 bp overlap
NANOG 11 datasets
ChIP GM23338 ENCFF065NZG 311 bp overlap
ChIP GM23338 ENCSR061DGF.NANOG.GM23338 233 bp overlap
ChIP H1 ENCFF747ZPQ 241 bp overlap
ChIP HUES-8 GSE109524.NANOG.HUES-8 510 bp overlap
ChIP WA01 ERP004238.NANOG.WA01 510 bp overlap
ChIP WA01 ENCSR000BMT.NANOG.WA01 234 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 510 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 510 bp overlap
ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 510 bp overlap
ChIP hESC GSE20650.NANOG.hESC 346 bp overlap
ChIP hESC GSE18292.NANOG.hESC 170 bp overlap
NELFE 1 dataset
ChIP HeLa GSE125534.NELFE.HeLa 119 bp overlap
NIPBL 5 datasets
ChIP WA09 GSE105028.NIPBL.WA09 260 bp overlap
ChIP hESC GSE64758.NIPBL.hESC 285 bp overlap
ChIP hESC_WNT3A GSE64758.NIPBL.hESC_WNT3A 247 bp overlap
ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 239 bp overlap
ChIP hESC_activin GSE64758.NIPBL.hESC_activin 240 bp overlap
NR1D1 1 dataset
Motif DE_12h DE_12h-NR1D1_MA1531.2 14 bp overlap
NR2C1 2 datasets
Motif DE_12h DE_12h-NR2C1_MA1535.2 6 bp overlap
Motif ES_0h ES_0h-NR2C1_MA1535.2 6 bp overlap
NR2C2 2 datasets
Motif DE_12h DE_12h-NR2C2_MA1536.2 6 bp overlap
Motif ES_0h ES_0h-NR2C2_MA1536.2 6 bp overlap
NR2F2 2 datasets
Motif DE_12h DE_12h-NR2F2_MA1111.2 7 bp overlap
Motif ES_0h ES_0h-NR2F2_MA1111.2 7 bp overlap
NR4A1 2 datasets
Motif DE_12h DE_12h-NR4A1_MA1112.3 8 bp overlap
Motif ES_0h ES_0h-NR4A1_MA1112.3 8 bp overlap
NR4A2 2 datasets
Motif DE_12h DE_12h-NR4A2_MA0160.3 8 bp overlap
Motif ES_0h ES_0h-NR4A2_MA0160.3 8 bp overlap
NR4A2::RXRA 1 dataset
Motif DE_12h DE_12h-NR4A2RXRA_MA1147.2 13 bp overlap
Nfatc2 1 dataset
Motif DE_12h DE_12h-Nfatc2_MA0152.3 8 bp overlap
Nr1H2 2 datasets
Motif DE_12h DE_12h-Nr1H2_MA1996.2 6 bp overlap
Motif ES_0h ES_0h-Nr1H2_MA1996.2 6 bp overlap
Nr1H4 2 datasets
Motif DE_12h DE_12h-Nr1H4_MA1110.3 6 bp overlap
Motif ES_0h ES_0h-Nr1H4_MA1110.3 6 bp overlap
Nr1h3 2 datasets
Motif DE_12h DE_12h-Nr1h3_MA2337.1 6 bp overlap
Motif ES_0h ES_0h-Nr1h3_MA2337.1 6 bp overlap
Nr2F6 2 datasets
Motif DE_12h DE_12h-Nr2F6_MA0728.1 15 bp overlap
Motif ES_0h ES_0h-Nr2F6_MA0728.1 15 bp overlap
ONECUT1 1 dataset
ChIP liver ERP002306.ONECUT1.liver 105 bp overlap
PBX1 2 datasets
Motif DE_12h DE_12h-PBX1_MA0070.2 9 bp overlap
Motif ES_0h ES_0h-PBX1_MA0070.2 9 bp overlap
PITX3 1 dataset
ChIP SH-SY5Y GSE93275.PITX3.SH-SY5Y 373 bp overlap
POU2F1::SOX2 1 dataset
Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap
POU2F3 1 dataset
ChIP NCI-H1048 GSE115123.POU2F3.NCI-H1048 144 bp overlap
POU3F3 2 datasets
Motif DE_12h DE_12h-POU3F3_MA0788.1 13 bp overlap
Motif ES_0h ES_0h-POU3F3_MA0788.1 13 bp overlap
POU4F2 2 datasets
Motif DE_12h DE_12h-POU4F2_MA0683.2 15 bp overlap
Motif ES_0h ES_0h-POU4F2_MA0683.2 15 bp overlap
POU5F1 12 datasets
ChIP HUES-8 GSE109524.POU5F1.HUES-8 510 bp overlap
ChIP NCCIT GSE36134.POU5F1.NCCIT 483 bp overlap
ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 510 bp overlap
ChIP OSKM GSE81899.POU5F1.OSKM 159 bp overlap
ChIP WA01 ENCSR000BMU.POU5F1.WA01 154 bp overlap
ChIP WA09 GSE105028.POU5F1.WA09 328 bp overlap
ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 297 bp overlap
ChIP hESC ENCSR264RJX.POU5F1.hESC 227 bp overlap
ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 510 bp overlap
ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 510 bp overlap
ChIP hiPSC GSE56567.POU5F1.hiPSC 271 bp overlap
ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 238 bp overlap
POU6F1 1 dataset
Motif DE_12h DE_12h-POU6F1_MA1549.2 7 bp overlap
POU6F2 1 dataset
Motif DE_12h DE_12h-POU6F2_MA0793.2 9 bp overlap
PRDM14 1 dataset
ChIP primordial-germ-cell-like-cell GSE138674.PRDM14.primordial-germ-cell-like-cell 259 bp overlap
PRDM9 1 dataset
Motif DE_12h DE_12h-PRDM9_MA1723.2 20 bp overlap
Ppara 2 datasets
Motif DE_12h DE_12h-Ppara_MA2338.1 7 bp overlap
Motif ES_0h ES_0h-Ppara_MA2338.1 7 bp overlap
Prdm5 1 dataset
Motif DE_12h DE_12h-Prdm5_MA1999.2 11 bp overlap
RAD21 5 datasets
ChIP H1 ENCFF698EWO 241 bp overlap
ChIP H1 ENCFF967OJF 245 bp overlap
ChIP WA09 GSE105028.RAD21.WA09 276 bp overlap
ChIP WA09_heat-shock GSE105028.RAD21.WA09_heat-shock 192 bp overlap
ChIP hiPSC_IIA12 GSE106870.RAD21.hiPSC_IIA12 136 bp overlap
RARA 4 datasets
Motif DE_12h DE_12h-RARA_MA0729.1 18 bp overlap
Motif DE_12h DE_12h-RARA_MA0729.1 18 bp overlap
Motif DE_12h DE_12h-RARA_MA0730.1 17 bp overlap
Motif ES_0h ES_0h-RARA_MA0730.1 17 bp overlap
RARA::RXRA 2 datasets
Motif DE_12h DE_12h-RARARXRA_MA0159.1 17 bp overlap
Motif ES_0h ES_0h-RARARXRA_MA0159.1 17 bp overlap
RARA::RXRG 2 datasets
Motif DE_12h DE_12h-RARARXRG_MA1149.2 17 bp overlap
Motif ES_0h ES_0h-RARARXRG_MA1149.2 17 bp overlap
RCOR1 1 dataset
ChIP SK-N-SH ENCSR009TKN.RCOR1.SK-N-SH 170 bp overlap
REST 1 dataset
Motif DE_12h DE_12h-REST_MA0138.3 20 bp overlap
RNF2 1 dataset
ChIP WA09 GSE105028.RNF2.WA09 248 bp overlap
RORA 1 dataset
Motif DE_12h DE_12h-RORA_MA0072.2 11 bp overlap
Rarb 5 datasets
Motif DE_12h DE_12h-Rarb_MA0857.1 16 bp overlap
Motif DE_12h DE_12h-Rarb_MA0857.1 16 bp overlap
Motif DE_12h DE_12h-Rarb_MA0858.1 17 bp overlap
Motif ES_0h ES_0h-Rarb_MA0857.1 16 bp overlap
Motif ES_0h ES_0h-Rarb_MA0858.1 17 bp overlap
Rarg 2 datasets
Motif DE_12h DE_12h-Rarg_MA0859.2 15 bp overlap
Motif ES_0h ES_0h-Rarg_MA0859.2 15 bp overlap
SALL3 1 dataset
ChIP hiPSC GSE104863.SALL3.hiPSC 440 bp overlap
SMAD1 2 datasets
ChIP BG03 GSE36578.SMAD1.BG03 96 bp overlap
ChIP BG03 GSE36578.SMAD1.BG03 106 bp overlap
SMAD2 2 datasets
ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 466 bp overlap
ChIP hESC_activinA_15h GSE99202.SMAD2.hESC_activinA_15h 375 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 384 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 141 bp overlap
SMAD2_3 1 dataset
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 261 bp overlap
SMAD3 1 dataset
ChIP BG03 GSE21614.SMAD3.BG03 205 bp overlap
SMARCA4 5 datasets
ChIP NSC GSE125033.SMARCA4.NSC 255 bp overlap
ChIP WA09 GSE105028.SMARCA4.WA09 325 bp overlap
ChIP WA09_heat-shock GSE105028.SMARCA4.WA09_heat-shock 434 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 484 bp overlap
ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 509 bp overlap
SMARCB1 2 datasets
ChIP hiPSC GSE124903.SMARCB1.hiPSC 489 bp overlap
ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 462 bp overlap
SMARCC1 3 datasets
ChIP ESC S25-ESC-d0-BAF155-exp1 393 bp overlap
ChIP hiPSC GSE124903.SMARCC1.hiPSC 190 bp overlap
ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 505 bp overlap
SOX2 4 datasets
ChIP H9 GSE46837.SOX2.H9 195 bp overlap
ChIP HNSC GSE69479.SOX2.HNSC 510 bp overlap
ChIP hESC GSE69479.SOX2.hESC 203 bp overlap
ChIP hiPSC GSE56567.SOX2.hiPSC 510 bp overlap
SP1 1 dataset
ChIP WA01 ENCSR000BIR.SP1.WA01 163 bp overlap
Stat4 1 dataset
Motif DE_12h DE_12h-Stat4_MA0518.2 10 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 192 bp overlap
TBP 2 datasets
ChIP hESC_10h GSE122298.TBP.hESC_10h 150 bp overlap
ChIP hiPSC_WTb_RNase-neg GSE128135.TBP.hiPSC_WTb_RNase-neg 242 bp overlap
TBR1 2 datasets
Motif DE_12h DE_12h-TBR1_MA0802.2 9 bp overlap
Motif ES_0h ES_0h-TBR1_MA0802.2 9 bp overlap
TBX1 2 datasets
Motif DE_12h DE_12h-TBX1_MA0805.1 8 bp overlap
Motif ES_0h ES_0h-TBX1_MA0805.1 8 bp overlap
TBX15 2 datasets
Motif DE_12h DE_12h-TBX15_MA0803.1 8 bp overlap
Motif ES_0h ES_0h-TBX15_MA0803.1 8 bp overlap
TBX18 2 datasets
Motif DE_12h DE_12h-TBX18_MA1565.2 9 bp overlap
Motif ES_0h ES_0h-TBX18_MA1565.2 9 bp overlap
TBX2 2 datasets
Motif DE_12h DE_12h-TBX2_MA0688.2 9 bp overlap
Motif ES_0h ES_0h-TBX2_MA0688.2 9 bp overlap
TBX20 3 datasets
Motif DE_12h DE_12h-TBX20_MA0689.1 11 bp overlap
Motif DE_12h DE_12h-TBX20_MA0689.1 11 bp overlap
Motif ES_0h ES_0h-TBX20_MA0689.1 11 bp overlap
TBX21 2 datasets
Motif DE_12h DE_12h-TBX21_MA0690.3 10 bp overlap
Motif ES_0h ES_0h-TBX21_MA0690.3 10 bp overlap
TBX3 2 datasets
Motif DE_12h DE_12h-TBX3_MA1566.3 9 bp overlap
Motif ES_0h ES_0h-TBX3_MA1566.3 9 bp overlap
TBX5 2 datasets
Motif DE_12h DE_12h-TBX5_MA0807.1 8 bp overlap
Motif ES_0h ES_0h-TBX5_MA0807.1 8 bp overlap
TCF12 1 dataset
ChIP WA01 ENCSR000BIT.TCF12.WA01 109 bp overlap
TCF3 1 dataset
ChIP NPC GSE154479.TCF3.NPC 333 bp overlap
TFAP2A 2 datasets
Motif DE_12h DE_12h-TFAP2A_MA0810.2 11 bp overlap
Motif ES_0h ES_0h-TFAP2A_MA0810.2 11 bp overlap
TFAP2B 2 datasets
Motif DE_12h DE_12h-TFAP2B_MA0811.2 11 bp overlap
Motif ES_0h ES_0h-TFAP2B_MA0811.2 11 bp overlap
TFAP2C 3 datasets
Motif DE_12h DE_12h-TFAP2C_MA0524.3 11 bp overlap
Motif ES_0h ES_0h-TFAP2C_MA0524.3 11 bp overlap
ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 510 bp overlap
TP63 1 dataset
Motif DE_12h DE_12h-TP63_MA0525.2 18 bp overlap
TP73 1 dataset
Motif DE_12h DE_12h-TP73_MA0861.2 16 bp overlap
TRERF1 1 dataset
ChIP WTC11 ENCFF113BUM 245 bp overlap
Tbx6 2 datasets
Motif DE_12h DE_12h-Tbx6_MA1567.3 9 bp overlap
Motif ES_0h ES_0h-Tbx6_MA1567.3 9 bp overlap
YY1 1 dataset
ChIP WA01 ENCSR000BKD.YY1.WA01 166 bp overlap
ZBTB6 1 dataset
Motif DE_12h DE_12h-ZBTB6_MA1581.2 9 bp overlap
ZNF114 1 dataset
ChIP GM23338 ENCFF631OSW 214 bp overlap
ZNF24 2 datasets
Motif DE_12h DE_12h-ZNF24_MA1124.1 13 bp overlap
Motif ES_0h ES_0h-ZNF24_MA1124.1 13 bp overlap
ZNF257 2 datasets
Motif DE_12h DE_12h-ZNF257_MA1710.2 10 bp overlap
Motif ES_0h ES_0h-ZNF257_MA1710.2 10 bp overlap
ZNF317 1 dataset
Motif DE_12h DE_12h-ZNF317_MA1593.2 8 bp overlap
ZNF331 2 datasets
Motif DE_12h DE_12h-ZNF331_MA1726.2 10 bp overlap
Motif ES_0h ES_0h-ZNF331_MA1726.2 10 bp overlap
ZNF354C 2 datasets
Motif DE_12h DE_12h-ZNF354C_MA0130.1 6 bp overlap
Motif ES_0h ES_0h-ZNF354C_MA0130.1 6 bp overlap
ZNF462 2 datasets
ChIP GM23338 ENCFF896CCA 247 bp overlap
ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 391 bp overlap
ZNF784 1 dataset
Motif DE_12h DE_12h-ZNF784_MA1717.2 8 bp overlap
ZNF816 1 dataset
Motif DE_12h DE_12h-ZNF816_MA1719.2 15 bp overlap
ZNF85 2 datasets
Motif DE_12h DE_12h-ZNF85_MA1720.2 12 bp overlap
Motif ES_0h ES_0h-ZNF85_MA1720.2 12 bp overlap
ZSCAN4 1 dataset
Motif DE_12h DE_12h-ZSCAN4_MA1155.1 15 bp overlap
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